Bone Growth & Repair Model

Trauma

Damage to blood vessels

Fibroblasts

Start of Callus

Osteoblasts

OsteoclastsCallus to bone

Immaturebone

Ossification Maturebone

Bone Repair Cycle

1.Trauma-Damage to blood vessels

Bone Repair Cycle

FibroblastsStart of CallusOsteoblasts

Bone Repair Cycle

OsteoblastsStressOsteoclasts

Bone Repair Cycle

Callus to boneRemodeling

Bone Repair Cycle1.Trauma-Damage to blood vessels2.Fibroblasts3.Start of Callus4.Osteoblasts5.Stress6.Osteoclasts7.Callus to bone

Bone Repair Cycle8. Wolf’s law: a bone will adapt to mechanical stresses and strains by changing size, shape and structure. Therefore once the cast is removed, the bone must be subjected to normal stresses and strains so that the tensile strength can be regained before the healing process is complete.

Tissue Response to Trauma

Tissue Repair DiagramTrauma

Primary InjuryBlood, damaged tissue

Acute Inflammation

Remodeling

Atrophy

Rehab

Secondary Response

Repair Phase

necrosisHematoma

AdequateInadequate

Optimal Recovery

Return to full activityReturn to full activity

Less than optimal Recovery

Reduced risk of injuryIncreased risk of injury

Pain Spasms

Tissue Repair5 signs of injury (AKA: ?????)1. Red2. Swelling3. Heat4. Pain5. Loss of function