beta-Carotene€¦ · beta-Carotene This Smart Search PDF was created based on 1 research topic....

beta-Carotene

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Research Topicbeta-Carotene

This Smart Search PDF was created based on 1 research topic. There are a total of 53unique research articles on GreenMedInfo.com in regard to your search topic, all compiledin this research document.

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Associated with Your Search Topic57 Relevant Results forDiseases

Disease/SymptomCumulativeKnowledge

ArticleCount

Breast Cancer: Prevention 30 3

Breast Cancer 21 3

Bone Fractures 20 1

Cystic Fibrosis 20 2

Macular Degeneration 20 2

Pancreatic Cancer 20 1

Oxidative Stress 17 5

DNA damage 15 5

Liver Cancer: Prevention 14 3

Diabetes Mellitus: Type 2 12 2

Vitamin A Deficiency 12 2

Radiation Induced Illness 11 2

Bladder Cancer 10 1

Cataract 10 1

Common variable immunodeficiency (CVID) 10 1

Diabetes Insipidus 10 1

Diabetes Mellitus: Type 1 10 1

Diabetes Mellitus: Type 2: Prevention 10 1

Endometrial Cancer 10 1

Gastric Cancer 10 1

High Homocysteine 10 1

Insulin Resistance 10 1

Leukoplakia 10 1

Overweight 10 1

http://www.greenmedinfo.com/disease/breast-cancer-prevention

http://www.greenmedinfo.com/disease/breast-cancer

http://www.greenmedinfo.com/disease/bone-fractures

http://www.greenmedinfo.com/disease/cystic-fibrosis

http://www.greenmedinfo.com/disease/macular-degeneration

http://www.greenmedinfo.com/disease/pancreatic-cancer

http://www.greenmedinfo.com/disease/oxidative-stress

http://www.greenmedinfo.com/disease/dna-damage

http://www.greenmedinfo.com/disease/liver-cancer-prevention

http://www.greenmedinfo.com/disease/diabetes-mellitus-type-2

http://www.greenmedinfo.com/disease/vitamin-deficiency

http://www.greenmedinfo.com/disease/radiation-induced-illness

http://www.greenmedinfo.com/disease/bladder-cancer

http://www.greenmedinfo.com/disease/cataract

http://www.greenmedinfo.com/disease/common-variable-immunodeficiency-cvid

http://www.greenmedinfo.com/disease/diabetes-insipidus


http://www.greenmedinfo.com/disease/diabetes-mellitus-type-2-prevention

http://www.greenmedinfo.com/disease/endometrial-cancer

http://www.greenmedinfo.com/disease/gastric-cancer

http://www.greenmedinfo.com/disease/high-homocysteine

http://www.greenmedinfo.com/disease/insulin-resistance

http://www.greenmedinfo.com/disease/leukoplakia

http://www.greenmedinfo.com/disease/overweight

Periodontal Wound Healing 10 1

Periodontitis 10 1

Prostate Cancer: Prevention 10 1

Smoking 10 1

Thyroid Cancer 10 1

Vision Loss 10 1

Liver Cancer 4 3

Cancers: All 3 3

Drug Toxicity: Methotrexate 2 1

Drug-Induced Toxicity: Methotrexate 2 1

Leukemia 2 2

Lipid Peroxidation 2 2

Low Immune Function: Splenic Dysfunction 2 1

Lung Cancer: Prevention 2 1

Oral Cancer 2 1

Skin Cancer: Prevention 2 1

Skin Diseases: Photo-Aging 2 1

Squamous cell carcinoma 2 1

Stress 2 1

Tongue Cancer 2 1

Tracheal Cancer 2 1

Alzheimer's Disease 1 1

Cancer Stem Cells 1 1

Corticosteroid-Induced Toxicity 1 1

Hepatitis C 1 1

Immune Disorders: Low Immune Function 1 1

Iron Overload 1 1

Iron Poisoning 1 1

http://www.greenmedinfo.com/disease/periodontal-wound-healing

http://www.greenmedinfo.com/disease/periodontitis

http://www.greenmedinfo.com/disease/prostate-cancer-prevention

http://www.greenmedinfo.com/disease/smoking

http://www.greenmedinfo.com/disease/thyroid-cancer

http://www.greenmedinfo.com/disease/vision-loss

http://www.greenmedinfo.com/disease/liver-cancer

http://www.greenmedinfo.com/disease/cancers-all

http://www.greenmedinfo.com/disease/drug-toxicity-methotrexate

http://www.greenmedinfo.com/disease/drug-induced-toxicity-methotrexate

http://www.greenmedinfo.com/disease/leukemia

http://www.greenmedinfo.com/disease/lipid-peroxidation

http://www.greenmedinfo.com/disease/low-immune-function-splenic-dysfunction

http://www.greenmedinfo.com/disease/lung-cancer-prevention

http://www.greenmedinfo.com/disease/oral-cancer

http://www.greenmedinfo.com/disease/skin-cancer-prevention

http://www.greenmedinfo.com/disease/skin-diseases-photo-aging

http://www.greenmedinfo.com/disease/squamous-cell-carcinoma

http://www.greenmedinfo.com/disease/stress

http://www.greenmedinfo.com/disease/tongue-cancer

http://www.greenmedinfo.com/disease/tracheal-cancer

http://www.greenmedinfo.com/disease/alzheimers-disease

http://www.greenmedinfo.com/disease/cancer-stem-cells

http://www.greenmedinfo.com/disease/corticosteroid-induced-toxicity

http://www.greenmedinfo.com/disease/hepatitis-c

http://www.greenmedinfo.com/disease/immune-disorders-low-immune-function

http://www.greenmedinfo.com/disease/iron-overload

http://www.greenmedinfo.com/disease/iron-poisoning

Liver Cirrhosis 1 1

Neurodegenerative Diseases 1 1

Promyelocytic leukemia 1 1

Sickle Cell Anemia 1 1

Tumors 1 1

23 Relevant Results for Pharmacological Actions

Pharmacological Action NameCumulativeKnowledge

ArticleCount

Antioxidants 93 16

Chemopreventive 57 9

Anticarcinogenic Agents 16 5

Insulin Sensitizers 10 1

Antiproliferative 3 2

Apoptotic 3 3

Immunostimulatory 3 2

Catalase Up-Regulation 2 1

Cell cycle arrest 2 2

Gastroprotective 2 1

Genoprotective 2 2

Malondialdehyde Down-regulation 2 1

MicroRNA modulator 2 1

Superoxide Dismutase Up-regulation 2 1

Anti-Proliferative 1 1

Antimutagenic Agents 1 1

Chemosensitizer 1 1

Multidrug Resistance Gene Modulators 1 1

Neuroprotective Agents 1 1

Radioprotective 1 1

http://www.greenmedinfo.com/disease/liver-cirrhosis

http://www.greenmedinfo.com/disease/neurodegenerative-diseases

http://www.greenmedinfo.com/disease/promyelocytic-leukemia

http://www.greenmedinfo.com/disease/sickle-cell-anemia

http://www.greenmedinfo.com/disease/tumors

http://www.greenmedinfo.com/pharmacological-action/antioxidants

http://www.greenmedinfo.com/pharmacological-action/chemopreventive

http://www.greenmedinfo.com/pharmacological-action/anticarcinogenic-agents

http://www.greenmedinfo.com/pharmacological-action/insulin-sensitizers

http://www.greenmedinfo.com/pharmacological-action/antiproliferative

http://www.greenmedinfo.com/pharmacological-action/apoptotic

http://www.greenmedinfo.com/pharmacological-action/immunostimulatory

http://www.greenmedinfo.com/pharmacological-action/catalase-regulation

http://www.greenmedinfo.com/pharmacological-action/cell-cycle-arrest

http://www.greenmedinfo.com/pharmacological-action/gastroprotective

http://www.greenmedinfo.com/pharmacological-action/genoprotective

http://www.greenmedinfo.com/pharmacological-action/malondialdehyde-down-regulation

http://www.greenmedinfo.com/pharmacological-action/microrna-modulator

http://www.greenmedinfo.com/pharmacological-action/superoxide-dismutase-regulation

http://www.greenmedinfo.com/pharmacological-action/anti-proliferative

http://www.greenmedinfo.com/pharmacological-action/antimutagenic-agents

http://www.greenmedinfo.com/pharmacological-action/chemosensitizer

http://www.greenmedinfo.com/pharmacological-action/multidrug-resistance-gene-modulators

http://www.greenmedinfo.com/pharmacological-action/neuroprotective-agents

http://www.greenmedinfo.com/pharmacological-action/radioprotective

Radiosensitizer 1 1

Tumor Necrosis Factor (TNF) Alpha Inhibitor 1 1

Wnt/β-catenin pathway down-regulation 1 1

55 Relevant Results for Substances

Substance NameCumulativeKnowledge

ArticleCount

Vitamin C 97 14

Vitamin E 92 10

Carotenoids 82 16

Lycopene 62 8

Cryptoxanthin 40 3

Alpha-Carotene 32 4

Lutein 30 3

Selenium 30 2

Zeaxanthin 30 3

Vitamin A 29 6

Fruit: All 21 3

Vegetables: All 21 3

Antioxidant formulas 20 2

Watermelon 20 2

Linoleic acid 11 2

Vitamin D 11 2

Vitamin E: alpha tocopherol 11 2

DHA (Docosahexaenoic Acid) 10 1

EPA (Eicosapentaenoic Acid) 10 1

Fish 10 1

Folic Acid 10 1

Soup 10 1

http://www.greenmedinfo.com/pharmacological-action/radiosensitizer

http://www.greenmedinfo.com/pharmacological-action/tumor-necrosis-factor-tnf-alpha-inhibitor

