Bader Traumatic Brain Injury Thurs 900 am...Theories on Brain Compartment 80% brain 10% blood 10%...

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11/26/2014 1 Neuro PROTECTion in Severe Traumatic Brain Injury Presented by: Mary Kay Bader RN, MSN CCNS, CNRN, CCRN, SCRN, FAHA, FNCS Neuro/Critical Care CNS Mission Hospital [email protected] Disclosures Bader Honorarium Bard, Neuroptics, & The Medicines Company AANN: Immediate Past President NCS Board of Directors Stock Options: Neuroptics Medical Advisory Board Brain Trauma Foundation Neuroptics PROTECT - ION P P = Physiologic Changes from TBI R = Resuscitation O = Operative Intervention T T = Technology E = Entry to ICU C = Coordinated Care/Clinical Guidelines T = Teamwork & Family Centered Care Traumatic Brain Injury Pathophysiology and Management Classification Pathological Mechanisms Direct Indirect Mechanism of Injury Blunt Falls MVAs Struck by object Penetrating -90% die Compression Blast Classification by Age Group - Mechanism http://www.cdc.gov/mmwr/preview/mmwrhtml/figures/s6005a1f5.gif

Transcript of Bader Traumatic Brain Injury Thurs 900 am...Theories on Brain Compartment 80% brain 10% blood 10%...

Page 1: Bader Traumatic Brain Injury Thurs 900 am...Theories on Brain Compartment 80% brain 10% blood 10% CSF If one increases the other two decrease Compensatory mechanisms SDH 80% 1 0 %

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Neuro PROTECTion in Severe Traumatic Brain Injury

Presented by:

Mary Kay Bader RN, MSN

CCNS, CNRN, CCRN, SCRN, FAHA, FNCS

Neuro/Critical Care CNS

Mission Hospital

[email protected]

Disclosures

� Bader� Honorarium

� Bard, Neuroptics, & The Medicines Company

� AANN: Immediate Past President

� NCS Board of Directors

� Stock Options: Neuroptics

� Medical Advisory Board� Brain Trauma Foundation

� Neuroptics

PROTECT - ION

�� P P = Physiologic Changes from TBI

��RR = Resuscitation

��OO = Operative Intervention

��T T = Technology

�� EE = Entry to ICU

�� CC = Coordinated Care/Clinical Guidelines

��TT = Teamwork & Family Centered Care

Traumatic Brain Injury

Pathophysiology and Management

Classification

� Pathological Mechanisms� Direct � Indirect

� Mechanism of Injury� Blunt

� Falls� MVAs� Struck by object

� Penetrating -90% die

� Compression� Blast

Classification by Age Group - Mechanism

http://www.cdc.gov/mmwr/preview/mmwrhtml/figures/s6005a1f5.gif

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Classification of Head Injury:Presentation

Primary Head Injury

� Occurs at the time of injury� Compromised skull integrity

� tearing of vessels/sinuses� dural tears� brain contusions� cranial nerve injuries

� Compromised brain integrity� linear and rotational forces

� Prevention is paramount to alter primary injury

PPhysiology Changes in Brain Injury

� Primary Injury

� Skull integrity� Fractures

� Basilar

� Depressed’

� Linear

Primary Injury: Epidural Hematoma

PPhysiology Changes in Brain Injury

� Primary Injury

� Subdural hematoma

�Focal injuries

�Diffuse injuries

Cerebral Contusions

� Types:� Fracture

� Coup

� Countercoup

� Herniation

� Surface

� Gliding (focal hemorrhage in cortex/subjacent white matter found in DIA

� Frequently frontal or temporal regions

� Vasogenic edema and central necrosis

� Diagnosis: CT and Exam

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Diffuse Axonal Injury

� Extensive disruption of axons/white matter in both hemispheres

� Stress of gray-white interface

� Petechial hemorrhages

� Axonal shearing/swelling

� Diagnosis: CT and exam

Primary Head Injury

� Results of compromised brain integrity and cellular changes� cerebral edema

� hemorrhage/hematomas

� herniation

� brain death

Secondary Injury: Alteration in CBF

� Numerous studies have found low CBF in early hours after TBI

� Martin et al study on CBF in TBI� 1st 12 to 24 hours: Hypoperfusion/decrease in CBF

