Biostatistics & Bioinformatics
Transcript of Biostatistics & Bioinformatics
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Biostatistics and Bioinformatics Shared Resource (BBSR)Dr. Christopher LoffredoCo Director Kepher Makambi, PhDCo Director
Statistical analysis Clinical Trials Support
Bioinformatics
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BBSR Services
Biostatistics and Bioinformatics provide:
• Support for data analysis from basic science, clinical, and population science research projects.
• Support for planning, analysis, and monitoring of clinical trials.
• Support for grant proposals, including power and sample size estimation, and data analysis planning.
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Examples of Science Supported by the BBSR
Microarray analysis
Proteomic and
Metabolomic analysis
Models of Cancer Risk
Efficacy of randomized treatment
Forecasting of cancer
trends
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Hardware Resources•Dell desktop-class computers: Windows and Linux OS
•Central processing and file storage servers: 64bit AMD Opterons running RedHat Enterprise
•Quad-core computer: dedicated to web applications
•Development servers: 2 Quad-Core Intel CPUs, using CentOS 5.0 Linux to support Oracle 11g, MySQL 5.0, PostgreSQL, a Web server (Apache), an application server (JBOSS), and development tools.
All applications are scalable to meet the needs of users
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Software Resources
•General: SAS, GAUSS, MATHEMATICA, STATISTICA, StatXact, R, MATLAB, SPSS
•Experimental Design: Simon’s Phase II, PS, NQuery, StPlan, Bayesian Plans for Phase II Trials, Power and Precision
•Specialized Packages: CART, Mplus
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Software Resources
•Bioinformatics: Bioconductor, DCHIP, PDQuest, PAUP, BRB-Array Tools
•Database: MySQL, Oracle, Oracle Jdeveloper
•Programming: Java, IMSL, Perl, PHP, VB/ASP, Weka, C, C++
•Optimization: MOZEK
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For More Information
Contact Christopher Loffredo,PhD, [email protected] or
Kepher Makambi, PhDCo [email protected]
Caroline Wu [email protected]
http://lombardi.georgetown.edu/research/sharedresources/bbsr/index.html
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Shared Resources are partially supported by the Georgetown Howard University Center for Clinical and Translational Studies (GHUCCTS) 1UL1RR031975-01
In your publications, remember to mention support provided from the GHUCCTS.