Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf ·...

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Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati & Sharoot Malik Chemotherapy Agents Methotrexate Uses: Cancer and rheumatoid arthritis Complications: Mouth ulcers, methotrexate fog Cyclophosphamide Uses: Cancer, rheumatoid arthritis, lupus erythematosus and scleroderma Complications: Sores in the oral cavity and skin color change Oral Mucositis Role of Dental Hygienist Suggest mouthwash containing lidocaine or salt water rinse Accurate evaluation and early management Increase hydration Avoid alcohol Appropriate oral hygiene education Salivary substitutes Oral cryotherapy Cleaning of teeth and dentures twice a day with soft bristle toothbrush Conclusion Dental hygienists play a pivotal role before, during and after the chemo and bio therapy thus making a marked difference in treatment management and improved quality of life of the patients. Biotherapy Agents Rituximab Uses: Cancer, lupus and rheumatoid arthritis Complications: Sores on lips and oral cavity, pustules, blisters and peeling skin Belimumab Use: Systemic lupus erythematosus Complications: Risk of infections, allergic reaction, swelling of mouth, tongue and throat Mild oral mucositis Moderate oral mucositis Redness Swelling & Redness and swelling painful sore Normal, healthy mouth

Transcript of Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf ·...

Page 1: Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf · Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati & Sharoot Malik

Biotherapy and Chemotherapy: Oral Complications

Sumaiya Kasbati & Sharoot Malik

Chemotherapy Agents

Methotrexate

• Uses: Cancer and rheumatoid arthritis

• Complications: Mouth ulcers, methotrexate

fog

Cyclophosphamide

• Uses: Cancer, rheumatoid arthritis, lupus

erythematosus and scleroderma

• Complications: Sores in the oral cavity and

skin color change

Oral Mucositis

Role of Dental Hygienist

• Suggest mouthwash containing lidocaine or

salt water rinse

• Accurate evaluation and early

management

• Increase hydration

• Avoid alcohol

• Appropriate oral hygiene education

• Salivary substitutes

• Oral cryotherapy

• Cleaning of teeth and dentures twice a day

with soft bristle toothbrush

Conclusion

Dental hygienists play a pivotal role

before, during and after the chemo and

bio therapy thus making a marked

difference in treatment management and

improved quality of life of the patients.

Biotherapy Agents

Rituximab

• Uses: Cancer, lupus and rheumatoid arthritis

• Complications: Sores on lips and oral cavity,

pustules, blisters and peeling skin

Belimumab

• Use: Systemic lupus erythematosus

• Complications: Risk of infections, allergic

reaction, swelling of mouth, tongue and

throat

Mild oral mucositis

Moderate

oral mucositis

Redness Swelling &

Redness

and swelling painful sore

Normal,

healthy mouth

Page 2: Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf · Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati & Sharoot Malik

References

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