� 24 hours to Day 5: CBF exceeding CMRO2

� Days 5/6 to 14: Slow flow due to vasospasm

� CBF altered but it must be balanced with metabolism and oxygenation

PPhysiology Changes in Brain Injury

Secondary Injury

�Extracranial causes�Hypotension�Hypocapnia and Hypercapnia�Hypoxia�Anemia�Acidosis�Hyperglycemia�Hyperthermia

Cerebral Blood FlowAutoregulation

�Vasomotor control�Intact: Increase in CPP causes

vasoconstriction and decrease in ICP�Vasomotor reactivity failure: Increase

in CPP causes vasodilation and inc ICP

�Flow metabolism�↑ metabolism ↑ CBF

�Metabolic substances�PaO2�PaCO2�pH i.e., acidosis = vasodilatation

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PPhysiologic Changes:Intracranial Pressure

� Theories on Brain Compartment� 80% brain

� 10% blood

� 10% CSF

� If one increases the other two decrease

� Compensatory mechanisms

SDH

80%10%

10%

Brain moves over

CSF shunts to spine SAS

Venous blood to heart

Symptoms of Increased ICP: Adults

� Early� Altered level of consciousness, restless,

agitated, headache, nausea, and contralateral motor weakness

� cranial nerves III and VI

� Late� Coma, vomiting, contralateral hemiplegia,

and posturing

� Alteration in Vital Signs

� Impaired brainstem reflexes� Pupils, dysconjugate gaze

RResuscitation

Arrival: Emergency Department Trauma Bay

Assess A-B-C: Oxygenation and Ventilation

Airway: Secured with RSI

Breathing: Connect to Ventilator

Avoid hyperventilation

Use Capnography to monitor ET CO2

Assess Circulation: Pulse, ECG and BP

�Hypertonic Saline� Posturing� Fixed non-reactive pupil

�Fluid Resuscitation� IV fluids to maintain adequate MAP 80

mm Hg

�Arterial line/Foley/OG

RResuscitationSevere TBI Patient: GCS 3-8 CT+ Injury

Arrival: Emergency Department Trauma Bay

RResuscitationSevere Brain Injury Algorithm

� CT scan

� OR Priorities

� Vent:100% FIO2 and PaCO2 35-45

� Place PA catheter; PbtO2; ICP

� Optimize MAP > 90 mm Hg� Fluids

� Correct coagulopathies

� Propofol to reduce CMRO2/ICP

OOperative Intervention

� Operative Intervention as indicated� Removal of SDH/EDH

� Craniectomy

� Placement of monitors

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OOperative InterventionSevere TBI Patient: GCS 3-8 CT+ Injury

OOperative InterventionSevere TBI Patient: GCS 3-8 CT+ Injury

TTechnology

� Technology� Place ICP monitor

� Treat for ICP > 20 mm Hg

� Clinicians should use a combination of ICP, clinical and brain CT finding to guide treatment

� Consider placement of PbtO2 monitor and treat PbtO2 < 15 mm Hg

� Place Hemodynamic Monitors and Regulate CPP 50-70 mm Hg

TechnologyIntracranial Pressure

� Normal range � 0-15 mm Hg

� Abnormal ranges� moderate 20-40

� severe > 40

Technology Oxygenation

Delivery of oxygen to the brain dependent on Lungs

Hemoglobin and PlasmaPreload (CVP) /Cardiac Output/ Afterload

(SVR)CBF = CPP/CVR

Autoregulation

Vasomotor control

Flow Metabolism↑metabolism/flow ↓metabolism/flow

Chemical

PaCO2 / PaO2 / pH

TTechnologyOxygen Dynamics:

Brain Tissue Oxygen Monitoring

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TTechnologyBrain Tissue Oxygen(Pbt02)

� Normal: 20-40 mm Hg

� Risk of death increases� < 15 mm Hg for 30 minutes

� < 10 mm Hg for 10 minutes

� PbtO2 < 5 mm Hg � high mortality

� PbtO2 < 2mm Hg - neuronal death

TTechnologyBrain Tissue Oxygen(Pbt02)

� Decreasing PbtO2� Hypoxia

� Low Hemoglobin

� Decreasing PaCO2

� Increased ICP

� Decreased MAP/CPP

� Shivering

� Vasospasm

� Systemic Causes� Pulmonary

� Cardiac/Hemodynamic

� Increasing PbtO2� Increasing FIO2 when

PaO2 < 80 mm Hg

� Increasing Hemoglobin

� Increasing PaCO2

� Draining CSF

� Increasing CPP/MAP

� Control shivering

� Barbiturates

Outcomes: TBI

41 pts (1998-2000) vs 139 (2000-

2005)

