Biopotential Amplifier

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    Biopotential Amplifier

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    Other

    Biopotentials

    ECG

    EMG

    ERG

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    Si nal

    (Hz)

    range(mV)

    ECG 0.01 100 0.05 3

    EEG 0.1 80 0.001 1

    EOG 0.01 10 0.001 0.3

    EMG 50 3000 0.01 100

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    WHYFREQUENCY?

    When measuring biopotentials (say ECG), EVERYTHING else

    even other biopotentials (like EEG, EMG, EOG)

    are noise sources. These have characteristic frequencies. So use Band Pass

    ers.

    fL to fHattenuate

    fL fH

    .

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    SAFETY

    Amplifiers are powered, should not shock or electrocute the subject

    Subject Electronics

    No large current

    Ground

    .Also no potentials

    >>0 or

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    SAFETY:

    PROTECTION

    CIRCUITS

    If potential >>0, high current grounded through D1

    If potential

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    Potential transferred through optoelectronics (shown), transformers etc.

    Circuits are electrically isolated, no current leakage

    Power

    Power

    ElectronicsSubject

    Ground

    Electricity

    >

    Light

    >

    Electricity

    Provides

    electrical

    isolation

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    TELEMETRY Means wireless transmission of data from and to the device

    HOME

    No limits: can be done across the

    world. Internet will play a huge role.

    HOSPITAL

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    ECG:EinthovensTriangle

    Threevectors

    LeadsI,II,III

    usedto

    fully

    identifythe

    Vectorshownin

    frontalplane

    of

    thebody

    Kirchhoffslawis

    leads

    I+II+III=0

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    ECG:ElectrodePlacement

    Augmentedleads:

    aVR aVL aVF

    Right,left,

    foot

    Withrespecttocentral

    term na

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    ECG:TransversePlane

    Chestleads:

    V1,V6

    ChestleadsusedtoobtaintheECGinthetransverse

    lane ObtainsECGfromthe osteriorsideoftheheart

    All

    together:

    12

    leads

    (I,II,III;

    aVR,

    aVL,

    aVF,

    V1V6)

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    APPLI ATI N: F l EProblem:RecordedECG=mothersECG+

    fetusECG

    F+M

    Solution:cancel

    meaningsubtract

    mothersECGfromfetal

    ECG?

    M

    M

    .

    DN:fetusECGampl.

    fetusECGfilters

    OUT= o

    fetusECG

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    Inverting

    amplifier

    Gaininthemultiplestages:i.e.

    HighGain so,youcanamplify

    smallsignals

    Asa

    onus,

    put

    some

    lowpass

    Differential

    am lifierbut

    and

    high

    pass

    withvery

    high

    input

    impedance

    Noninverting

    amplifierSo,youcan

    connect

    to

    sensors

    rejectscommonmode

    interference

    >so

    you

    canrejectnoise

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    INSTRUMENTATIONAMPLIFIER:

    STAGE1

    Recall virtual ground of opamps

    I1 = (V1 V2)/R1

    eca no curren can en er opamps an

    Kirchoffs current law

    I2 = I3 = I1I2

    Recall Kirchoffs voltage law

    VOUT = (R1 + 2R2)(V1 V2)/R1

    I3

    1

    2 2 1

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    INSTRUMENTATIONAMPLIFIER:

    STAGE2

    Recall virtual ground of opamps and voltage

    divider

    V = V = V R / R + R-

    Recall no current can enter opamps

    (V1 V-)/R3 = (V- VOUT)/R4I2

    Solving,

    VOUT = (V1 V2)R4/R3

    I3

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    INSTRUMENTATIONAMPLIFIER:

    COMPLETE

    VOUT = (V1 V2)(1 + 2R2/R1)(R4/R3)

    Gainfrom

    Stage

    I and

    Stage

    II

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    INSTRUMENTATIONAMPLIFIER:

    COMPLETE

    Features:

    Differentialamp

    Veryhighgain

    VOUT = (V1 V2)(1 + 2R2/R1)(R4/R3)

    Very

    ig

    inputR

    Commonmode

    rejection

    Gainfrom

    Stage

    I and

    Stage

    II

    (wealsoneed

    filters)