BHS 499-07 Memory and Amnesia Neuroscience of Memory.
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Transcript of BHS 499-07 Memory and Amnesia Neuroscience of Memory.
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BHS 499-07Memory and Amnesia
Neuroscience of Memory
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Neurons
Memory consists of a change in the structure of neurons that leads to increased likelihood of firing.
Review of neural structure:• CD 2.1 first slide, 2.2 action potential
Long-term Potentiation (LTP) – both short and long-term changes in the brain• CD 13.2 & 13.3 (consolidation)
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A Blind Alley
McConnell (1962) – cut up planaria (flatworms) and fed them to other worms who showed the same learning.• McConnell thought memories were encoded
in the RNA, not just the neurons.
• By eating the RNA, the attributes were passed on to another being (or person).
His results were not replicated (not true).
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Larger Structures
Semantic memory is structured based on shared meaning, not prior associations.• Similar concepts in terms of meaning are
stored closer to each other.
• Semantic “closeness” is metaphoric, based on response times.
Activation spreads to related items. A great deal of repeated use moves
items from episodic to semantic memory.
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Influences on Memory
Alcohol – Bits & Pieces Stress -- Kolb & Whishaw Seg 32 (CD 2) Diabetes – Kolb & Whishaw Ch 13 Seg 6
(CD 3)
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