CPP & PbtO2

EEntry into the ICU

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CCoordinated CCare BTF: Core TBI Management

� Place ICP and cerebral ischemia monitor

� Core interventions� Drain CSF

� CO2 35-45 mm Hg

� Sedation/Analgesia

� Normothermia T 37

� CPP 50-70 mm Hg

BTF 2007 Severe TBI Guidelines

� BP & Oxygenation

� Hyperosmolar Tx

� Prophylactic Hypothermia

� DVT Prophylaxis

� Indications for ICP Monitoring

� ICP Monitoring Technology

� ICP Thresholds

� CPP Thresholds

� Brain Oxygen Monitoring &Thresholds

� Anesthetics, Analgesics, & Sedatives

� Nutrition

� Anti-Seizure

� Hyperventilation

� Steroids

CCoordinated CCare/CClinical Guidelines

Intensive Care Unit

A & B: Oxygenation/Ventilation Optimization Target PaCO2: 35 mm Hg (Day 1) & 30-35 (Days2-5)

Circulation: Maintain CPP 50-60 mm Hg as initial target

Autoregulation Testing: Intact – may need CPP to 70 mm Hg

Mannitol/Hypertonic Saline

ICP Management:

Draining CSF and Providing Sedation/Analgesia

Normothermia

CCoordinated CCare CClinical Guidelines

� Tertiary Interventions� Mild Hypothermia

� Decompressive Hemicraniectomy

� Barbiturate Coma� Not used much in US

TTeamworkPutting It All Together

Real World Real Patients

TTeamworkFamily Focused Care

� The healthcare team can impact patients outcome by actively engaging families in care: Family Focused Care

� Providing FFC requires assessment, planning, intervention, and evaluations for each unique family� Assurance, Proximity to Patient,

Information, Comfort and Support

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Teamwork: MD Protocols

Teamwork: MD Protocols

TTeamworkPrimary Interventions: Airway

� Assessment of Oxygenation/Ventilation� Patency of airway� Intervene: Rapid Sequence Intubation

� Oxygenation� Ventilation

� 1st 24 hours: PaCO2 35-45 mm Hg� If…Increased ICP PaCO2 30-35 mm Hg

� Influence of Airway/Ventilation

Issues Day 1� Pulmonary worsens

with PaO2 131 to 54� PbtO2 24 drops to 11

mm Hg

� ICP ↑35 mm Hg

– Low PbtO2 correlating with low PaO2

– Leads to Inc ICP

PbtO2 8 mm Hg

TTeamworkPrimary Interventions:

Circulation� Optimize CPP: Find the

right place

� Goal 50-70 mm Hg � Fluids: SVV < 13%

� Vasopressor support once euvolemic

Interventions: Circulation

�Neck midline

�Head of Bed�Flat if hypovolemic –

temporary measure

�30 degrees if euvolemic

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TTeamworkPrimary

Intervention: Intracranial

PressureCSF Drainage

� Normal range

� 0-15 mm Hg

� Abnormal ranges

� > 20 mm Hg

� Compliance waveform analysis

TTeamworkPrimary Intervention: Optimal

Sedation /Analgesia

� Analgesia� Fentanyl

� Sedation� Propofol

� Benzodiazepines

� Dexmedetomidine

TTeamworkPrimary

Intervention

Normothermia

&

Shivering

Step-Wise Managementof Shivering

TTeamworkSecondary/Tertiary

Interventions

� Secondary Interventions� HTS

� Mannitol

� Tertiary Interventions� Pentobarb coma

� Decompressive hemicraniectomy

� Mild Hypothermia

Interventions: Systemic

� Bundles� Infection prevention

� Ventilator� Foley� Central Line

� GI: �OG for gastric decompression�Stress ulcer prophylaxis�Nutrition: caloric goal by day3

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Interventions: Mobility

� Musculoskeletal� Early Mobility Program

START HERE

MOVEN SCREEN � Perform initial mobility

screen within 8 hrs of ICU

admission AND reassess

every 12 hours

� Report at MDR daily (RN,

RT, PT)

� Refer to the following

criteria in determining

mobility level:

