Biospecimen Sourcing Capabilities - Conversant Bio · 2017. 10. 7. · A growing U.S. site network...
Transcript of Biospecimen Sourcing Capabilities - Conversant Bio · 2017. 10. 7. · A growing U.S. site network...
Biospecimen Sourcing Capabilities
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A Few Things to Know About Conversant Bio
1. We are glad to be here!
2. We believe in open and honest communication in order to
build strong, lasting relationships
3. We believe in failing forward to embrace innovation and
continuous improvement
4. Everything we do is because patients are waiting . . .
What makes Conversant Bio unique?
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Our unique business model
Feature Benefit to you
We know complex projects
We handle regulatory details
80% on-demand
IRB approved
Embedded coordinators
Access to patient records
Rapid Processing
Custom tubes, custom kits
Deep clinical data
We process samples
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The only Premier Support in the
industry
Your dedicated Project Manager will:
• Confirm Order details immediately
• Provide regular updates
• Answer any questions at any time
Our Clinical Data Analysts will:
• Target patients according to your criteria
• Provide patient annotation
age, race, sex, smoking history, alcohol history, and primary
diagnosis, path reports, cyto reports, mutation data
(866) [email protected]
A growing U.S. site network
U.S. site procurement
• Hospitals and physician clinics
• Full regulatory/IRB compliance
• Consent and waiver of consent studies
• Dedicated Site Development professionals focused on growing
our capacity and capabilities
• Many new sites added to the collection network
– Fixed Formalin Paraffin Embedded Tissue and Fresh Frozen Tissue
– Fresh Bone Marrow
– Matched Cord Blood & Placenta
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Proprietary and Confidential
Why do people work with us?
Oncology
• Lung
• Breast
• CRC
• Prostate
• other tumors
• Leukemia
• Myeloma
• Lymphoma
• MGUS
• other hem/onc
Autoimmune
• Lupus
• Rheumatoid Arthritis
• Sarcoidosis
• Scleroderma
• Crohn’s Disease
• Psoriasis
• Idiopathic Pulmonary Fibrosis
Other
• Normal Controls
• Multiple Sclerosis
• Pregnancy
• Diabetes Type 2
• Specialized cells (CAF, CD34+, CD138+, etc.)
• HIV, HBV, HCV, TB
We have access to many diseases
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We have access to many diseases
Across many tissue types
Ascites Fluid
Peripheral Blood
Bone Marrow
Leukopak
Skin
Sputum
Tissue
UrineCord Blood
leu
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Fresh, frozen, and custom processed tissues from…
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Including a wide array of FFPE
• All commonly requested
oncology samples
including breast, lung,
and colorectal
• Thousands of QC’d
blocks available
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And hard to find blocks
0
20
40
60
80
100
120
Bladder Cancer Head & Neck Cancer Liver Cancer Non-Hodgkin'sLymphoma
Ovarian Cancer Pancreatic Cancer
Conversant Bio FFPE
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• Blocks generally larger because they have not been cut and re-embedded
• New sites with new inventory that has not been picked over
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• Quality control process is overseen by 2 U.S.
licensed pathologist
Conversant Bio block
Choosing your blocks . . .
Which block has the highest tumor load?
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Tumor Load 100% Tumor Load 75% Tumor Load 40%
Which block has the most utility?
• OK for <10 4um sections
• OK for 1 10um curl
• OK for whole block sale
• 1 x 13mm tumor
• OK for >100 4um sections
• OK for >20 10um curl
• OK for whole block sale
• Not ideal for arrays (shallow)
• 38 x 5mm tumor
• OK for >100 4um sections
• OK for >20 10um curl
• OK for whole block sale
• OK for TMAs (thick)
• 15 x 11mm tumor
Ordering with Us
Conversant Bio © 2014. All rights reserved.
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We provide quantitative QC block data and answer the following questions:
Does the block look to be in good condition?
Is the tissue well fixed?
Is there necrosis present?
Does the block match pathology report data?
What is the tumor percentage?
What is the tumor size?
How many 4um sections are available from the tissue present?
Cu
sto
me
rs r
ely
on
us t
o…
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• Build a 700 patient auto-immune
biorepository
• Build a 200 patient dissociated tumor
cell bank
• Beat a deadline to collect 20 AML whole
blood samples in one month
• Validate a new assay in primary cells
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Our Model
Co
nve
rsan
t B
io Prospective Collections
Banked Inventory
Lab
PBMCs Dissociated Tumor CellsPlasma Xenograft CellsSerum Ascites FluidBMMCs Buffy CoatFFPE Fresh Frozen Tissue
Oncology Infectious DiseaseAuto-Immune MetabolismPulmonology NormalsNeurology
Custom ProtocolsCell isolationFlow CytometryViral/antibacterial testingMutation Testing
Researchers enjoy our resources
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eBooks focused on helpful topics
How do we work with you?
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Step 1Project discussion, Quote, and PO approval
Step 2Project setup
Step 3Patient targetingand kits built
Step 4Samples collectedand processed
Step 5Samples shipped and data delivered
1 2 3 4 5
Inventory Orders take 2 days (average)
Prospective Orders take 7 days (average)
Ordering is simple and quick
Please consider us a resource
Phone (866) 838-2798
Email [email protected]
Web www.conversantbio.com
Visit 601 Genome Way, Huntsville, AL 35806
Contact us for any project needs