Biochemistry. Macromolecules (large molecules): Carbohydrates Lipids Proteins Nucleic Acids...

58
Biochemistry Biochemistry

Transcript of Biochemistry. Macromolecules (large molecules): Carbohydrates Lipids Proteins Nucleic Acids...

Page 1: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

BiochemistryBiochemistry

Page 2: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Macromolecules (large molecules):

CarbohydratesLipidsProteinsNucleic Acids

These are Polymers (many parts)

constructed of Monomers (single part)

Page 3: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

polymerpolymer

Page 4: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

polymerpolymer

Page 5: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

monomer

Page 6: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

How to Connect Monomers-

Hydrolysis- Breaking apart polymer

Adding water molecule

Page 7: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Connecting Monomers-

Dehydration reaction

Hydrolysis- Breaking apart polymer

Adding water molecule

Page 8: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Connecting Monomers-

Dehydration reactionjoining monomersloss of water molecule

Hydrolysis- Breaking apart polymer

Adding water molecule

Page 9: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Connecting Monomers-

Dehydration reactionjoining monomersloss of water molecule

Hydrolysis- Breaking apart polymer

Adding water molecule

Page 10: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Connecting Monomers-

Dehydration reactionthis takes energy

Hydrolysis- Breaking apart polymer

Adding water molecule

Page 11: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Connecting Monomers-

Dehydration reactionthis means energy must be added in order for the reaction to occur

Putting together

Page 12: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Hydrolysis- Breaking apart polymer

Adding water molecule

Breaking apart polymersHydrolysis- (break w/ water)

Adding water molecule

Page 13: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Hydrolysis- Breaking apart polymer

Adding water molecule

Breaking apart polymersHydrolysis- (break w/ water)

Adding water molecule

Page 14: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Hydrolysis- Breaking apart polymer

Adding water molecule

Breaking apart polymersHydrolysis- (break w/ water)

Adding water molecule

Page 15: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Hydrolysis- Breaking apart polymer

Adding water molecule

Breaking apart polymersHydrolysis- (break w/ water)

Adding water molecule

Page 16: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Creating Monomers-

Hydrolysis reactionthis gives off energy when this happens

breaking

up

Page 17: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Hydrolysis- Breaking apart polymer

Adding water molecule

explain to your partner what is explain to your partner what is happeninghappening

Page 18: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.
Page 19: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Macromolecules (large molecules):

CarbohydratesCarbohydratesLipidsProteinsNucleic Acids

Page 20: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Carbohydrates-

Fuel - stores energy

functions:

Building material - >

in plantsin plants = cellulose (cell wall) in animalsin animals = chitin (insect/ lobster covering)

Page 21: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Carbohydrates- types:

Page 22: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

1)MonosaccharidesSingle Sugar

Page 23: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

MonosaccharidesStructure: Single SugarFunction: Fuel for cell work

ex. glucose - blood sugar fructose - fruit sugar

lactose - ??

Page 24: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Monosaccharides - structure:

multiple of CH2O

ex. glucose C6H12O6

Page 25: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Disaccharides

Two sugar monomers joined by dehydration synthesis

Page 26: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Disaccharides

Two sugar monomers joined by dehydration synthesis - JOIN / SPIT

OH-

Page 27: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Disaccharides

Two sugar monomers joined by dehydration synthesis

ex. sucrose - table sugar

Page 28: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

PolysaccharidesMany monomers

Page 29: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

PolysaccharidesMany monomers

Functions:

•1) Energy storage=

•starch (plant)starch (plant)

•glycogen (animal)

Page 30: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

PolysaccharidesMany monomersFunctions:

•1) Energy storage=

2) Structural support = cellulose

Page 31: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Polysaccharides

2) Structural support

= cellulose

Page 32: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.
Page 33: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Macromolecules (large molecules):

CarbohydratesLipidsProteinsNucleic Acids

Page 34: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Lipids-Lipids-

Types:

1) Fat~ triglyceride

2) Phospholipid~ cell membranes

3) Steriod

4) Wax

Page 35: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Lipids-Lipids-

Structure = have a higher ratio of C & H than Oxygen

Page 36: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

They HATE water

Therefore, are they polar or nonpolar?

Page 37: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Lipids- (hydrophobic)

1) Fats (triglyceride)1) Fats (triglyceride) - functions:

-energy storage

-cushion internal organs

-insulation

Page 38: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Types of Lipids: Fats- structure1 Glycerol

Fatty acid chain = hydrophobic

•Energy storage

•Cushion

Page 39: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Types of Lipids: Fats- structure Glycerol

Fatty acid chain = hydrophobic

•Energy storage

•Cushion

+3 fatty acid chains

Page 40: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

http://www.youtube.com/watch?v=E-u5j_Us8uI&safe=active

Page 41: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

2)2)PhospholipidsPhospholipids-- structure

1 hydrophilic head

2 hydrophobic tails

Page 42: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

2)2)PhospholipidsPhospholipids-- structure

1 hydrophilic head

2 hydrophobic tails

Page 43: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

3)3) Steroids Steroids--

4 Fused (connected) “rings”

cholesterol, testosterone, estrogen

Page 44: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

4) 4) WaxWax--

Long CH2 chain

Page 45: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.
Page 46: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Macromolecules (large molecules):

CarbohydratesCarbohydratesLipidsProteinsNucleic Acids

Page 47: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Proteins-Monomer = amino acid

Polymer of amino acids = polypeptides-

Page 48: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Proteins-function depends on shape:

1)support

2)structure

3) enzymes

Page 49: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

AminoAmino AcidsAcids = = monomermonomer

20 types20 types

Page 50: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

AminoAmino Acids Acids

CC

RR

(VARIABLE)(VARIABLE)

HH

Carboxyl

COOH

amino group

NH2

20 types20 types

Page 51: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

AminoAmino AcidsAcids

CC

RR

HH

carboxylamino group

20 types20 types20 varying 20 varying moleculesmolecules

Page 52: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Proteins-- precise sequence of amino acids.

amino - - carboxyl group group

Page 53: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Sequence of amino Sequence of amino acids determines acids determines HOW the protein HOW the protein

worksworks

Page 54: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Shape Shape determinedetermines how the s how the protein protein worksworks

Page 55: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Macromolecules (large molecules):

CarbohydratesCarbohydratesLipidsProteinsNucleic Acids

Page 56: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Nucleic Acids-

DNA

RNA

Programs ALL organism function

Page 57: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

Nucleic Acids-

Composed of: nitrogen base, sugar,

phosphate group

= NUCLEOTIDE

Page 58: Biochemistry. Macromolecules (large molecules):  Carbohydrates  Lipids  Proteins  Nucleic Acids These are Polymers ( many parts) constructed of Monomers.

DNA RNA