Bacterial Survey – Gram negatives 2) Aerobic bacilli and cocci Pseudomonas Legionella Neisseria...
-
Upload
gary-obrien -
Category
Documents
-
view
215 -
download
0
Transcript of Bacterial Survey – Gram negatives 2) Aerobic bacilli and cocci Pseudomonas Legionella Neisseria...
Bacterial Survey – Gram negatives2) Aerobic bacilli and cocci
•Pseudomonas
•Legionella
•Neisseria
•Rhizobium
•Agrobacterium
•Methanobacterium
Pseudomonas
• Large taxon; K/K on TSI• “garbage disposals” of the
MO world• Ubiquitous; assoc. with
nosocomial infections• Resistance and virulence
factors/traits• Opportunistic; can affect
compromised hosts– Burn patients– Cancer patients– Transplant patients
Legionella
• Recently discovered (1976) at Legionnaire’s convention
• Found in cool waters• Transported by aerosols• Produces mild-severe
respiratory infections– High fever, cough
• Diagnosis by immunoflourescence
Neisseria I• Diplococci diagnostic• N.gonorrhoeae – produces
urethritis –> cystitis -> pyelonephritis
• 80% males show signs• Female signs inconsistent• Dysuria, polyuria, pyuria• Ascending infections
– Vas deferens blocked– PID
• Systemic infections– Gonorrheal endocarditis– Gonorrheal arthritis– Eyes/pharynx – opthalmia neonate
Co-infections with Chlamydia
Neisseria II
• N. meningitidis – causes ~30% of childhood meningitis
• Initiates as throat infection -> sepsis -> meningitis
• Endotoxin effects to blood-brain barrier
• High mortality
Rhizobium
• symbiotic N2-fixer in the roots of legumes (clover, alfalfa, vetch, peas, beans)
• Expresses nitrogenase at low O2 tension in roots
• Reduces N2 NH2 for incorp into amino acids
• Major route for N into the biosphere
Root nodules on legume species
Agrobacterium
• associative N2-fixer• Plant pathogen – causes
“crown gall”• produced by Ti (tumor-
inducing) plasmid• Ti plasmid is used as a DNA
vector in biotechnology– nitrogenase genes– other genes