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Transcript of Bookman.GIRLeadInstitute.2016.v3.distro
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The research mission…...in contexts
richard j. bookman, [email protected]@rbookmanhttp://slideshare.net/rbookman
2016 AAMC GIR Leadership Institute2 March 2016
http://www.gerhardrichterpainting.com/wp-content/uploads/2012/01/gerhardrichter_photo3.jpg
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disclosures
I have no financial interest in any of the content presented today.
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learning objectives
• Understand the current operating model of research in an AMC, how it got that way, and where it might be going.
• Understand some of the challenges and issues researchers, research deans, & IT teams typically face.
• Understand opportunities for IT teams to enhance both the research mission & its sustainability.
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<outline>
OverturePastPresentFuture
</outline>
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<overture>
<body>
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research is a human activity
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http://www.stanford.edu/group/vista/cgi-bin/FOV/wp-content/uploads/2012/02/tables1.png
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“Science is the belief in the ignorance of experts.”
Richard Feynman,“What is Science?”, address to science teachers, 1966
http://img.youtube.com/vi/_ah7f-1M2Sg/hqdefault.jpg
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</overture>
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<research.past>
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research 1.0
//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?
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http://pics-about-space.com/ancient-greek-astronomy?p=3#
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research does not advance unless & untilinformation
can be stored,organized, retrieved,& shared
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</research.past>
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<research.present>
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research 2.0
//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?
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“ask not what your country…”jfk,
1961 inauguration speech
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http://www.nature.com/nrc/journal/v1/n3/box/nrc1201-240a_BX1.html
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Vannevar Bush, Science, The Endless Frontier
"Discoveries pertinent to medical progress have often come from remote and unexpected sources, and it is certain that this will be true in the future. It is wholly probable that progress in the treatment of cardiovascular disease, renal disease, cancer, and similar refractory diseases will be made as the result of fundamental discoveries in subjects unrelated to those diseases, and perhaps entirely unexpected by the investigator. Further progress requires that the entire front of medicine and the underlying sciences of chemistry, physics, anatomy, biochemistry, physiology, pharmacology, bacteriology, pathology, parasitology, etc., be broadly developed."
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http://www.aaas.org/sites/default/files/FunctionNON_0.jpg
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what is the mission of an AMC?
disseminate knowledgecreate knowledge
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AMC’s 3 missions
Research
Clinical CareTraining
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AMC’s 3 missions
Research
Clinical CareTraining
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What is the balance of missions at your institution research?
<discussion question>
</discussion question>
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Hypothesis-driven vs.
discovery-driven research
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3 types of research
basic
clinicaltranslational
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basic
clinicaltranslational
3 types of research
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basic
clinicaltranslational
implementationscience
public health
3 types of research
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what is the balance of research types at your institution?
<discussion question>
</discussion question>
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The research cycle…
writeproposals
publish papers
do research
Grad students & postdocs enter cycle here…
get funding
34
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composition of the research team
PIPostdocsgrad studentslab techsclinical research coordinators& many others
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inside the mind of a PI
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researchers & administrationshare a mission
http://www.dailymail.co.uk/news/article-3045359/Tensions-close-friends-Marco-Rubio-Jeb-Bush-rise-race-White-House-heats-up.html
but don’t always see things the same way
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financing the research mission
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show me the moneysome key facts
• OPM is key• OPM comes in 3 main flavors:
internal cross-subsidization philanthropy grants
• NIH grants are the gold coin of the realm
• grants have both direct and indirect costs
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“it’s my money, and I’ll spend it any way I like.”
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https://members.aamc.org/eweb/upload/Academic%20Medicine%20Investment%20in%20Medical%20Research.pdf
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regulatingthe research mission
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regulatory requirements for clinical research
(after Sam Tilden, UAB)
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What are the key IT pain-points for each type of research?
<discussion question>
</discussion question>
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enhancingthe research mission
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• leading edge research requires high performance, high throughput, and highly flexible computing capabilities
• regulatory environment requires role-based access to integrated data from multiple institutional (and even non-institutional) systems
• smart execution of research strategy requires tracking every detail of the research operation
• sandboxes
• interoperability is key
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research does not advance unless & untilinformation
can be stored,organized, retrieved,shared, &reused!
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research 2.x
//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?
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</research.present>
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<research.future>
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research 3.0b
//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?
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Terms of UseSee this page for info, including copyright
http://gowers.wordpress.com/2009/02/01/a-combinatorial-approach-to-density-hales-jewett/
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http://www.patientslikeme.com/about
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http://www.patientslikeme.com/about
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http://www.pnas.org/content/105/6/2052
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http://www.nature.com/nbt/journal/v29/n5/full/nbt.1837.html
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“Patient engagement is the blockbuster drug of
the 21st century”Leonard Kish
http://www.hl7standards.com/blog/2012/08/28/drug-of-the-century/
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http://www.galaxyzoo.org/
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how are your researchers using the internet for research or
for professional communication?any issues?
<discussion question>
</discussion question>
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http://doi.ieeecomputersociety.org/10.1109/MIS.2009.36
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to share or not to share,THAT is the question
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got any issues around data-sharing?
<discussion question>
</discussion question>
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//computable papers
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research 3.0b
//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?
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</research.future>
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//my appeal to you
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learning objectives
• Understand the current operating model of research in an AMC, how it got that way, and where it might be going.
• Understand some of the challenges and issues researchers, research deans, & IT teams typically face.
• Understand opportunities for IT teams to enhance both the research mission & its sustainability.
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</body>
//thank you