http://www.greenmedinfo.com/pharmacological-action/wnt-catenin-pathway-down-regulation

http://www.greenmedinfo.com/substance/vitamin-c

http://www.greenmedinfo.com/substance/vitamin-e

http://www.greenmedinfo.com/substance/carotenoids

http://www.greenmedinfo.com/substance/lycopene

http://www.greenmedinfo.com/substance/cryptoxanthin

http://www.greenmedinfo.com/substance/alpha-carotene

http://www.greenmedinfo.com/substance/lutein

http://www.greenmedinfo.com/substance/selenium

http://www.greenmedinfo.com/substance/zeaxanthin

http://www.greenmedinfo.com/substance/vitamin

http://www.greenmedinfo.com/substance/fruit-all

http://www.greenmedinfo.com/substance/vegetables-all

http://www.greenmedinfo.com/substance/antioxidant-formulas

http://www.greenmedinfo.com/substance/watermelon

http://www.greenmedinfo.com/substance/linoleic-acid

http://www.greenmedinfo.com/substance/vitamin-d

http://www.greenmedinfo.com/substance/vitamin-e-alpha-tocopherol

http://www.greenmedinfo.com/substance/dha-docosahexaenoic-acid

http://www.greenmedinfo.com/substance/epa-eicosapentaenoic-acid

http://www.greenmedinfo.com/substance/fish

http://www.greenmedinfo.com/substance/folic-acid

http://www.greenmedinfo.com/substance/soup

Tomato 10 1

Vitamin B-12 10 1

Zinc 10 1

Curcumin 6 5

Astaxanthin 5 4

Achiote 2 1

Apricot 2 1

Cassava 2 1

EGCG (Epigallocatechin gallate) 2 2

Hesperidin 2 1

Melatonin 2 1

Piperine 2 2

Alpha-Lipoic Acid 1 1

Bitter Melon 1 1

Bixin 1 1

Black Tea 1 1

Canthaxanthin 1 1

Capsaicin 1 1

Capsanthin 1 1

Chlorogenic Acid 1 1

Fucoxanthin 1 1

Genistein 1 1

Gingerol 1 1

Grape Seed Extract 1 1

Green Tea 1 1

Indole-3-Carbinol 1 1

Inositol 1 1

Myo-inositol 1 1

http://www.greenmedinfo.com/substance/tomato

http://www.greenmedinfo.com/substance/vitamin-b-12

http://www.greenmedinfo.com/substance/zinc

http://www.greenmedinfo.com/substance/curcumin

http://www.greenmedinfo.com/substance/astaxanthin

http://www.greenmedinfo.com/substance/achiote

http://www.greenmedinfo.com/substance/apricot

http://www.greenmedinfo.com/substance/cassava

http://www.greenmedinfo.com/substance/egcg-epigallocatechin-gallate

http://www.greenmedinfo.com/substance/hesperidin

http://www.greenmedinfo.com/substance/melatonin

http://www.greenmedinfo.com/substance/piperine

http://www.greenmedinfo.com/substance/alpha-lipoic-acid

http://www.greenmedinfo.com/substance/bitter-melon

http://www.greenmedinfo.com/substance/bixin

http://www.greenmedinfo.com/substance/black-tea

http://www.greenmedinfo.com/substance/canthaxanthin

http://www.greenmedinfo.com/substance/capsaicin

http://www.greenmedinfo.com/substance/capsanthin

http://www.greenmedinfo.com/substance/chlorogenic-acid

http://www.greenmedinfo.com/substance/fucoxanthin

http://www.greenmedinfo.com/substance/genistein

http://www.greenmedinfo.com/substance/gingerol

http://www.greenmedinfo.com/substance/grape-seed-extract

http://www.greenmedinfo.com/substance/green-tea

http://www.greenmedinfo.com/substance/indole-3-carbinol

http://www.greenmedinfo.com/substance/inositol

http://www.greenmedinfo.com/substance/myo-inositol

Pycnogenol (Pine Bark) 1 1

Quercetin 1 1

Resveratrol 1 1

Sea buckthorn 1 1

Sulforaphane 1 1

14 Relevant Results for Keywords

Keyword NameCumulativeKnowledge

ArticleCount

Risk Reduction 50 4

Diseases that are Linked 12 2

Anti-Obesity Agents 10 1

Bioavailability 10 1

Dietary Modification 10 1

Raw versus Cooked 10 1

Telomere Length 10 1

Plant Extracts 6 3

Drug Resistance 1 1

Drug-Plant-Vitamin Synergies 1 1

Drug: Hydrocortisone 1 1

Multidrug Resistance 1 1

Natural Substance/Drug Synergy 1 1

Selective Cytotoxicity 1 1

1 Relevant Result for Problematic Actions

Problematic Action NameCumulativeKnowledge

ArticleCount

Microwave Cooking 10 1

1 Relevant Result for Therapeutic Actions

http://www.greenmedinfo.com/substance/pycnogenol-pine-bark

http://www.greenmedinfo.com/substance/quercetin

http://www.greenmedinfo.com/substance/resveratrol

http://www.greenmedinfo.com/substance/sea-buckthorn

http://www.greenmedinfo.com/substance/sulforaphane

http://www.greenmedinfo.com/keyword/risk-reduction

http://www.greenmedinfo.com/keyword/diseases-are-linked

http://www.greenmedinfo.com/keyword/anti-obesity-agents

http://www.greenmedinfo.com/keyword/bioavailability

http://www.greenmedinfo.com/keyword/dietary-modification

http://www.greenmedinfo.com/keyword/raw-versus-cooked

http://www.greenmedinfo.com/keyword/telomere-length

http://www.greenmedinfo.com/keyword/plant-extracts

http://www.greenmedinfo.com/keyword/drug-resistance

http://www.greenmedinfo.com/keyword/drug-plant-vitamin-synergies

http://www.greenmedinfo.com/keyword/drug-hydrocortisone

http://www.greenmedinfo.com/keyword/multidrug-resistance

http://www.greenmedinfo.com/keyword/natural-substancedrug-synergy

http://www.greenmedinfo.com/keyword/selective-cytotoxicity

http://www.greenmedinfo.com/anti-therapeutic-action/microwave-cooking

Therapeutic Action NameCumulativeKnowledge

ArticleCount

Fasting/Caloric Restriction 10 1

1 Relevant Result for Problem Substances

Problem Substance NameCumulativeKnowledge

ArticleCount

17beta-estradiol 10 1

View the Evidence. 53 Research Articles in Total.

Category : Diseases

Alzheimer's Disease (AC 1) (CK 1)

Vitamin A and beta-carotene have anti-Alzheimerpotential.Pubmed Data : J Alzheimers Dis. 2011 Aug 2. Epub 2011 Aug 2. PMID: 21811022

Article Published Date : Aug 02, 2011

Authors : Junichi Takasaki, Kenjiro Ono, Yuji Yoshiike, Mie Hirohata, Tokuhei Ikeda, AkiyoshiMorinaga, Akihiko Takashima, Masahito Yamada

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin A : CK(496) : AC(76)Diseases : Alzheimer's Disease : CK(1269) : AC(366) , Neurodegenerative Diseases : CK(3346) :AC(834)Pharmacological Actions : Neuroprotective Agents : CK(2214) : AC(1040)

http://www.greenmedinfo.com/therapeutic-action/fastingcaloric-restriction

http://www.greenmedinfo.com/toxic-ingredient/17beta-estradiol

http://www.ncbi.nlm.nih.gov/pubmed/21811022







Bladder Cancer (AC 1) (CK 10)

There is an increased risk of bladder cancer in smokerswith lower serum vitamin D.Pubmed Data : Biol Trace Elem Res. 2002 Nov;89(2):105-10. PMID: 20978193

Article Published Date : Nov 01, 2002

Authors : Alison M Mondul, Stephanie J Weinstein, Satu Männistö, Kirk Snyder, Ronald L Horst,Jarmo Virtamo, Demetrius Albanes

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin D : CK(3074) : AC(432)Diseases : Bladder Cancer : CK(318) : AC(97) , Smoking : CK(676) : AC(102)Therapeutic Actions : Fasting/Caloric Restriction : CK(307) : AC(64)

Bone Fractures (AC 1) (CK 20)

This meta-analysis suggests that blood retinol level is adouble-edged sword for risk of hip fracture.Pubmed Data : J Bone Miner Res. 2014 Sep ;29(9):2032-9. PMID: 24700407


Authors : Ai-Min Wu, Chao-Qun Huang, Zhong-Ke Lin, Nai-Feng Tian, Wen-Fei Ni, Xiang-YangWang, Hua-Zi Xu, Yong-Long Chi

Study Type : Meta AnalysisAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Vitamin A : CK(496) : AC(76)Diseases : Bone Fractures : CK(514) : AC(78)Additional Keywords : Bone Fractures : CK(514) : AC(78)












http://www.greenmedinfo.com/disease/bone-fractures

http://www.greenmedinfo.com/category/keywords/Risk Factors

Breast Cancer (AC 3) (CK 21)

In older women, β-carotene levels are independently andinversely associated with estradiol.Pubmed Data : Nutrients. 2015 Aug ;7(8):6506-19. Epub 2015 Aug 5. PMID: 26251919

Article Published Date : Jul 31, 2015

Authors : Marcello Maggio, Francesca de Vita, Fulvio Lauretani, Stefania Bandinelli, Richard DSemba, Benedetta Bartali, Antonio Cherubini, Anne R Cappola, Gian Paolo Ceda, Luigi Ferrucci

