BIODATANAME: Dr. HARISH KUMAR N. KAKRANIFATHER’S NAME SHRI NARAIN DAS J. KAKRANIDATE OF BIRTH 07/4/1953PLACE OF BIRTH : INDOREMARITAL STATUS: MARRIEDCONTACT NUMBER: 09879308309 EDUCATIONAL QUALIFICATIONS B.PHARM. ( 1976) …………………………….FIRST CLASS………………………………INDORE UNIVERSITY M.PHARM (1978) …………………………….FIRST CLASS………………………………..SAGAR UNIVERSITY Ph.D. (PHARM. SCIENCES) (2001)…………………………………………… S.P UNIVERSITY ,V.V NAGAR

“STUDIES ON SALINE ALKALI SOILS & MEDICINAL PLANTS OF KUTCH DISTRICT, GUJARAT STATE, INDIA ” UNDER GUIDANCE OF PROF.(DR) A.K.SALUJA, PRINCIPAL, A.R. COLLEGE OF PHARMACY, VALLABH VIDHYANAGAR.

## Recognized guide for Ph.D. in Faculty of Technology including Pharmacy of KSKV Kachchh university, Bhuj#### Recognized guide for M.Phil in Faculty of Biotechnology in Global Open University, Nagaland

AWARDS & FELLOWSHIPS Received JRF of UGC during M. Pharm studies Fellow of institute of Chemists (India) Fellow of Academy of General Education (Manipal)

MEMBERSHIP OF PROFESSIONAL & ACADEMIC BODIES Life member Indian society of Pharmacognosy Life member Association of Pharmacy Teachers Of India ( A.P.T.I.) Life member Bioinformatics Institute of India Member Indian Pharmacy Association. Member Indian Pharmacy Graduates Association Member Gujarat Pharmacy Teachers association Executive member A.P.T.I.Member, Executive Council, KSKV Kachchh UniversityMember, Acedemic Council, KSKV Kachchh UniversityMember, Senate, KSKV Kachchh University Member, Advisory committee, Tolani Institute for Excellence EXAMINERSHIPSWorked as examiner for Pune University, Berhampur University, BerhampurMysore Universty, MysoreKarnataka Universty, Dharwad,. Gulbarga University, Mangalore University,MangaloreBoard of Examining Authority, F.D.A. Karnataka Gujarat university, S.P.University , VallabhvidyanagarNorth Gujarat university, Patan, K.S.K.V. Kachchh University, BhujDr. M.G.R. Medical University, ChennaiPUBLICATIONS

BOOKS /TEXT BOOKS 1. Pharmaceutical Biotechnology , Student Edition, Agrobios (India),Jodhpur2. Pharmaceutical Microbiology, Student Edition, Agrobios (India), Jodhpur3. Pharmacognosy , frontline Publishers, Hyderabad RESEARCH PAPERS 36 research papers published in national and international Journals Honorary Executive Editor : planta indica a quarterly Journal of Plant environment & allied Sciences Editor: Tolani Campus Times EXPERTSHIPS

1. Worked as Technical Expert (PHARMACY) for Gujarat Council for Science & Technology (GUJCOST),Government of Gujarat, Gandhinagar.

2. Referee for Journal of Natural Remedies, Bangalore3. Referee for on line Journal of Pharmaceutical Biology, U.K.

PROJECTS HANDLED “Pharmaceutical studies on the Commiphora mukul gum” with J.R.F. from UGC. MODROB project from AICTE ( 5 Lacs). Border Area Development Project (Education) (73.5 lacs) MODROB project from A.I.C.T.E. (5.5 Lacs). EXPERIENCETotal 32 years Teaching and research for P.G./ U.G. and diploma courses at LECTURER : Nasik,(22/9/78- 8/6/80), LECTURER ; College Of Pharmacy, Berhampur 15/7/80-13/1/81) LECTURER : College Of Pharmaceutical Sciences, K.M.C., Manipal ( 15/1/81- 17/12/82) ASSISTANT PROFESSOR : J.N.M.C. Belgaum 20/12/82- 5/5/87) H.O.D. Tolani Institute of Pharmacy, Adipur ( 8/5/87 to 31/11/98) PRINCIPAL : at Tolani Institute of Pharmacy, Adipur ( Gujarat)( 1/12/98 to 21/12/2009) Principal , CVM Institute for degree course in Pharmacy, New Vallabh Vidyanagar 22/12/2009 till date)