M: Myocardial stability

• 50 < HR* < 120

• 90 < SBP* < 200

• 55 < MAP* < 120

*or normal range for pt

• No active ischemia x 24 hrs

• No new IV antidysrhythmic

agents x 24 hrs

O: Oxygenation

• FiO2 ≤ 60%

• PEEP < 12

• SPO2 ≥ 92% (88% with

activity)

• 10 < RR < 35

V: Vasopressor(s) minimal

• No increase in vasopressor

infusion in last 2 hrs

E: Engages to voice

• Pt opens eyes to verbal

stimulation

N: Neurologic stability

• ICP <20mmHg

• Absence of active seizures x

24hrs

CONTRAINDICATIONS:

• Unstable fx

• Active bleeding

• Active fluid resuscitation

• Open chest/abdomen

Includes complex, intubated, hemodynamically unstable and

stable intubated patients; may include non-intubated.

Includes intubated, non-intubated and hemodynamically

stable/stabilizing, no contraindications.

LEVEL I LEVEL II LEVEL III LEVEL IV LEVEL V

RASS -5 TO -3 RASS -3 AND UP RASS -1 AND UP RASS 0 AND UP RASS 0 AND UP

Goal: Passive ROM;

Initiate nutrition within

24 hrs

Goal: Upright sitting;

Increased strength;

Move arms against

gravity

Goal: Increased trunk

strength; Move legs against

gravity and readiness to

weight bear; Ability to

perform some ADL’s with

assist

Goal: Stand with assist;

March in place and

transfer to chair

Goal: Increase

ambulation distance

Activity:

• HOB ≥ 30o

• Passive ROM 3x/day

by RN, PCT or family

• Turn Q 2hr

• Cycle ergometry (as

determined by PT)

Consults:

• Dietician Consult

• PT Consult for cycle

ergometry and family education board

recommendations

• ST Consult for coma

stim and family

education board recommendations

Begin Family Education

Board

Activity:

• Full chair position 3x/day x 30 min

• Passive ROM

3x/day by RN, PCT

or family

• Turn Q 2hr

• Cycle ergometry (as determined by PT)

Consults:

• PT Consult if not

already following

• OT Consult PRN

(i.e., neuro, splinting

needs)

• SP Consult if pt has trach

Activity:

• Self or assisted turning Q 2hr

• Sitting EOB with RN, PT,

OT x 15 min

• Full chair position

3x/day x 45-60 min

• Begin transfer to chair via Sabina lift

• Passive ROM/begin to

encourage AAROM

3x/day by RN, PCT or

family

• Cycle ergometry (as

determined by PT)

Consults:

• OT Consult

• SP Consult if extubated

and not already

following

ARU Consult (if consistently

participating with therapy and

able to follow commands)

Activity:

• Active transfer OOB to chair with RN, PT, OT

3x/day x 30 min (meal time)

• Sitting on EOB/stand

at bedside with RN,

PT, OT

• Self or assisted

turning Q 2hr

• Full chair position

3x/day x 60 min

• Encourage

AAROM/AROM

3x/day with RN, PCT,

PT, OT or family

• Cycle ergometry (as

determined by PT)

Consults:

• ARU Consult

Activity:

• OOB to chair 3x/day with RN,

PCT, PT, OT x 60 min

• Ambulate

progressively

longer distances 2-

3x/day with RN, PCT, PT, OT

• Cycle ergometry

(as determined by

PT)

*For each position/activity change, allow 5-10 min for equilibration before determining the patient is intolerant.

**If the patient is intolerant of current activity level, reassess and place in appropriate mobility level.

MDR: Multidisciplinary Rounds EOB: Edge of Bed

PROM: Passive Range of Motion AAROM: Active-Assisted Range of Motion

AROM: Active Range of Motion ADL’s: Activities of Daily Living

Tolerates Level I activities, progress

to Level II.

Tolerates Level II

activities, progress

to Level III

Tolerates Level III

activities, progress

to Level IV.

Tolerates Level IV

activities, progress to Level V.

Guidelines for Early Mobility

• Levels

– Levels I-II-III• Complex, intubated, hemodynamically unstable and stable

intubated patients

• May include non-intubated

– Levels III-IV-V• Intubated, non-intubated and hemodynamically

stable/stabilizing, no contraindications.

• For each position/activity change, allow 5-10 min for equilibration before determining the patient is intolerant.

