Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf ·...
Transcript of Biotherapy and Chemotherapy: Oral Complications Sumaiya Kasbati ... brochure_sumaiya sherry.pdf ·...
Biotherapy and Chemotherapy: Oral Complications
Sumaiya Kasbati & Sharoot Malik
Chemotherapy Agents
Methotrexate
• Uses: Cancer and rheumatoid arthritis
• Complications: Mouth ulcers, methotrexate
fog
Cyclophosphamide
• Uses: Cancer, rheumatoid arthritis, lupus
erythematosus and scleroderma
• Complications: Sores in the oral cavity and
skin color change
Oral Mucositis
Role of Dental Hygienist
• Suggest mouthwash containing lidocaine or
salt water rinse
• Accurate evaluation and early
management
• Increase hydration
• Avoid alcohol
• Appropriate oral hygiene education
• Salivary substitutes
• Oral cryotherapy
• Cleaning of teeth and dentures twice a day
with soft bristle toothbrush
Conclusion
Dental hygienists play a pivotal role
before, during and after the chemo and
bio therapy thus making a marked
difference in treatment management and
improved quality of life of the patients.
Biotherapy Agents
Rituximab
• Uses: Cancer, lupus and rheumatoid arthritis
• Complications: Sores on lips and oral cavity,
pustules, blisters and peeling skin
Belimumab
• Use: Systemic lupus erythematosus
• Complications: Risk of infections, allergic
reaction, swelling of mouth, tongue and
throat
Mild oral mucositis
Moderate
oral mucositis
Redness Swelling &
Redness
and swelling painful sore
Normal,
healthy mouth
References
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2015/rituxan/ NRAS - National rheumatoid arthritis society. (n.d.). Retrieved from http://www.nras.org.uk/ra-medication-and-the-mouth Pearce, L. (2016). Systemic lupus erythematosus. Nursing Standard, 30(43), 17-17. doi:10.7748/ns.30.43.17.s21 Taichman, L. S., Gomez, G., & Inglehart, M. R. (2014). Oral Health-Related Co plicatio s of Breast Ca cer Treat e t: Assessi g De tal Hygie ists’ K owledge a d
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