LIST OF PUBLICATIONSDR. HARISH KUMAR N. KAKRANI

1. A STUDY ON BINDING PROPERTIES OF GUGGUL GUM: KAKRANI H.K.N., & JAIN N.K. INDIAN J. HOSP. PHARM. XVIII (3), 1981,P.100. ISSN - 0019 –526X: INDIAN2. SUSPENDING AND EMULSIFYING PROPERTIES OF GUGGUL GUM. KAKRANI H.K.N. , & VARMA K.C. INDIAN J.HOSP. PHARM. XVIII (4), 1981, P. 134. ISSN - 0019 –526X : INDIAN 3. GUGGUL : A REVIEW. KAKRANI H.K.N INDIAN DRUGS. 18(12),1981,P 417.

ISSN – 0019 –462 X : INDIAN4. FLAVONOIDS FROM THE FLOWERS OF COMMIPHORA MUKUL KAKRANI H.K.N. FITOTERAPIA. LI(5), 1981,P.221. ISSN 0367 –326X: ITALY5. “INVITRO” ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL FROM C. MUKUL & C. ROXBURGHII. KAKRANI H.K.N BULL.MEDICO ETHNO BOT. RES. 2(1),1981 ,P.100. INDIA 6. PHYSICO CHEMICAL PROPERTIES OF SEED OIL OF C. MUKUL KAKRANI H.K.N INDIAN DRUGS.19(8),1982,P.339 . ISSN – 0019 –462 X: INDIAN7. EFFECT OF ADMIXTURE OF MIMOSA PUDICA GUM AND STARCH PASTE ON MICRO- MERITICS OF SULPHADIAZINE GRANULES KAKRANI H.K.N EASTERN PHARMACIST, XVII (294), 1982, P117. ISSN 0012- 8872: INDIAN 8. ANTIFERTILITY AND ABORTIFACIENT ACTIVITY OF ETHANOLIC EXTRACT OF AGLAIA ODORATISSIMA ROOTS. KAKRANI H.K.N. & NAIR G.V. PROBE, XXIV(1), P. 37. INDIAN 9. ANTIFERTILITY AND ABORTIFACIENT ACTIVITY OF AERIAL PARTS OF MYRSINE AFRICANA. KAKRANI H.K.N. & KAKRANI VANDANA A. FITOTERAPIA, LII (4), 1982, P. 100. ISSN 0367 –326X; ITALY 10. ANTIINFLAMMATORY AND ANTIPYRETIC ACTIVITY OF DATISCA CANNABINA METHANOLIC EXTRACT. KAKRANI H.K.N. & NAIR G.V. FITOTERAPIA, L(III), 1982, P. 103. ISSN 0367 –326X ITALY 11. “ IN VITRO” ANTHELMINTIC ACTIVITY OF ESSENTIAL OIL OF SEEDS OF AGLAIA

ODORATISSIMA . KAKRANI H.K.N. & NAIR G.V. FITOTERAPIA, LIII (4), 1982, 111. ISSN 0367 –326X. ITALY12. ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF VOLATILE OIL FROM THE SEEDS OF AGLAIA ODORATISSIMA KAKRANI H.K.N. & NAIR GV FITOTERAPIA, LIII (4), 1982, P.107 ISSN 0367 –326X; ITALY13. ANTHELMINTIC AND PURGATIVE ACTIVITY OF MYRSINE AFRICANA FRUITS KAKRANI H.K.N. & KALYANI G.A. ANCIENT SCIENCE OF LIFE, 3(2), 1983, P. 82.INDIAN ISSN-0970 –129 X, INDIAN14. ANTIMICROBIAL AND ANTHELMINTIC ACTIVITY OF ESSENTIAL OIL OF ESSENTIAL OIL OF MESSUA FERREA. KAKRANI H.K.N, NAIR G.V., DENNIS T.J. & JAGADALE M.H. INDIAN DRUGS, 6, 1984, P. 26. ISSN – 0019 –462 X: INDIAN 15. PRELIMINARY PHARMACOLOGICAL ACTIVITY OF ESSENTIAL OIL OF C .MUKUL. KAKRANI H.K.N., BAGI M.K., KALYANI G.A., SATYANARAYANA D. & MANAVI F.V. FITOTERAPIA,LVI(3), 1985, P.245. ISSN 0367 –326X; ITALY 16. EVALUATION OF PHARMACOLOGICAL ACTIVITY OF FIXED OIL OF ABUTILON INDICUM - II ANALGESIC ACTIVITY.

