Basic of Pre-excitation syndrome
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Transcript of Basic of Pre-excitation syndrome
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LEONARDO PASKAH SUCIADI, MDC A R D I O LO GY & VA S C U L A R M E D I C I N E - U N I V E R S I TA S PA D J A D J A R A N
B A N D U N G - I N D O N E S I A
PRE-EXCITATION SYNDROME
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DEFINITION
Short PR interval + usually with abnormal QRS complex
Almost congenital pathologic processRelated to the presence of accessory
pathways in cardiac conduction systemClinically related to paroxysmal
tacchyarrhythmia events + symptomsCommonest known: Wolff-Parkinson-White
(WPW) syndrome and Lown-Ganong-Levine (LGL) syndrome
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Normal Cardiac Conduction System
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ACCESSORY PATHWAYS (AccP)
AccP is congenitally abnormal pathway connecting A-V
Varies in : connecting circuits: atrioventricular (Kent’s bundle);
Mahaim fibers (atriofascicular/Brecenmacher tract, nodoventricular, fasciculoventricular); atriohisian (James’s fiber)
direction: anterograde, retrogade, bothThe characteristics of AccP compared to AV nodal
conduction; FASTER conduction velocity LONGER refractory period (in sinus rhythm)
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K = bundle of Kent; J = bundle of James; M = Mahaim fibres.The hatched area represents the atrioventricular border
Simplified representation of the various possible accessory conduction pathways
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EPIDEMIOLOGY
WPW syndrome is the commonest (1.5/1000); LGL syndrome is rareMan > womanUsually with ‘healthy heart’; Multiple right sided AccP
are common in Ebstein’s anomalyThe commonest presenting symptoms are related to
tacchyarrhythmia events (palpitation, presyncope, syncope, chest discomfort, dyspnea)
The commonest type of tacchyarrhythmias= AVRT (80%) frequency of PSVT is increased with age (10/100 in 20-40 yo VS 36/100 in >60 yo)
In patients with history of recurrent tacchyarrhythmia, prognosis is still good; SCD is only 0.1% (rare)
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Atrio-Ventricular Re-entry Tacchycardia (AVRT)
AccP is the component of a closed circuit = macro-reentry
Rapid tacchycardia with ventricular beats 150-250 bpm (faster than AVNRT); can be with narrow or widened complex QRS
Based on pathophysiology and ECG changes Orthodromic and antidromic AVRT
Sudden in onset and termination (paroxysmal)
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MECHANISM (in WPW syndrome)
Chou’s 6th ECG book
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ECG CHANGES
WPW ECG pattern (Chou’s) 1. PR interval <0.12 s with a normal P wave2. QRS complex >0.11 s3. initial slurring of the QRS complex (delta wave)4. secondary ST segmen and T wave changes
LGL ECG pattern shortened PR interval without abN width or form of QRS complex
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WPW ECG Type (Harold L.Brook’s ECG book)
Type A (more common) Kent’s fiber to LV criteria; WPW patterns with tall R waves in
leads V1 and V2Type B (much less common; more common in
Ebstein’s anomaly) Kent’s fiber to RV criteria; WPW patterns with predominantly
negative R waves and delta waves in V1 and V2, or deep QS waves in V1 and V2 anteroseptal pseudoinfarct
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Type A or B ?
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Type A or B ?
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LGL ECG pattern
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MANAGEMENT
Asymptomatic patients no further FU or th/Th/ :
Cathetherization RFA definite th/ Pharmacologic agents: decreasing conduction time and/or prolonging
refractory period to AV node and/or AccP recommendation; agents IA, IC, III. Verapamil is also considerable symptoms control
During paroxysmal AVRT according ACLS (haemodynamically stable/instable? Narrow/wide QRS complex)
Precaution in AVRT; Digitalis, verapamil IV, cathecolamines reduce refractory period of
AccP in Afib, these agents could lead to VF In pts with SVT, it is wise to carry out ECG recording after rhythm
conversion to recognize any preexisting pre-excitation pattern
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THANK YOU