Biological and Medical Physics

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1

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    We know the atomic-level structures of the most important biological macromolecules

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1

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    Illustration of Cricks two great polymer languages

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 4

    The chemical structure of nucleotides

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    The chemical structure of DNA

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    The chemical structure of DNA

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 7

    Genetic code

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 8

    Idealizations of DNA

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 9

    Idealizations of proteins

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 10

    Idealizations of membranes

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 12

    Idealization of a solution

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    Electron micrograph of a mitochondrion

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 14

    The network of membranes of a mitochondrion

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 15

    The electron transport and ATP synthesis in the inner membrane

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 16

    Mitochondrial division (fission)

    h h l f

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 17

    The chemical structure of DNA

    h l i i d l b d i l

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 18

    The elastic spring model can be used in several ways

    EM i f b i h

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 19

    EM image of a bacteriophage genome

    F d l i i bi l i l

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    Copyright Garland Science 2009 Copyright Syracuse University 2010Biological and Medical Physics - Lecture 1 20

    Fundamental estimates in biological systems

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    Announcements

    Phillip & Kondev & Theriots Textbook

    Chapter 1: Why: Biology by the Numbers

    Pages 3-26