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Breast Cancer : CK(3488) : AC(1048)Additional Keywords : Breast Cancer : CK(3488) : AC(1048)Problem Substances : 17beta-estradiol : CK(38) : AC(7)

Lycopene and beta carotene inhibit cell proliferation,arrest the cell cycle in different phases and increaseapoptosis.Pubmed Data : Anticancer Res. 2014 Mar ;34(3):1377-86. PMID: 24596385

Article Published Date : Feb 28, 2014

Authors : Nathalie Fonseca Gloria, Nathalia Soares, Camila Brand, Felipe Leite Oliveira, RadovanBorojevic, Anderson Junger Teodoro

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Lycopene :CK(365) : AC(78)Diseases : Breast Cancer : CK(3488) : AC(1048)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509) , Antiproliferative :CK(2449) : AC(1663), Apoptotic : CK(2905) : AC(2037) , Cell cycle arrest : CK(802) : AC(604)

The results suggest a protective role of α-carotene, β-carotene, lycopene , lutein and zeaxanthin in breastcancer risk.Pubmed Data : Br J Nutr. 2015 Oct 20:1-9. Epub 2015 Oct 20. PMID: 26482064

Article Published Date : Oct 19, 2015

Authors : Bo Yan, Min-Shan Lu, Lian Wang, Xiong-Fei Mo, Wei-Ping Luo, Yu-Feng Du, Cai-Xia Zhang





http://www.greenmedinfo.com/category/keywords/Risk Factors

http://www.greenmedinfo.com/toxic-ingredient/17beta-estradiol













Study Type : Human StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300), Lutein : CK(225) : AC(37) , Lycopene : CK(365) : AC(78) , Zeaxanthin : CK(67) :AC(9)Diseases : Breast Cancer : CK(3488) : AC(1048)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Dietary Modification : CK(312) : AC(46) , Risk Reduction : CK(6055) : AC(650)

Breast Cancer: Prevention (AC 3) (CK30)

Breast cancer risk may be affected by telomere lengthamong premenopausal women or women with lowdietary intake of antioxidants or antioxidantsupplements.Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916

Article Published Date : Apr 01, 2009

Authors : Jing Shen, Marilie D Gammon, Mary Beth Terry, Qiao Wang, Patrick Bradshaw, Susan LTeitelbaum, Alfred I Neugut, Regina M Santella

Study Type : Human StudyAdditional LinksSubstances : Antioxidant formulas : CK(489) : AC(75) , beta-Carotene : CK(317) : AC(52) , Vitamin C :CK(1933) : AC(400), Vitamin E : CK(1656) : AC(290)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Telomere Length : CK(18) : AC(5)

Higher intake of lycopene, beta-carotene and beta-cryptoxanthin is associated to a lower risk of breastcancer among Chinese women.Pubmed Data : Asia Pac J Clin Nutr. 2007;16 Suppl 1:437-42. PMID: 17392146

Article Published Date : Jan 01, 2007

Authors : Jiang-ping Huang, Min Zhang, C D'Arcy J Holman, Xing Xie

Study Type : Human Study






















Additional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Cryptoxanthin :CK(70) : AC(13), Lycopene : CK(365) : AC(78)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509)Additional Keywords : Risk Reduction : CK(6065) : AC(651)

The consumption of alpha and beta-carotene reduces therisk of breast cancer development.Pubmed Data : Breast Cancer Res Treat. 2011 Sep 7. Epub 2011 Sep 7. PMID: 21901390

Article Published Date : Sep 07, 2011

Authors : Fulan Hu, Baina Wang Yi, Wencui Zhang, Jing Liang, Chunqing Lin, Dandan Li, Fan Wang,Da Pang, Yashuang Zhao

Study Type : Human StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(318) : AC(53)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)

Cancer Stem Cells (AC 1) (CK 1)

The use of phytochemicals may be a true therapeuticstrategy for eradicating cancer through the elimination ofCSCs.Pubmed Data : Int J Mol Sci. 2015 ;16(7):15727-42. Epub 2015 Jul 10. PMID: 26184171

Article Published Date : Dec 31, 2014

Authors : Emanuele-Salvatore Scarpa, Paolino Ninfali

Study Type : ReviewAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Curcumin : CK(4106) : AC(2161) , EGCG(Epigallocatechin gallate) : CK(598) : AC(307), Genistein : CK(515) : AC(228) , Piperine : CK(114) :AC(60), Sulforaphane : CK(533) : AC(262)Diseases : Cancer Stem Cells : CK(105) : AC(64) , Cancers: All : CK(14158) : AC(4474)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761) , Wnt/β-catenin pathway down-regulation : CK(48) : AC(26)Additional Keywords : Wnt/β-catenin pathway down-regulation : CK(48) : AC(26) , SelectiveCytotoxicity : CK(155) : AC(110)


























http://www.greenmedinfo.com/category/keywords/Drug resistance


Cancers: All (AC 3) (CK 3)

In this review, they have summarized the recent progresson dietary nutraceuticals in reversing multidrugresistance.Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):6831-9. PMID: 26514453


Authors : Muhammad Khan, Amara Maryam, Tahir Mehmood, Yaofang Zhang, Tonghui Ma

Study Type : ReviewAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Bitter Melon : CK(72) : AC(29) , Capsaicin : CK(129) :AC(55), Curcumin : CK(4106) : AC(2161) , EGCG (Epigallocatechin gallate) : CK(598) : AC(307) , Fruit:All : CK(3530) : AC(769), Fucoxanthin : CK(21) : AC(15), Gingerol : CK(53) : AC(31), Grape Seed Extract: CK(278) : AC(81), Indole-3-Carbinol : CK(41) : AC(27) , Piperine : CK(114) : AC(60) , Quercetin :CK(556) : AC(245), Resveratrol : CK(1221) : AC(735) , Vegetables: All : CK(1032) : AC(113)Diseases : Cancers: All : CK(14158) : AC(4474)Pharmacological Actions : Multidrug Resistance Gene Modulators : CK(20) : AC(15)Additional Keywords : Multidrug Resistance : CK(6) : AC(4) , Natural Substance/Drug Synergy :CK(337) : AC(138)







































Vitamin C (dehydroascorbic acid) and mixtures of vitaminE and beta-carotene possess antitumor properties uponradiation and increase the chemotherapeutic activity ofmitomycin C.Pubmed Data : In Vivo. 2004 Nov-Dec;18(6):795-8. PMID: 15646822


Authors : Cornelia Kammerer, Nikola Getoff

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Cancers: All : CK(14158) : AC(4474) , Tumors : CK(203) : AC(119)Pharmacological Actions : Chemosensitizer : CK(390) : AC(282) , Radiosensitizer : CK(96) : AC(60)Additional Keywords : Drug-Plant-Vitamin Synergies : CK(965) : AC(266)

Cataract (AC 1) (CK 10)

Daily use of vitamin E, Vitamin C, and beta-carotene forthree years produces a small deceleration in theprogression of age-related cataract.Pubmed Data : Arch Ophthalmol. 2001 Oct;119(10):1439-52. PMID: 11594943


Authors : [No authors listed]

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Cataract : CK(196) : AC(61)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)


















Common variable immunodeficiency(CVID) (AC 1) (CK 10)

Patients with common variable immunodeficiency haveenhanced oxidative stress and high homocysteine levelsassociated with deficiencies of basic vitamins isPubmed Data : Eur J Clin Invest. 1997 Sep;27(9):723-30. PMID: 9352241


Authors : P Aukrust, R K Berge, F Müller, P M Ueland, A M Svardal, S S Frøland

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Folic Acid : CK(643) : AC(93), Vitamin B-12 : CK(770) :AC(103), Vitamin E : CK(1656) : AC(290)Diseases : Common variable immunodeficiency (CVID) : CK(60) : AC(6), High Homocysteine :CK(431) : AC(63)Additional Keywords : Diseases that are Linked : CK(2275) : AC(298)

Corticosteroid-Induced Toxicity (AC 1)(CK 1)

Beta-carotene, curcumin, and ascorbic acid preventhydrocortisone-induced genotoxicity.Pubmed Data : Int J Radiat Oncol Biol Phys. 2002 Jan 1;52(1):212-23. PMID: 15586444


Authors : Md Sultan Ahmad, Sheeba, Mohd Afzal

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Curcumin : CK(4106) : AC(2161) , Vitamin C :CK(1933) : AC(400)Diseases : Corticosteroid-Induced Toxicity : CK(77) : AC(16) , DNA damage : CK(968) : AC(376)Pharmacological Actions : Antimutagenic Agents : CK(126) : AC(72) , Antioxidants : CK(7081) :



















AC(2591), Cell cycle arrest : CK(802) : AC(604) , Genoprotective : CK(257) : AC(93)Additional Keywords : Drug: Hydrocortisone : CK(1) : AC(1)

Cystic Fibrosis (AC 2) (CK 20)

Antioxidant supplementation may have therapeutic valuein the treatment of cystic fibrosis - Article 2.Pubmed Data : Am J Clin Nutr. 2003 Jan;77(1):150-9. PMID: 12499335


Authors : Lisa G Wood, Dominic A Fitzgerald, Alexander K Lee, Manohar L Garg

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Selenium : CK(784) : AC(139)Diseases : Cystic Fibrosis : CK(547) : AC(83)

Beta-carotene supplementation ameliorates deficienciesand reduces oxidative stress in Cystic Fibrosis patients.Pubmed Data : Ann Nutr Metab. 2000;44(1):30-7. PMID: 10838464


Authors : P Rust, I Eichler, S Renner, I Elmadfa

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Cystic Fibrosis : CK(547) : AC(83)Pharmacological Actions : Antioxidants : CK(7082) : AC(2592)

DNA damage (AC 5) (CK 15)

Ascorbic acid and β-carotene have an anti-cancer effectagainst a human hepatocellular carcinoma cell line.