KAKRANI H.K.N., BAGI M.K., KALYANI G.A. DENNIS T.J. & AKSHAYA KUMAR K. FITOTERAPIA, LVI (3), 1983, 169. ISSN 0367 –326X; ITALY 17. EVALUATION OF PHARMACOLOGICAL ACTIVITY OF FIXED OIL OF ABUTILON INDICUM-I ANALGESIC ACTIVITY. KAKRANI H.K.N., BAGI M.K., KALYANI G.A. DENNIS T.J. & AKSHAYA KUMAR K. INDIAN DRUGS,20(2), 1984, P.69. ISSN – 0019 –462 X: INDIAN 18 EFFECT OF PYROLLIZIDINE ALKALOIDS SENICIPHYLLINE AND SENECIONINE ON DRUG HEPATIC METABOLIZING ENZYMES IN RATS. KAKRANI H.K.N. & KALYANI G.A. J. ETHNOPHARMACOLOGY, 12(3), 1984, P. 271. ISSN: 0378-8741 IRELAND 19. ANTHELMINTIC ACTIVITY OF ESSENTIAL OIL OF C.MUKUL. KAKRANI H.K.N. & KALAYANI G. FITOTERAPIA, LV(4),1984,P.232. ISSN 0367 –326X; ITALY 20. EXPERIMENTAL EVALUATION OF ANTIINFLAMMATORY AND ANALGESIC ACTIVITY OF PHYLLANTHUS FRATERNUS, PETROLEUM ETHER EXTRACT. KAKRANI H.K.N., HUKKERI V.I. KALYANI G.A. & BAGI M.K. INDIAN DRUGS, 23(1), 1985, P.59. ISSN – 0019 –462 X: INDIAN21 STUDIES ON AYURVEDIC DRUGS – I : EVALUATION OF ANTIFATIGUE EFFECT OF AN AYURVEDIC DRUG ‘ALERT ‘IN RATS. KAKRANI H.K.N., NAIR G.V. SATYANARAYANA D. & KALYANI G.A. FITOTERAPIA, LVI (5), 1985,293. ISSN 0367 –326X; ITALY22.EXPERIMENTAL EVALUATION OF ANTIINFLAMMATORY ACTIVITY OF LAWSONIA ALBA SEED OIL. KAKRANI H.K.N., BAGI M.K., KALYANI G.A.,DENNIS T.J. & JAGADALE M.H. FITOTERAPIA, LIX(1), 1988, P.39. ISSN 0367 –326X; ITALY 23. DRUG INTERACTION- I : INTERACTION OF SEDATIVES & C.N.S. STIMULANTS: KAKRANI H.K.N., BAGI M.K. & KALYANI G.A. INDIAN J.PHARM. SCIENCES, 50(2), 1988, P.93.24. ORAL HYPOGLYCEMIC ACTIVITY OF FLAVONOIDS OF PHYLLANTHUS FRATERNUS IN RATS: KAKRANI H.K.N., KALYANI G.A. & HUKKERI V.I. FITOTERAPIA, LIX(1), 1988, P.68 ISSN 0367 –326X; ITALY25 HOLOTHURIN – A REVIEW. KAKRANI H.K.N., KALYANI G.A. & HUKKERI V.I. INDIAN J. NATURAL PRODUCTS, 4(2), 1988, P.3. ISSN-0970 –129 X, INDIAN26 PHARMACOGNOSTICAL INVESTIGATIONS ON THE LEAVES OF COMMIPHORA MUKUL KAKRANI H.K.N., KALYANI G.A. SATYANARAYANA D. & MANVI F.V.: ANCIENT SCIENCE OF LIFE, X(3), 1991, P.165. ISSN-0257-7941, INDIAN27. TRADITIONAL TREATMENTS THROUGH HERBAL DRUGS IN KUTCH DISTRICT,GUJARAT STATE, INDIA – PART – I UTERINE DISORDERS. KAKRANI H.K.N. & SALUJA A.K. FITOTERAPIA, LXIV (5), 1993,P.463. ISSN 0367 –326X; ITALY28 TRADITIONAL TREATMENTS THROUGH HERBAL DRUGS IN KUTCH DISTRICT, GUJARAT STATE, INDIA – PART –II ANALGESIC, ANTIINFLAMMATORY, ANTIRHEUMATIC & ANTIARTHRITIC PLANTS. KAKRANI H.K.N. & SALUJA A.K.

