Blood Clot formation
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Transcript of Blood Clot formation
BLOOD CLOT FORMATION
Blood clots => Blood clots are clumps that occur when
blood hardens from a liquid to a solid.
Where do they occur?
• Deep veins ( usually in lower legs)
• Lungs
• Brain
What are the symptoms?
• Inflammation develops
• Swelling
• Redness
• Gradual increase in pain ( sharp pain)
• Leg cramps
• Warmness of the skin near the clot
• Discoloration
Causes• Prolonged inactivity
• Recent surgery
• During and after pregnancy
• Not having enough water in your body (dehydration)
• Taking birth control pills or estrogen hormones (especially in
women who smoke)
• Recent trauma
• Obesity
• Cancer
• Genetically acquired blood clotting disorders
• Damage to blood vessels and changes in normal blood flow
How are blood clots detected?
• Venography
• Ultrasound
• MRIs and CAT scans
How can you treat them?
• Medication
Can blood clots kill you?
How can you prevent them?
What is a platelet?
• A platelet is a disc-shaped element in the blood that is involved in blood clotting.
They aggregate (clump together) during normal blood clotting. (Plug)
What is fibrin?
• Fibrin is an insoluble protein involved in blood clotting. Fibrin is deposited around the
wound in a form of mesh to strengthen the platelet plug. (Acts like glue)
What is Coagulation factors (clotting factors)
• Coagulation factors are proteins, mostly manufactured by the liver. Any of various
plasma components involved in the clotting of blood, including fibrinogen,
prothrombin, thromboplastic, and calcium ion. (Reinforce platelet)
Disease
A blood clot may block an artery or vein in the heart, affecting the:
Heart (angina or a heart attack)
Intestines (mesenteric ischemia) or (mesenteric venous thrombosis)
Kidneys (renal vein thrombosis)
Legs (deep vein thrombosis)
Lungs (pulmonary embolism)
Neck or brain (stroke)