Pubmed Data : Mol Biol Rep. 2011 Oct ;38(7):4265-72. Epub 2010 Nov 30. PMID: 21116852


Authors : Erkan Yurtcu, Ozlem Darcansoy Iseri, Feride I Sahin

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400)Diseases : DNA damage : CK(968) : AC(376) , Lipid Peroxidation : CK(661) : AC(243) , Liver Cancer :CK(1199) : AC(449)Pharmacological Actions : Apoptotic : CK(2905) : AC(2037)




Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Curcumin : CK(4106) : AC(2161) , Vitamin C :CK(1933) : AC(400)Diseases : Corticosteroid-Induced Toxicity : CK(77) : AC(16) , DNA damage : CK(968) : AC(376)Pharmacological Actions : Antimutagenic Agents : CK(126) : AC(72) , Antioxidants : CK(7081) :AC(2591), Cell cycle arrest : CK(802) : AC(604) , Genoprotective : CK(257) : AC(93)Additional Keywords : Drug: Hydrocortisone : CK(1) : AC(1)

Chlorogenic acid, curcumin and beta-carotene protectagainst gamma-radiation-induced in vivo chromosomaldamage.Pubmed Data : Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 7694126


Authors : S K Abraham, L Sarma, P C Kesavan

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Chlorogenic Acid :CK(13) : AC(7), Curcumin : CK(4106) : AC(2161)Diseases : DNA damage : CK(968) : AC(376) , Radiation Induced Illness : CK(1046) : AC(264)Pharmacological Actions : Genoprotective : CK(257) : AC(93) , Radioprotective : CK(725) : AC(258)

High combined intakes of vitamins C and E, beta-carotene, beta-cryptoxanthin, and lutein-zeaxanthin fromfood, or a diet high in their food sources, may protect































against cumulative DNA damage in ionizing radiationpersons.Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19793852


Authors : Lee C Yong, Martin R Petersen, Alice J Sigurdson, Laura A Sampson, Elizabeth M Ward

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Lutein : CK(225) :AC(37), Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) : AC(290) , Zeaxanthin : CK(67) : AC(9)Diseases : DNA damage : CK(967) : AC(375) , Radiation Induced Illness : CK(1046) : AC(264)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Vitamin A and beta-carotene may have a therapeutic rolein tracheal cancer through its DNA-repairing activity.Pubmed Data : J Chromatogr A. 1996 Jan 8;719(2):353-64. PMID: 7767911


Authors : A P Wolterbeek, R Roggeband, C J van Moorsel, R A Baan, J H Koeman, V J Feron, A ARutten

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Vitamin A :CK(496) : AC(76)Diseases : DNA damage : CK(968) : AC(376) , Tracheal Cancer : CK(4) : AC(2)Additional Keywords : Diseases that are Linked : CK(2275) : AC(298)

Diabetes Insipidus (AC 1) (CK 10)

Microwave cooking increases glucose, insulin and C-peptide responses and lowers satiety and beta carotenelevels versus raw ones.Pubmed Data : Int J Food Sci Nutr. 1995 Feb;46(1):3-12. PMID: 7712340


Authors : K Gustafsson, N G Asp, B Hagander, M Nyman, T Schweizer

Study Type : Human StudyAdditional Links





















Substances : beta-Carotene : CK(317) : AC(52)Diseases : Diabetes Insipidus : CK(35) : AC(5) , Diabetes Mellitus: Type 1 : CK(1064) : AC(282) ,Diabetes Mellitus: Type 2 : CK(3315) : AC(585) , Diabetes Mellitus: Type 2: Prevention : CK(634) :AC(81)Additional Keywords : Raw versus Cooked : CK(69) : AC(13)Anti Therapeutic Actions : Microwave Cooking : CK(49) : AC(28)

Diabetes Mellitus: Type 1 (AC 1) (CK10)




Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Diabetes Insipidus : CK(35) : AC(5) , Diabetes Mellitus: Type 1 : CK(1064) : AC(282) ,Diabetes Mellitus: Type 2 : CK(3315) : AC(585) , Diabetes Mellitus: Type 2: Prevention : CK(634) :AC(81)Additional Keywords : Raw versus Cooked : CK(69) : AC(13)Anti Therapeutic Actions : Microwave Cooking : CK(49) : AC(28)

Diabetes Mellitus: Type 2 (AC 2) (CK12)

Annatto extract and β-carotene enhances antioxidantstatus and regulate gene expression in neutrophils of


















diabetic rats.Pubmed Data : Free Radic Res. 2012 Mar ;46(3):329-38. Epub 2012 Feb 6. PMID: 22239725


Authors : Joamyr Victor Rossoni Júnior, Glaucy Rodrigues Araújo, Bruno Da Cruz Pádua, CíntiaLopes de Brito Magalhães, Míriam Martins Chaves, Maria Lúcia Pedrosa, Marcelo Eustáquio Silva,Daniela Caldeira Costa

Study Type : Animal StudyAdditional LinksSubstances : Achiote : CK(3) : AC(2) , beta-Carotene : CK(317) : AC(52)Diseases : Diabetes Mellitus: Type 2 : CK(3315) : AC(585) , Oxidative Stress : CK(3752) : AC(1342)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591) , Catalase Up-Regulation : CK(104) :AC(39), MicroRNA modulator : CK(252) : AC(136) , Superoxide Dismutase Up-regulation : CK(500) :AC(167)Additional Keywords : Superoxide Dismutase Up-regulation : CK(500) : AC(167) , Plant Extracts :CK(7211) : AC(2386)





Diabetes Mellitus: Type 2: Prevention(AC 1) (CK 10)

Microwave cooking increases glucose, insulin and C-










http://www.greenmedinfo.com/category/keywords/gene-expression-regulation











peptide responses and lowers satiety and beta carotenelevels versus raw ones.Pubmed Data : Int J Food Sci Nutr. 1995 Feb;46(1):3-12. PMID: 7712340




Drug Toxicity: Methotrexate (AC 1)(CK 2)

Apricot and beta-carotene have a potent protective effectagainst methotrexate-induced intestinal oxidativedamage in rats.Pubmed Data : Food Chem Toxicol. 2008 Sep;46(9):3015-22. Epub 2008 Jun 14. PMID: 18601970


Authors : Nigar Vardi, Hakan Parlakpinar, Feral Ozturk, Burhan Ates, Mehmet Gul, Asli Cetin, AliErdogan, Ali Otlu

Study Type : Animal StudyAdditional LinksSubstances : Apricot : CK(12) : AC(6) , beta-Carotene : CK(317) : AC(52)Diseases : Drug-Induced Toxicity: Methotrexate : CK(35) : AC(10) , Drug Toxicity: Methotrexate :CK(39) : AC(18), Oxidative Stress : CK(3753) : AC(1343)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)Additional Keywords : Plant Extracts : CK(7211) : AC(2386)



















Drug-Induced Toxicity: Methotrexate(AC 1) (CK 2)





Endometrial Cancer (AC 1) (CK 10)

Plasma levels of beta-carotene and lycopene are inverselyassociated with the risk of endometrial cancer in Koreanwomen.Pubmed Data : Acta Obstet Gynecol Scand. 2009;88(4):434-9. PMID: 19235557


Authors : Nan-Hee Jeong, Eun-Seop Song, Jong-Min Lee, Kwang-Beom Lee, Mi-Kyung Kim, Young-Mi Yun, Jae-Kwan Lee, Sung-Kyong Son, Jung-Pil Lee, Jae-Hoon Kim, Soo-Young Hur, Yong-Il Kwon

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Lycopene : CK(365) : AC(78)Diseases : Endometrial Cancer : CK(307) : AC(53)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)
















Gastric Cancer (AC 1) (CK 10)

Those with low levels of alpha-carotene and beta-carotene are at a higher risk of gastric cancer.Pubmed Data : Carcinogenesis. 2008 May;29(5):1042-8. Epub 2008 Mar 13. PMID: 18339681

Article Published Date : May 01, 2008

Authors : Christina Persson, Shizuka Sasazuki, Manami Inoue, Norie Kurahashi, Motoki Iwasaki,Tsutomu Miura, Weimin Ye, Shoichiro Tsugane,

Study Type : Human StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(318) : AC(53) , Carotenoids :CK(1593) : AC(300)Diseases : Gastric Cancer : CK(578) : AC(193)

Hepatitis C (AC 1) (CK 1)

Beta-caotene, vitamin D, linoleic acid possesses anti-hepatitis C virus activity in vitro.Pubmed Data : Antimicrob Agents Chemother. 2007 Jun;51(6):2016-27. Epub 2007 Apr 9. PMID:17420205

Article Published Date : Jun 01, 2007

Authors : Masahiko Yano, Masanori Ikeda, Ken-Ichi Abe, Hiromichi Dansako, Shogo Ohkoshi,Yutaka Aoyagi, Nobuyuki Kato

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Linoleic acid : CK(12) : AC(3) , Vitamin D : CK(3075) :AC(433)Diseases : Hepatitis C : CK(473) : AC(86)






http://www.greenmedinfo.com/disease/gastric-cancer






http://www.greenmedinfo.com/disease/hepatitis-c

High Homocysteine (AC 1) (CK 10)