• If the patient is intolerant of current activity level, reassess and place in appropriate mobility level.

stable intubated patients; may include non

LEVEL I

RASS -5 TO -3

Goal: Passive ROM;

Initiate nutrition within

24 hrs

Activity:

• HOB ≥ 30o

• Passive ROM 3x/day

by RN, PCT or family

• Turn Q 2hr

• Cycle ergometry (as

determined by PT)

Consults:

• Dietician Consult

• PT Consult for cycle

ergometry and family

education board

recommendations

• ST Consult for coma

stim and family

education board

recommendations

Begin Family Education

Board

*For each position/activity change, allow 5

Tolerates Level I

activities, progress

to Level II.

Level I• RASS -5 to -3

Level II• RASS -3 and UP

stable intubated patients; may include non-intubated

LEVEL II

RASS -3 AND UP

Goal: Upright sitting;

Increased strength;

Move arms against

gravity

Activity:

• Full chair position

3x/day x 30 min

• Passive ROM

3x/day by RN, PCT

or family

• Turn Q 2hr

• Cycle ergometry (as

determined by PT)

Consults:

• PT Consult if not

already following

• OT Consult PRN

(i.e., neuro, splinting

needs)

• SP Consult if pt has

trach

Tolerates Level II

activities, progress

to Level III

Level III

• RASS -1 and UP

intubated. stable/stabilizing, no contraindications

LEVEL III

RASS -1 AND UP

Goal: Increased trunk

strength; Move legs against

gravity and readiness to

weight bear; Ability to

perform some ADL’s with

assist

Activity:

• Self or assisted turning

Q 2hr

• Sitting EOB with RN, PT,

OT x 15 min

• Full chair position

3x/day x 45-60 min

• Begin transfer to chair

via Sabina lift

• Passive ROM/begin to

encourage AAROM

3x/day by RN, PCT or

family

• Cycle ergometry (as

determined by PT)

Consults:

• OT Consult

• SP Consult if extubated

and not already

following

ARU Consult (if consistently

participating with therapy and

able to follow commands)

10 min for equilibration before determining the patient is intolerant.

Tolerates Level III

activities, progress

to Level IV.

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Levels IV and V• RASS 0 and UP

stable/stabilizing, no contraindications.

LEVEL IV LEVEL V

RASS 0 AND UP RASS 0 AND UP

Goal: Stand with assist;

March in place and

transfer to chair

Goal: Increase

ambulation distance

Activity:

• Active transfer OOB to

chair with RN, PT, OT

3x/day x 30 min (meal

time)

• Sitting on EOB/stand

at bedside with RN,

PT, OT

• Self or assisted

turning Q 2hr

• Full chair position

3x/day x 60 min

• Encourage

AAROM/AROM

3x/day with RN, PCT,

PT, OT or family

• Cycle ergometry (as

determined by PT)

Consults:

• ARU Consult

Activity:

• OOB to chair

3x/day with RN,

PCT, PT, OT x 60

min

• Ambulate

progressively

longer distances 2-

3x/day with RN,

PCT, PT, OT

• Cycle ergometry

(as determined by

PT)

Tolerates Level IV

activities, progress to Level V.

Nursing Strategies for Neuro

PROTECT - ION�� P P = Physiologic Changes from TBI

�� RR = Resuscitation

�� OO = Operative Intervention

�� T T = Technology

�� EE = Entry to ICU

�� CC = Coordinated Care/Clinical Guidelines

�� TT = Teamwork & Family Centered Care

�� I I – Individualize Care!

��O O – Outcomes must be measured and analyzed!

��NN – Nuances: What have you learned as a team?

Individualize Care� Each patient is unique!