FITOTERAPIA, LXV(5), P.427.1994. ISSN 0367 –326X; ITALY 29 PLANTS USED FOR DIURETIC ACTIVITY IN TRADITIONAL MEDICINE IN KUTCH DISTRICT, GUJARAT . KAKRANI H.K.N.& SALUJA A.K. JOURNAL OF NATURAL REMEDIES 2(1 ),2001, P.121. ISSN- 0972-554730 TRADITIONAL TREATMENT OF GASTROINTESTINAL TRACT DISORDERS IN KUTCH DISTRICT,GUJARATSTATE,INDIA. KAKRANI H.N.K. & SALUJA A.K. JOURNAL OF NATURAL REMEDIES ,2(1),2002,71. ISSN- 0972-554731. ANTIARTHRITIC AND ANTIINFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF PERISTROPHE BICALICULATA Nees. KAKRANI H.K.N. & SALUJA A.K. PLANTA INDICA 1(1) 2005, 8 INDIAN 32. TRADITIONAL TREATMENT OF DIABETES THROUGH HERBS IN KUTCH DISTRICT, GUJARAT STATE KAKRANI H.K.N., KAKRANI BHANU H. & SALUJA A.K. PLANTA INDICA, 1(1), 2005, 16 INDIAN 33. TRADITIONAL TREATMENT OF PYREXIA IN KUTCH DISTRICT GUJARAT. KAKRANI H.K.N. & SALUJA A.K. PLANTA INDICA 1( 2 ) 2005, 36. INDIAN34. PRILIMINARY ANTIPYRETIC ACTIVITY OF METHNOLIC EXTRACT OF SOME MEDICINAL PLANTS OF KUTCH KAKRANI H.K N.. & SALUJA A.K. PLANTA INDICA 1( 2 ) 2005, 42 INDIAN35. ETHNOPHARMACOLOGY OF ARID ZONES OF INDIA: PART I - KUTCH KAKRANI H.K.N., KAKRANI BHANU H. & SALUJA A.K. PLANTA INDICA 3( 3 ) 2007, 1-4. INDIAN 36. SALT TOLERANCE CAPACITY OF S.FRUTICOSA & T.TRIQUETRA KAKRANI BHANU H., KAKRANI H.N.K. . & PUROHIT S.S. PLANTA INDICA 3( 3 ) 2007, 35-38 INDIAN37> TRADITIONAL TRAETMENTS IN KUTCH DISTRICT – PART VII ANTIBATERIAL / WOUND HEALING PLANTS PURVI   H. KAKRANI* , HARISH N. KAKRANI **  & AJAY K. SALUJA PLANTA INDICA 5( 5 ) 2010, 43 INDIAN

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PHARMACEUTICAL MICROBIOLOGY

S.S. PUROHIT, A.K. SALUJA AND H.N. KAKRANI., Agrobios, Jodhpur 2003, 596 p., tables, figs., $55. ISBN 81-7754-193-5.

    Contents: 1. Pharmaceutical microbiology: introduction and history. 2. Microscopy. 3. Classification of microbes. 4. Nature, classification, morphology and synthesis of viruses. 5. Bacteriophages. 6. Viruses of eukryotes. 7. Mycoplasmas and mycoplasmas viruses. 8. Mycobacteria, myxobacteria, rickettsiae and chlamydiae. 9. Bacteria: classification, nomenclature and identification. 10. Bacteria: eubacteria. 11. Archaeobacteria, actinomycetes, actinoplanetes and maduromycetes. 12. Spirochetes and rickettsias. 13. Eukaryota: fungi. 14. Nutrition and photosynthesis in bacteria. 15. Growth and development of microorganisms. 16. Cultivation of bacteria and viruses. 17. Microbial genetics. 18. Methods of sterilization. 19. Methods of disinfestation. 20. Antibacterial and antiviral drugs. 21. Microorganisms and diseases in man: basic concepts. 22. Salmonella. 23. Shigella. 24. Vibrio. 25. Clostridium. 26. Corynebacterium. 27. Mycobacterium. 28. Human pathogenic viruses. 29. Immunology and serology. 30. Animal vaccine: development and production. 31. Antimicrobial sensitivity tests. 32. Practical pharmaceutical microbiology. 33. Serological tests. 34. Biotransformation and steroid production. Subject index.