Patients with common variable immunodeficiency haveenhanced oxidative stress and high homocysteine levelsassociated with deficiencies of basic vitamins isPubmed Data : Eur J Clin Invest. 1997 Sep;27(9):723-30. PMID: 9352241


Authors : P Aukrust, R K Berge, F Müller, P M Ueland, A M Svardal, S S Frøland

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Folic Acid : CK(643) : AC(93), Vitamin B-12 : CK(770) :AC(103), Vitamin E : CK(1656) : AC(290)Diseases : Common variable immunodeficiency (CVID) : CK(60) : AC(6), High Homocysteine :CK(431) : AC(63)Additional Keywords : Diseases that are Linked : CK(2275) : AC(298)

Immune Disorders: Low ImmuneFunction (AC 1) (CK 1)

Carotenoids such as beta-carotene, canthaxanthin andastaxanthin have possible immunomodulating activitiesto enhance the proliferation and functions of murineimmunocompetent cells.Pubmed Data : Int J Immunopharmacol. 1996 Dec;18(12):753-8. PMID: 9172019


Authors : Y Okai, K Higashi-Okai

Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Canthaxanthin :CK(4) : AC(3), Carotenoids : CK(1593) : AC(300)Diseases : Immune Disorders: Low Immune Function : CK(489) : AC(118)Pharmacological Actions : Antioxidants : CK(7082) : AC(2592) , Immunostimulatory : CK(260) :



















AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1696) : AC(626)

Insulin Resistance (AC 1) (CK 10)

Supplementation with fruit and vegetable juiceconcentrate was associated with an increase in serum β-carotene concentrations, reduction in adiposity and animprovement in insulin resistance.Pubmed Data : J Pediatr. 2012 Jul ;161(1):58-64.e1-2. Epub 2012 Feb 28. PMID: 22381025


Authors : Jose A Canas, Ligeia Damaso, Astrid Altomare, Kelleigh Killen, Jobayer Hossain,Prabhakaran Babu Balagopal

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Fruit: All : CK(3530) : AC(769) , Vegetables: All :CK(1032) : AC(113)Diseases : Insulin Resistance : CK(1652) : AC(338) , Overweight : CK(3157) : AC(521)Pharmacological Actions : Insulin Sensitizers : CK(347) : AC(68)Additional Keywords : Anti-Obesity Agents : CK(448) : AC(97) , Anti-Obesity Agents : CK(448) :AC(97), Anti-Obesity Agents : CK(448) : AC(97)

Iron Overload (AC 1) (CK 1)

Astaxanthin reduces iron-induced oxidative damage.Pubmed Data : Biochem Biophys Res Commun. 2001 Oct 19;288(1):225-32. PMID: 11594777


Authors : M P Barros, E Pinto, P Colepicolo, M Pedersén

Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300), Vitamin C : CK(1933) : AC(400)











http://www.greenmedinfo.com/category/keywords/Fruit Juice

http://www.greenmedinfo.com/category/keywords/Vegetable Juice







Diseases : Iron Overload : CK(31) : AC(17) , Iron Poisoning : CK(22) : AC(10) , Lipid Peroxidation :CK(661) : AC(243), Oxidative Stress : CK(3753) : AC(1343)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Iron Poisoning (AC 1) (CK 1)




Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300), Vitamin C : CK(1933) : AC(400)Diseases : Iron Overload : CK(31) : AC(17) , Iron Poisoning : CK(22) : AC(10) , Lipid Peroxidation :CK(661) : AC(243), Oxidative Stress : CK(3753) : AC(1343)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Leukemia (AC 2) (CK 2)

Beta-carotene induces apoptosis in leukemia cells.Pubmed Data : Int J Cancer. 2002 Feb 10;97(5):593-600. PMID: 11807783


Authors : Paola Palozza, Simona Serini, Angela Torsello, Alma Boninsegna, Valeria Covacci, NicolaMaggiano, Franco O Ranelletti, Federica I Wolf, Gabriella Calviello

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Leukemia : CK(947) : AC(373) , Promyelocytic leukemia : CK(98) : AC(83)Pharmacological Actions : Apoptotic : CK(2905) : AC(2037)























Carotenoids exhibit anti-leukemia activity.Pubmed Data : Arch Biochem Biophys. 2011 May 18. Epub 2011 May 18. PMID: 21620794


Authors : Xia Zhang, Wen-En Zhao, Liqiang Hu, Lei Zhao, Jinyong Huang

Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Bixin : CK(7) : AC(4) ,Capsanthin : CK(2) : AC(2) , Carotenoids : CK(1593) : AC(300)Diseases : Leukemia : CK(947) : AC(373)Pharmacological Actions : Anti-Proliferative : CK(59) : AC(52)

Leukoplakia (AC 1) (CK 10)

Beta-carotene has therapeutic value in the treatment ofleukoplakias.Pubmed Data : Arch Otolaryngol Head Neck Surg. 1999 Dec;125(12):1305-10. PMID: 10604407


Authors : H S Garewal, R V Katz, F Meyskens, J Pitcock, D Morse, S Friedman, Y Peng, D G Pendrys,S Mayne, D Alberts, T Kiersch, E Graver

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53)Diseases : Leukoplakia : CK(72) : AC(9)

Lipid Peroxidation (AC 2) (CK 2)

Ascorbic acid and β-carotene have an anti-cancer effectagainst a human hepatocellular carcinoma cell line.Pubmed Data : Mol Biol Rep. 2011 Oct ;38(7):4265-72. Epub 2010 Nov 30. PMID: 21116852














http://www.greenmedinfo.com/disease/leukoplakia









Liver Cancer (AC 3) (CK 4)

A combination of carotenoids and myo-inositol was foundto prevent hepatocellular carcinoma development inpatients with chronic viral hepatitis and cirrhosis.Pubmed Data : Nutr Cancer. 2009 ;61(6):789-91. PMID: 20155617


Authors : Hoyoku Nishino

Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Inositol : CK(74) :AC(10), Lycopene : CK(365) : AC(78) , Myo-inositol : CK(102) : AC(7)Diseases : Liver Cancer : CK(1199) : AC(449) , Liver Cirrhosis : CK(371) : AC(53)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509)

Ascorbic acid and β-carotene have an anti-cancer effect





























against a human hepatocellular carcinoma cell line.Pubmed Data : Mol Biol Rep. 2011 Oct ;38(7):4265-72. Epub 2010 Nov 30. PMID: 21116852




Vitamin A and beta-carotene exhibit an inhibitory effectduring 1,2-dimethylhydrazine inducedhepatocarcinogenesis.Pubmed Data : Food Chem Toxicol. 2007 Apr ;45(4):563-7. Epub 2006 Oct 10. PMID: 17113696


Authors : Alda R D Sampaio, Carlos E A Chagas, Thomas P Ong, Fernando S Moreno

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin A : CK(496) : AC(76)Diseases : Liver Cancer : CK(1199) : AC(449)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509) , Chemopreventive :CK(2665) : AC(761)

Liver Cancer: Prevention (AC 3) (CK14)

A diet rich in linoleic acid containing foods (e.g. whitemeats and fish) and beta-carotene was inversely relatedto HCC risk; iron intake was associated with increasedrisk.Pubmed Data : Eur J Cancer. 2007 Nov ;43(16):2381-7. Epub 2007 Aug 23. PMID: 17719221


















Authors : Jerry Polesel, Renato Talamini, Maurizio Montella, Luigino Dal Maso, Marina Crovatto,Maria Parpinel, Francesco Izzo, Luigi G Tommasi, Diego Serraino, Carlo La Vecchia, SilviaFranceschi

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Fish : CK(253) : AC(24) , Linoleic acid : CK(12) : AC(3)Diseases : Liver Cancer: Prevention : CK(182) : AC(37)

Beta-carotene and vitamin A inhibithepatocarcinogenesis.Pubmed Data : Nutr Cancer. 2002 ;44(1):80-8. PMID: 12672634


Authors : Fernando S Moreno, Ton S-Wu, Maria Margareth V Naves, Elaine R Silveira, SilviaCatarina Oloris, Maria Aparecida L da Costa, Maria Lúcia Z Dagli, Thomas Prates Ong

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin A : CK(496) : AC(76)Diseases : Liver Cancer: Prevention : CK(182) : AC(37)Pharmacological Actions : Antioxidants : CK(7082) : AC(2592) , Antiproliferative : CK(2449) :AC(1663), Chemopreventive : CK(2665) : AC(761)

These results suggest that not only beta-carotene, butalso other types of carotenoids, such as alpha-carotene,may play an important role in cancer prevention.Pubmed Data : Cancer Res. 1992 Dec 1 ;52(23):6583-7. PMID: 1423303


Authors : M Murakoshi, H Nishino, Y Satomi, J Takayasu, T Hasegawa, H Tokuda, A Iwashima, JOkuzumi, H Okabe, H Kitano

Study Type : Animal StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300)Diseases : Liver Cancer: Prevention : CK(182) : AC(37) , Lung Cancer: Prevention : CK(224) : AC(28) ,Skin Cancer: Prevention : CK(20) : AC(4)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509)

Liver Cirrhosis (AC 1) (CK 1)


http://www.greenmedinfo.com/substance/fish
























Low Immune Function: SplenicDysfunction (AC 1) (CK 2)

Dietary beta-carotene and astaxanthin but notcanthaxanthin stimulate splenocyte function in mice.Pubmed Data : Anticancer Res. 1999 Nov-Dec;19(6B):5223-7. PMID: 10697539


Authors : B P Chew, M W Wong, J S Park, T S Wong

Study Type : Animal StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(318) : AC(53)Diseases : Low Immune Function: Splenic Dysfunction : CK(13) : AC(7)Pharmacological Actions : Immunostimulatory : CK(260) : AC(57)