� Responses to injury vary

Outcome Measurement in TBI

Case Study

Case Overview

� 30 year old male involved in altercation falls backwards/strikes head

� Arrival in ED as a Trauma� GCS 3 with fixed non-reactive pupils at

5 mm bilateral

� Intubated with 7.5 ET/Foley/OG

� IV � Mannitol 100 grams IV

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CT

4/6/19834/6/1983

Page: 13 of 217Page: 13 of 217

Acq No: 2Acq No: 2KVp: 120KVp: 120mA: 223mA: 223Tilt: -8Tilt: -8RD: 217RD: 217

BRAIN WO STBRAIN WO ST

11/15/2013 6:52:37 PM 11/15/2013 6:52:37 PM

C T20131115-0111C T20131115-0111

LOC : 1717.30LOC : 1717.30

C ompressed 11:1Compressed 11:1

Jakishev, Amirzhan AJakishev, Amirzhan A

AR01001691AR01001691

4/6/19834/6/1983

Page: 14 of 217Page: 14 of 217

Acq No: 2Acq No: 2KVp: 120KVp: 120mA: 218mA: 218Tilt: -8Tilt: -8RD: 217RD: 217

MIssion AS64 MIssion AS64

CT Brain Head wo ContrastCT Brain Head wo Contrast

BRAIN WO STBRAIN WO ST

11/15/2013 6:52:37 PM 11/15/2013 6:52:37 PM

CT20131115-0111CT20131115-0111

LOC: 1722.30LOC: 1722.30

Compressed 11:1Compressed 11:1

AAAR01001691AR01001691

4/6/19834/6/1983

Acq No: 2Acq No: 2KVp: 120KVp: 120mA: 206mA: 206

RD: 217RD: 217

C T Brain Head wo C ontrastC T Brain Head wo Contrast

BRAIN WO STBRAIN WO ST

11/15/2013 6:52:38 PM 11/15/2013 6:52:38 PM

C T20131115-0111CT20131115-0111

LOC : 1737.30LOC: 1737.30

Acq No: 2Acq No: 2

BRAIN WO STBRAIN WO ST

11/15/2013 6:52:40 PM 11/15/2013 6:52:40 PM

CT20131115-0111CT20131115-0111

LOC: 1752.30LOC : 1752.30

159.63mm159.63mm

18.76mm18.76mm

CT20131115-0111CT20131115-0111

LOC: 1777.30LOC: 1777.30

Operating Room

� Preop Diagnosis� Left Subdural Hematoma

� Sagittal suture diastasis

� Procedure� Evacuation of L SDH

� Left craniectomy

� Placement of ICP/PbtO2

� EBL: 1 liter

Jakishev, Amirzhan A

AR01001691AR01001691 MIssion AS64

CT Brain Head wo ContrastCT Brain Head wo Contrast

BRAIN WO ST H45sBRAIN WO ST H45s

11/17/2013 5:00:45 AM 11/17/2013 5:00:45 AM

CT20131117-0001CT20131117-0001

LOC: -783.30LOC: -783.30

A

Page: 20 of 211Page: 20 of 211

Acq No: 3Acq No: 3KVp: 120KVp: 120mA: 257mA: 257Tilt: -14RD: 233RD: 233

11/17/2013 5:00:46 AM 11/17/2013 5:00:46 AM

CT20131117-0001CT20131117-0001

LOC: -768.30LOC: -768.30

IM: 19 SE: 3IM: 19 SE: 3Compressed 11:1Compressed 11:1

PP

C T20131117-0001CT20131117-0001

LOC : -753.30LOC: -753.30

LOC: -738.30LOC: -738.30

Page: 30 of 211 Compressed 11:1

To SICU

� Arrived 2230 Transported on 100% from OR� MAP 93 – ICP 10 = CPP 82

� PbtO2 50 PaCO2 42 PaO2 379

� FIO2 titrated down to 50% within 1 hour

SICU Day 1-2

� ICP 10 to low 20s � MAP 75 ICP 10-22

PbtO2 20-25 mm Hg

� Tx Hypertonic Saline

� Pupillary reaction improving� CS -1.0-0.8 mm/sec

in R

� CS 0.5-0.2 mm /sec in L

MAP

ICP

CPP

PbtO2

R CV

L CV

Improvement if goes in this direction

Day 3: Assessment for MOVEN

� Pt intubated/ventilated

� Sedated RASS -4� Versed & Fentanyl

� ICP requiring drainage

� Assessed for MOVEN� Phase I

� Ready for ergometry evaluation

Safety Screening (Patient must meet all criteria)

MOVEN SCREENRefer to the following criteria in determining mobility level:

M: Myocardial stability50 < HR* < 12090 < SBP* < 20055 < MAP* < 120 *or normal range for ptNo active ischemia x 24 hrsNo new IV antidysrhythmic agents x 24 hrs

O: OxygenationFiO2 ≤ 60%PEEP < 12SPO2 ≥ 92% (88% with activity)10 < RR < 35

V: Vasopressor(s) minimalNo increase in vasopressor infusion in last 2 hrs

E: Engages to voice ----------- ORPt opens eyes to verbal stimulation

N: Neurologic stability ICP <20mmHgAbsence of active seizures x 24hrsCONTRAINDICATIONS:Unstable fxActive bleedingActive fluid resuscitationOpen chest/abdomen

