Bimonthly Meeting on Sep. 26, 2008 MRS on Exam 4465 Amarjeet Bhullar.
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Transcript of Bimonthly Meeting on Sep. 26, 2008 MRS on Exam 4465 Amarjeet Bhullar.
Bimonthly Meeting on Sep. 26, 2008
MRS on Exam 4465
Amarjeet Bhullar
We have compared metabolite ratios, calculated using three different methods:
• Directly Generated by Functool
• Metabolites Concentration Generated by
Functool
• Gaussian Function Overlapped on metabolite peak
S19.6
Exam ID: 4465June 23, 2008
Patient Name:
AD
Chemical Information on S9.6
50 100 150 200 2500
140
280
420
560
Sig
nal
(M
R U
nit
s)
Voxel # 16
Image Number
Real Spectrum
50 100 150 200 250-200
-100
0
100
Sign
al (
MR
Uni
ts)
Voxel # 20
Real Spectrum
Image Number
50 100 150 200 250-300
0
300
600
Image Number
Sig
nal
(M
R U
nit
s)
Voxel # 23
Real Spectrum
50 100 150 200 250
-400
-200
0
200
400
600
Image Number
Sig
nal
(MR
Un
its)
Real Spectrum
Voxel # 24
Chemical Information on S9.6
50 100 150 200 250-150
0
150
300
450
Sig
nal
Number of Image
Real Spectrum
Voxel # 25
50 100 150 200 250-200
0
200
400
600Voxel # 26
Sig
nal
(M
R U
nit
s)
Image Number
50 100 150 200 250
-200
0
200
400
600
Sig
nal
(M
R U
nit
s)
Image Number
Real Data
Voxel # 27
50 100 150 200 250
0
150
300
450
Sig
nal
(M
R U
nit
s)
Image Number
Real Spectrum
Voxel # 30
Chemical Information on S9.6
50 100 150 200 250-300
-200
-100
0
100
Real Spectrum
Voxel # 31
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
-100
0
100
200
300
400Voxel # 32
Real Spectrum
Image Number
Sig
nal
(M
R U
nit
s)
50 100 150 200 250-100
0
100
200
300
400
500
Real Spectrum
Voxel # 33
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
200
400
Sig
nal
Image Number
Real Spectrum
Voxel # 34
Chemical Information on S19.6
50 100 150 200 2500
500
1000
1500
2000
Sig
nal
(M
R U
nit
s)
Image Number
Real Spectrum
Voxel # 16, S19.6
50 100 150 200 250-800
-600
-400
-200
0
200
400
Sig
nal
(M
R U
nit
s)
Image Number
Real Spectrum
Voxel # 17, S19.6
50 100 150 200 250
0
200
400
600
800
1000
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 19, S19.6
50 100 150 200 250
-200
0
200
400
600
800Voxel # 23, S19.6
Real SpectrumS
ign
al (
MR
Un
its)
Image Number
Chemical Information on S19.6
50 100 150 200 250-800
-600
-400
-200
0
200
400
Voxel # 24, S19.6
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
400
800
1200Voxel # 25, S19.6
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
50 100 150 200 2500
200
400
600
800
1000
1200
1400
Real Spectrum
Voxel # 26, S19.6
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
-200
0
200
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 27, S19.6
Real Spectrum
Chemical Information on S19.6
50 100 150 200 2500
200
400
600
800
1000
1200
Real Spectrum
Voxel # 30, S19.6
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
200
400
600
800
1000Voxel # 31, S19.6
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
50 100 150 200 2500
400
800
1200Voxel # 32, S19.6
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
400
800
1200Voxel # 33, S19.6
Sig
nal
(M
R U
nit
s)
Image Number
Real Spectrum
Chemical Information on S19.6
50 100 150 200 250
0
200
400
600Voxel # 34, S19.6
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
50 100 150 200 250-600
-400
-200
0
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 39, S19.6
50 100 150 200 2500
200
400
600
800
1000
1200
Real Spectrum
Voxel # 38, S19.6
Sig
nal
(M
R U
nit
s)
Image Number
Chemical Information on I0.4
50 100 150 200 2500
300
600
900 Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 16, I0.4
50 100 150 200 250
0
200
400
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 19, I0.4
50 100 150 200 250
0
200
400
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 20, I0.4
50 100 150 200 250
-600
-400
-200
0
200
Real SpectrumSig
nal
(M
R U
nit
s)
Image Number
Voxel # 24, I0.4
Chemical Information on I0.4
50 100 150 200 2500
300
600
900
1200Voxel # 25, I0.4
Real Spectrum
Sign
al (
MR
Uni
ts)
Image Number50 100 150 200 250
0
300
600
900
1200
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 26, I0.4
50 100 150 200 250
-200
0
200
400
600
Real Spectrum
Voxel # 27, I0.4
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
300
600
900
1200
Real SpectrumS
ign
al (
MR
Un
its)
Image Number
Voxel # 30, I0.4
Chemical Information on I0.4
50 100 150 200 250-800
-600
-400
-200
0
Voxel # 31, I0.4
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
200
400
600
800
1000
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 32, I0.4
50 100 150 200 2500
300
600
900
1200Voxel # 33, I0.4
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number50 100 150 200 250
0
300
600
900
1200
Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 34, I0.4
Chemical Information on I0.4
50 100 150 200 2500
500
1000
1500
Sig
nal
(M
R U
nit
s)
Image Number
Real Spectrum
Voxel # 37, I0.4
50 100 150 200 250-300
-200
-100
0
100
Real Spectrum
Image Number
Sig
nal
(M
R U
nit
s)
Voxel # 38, I0.4
50 100 150 200 250-100
0
100
200
300
400 Real Spectrum
Sig
nal
(M
R U
nit
s)
Image Number
Voxel # 40, I0.4
50 100 150 200 250
0
300
600
900
1200S
ign
al (
MR
Un
its)
Image Number
Voxel # 41, I0.4
Real Spectrum
0.6
0.8
1.0
1.2
1.4
1.6
1.8 F1 F2 Our Calculation
Cho
/Cre
Voxel #
S9.6
Metabolite Ratios Cho/Cre and Cho/NAA
0.0
0.4
0.8
1.2
1.6 F1 F2 Our Calculation
Voxel #C
ho/N
AA
S9.6
Metabolite Ratios Cho/Cre and Cho/NAA
0.0
0.5
1.0
1.5
2.0
2.5
3.0
Voxel #
Cho
/Cre
S19.6 F1 F2 Our Calculation
0.0
0.2
0.4
0.6
0.8
1.0 F1 F2 Our Calculation
S19.6
Voxel #C
ho/N
AA
Metabolite Ratios Cho/Cre and Cho/NAA
0.0
0.4
0.8
1.2
1.6
2.0
Voxel #
Cho
/Cre
F1 F2 Our Calculation
I0.4
0.0
0.2
0.4
0.6
0.8
1.0
F1 F2 Our Calculation
I0.4
Voxel #C
ho/N
AA
Conclusion:
There is no significant difference between our calculation and Functool.
Suggestions are welcome