Lung Cancer: Prevention (AC 1) (CK 2)





















Macular Degeneration (AC 2) (CK 20)

Antioxidant supplements prevent oxidation ofcysteine/cystine redox in patients with age-relatedmacular degeneration.Pubmed Data : Am J Ophthalmol. 2005 Dec;140(6):1020-6. PMID: 16376645


Authors : Siobhan E Moriarty-Craige, Joanne Adkison, Michael Lynn, Gary Gensler, Susan Bressler,Dean P Jones, Paul Sternberg

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Macular Degeneration : CK(197) : AC(33)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Supplementation with vitamin C, E, beta-carontene andzinc demonstrates a statistically significant oddsreduction for the development of advanced age-related


















macular degeneration and vision loss.Pubmed Data : Arch Ophthalmol. 2001 Oct;119(10):1417-36. PMID: 11594942



Study Type : Human StudyAdditional LinksSubstances : Antioxidant formulas : CK(489) : AC(75) , beta-Carotene : CK(317) : AC(52) , Vitamin C :CK(1933) : AC(400), Vitamin E : CK(1656) : AC(290) , Zinc : CK(941) : AC(139)Diseases : Macular Degeneration : CK(197) : AC(33) , Vision Loss : CK(40) : AC(4)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Neurodegenerative Diseases (AC 1)(CK 1)





Oral Cancer (AC 1) (CK 2)

Curcumin, beta-carontein and hesperidin prevent


















chemically-induced oral cancer.Pubmed Data : Cancer Res. 1994 Sep 1;54(17):4653-9. PMID: 8062259


Authors : T Tanaka, H Makita, M Ohnishi, Y Hirose, A Wang, H Mori, K Satoh, A Hara, H Ogawa

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Curcumin :CK(4106) : AC(2161), Hesperidin : CK(196) : AC(53)Diseases : Oral Cancer : CK(193) : AC(77) , Squamous cell carcinoma : CK(152) : AC(67) , TongueCancer : CK(40) : AC(18)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)

Overweight (AC 1) (CK 10)





Oxidative Stress (AC 5) (CK 17)





















Annatto extract and β-carotene enhances antioxidantstatus and regulate gene expression in neutrophils ofdiabetic rats.Pubmed Data : Free Radic Res. 2012 Mar ;46(3):329-38. Epub 2012 Feb 6. PMID: 22239725











Study Type : In Vitro StudyAdditional Links
























Substances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300), Vitamin C : CK(1933) : AC(400)Diseases : Iron Overload : CK(31) : AC(17) , Iron Poisoning : CK(22) : AC(10) , Lipid Peroxidation :CK(661) : AC(243), Oxidative Stress : CK(3753) : AC(1343)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Beta-carotene protects against ozone induced skinoxidative stress which is consistent with its protectiverole on skin.Pubmed Data : Toxicol Ind Health. 2009 May;25(4-5):241-7. PMID: 19651793


Authors : G Valacchi, A Pecorelli, M Mencarelli, E Maioli, P A Davis

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Oxidative Stress : CK(3753) : AC(1343) , Skin Diseases: Photo-Aging : CK(122) : AC(50)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Fruit and vegetable soups contributed to increasing theconcentration of each carotenoid by more than 100%after 3 and 4 weeks of consumption.Pubmed Data : Eur J Nutr. 2012 Mar ;51(2):231-9. Epub 2011 Jun 7. PMID: 21647668


Authors : Rebeca Martínez-Tomás, Elvira Larqué, Daniel González-Silvera, María Sánchez-Campillo, María Isabel Burgos, Anna Wellner, Soledad Parra, Lucy Bialek, Marie Alminger,Francisca Pérez-Llamas

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Lycopene :CK(365) : AC(78), Soup : CK(20) : AC(2)Diseases : Oxidative Stress : CK(3753) : AC(1343)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)Additional Keywords : Bioavailability : CK(182) : AC(34)

Pancreatic Cancer (AC 1) (CK 20)

























Higher dietary intakes of selenium, vitamin C, vitamin E,β-carotene and β-cryptoxanthin were associated withreduced pancreatic cancer risk.Pubmed Data : Int J Food Sci Nutr. 2016 Jun 30:1-13. Epub 2016 Jun 30. PMID: 27356952


Authors : Jiamin Chen, Wuxia Jiang, Liming Shao, Dandan Zhong, Yihua Wu, Jianting Cai

Study Type : Meta AnalysisAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Cryptoxanthin : CK(70) : AC(13) , Selenium : CK(784) :AC(139), Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) : AC(290)Diseases : Pancreatic Cancer : CK(875) : AC(256)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)Additional Keywords : Risk Reduction : CK(6055) : AC(650)

Periodontal Wound Healing (AC 1) (CK10)

These findings may lead to the development of dietarystrategies to optimize healing after periodontalprocedures.Pubmed Data : J Nutr. 2015 Sep 30. Epub 2015 Sep 30. PMID: 26423734


Authors : David W Dodington, Peter C Fritz, Philip J Sullivan, Wendy E Ward

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , DHA (Docosahexaenoic Acid) : CK(783) : AC(129) ,EPA (Eicosapentaenoic Acid) : CK(758) : AC(105) , Fruit: All : CK(3530) : AC(769) , Vegetables: All :CK(1032) : AC(113), Vitamin C : CK(1933) : AC(400) , Vitamin E: alpha tocopherol : CK(1809) : AC(314)Diseases : Periodontal Wound Healing : CK(11) : AC(1) , Periodontitis : CK(161) : AC(38)






















Periodontitis (AC 1) (CK 10)

These findings may lead to the development of dietarystrategies to optimize healing after periodontalprocedures.Pubmed Data : J Nutr. 2015 Sep 30. Epub 2015 Sep 30. PMID: 26423734


Authors : David W Dodington, Peter C Fritz, Philip J Sullivan, Wendy E Ward

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , DHA (Docosahexaenoic Acid) : CK(783) : AC(129) ,EPA (Eicosapentaenoic Acid) : CK(758) : AC(105) , Fruit: All : CK(3530) : AC(769) , Vegetables: All :CK(1032) : AC(113), Vitamin C : CK(1933) : AC(400) , Vitamin E: alpha tocopherol : CK(1809) : AC(314)Diseases : Periodontal Wound Healing : CK(11) : AC(1) , Periodontitis : CK(161) : AC(38)

Promyelocytic leukemia (AC 1) (CK 1)




Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Leukemia : CK(947) : AC(373) , Promyelocytic leukemia : CK(98) : AC(83)Pharmacological Actions : Apoptotic : CK(2905) : AC(2037)


















Prostate Cancer: Prevention (AC 1)(CK 10)

Vegetables and fruits rich in lycopene and othercarotenoids may be protective against prostate cancer.Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967

Article Published Date : Mar 01, 2005

Authors : Le Jian, Chuan-Jun Du, Andy H Lee, Colin W Binns

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Cryptoxanthin :CK(70) : AC(13), Lutein : CK(225) : AC(37) , Lycopene : CK(365) : AC(78) , Tomato : CK(555) : AC(107) ,Watermelon : CK(48) : AC(9) , Zeaxanthin : CK(67) : AC(9)Diseases : Prostate Cancer: Prevention : CK(241) : AC(32)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Risk Reduction : CK(6065) : AC(651)

Radiation Induced Illness (AC 2) (CK11)




Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Chlorogenic Acid :CK(13) : AC(7), Curcumin : CK(4106) : AC(2161)Diseases : DNA damage : CK(968) : AC(376) , Radiation Induced Illness : CK(1046) : AC(264)






















Pharmacological Actions : Genoprotective : CK(257) : AC(93) , Radioprotective : CK(725) : AC(258)

High combined intakes of vitamins C and E, beta-carotene, beta-cryptoxanthin, and lutein-zeaxanthin fromfood, or a diet high in their food sources, may protectagainst cumulative DNA damage in ionizing radiationpersons.Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19793852




Sickle Cell Anemia (AC 1) (CK 1)

"Sickle cell anemia: a potential nutritional approach for amolecular disease."Pubmed Data : Nutrition. 2000 May ;16(5):330-8. PMID: 10793299


Authors : S T Ohnishi, T Ohnishi, G B Ogunmola

Study Type : ReviewAdditional LinksSubstances : Alpha-Lipoic Acid : CK(462) : AC(106) , beta-Carotene : CK(317) : AC(52) , Black Tea :CK(360) : AC(80), Green Tea : CK(1934) : AC(549) , Pycnogenol (Pine Bark) : CK(556) : AC(94) , VitaminC : CK(1933) : AC(400), Vitamin E : CK(1656) : AC(290)Diseases : Sickle Cell Anemia : CK(190) : AC(21)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

























Skin Cancer: Prevention (AC 1) (CK 2)





Skin Diseases: Photo-Aging (AC 1) (CK2)




















Smoking (AC 1) (CK 10)

There is an increased risk of bladder cancer in smokerswith lower serum vitamin D.Pubmed Data : Biol Trace Elem Res. 2002 Nov;89(2):105-10. PMID: 20978193


Authors : Alison M Mondul, Stephanie J Weinstein, Satu Männistö, Kirk Snyder, Ronald L Horst,Jarmo Virtamo, Demetrius Albanes

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin D : CK(3074) : AC(432)Diseases : Bladder Cancer : CK(318) : AC(97) , Smoking : CK(676) : AC(102)Therapeutic Actions : Fasting/Caloric Restriction : CK(307) : AC(64)

Squamous cell carcinoma (AC 1) (CK 2)