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Focused Mobility with Team Day 4

Before Ergometry

After 20 minutes into Ergometry

ICP

ICP

PbtO2

PbtO2

ICU Course – Days 3-7

ICP controlled with periodic spikes above 20

PbtO2 range 20-35 mm Hg

Day 5 MobilityBefore Ergometry

After 20 minutes into Ergometry

ICP

ICP

PbtO2

PbtO2

Notes PT Day 6

Days 6-8

� Weaning sedation

� ICP controlled / VS stable

� Continues with ergometry

Nurse Note Day 7

Nurse Note Day 8

PT Note Day 10

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Progress from Level I to II

stable intubated patients; may include non-intubated

LEVEL II

RASS -3 AND UP

Goal: Upright sitting;

Increased strength;

Move arms against

gravity

Activity:

• Full chair position

3x/day x 30 min

• Passive ROM

3x/day by RN, PCT

or family

• Turn Q 2hr

• Cycle ergometry (as determined by PT)

Consults:

• PT Consult if not

already following

• OT Consult PRN

(i.e., neuro, splinting

needs)

• SP Consult if pt has

trach

Tolerates Level II

activities, progress

to Level III

PT Note Day 11

Days 10-14� Weaning sedation

� ICP controlled / VS stable� Day 10 ICP & PbtO2

D/C

� Weaned from Vent� 1st extubation Day 8

fail due to secretions

� 2nd extubation Day 13

� Continues with ergometery

Nurse Note Day 10

Nurse Note Day 14

Days 14 Level III

intubated. stable/stabilizing, no contraindications

LEVEL III

RASS -1 AND UP

Goal: Increased trunk

strength; Move legs against

gravity and readiness to

weight bear; Ability to

perform some ADL’s with

assist

Activity:

• Self or assisted turning

Q 2hr

• Sitting EOB with RN, PT,

OT x 15 min

• Full chair position

3x/day x 45-60 min

• Begin transfer to chair

via Sabina lift

• Passive ROM/begin to

encourage AAROM

3x/day by RN, PCT or

family

• Cycle ergometry (as

determined by PT)

Consults:

• OT Consult

• SP Consult if extubated

and not already

following

ARU Consult (if consistently

participating with therapy and

able to follow commands)

10 min for equilibration before determining the patient is intolerant.

Tolerates Level III

activities, progress

to Level IV.

Days 14-25

� Progress with strengthening but has ++ secretions

� GCS improves from 3-5-1T on Day 14 to 4-6-1T by Day 25

� Increasing interaction with family and nurses

� PT/OT/ST working with patient 2x per day each service

PT Note Day 23

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Progressing Level IV-V

stable/stabilizing, no contraindications.

LEVEL IV LEVEL V

RASS 0 AND UP RASS 0 AND UP

Goal: Stand with assist;

March in place and

transfer to chair

Goal: Increase

ambulation distance

Activity:

• Active transfer OOB to

chair with RN, PT, OT

3x/day x 30 min (meal

time)

• Sitting on EOB/stand

at bedside with RN,

PT, OT

• Self or assisted

turning Q 2hr

• Full chair position

3x/day x 60 min

• Encourage

AAROM/AROM

3x/day with RN, PCT,

PT, OT or family

• Cycle ergometry (as

determined by PT)

Consults:

• ARU Consult

Activity:

• OOB to chair

3x/day with RN,

PCT, PT, OT x 60

min

• Ambulate

progressively

longer distances 2-

3x/day with RN,

PCT, PT, OT

• Cycle ergometry

(as determined by

PT)

Tolerates Level IV

activities, progress to Level V.

1 month � Pt has no insurance

� Case Manager working on arrangements for ARU for 4 weeks (Began working on case early in hospital stay)

Nurse Note Day 30

Nurse Note Day 34

Nurse Note Day 40

Outcomes

� Transferred to PCSU on Day 43

� Admitted to ARU on Day 53� By Day 61: independent in bed mobility, improved

transfer, able to walk 150 ft with supervision/contact guard assist; ADLs supervised; cognition overall moderate assist

� Cranioplasty completed on Day 61� Complicated by EDH develop Post op day 1- return

to OR for evacuation

� Transferred to ARU Day 68 to complete ARU

� Discharge home on Day 76� Ambulating 175 feet; ADLs supervised; Cognition – minimal

assist for attention to task; Problem solving min assist level

Conclusion