    From the preface: "Microbes are the part of our lives in more ways than most understand. Microbiology is one of the most applied of all the biological sciences. Microbiology can be divided into two major fields: theoretical and applied. The major fields of applied microbiology are: Medical microbiology, Aquatic microbiology, Aero-microbiology, Agricultural, Industrial microbiology, Exo-microbiology and Geochemical microbiology. Industrial and Pharmaceutical microbiology are the most promising areas of applied microbiology.

    "Health care products derived from microbial biosynthesis are antibiotics, hormones, vitamins, and vaccines. Pharmaceutical microbiologists have several tricks to increase the amount of the chosen end product. Use of industrial fermentation processes begin with microbial cells acting as living factories.

    "The present book is an attempt to provide overall information to the readers interested in pharmaceutical microbiology."    

PHARMACEUTICAL BIOTECHNOLOGY

S.S. PUROHIT, H.N. KAKRANI AND A.K. SALUJA., Agrobios, Jodhpur 2003, xvi, 528 p., figs., tables, $55. ISBN 81-7754-194-3.

  Contents: 1. Pharmaceutical biotechnology: an introduction. 2. Biological genetics and variations in characters of microbes. 3. Concepts, perspectives and techniques of microbial genetic and protein engineering. 4. Techniques of recombinant DNA technology for production of biologicals. 5. Animal cell and tissue culture. 6. Hybridomas technology and monoclonal antibodies. 7. Gene therapy. 8. Microbes in pharmaceutical industry. 9. Development of industrial microorganisms. 10. Culturing of industrial microorganisms. 11. Industrial fermenters. 12. Production of antibiotics. 13. Production of vitamins. 14. Production of ergot alkaloids. 15. Other primary metabolites of pharmaceutical uses. 16. Biotransformation and steroid production. 17. Biology of enzymes. 18. Production of enzymes. 19. Production of enzymes of fermentation. 20. Applications of enzymes. 21. Enzyme immonilization. 22. Applications of immobilized enzymes. 23. Plant tissue culture: basic concepts. 24. Plant tissue culture: methods. 25. Protoplast fusion technology. 26. DNA isolation and sequencing. 27. Gene cloning vector/plasmid. 28. Methods of gene transfer. 29. Biotechnology production of secondary plant metabolites. Appendix. Glossary. Subject index.

    From the preface: "Biotechnology in pharmaceutical industry employs techniques of modern molecular biology to help humankind. Pharmaceutical biotechnology works to make manufacturing processes more efficient in industrial production of pharmaceutical products. Biotechnology will transform the industrial sector in much the same way that it has changed the pharmaceutical sector.

    "Pharmaceutical industrial biotechnology companies develop biocatalysts, such as enzymes, to be used in chemical synthesis. Enzymes are proteins produced by all living organisms. In humans, enzymes help digest food, signal cells to turn on and off, and perform other complex functions. Enzymes are characterized according to the compounds they act upon. Some of the most common enzymes are proteases, which break down protein; cellulases, which break down cellulose; lipases, which act on fatty acids and oils; and oils and amylases, which break starch down into simple sugars. To improve the productivity-to-cost ratio, scientists are modifying genes to increase enzyme productivity in microorganisms commonly used in manufacturing. They also use genetic engineering to make other microbial enzymes that are too expensive or even impossible to cultivate. The biotechnology techniques of protein engineering and directed protein evolution have been used to modify the substrate specificity of enzymes, improve catalytic properties or broaden the reaction conditions under which enzymes can function so that they are more compatible with existing industrial processes. Companies involved in industrial biotechnology are constantly striving to discover and develop high-value enzymes and bioactive compounds that will enhance current industrial processes.

    "The present book is an attempt to provide overall information to the readers interested in Pharmaceutical Biotechnology."