Curcumin, beta-carontein and hesperidin preventchemically-induced oral cancer.Pubmed Data : Cancer Res. 1994 Sep 1;54(17):4653-9. PMID: 8062259





















Stress (AC 1) (CK 2)

Melatonin, ascorbic acid and β-carotene could protectagainst gastric damage induced by intensive stress.Pubmed Data : Arch Med Sci. 2015 Oct 12 ;11(5):1129-36. PMID: 26528359


Authors : Aysin Akinci, Mukaddes Esrefoglu, Asli Cetin, Burhan Ates

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Melatonin : CK(937) : AC(296) , Vitamin C : CK(1933) :AC(400)Diseases : Stress : CK(607) : AC(99)Pharmacological Actions : Gastroprotective : CK(152) : AC(71) , Malondialdehyde Down-regulation: CK(474) : AC(131)

Thyroid Cancer (AC 1) (CK 10)

Beta-carotene, vitamin C and vitamin E deficiencies mayplay a role in the pathogenesis of thyroid cancer.Pubmed Data : Cancer. 1997 Jun 1;79(11):2186-92. PMID: 9179066


Authors : B D'Avanzo, E Ron, C La Vecchia, S Francaschi, E Negri, R Zleglar

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Thyroid Cancer : CK(220) : AC(51)














http://www.greenmedinfo.com/disease/thyroid-cancer

Tongue Cancer (AC 1) (CK 2)





Tracheal Cancer (AC 1) (CK 2)

Vitamin A and beta-carotene may have a therapeutic rolein tracheal cancer through its DNA-repairing activity.Pubmed Data : J Chromatogr A. 1996 Jan 8;719(2):353-64. PMID: 7767911


Authors : A P Wolterbeek, R Roggeband, C J van Moorsel, R A Baan, J H Koeman, V J Feron, A ARutten

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Vitamin A :CK(496) : AC(76)Diseases : DNA damage : CK(968) : AC(376) , Tracheal Cancer : CK(4) : AC(2)Additional Keywords : Diseases that are Linked : CK(2275) : AC(298)



















Tumors (AC 1) (CK 1)





Vision Loss (AC 1) (CK 10)

Supplementation with vitamin C, E, beta-carontene andzinc demonstrates a statistically significant oddsreduction for the development of advanced age-relatedmacular degeneration and vision loss.Pubmed Data : Arch Ophthalmol. 2001 Oct;119(10):1417-36. PMID: 11594942
























Vitamin A Deficiency (AC 2) (CK 12)

Beta-carotene from cassava leaves improves vitamin Astatus in rats.Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2007 Jul-Aug;146(1-2):235-40. Epub2006 Dec 15. PMID: 17261381

Article Published Date : Jul 01, 2007

Authors : Egle Machado de Almeida Siqueira, Sandra Fernandes Arruda, Rodrigo Martins deVargas, Elizabeth Maria Talá de Souza

Study Type : Animal StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Cassava : CK(7) : AC(4) , Vitamin A : CK(496) : AC(76)Diseases : Vitamin A Deficiency : CK(43) : AC(7)Additional Keywords : Plant Extracts : CK(7215) : AC(2388)

Consumption of watermelon juice increases plasmaconcentrations of lycopene and beta-carotene in humans.Pubmed Data : J Nutr. 2003 Apr;133(4):1043-50. PMID: 12672916


Authors : Alison J Edwards, Bryan T Vinyard, Eugene R Wiley, Ellen D Brown, Julie K Collins,Penelope Perkins-Veazie, Robert A Baker, Beverly A Clevidence

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Carotenoids : CK(1593) : AC(300) , Lycopene :CK(365) : AC(78), Watermelon : CK(48) : AC(9)Diseases : Vitamin A Deficiency : CK(43) : AC(7)

Category : Pharmacological Actions

Anti-Proliferative (AC 1) (CK 1)




http://www.greenmedinfo.com/substance/cassava











Carotenoids exhibit anti-leukemia activity.Pubmed Data : Arch Biochem Biophys. 2011 May 18. Epub 2011 May 18. PMID: 21620794


Authors : Xia Zhang, Wen-En Zhao, Liqiang Hu, Lei Zhao, Jinyong Huang

Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Bixin : CK(7) : AC(4) ,Capsanthin : CK(2) : AC(2) , Carotenoids : CK(1593) : AC(300)Diseases : Leukemia : CK(947) : AC(373)Pharmacological Actions : Anti-Proliferative : CK(59) : AC(52)

Anticarcinogenic Agents (AC 5) (CK 16)





Higher intake of lycopene, beta-carotene and beta-cryptoxanthin is associated to a lower risk of breastcancer among Chinese women.Pubmed Data : Asia Pac J Clin Nutr. 2007;16 Suppl 1:437-42. PMID: 17392146


Authors : Jiang-ping Huang, Min Zhang, C D'Arcy J Holman, Xing Xie

Study Type : Human StudyAdditional Links






















Substances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Cryptoxanthin :CK(70) : AC(13), Lycopene : CK(365) : AC(78)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Anticarcinogenic Agents : CK(1061) : AC(509)Additional Keywords : Risk Reduction : CK(6065) : AC(651)









Vitamin A and beta-carotene exhibit an inhibitory effectduring 1,2-dimethylhydrazine inducedhepatocarcinogenesis.




























Pubmed Data : Food Chem Toxicol. 2007 Apr ;45(4):563-7. Epub 2006 Oct 10. PMID: 17113696




Antimutagenic Agents (AC 1) (CK 1)





Antioxidants (AC 16) (CK 93)

"Sickle cell anemia: a potential nutritional approach for amolecular disease."Pubmed Data : Nutrition. 2000 May ;16(5):330-8. PMID: 10793299






















Authors : S T Ohnishi, T Ohnishi, G B Ogunmola

Study Type : ReviewAdditional LinksSubstances : Alpha-Lipoic Acid : CK(462) : AC(106) , beta-Carotene : CK(317) : AC(52) , Black Tea :CK(360) : AC(80), Green Tea : CK(1934) : AC(549) , Pycnogenol (Pine Bark) : CK(556) : AC(94) , VitaminC : CK(1933) : AC(400), Vitamin E : CK(1656) : AC(290)Diseases : Sickle Cell Anemia : CK(190) : AC(21)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)





Antioxidant supplements prevent oxidation ofcysteine/cystine redox in patients with age-relatedmacular degeneration.Pubmed Data : Am J Ophthalmol. 2005 Dec;140(6):1020-6. PMID: 16376645


Authors : Siobhan E Moriarty-Craige, Joanne Adkison, Michael Lynn, Gary Gensler, Susan Bressler,Dean P Jones, Paul Sternberg

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Macular Degeneration : CK(197) : AC(33)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

































Beta-carotene supplementation ameliorates deficienciesand reduces oxidative stress in Cystic Fibrosis patients.Pubmed Data : Ann Nutr Metab. 2000;44(1):30-7. PMID: 10838464


Authors : P Rust, I Eichler, S Renner, I Elmadfa

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)Diseases : Cystic Fibrosis : CK(547) : AC(83)Pharmacological Actions : Antioxidants : CK(7082) : AC(2592)





Carotenoids such as beta-carotene, canthaxanthin and
























astaxanthin have possible immunomodulating activitiesto enhance the proliferation and functions of murineimmunocompetent cells.Pubmed Data : Int J Immunopharmacol. 1996 Dec;18(12):753-8. PMID: 9172019



Study Type : In Vitro StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(317) : AC(52) , Canthaxanthin :CK(4) : AC(3), Carotenoids : CK(1593) : AC(300)Diseases : Immune Disorders: Low Immune Function : CK(489) : AC(118)Pharmacological Actions : Antioxidants : CK(7082) : AC(2592) , Immunostimulatory : CK(260) :AC(57), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1696) : AC(626)

Daily use of vitamin E, Vitamin C, and beta-carotene forthree years produces a small deceleration in theprogression of age-related cataract.Pubmed Data : Arch Ophthalmol. 2001 Oct;119(10):1439-52. PMID: 11594943



Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) :AC(290)Diseases : Cataract : CK(196) : AC(61)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)

Fruit and vegetable soups contributed to increasing theconcentration of each carotenoid by more than 100%after 3 and 4 weeks of consumption.Pubmed Data : Eur J Nutr. 2012 Mar ;51(2):231-9. Epub 2011 Jun 7. PMID: 21647668


Authors : Rebeca Martínez-Tomás, Elvira Larqué, Daniel González-Silvera, María Sánchez-Campillo, María Isabel Burgos, Anna Wellner, Soledad Parra, Lucy Bialek, Marie Alminger,Francisca Pérez-Llamas

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Lycopene :CK(365) : AC(78), Soup : CK(20) : AC(2)Diseases : Oxidative Stress : CK(3753) : AC(1343)

























Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)Additional Keywords : Bioavailability : CK(182) : AC(34)

High combined intakes of vitamins C and E, beta-carotene, beta-cryptoxanthin, and lutein-zeaxanthin fromfood, or a diet high in their food sources, may protectagainst cumulative DNA damage in ionizing radiationpersons.Pubmed Data : Am J Clin Nutr. 2009 Nov;90(5):1402-10. Epub 2009 Sep 30. PMID: 19793852




Higher dietary intakes of selenium, vitamin C, vitamin E,β-carotene and β-cryptoxanthin were associated withreduced pancreatic cancer risk.Pubmed Data : Int J Food Sci Nutr. 2016 Jun 30:1-13. Epub 2016 Jun 30. PMID: 27356952


Authors : Jiamin Chen, Wuxia Jiang, Liming Shao, Dandan Zhong, Yihua Wu, Jianting Cai

Study Type : Meta AnalysisAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Cryptoxanthin : CK(70) : AC(13) , Selenium : CK(784) :AC(139), Vitamin C : CK(1933) : AC(400) , Vitamin E : CK(1656) : AC(290)Diseases : Pancreatic Cancer : CK(875) : AC(256)Pharmacological Actions : Antioxidants : CK(7081) : AC(2591)Additional Keywords : Risk Reduction : CK(6055) : AC(650)

Sea buckthorn shoots and buds could be a good dietarysource of natural α-tocopherol and β-carotene.Pubmed Data : Saudi J Biol Sci. 2016 Jul ;23(4):512-6. Epub 2015 Jun 6. PMID: 27298585


Authors : Paweł Górnaś, Elga Šnē, Aleksander Siger, Dalija Segliņa

Study Type : Plant Study


























Additional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Sea buckthorn : CK(55) : AC(13) , Vitamin E: alphatocopherol : CK(1809) : AC(314)Pharmacological Actions : Antioxidants : CK(7103) : AC(2599)

Supplementation with vitamin C, E, beta-carontene andzinc demonstrates a statistically significant oddsreduction for the development of advanced age-relatedmacular degeneration and vision loss.Pubmed Data : Arch Ophthalmol. 2001 Oct;119(10):1417-36. PMID: 11594942




Antiproliferative (AC 2) (CK 3)





Lycopene and beta carotene inhibit cell proliferation,


http://www.greenmedinfo.com/substance/sea-buckthorn





















arrest the cell cycle in different phases and increaseapoptosis.Pubmed Data : Anticancer Res. 2014 Mar ;34(3):1377-86. PMID: 24596385




Apoptotic (AC 3) (CK 3)

Ascorbic acid and β-carotene have an anti-cancer effectagainst a human hepatocellular carcinoma cell line.Pubmed Data : Mol Biol Rep. 2011 Oct ;38(7):4265-72. Epub 2010 Nov 30. PMID: 21116852







Study Type : In Vitro StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52)






















Diseases : Leukemia : CK(947) : AC(373) , Promyelocytic leukemia : CK(98) : AC(83)Pharmacological Actions : Apoptotic : CK(2905) : AC(2037)





Catalase Up-Regulation (AC 1) (CK 2)






























Cell cycle arrest (AC 2) (CK 2)































Chemopreventive (AC 9) (CK 57)





Breast cancer risk may be affected by telomere lengthamong premenopausal women or women with lowdietary intake of antioxidants or antioxidantsupplements.Pubmed Data : Int J Cancer. 2009 Apr 1;124(7):1637-43. PMID: 19089916


Authors : Jing Shen, Marilie D Gammon, Mary Beth Terry, Qiao Wang, Patrick Bradshaw, Susan LTeitelbaum, Alfred I Neugut, Regina M Santella

Study Type : Human StudyAdditional LinksSubstances : Antioxidant formulas : CK(489) : AC(75) , beta-Carotene : CK(317) : AC(52) , Vitamin C :CK(1933) : AC(400), Vitamin E : CK(1656) : AC(290)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Telomere Length : CK(18) : AC(5)
























Plasma levels of beta-carotene and lycopene are inverselyassociated with the risk of endometrial cancer in Koreanwomen.Pubmed Data : Acta Obstet Gynecol Scand. 2009;88(4):434-9. PMID: 19235557


Authors : Nan-Hee Jeong, Eun-Seop Song, Jong-Min Lee, Kwang-Beom Lee, Mi-Kyung Kim, Young-Mi Yun, Jae-Kwan Lee, Sung-Kyong Son, Jung-Pil Lee, Jae-Hoon Kim, Soo-Young Hur, Yong-Il Kwon

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(318) : AC(53) , Lycopene : CK(365) : AC(78)Diseases : Endometrial Cancer : CK(307) : AC(53)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)

The consumption of alpha and beta-carotene reduces therisk of breast cancer development.Pubmed Data : Breast Cancer Res Treat. 2011 Sep 7. Epub 2011 Sep 7. PMID: 21901390


Authors : Fulan Hu, Baina Wang Yi, Wencui Zhang, Jing Liang, Chunqing Lin, Dandan Li, Fan Wang,Da Pang, Yashuang Zhao

Study Type : Human StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(318) : AC(53)Diseases : Breast Cancer: Prevention : CK(552) : AC(82)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)

The results suggest a protective role of α-carotene, β-carotene, lycopene , lutein and zeaxanthin in breastcancer risk.Pubmed Data : Br J Nutr. 2015 Oct 20:1-9. Epub 2015 Oct 20. PMID: 26482064


Authors : Bo Yan, Min-Shan Lu, Lian Wang, Xiong-Fei Mo, Wei-Ping Luo, Yu-Feng Du, Cai-Xia Zhang























Study Type : Human StudyAdditional LinksSubstances : Alpha-Carotene : CK(30) : AC(3) , beta-Carotene : CK(317) : AC(52) , Carotenoids :CK(1593) : AC(300), Lutein : CK(225) : AC(37) , Lycopene : CK(365) : AC(78) , Zeaxanthin : CK(67) :AC(9)Diseases : Breast Cancer : CK(3488) : AC(1048)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Dietary Modification : CK(312) : AC(46) , Risk Reduction : CK(6055) : AC(650)





Vegetables and fruits rich in lycopene and othercarotenoids may be protective against prostate cancer.Pubmed Data : Int J Cancer. 2005 Mar 1;113(6):1010-4. PMID: 15514967

Article Published Date : Mar 01, 2005

Authors : Le Jian, Chuan-Jun Du, Andy H Lee, Colin W Binns

Study Type : Human StudyAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Carotenoids : CK(1593) : AC(300) , Cryptoxanthin :CK(70) : AC(13), Lutein : CK(225) : AC(37) , Lycopene : CK(365) : AC(78) , Tomato : CK(555) : AC(107) ,Watermelon : CK(48) : AC(9) , Zeaxanthin : CK(67) : AC(9)Diseases : Prostate Cancer: Prevention : CK(241) : AC(32)Pharmacological Actions : Chemopreventive : CK(2665) : AC(761)Additional Keywords : Risk Reduction : CK(6065) : AC(651)

Vitamin A and beta-carotene exhibit an inhibitory effect






































during 1,2-dimethylhydrazine inducedhepatocarcinogenesis.Pubmed Data : Food Chem Toxicol. 2007 Apr ;45(4):563-7. Epub 2006 Oct 10. PMID: 17113696




Chemosensitizer (AC 1) (CK 1)





Gastroprotective (AC 1) (CK 2)


















Gastroprotective (AC 1) (CK 2)





Genoprotective (AC 2) (CK 2)





Chlorogenic acid, curcumin and beta-carotene protectagainst gamma-radiation-induced in vivo chromosomaldamage.






















Pubmed Data : Lipids Health Dis. 2009;8:39. Epub 2009 Oct 5. PMID: 7694126




Immunostimulatory (AC 2) (CK 3)





Dietary beta-carotene and astaxanthin but notcanthaxanthin stimulate splenocyte function in mice.Pubmed Data : Anticancer Res. 1999 Nov-Dec;19(6B):5223-7. PMID: 10697539


Authors : B P Chew, M W Wong, J S Park, T S Wong

Study Type : Animal StudyAdditional LinksSubstances : Astaxanthin : CK(406) : AC(146) , beta-Carotene : CK(318) : AC(53)Diseases : Low Immune Function: Splenic Dysfunction : CK(13) : AC(7)

























Pharmacological Actions : Immunostimulatory : CK(260) : AC(57)

Insulin Sensitizers (AC 1) (CK 10)





Malondialdehyde Down-regulation(AC 1) (CK 2)



















MicroRNA modulator (AC 1) (CK 2)





Multidrug Resistance GeneModulators (AC 1) (CK 1)

In this review, they have summarized the recent progress



















on dietary nutraceuticals in reversing multidrugresistance.Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(16):6831-9. PMID: 26514453


Authors : Muhammad Khan, Amara Maryam, Tahir Mehmood, Yaofang Zhang, Tonghui Ma

Study Type : ReviewAdditional LinksSubstances : beta-Carotene : CK(317) : AC(52) , Bitter Melon : CK(72) : AC(29) , Capsaicin : CK(129) :AC(55), Curcumin : CK(4106) : AC(2161) , EGCG (Epigallocatechin gallate) : CK(598) : AC(307) , Fruit:All : CK(3530) : AC(769), Fucoxanthin : CK(21) : AC(15), Gingerol : CK(53) : AC(31), Grape Seed Extract: CK(278) : AC(81), Indole-3-Carbinol : CK(41) : AC(27) , Piperine : CK(114) : AC(60) , Quercetin :CK(556) : AC(245), Resveratrol : CK(1221) : AC(735) , Vegetables: All : CK(1032) : AC(113)Diseases : Cancers: All : CK(14158) : AC(4474)Pharmacological Actions : Multidrug Resistance Gene Modulators : CK(20) : AC(15)Additional Keywords : Multidrug Resistance : CK(6) : AC(4) , Natural Substance/Drug Synergy :CK(337) : AC(138)

Neuroprotective Agents (AC 1) (CK 1)
































Radioprotective (AC 1) (CK 1)





Radiosensitizer (AC 1) (CK 1)

























Superoxide Dismutase Up-regulation(AC 1) (CK 2)





Tumor Necrosis Factor (TNF) AlphaInhibitor (AC 1) (CK 1)



















Wnt/β-catenin pathway down-regulation (AC 1) (CK 1)





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