Avon Foundation for Women The Avon Foundation for Women, the world’s largest corporate-affiliated philanthropy focused on issues that matter most to women, was founded in 1955 to improve the lives of women. Through 2014, Avon global philanthropy, led by the Avon Foundation, has donated more than $1 billion in more than 50 countries for causes most important to women. Today, Avon philanthropy focuses on funding breast cancer research and access to care through the Avon Breast Cancer Crusade, and efforts to reduce domestic and gender violence through its Speak Out Against Domestic Violence program. Visit www.avonfoundation.org for more information.

Avon Global Breast Cancer Clinical Scholars Program

2016 Request for Applications Release date: July 6, 2015 Application due date: September 9, 2015*

(Early applications are encouraged)

2016 Scholars announced: October 28, 2015 * 11:59 pm EST. Late applications will not be accepted Due to the complexity of the online application, applicants are encouraged to start and submit their application early. Applications may be submitted at any time before the due date.

Avon Foundation for Women New York, NY USA

Programmatic or Technical Support: grantinfo@avonfoundation.org

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Table of Contents Application Instructions I. Funding Objectives 3 II. Guidelines on Use of Award 3 III. Eligibility Criteria 3 IV. Key Dates 4 V. Application Details / Selection Process 4 VI. Scholars Activities 7 VII. Award Notification 7 VIII. Stipend 8 IX. Global Scholar Participation and Reporting Requirements 9

Appendices A. Links to Templates for Required Attachments 9 B. Participating Host Institutions 9 C. Host Institutions and Mentors 10

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Application Instructions I. Funding Objectives To provide clinically-focused scholarship opportunities for breast cancer specialists from outside the United States to receive advanced training at a leading U.S. breast cancer center affiliated with the Avon Foundation for Women. The Avon Global Scholars will take advanced skills back to their home countries to improve treatment and care of women facing breast cancer.

II. Guidelines on Use of Award The program will bring up to 20 outstanding clinician scholars to Avon Foundation-funded breast cancer centers in the U.S. for a 4-week intensive training/preceptorship for them to learn or become expert at new clinical skills. Due to medical malpractice laws in the U.S., these preceptorships will primarily be observational in nature. The exact work plan for the Scholar’s activities and goals will be developed jointly by the Scholar and Mentor during the course of the application process and beyond.

All Scholars will begin April 27, 2016 (tentative) in the U.S. with introductory course work and dialogue with leading breast cancer experts on April 28-29, 2016.

Scholars will travel to the city of their host institution and attend clinical training from May 2 – June 1, 2016.

Scholars will attend the ASCO Annual Meeting, June 3-7, 2016 in Chicago.

Following ASCO, Scholars will return to their home countries.

December 1, 2016: 6-month progress report due to Avon Foundation.

June 1, 2017: Final progress report due to Avon Foundation.

III. Eligibility Criteria Scholars will be physicians (M.D., D.O., F.A.C.P., or equivalent) working in breast cancer clinical care, who are primarily early to mid-career and who will benefit from a short program of advanced, intensive training at a leading U.S. medical center. Eligible applicants are experienced licensed physicians or other health care professionals of any nation who devote a majority of their professional activity to breast cancer patient care. Ideal candidates will have an interest in improving breast cancer screening, treatment and outcomes in their countries. Scholars must have approval from their home institutions and a commitment from their home institution that they have an employment position upon their return home. Scholars must commit to arriving in the U.S. to begin the program on April 27, 2016, attending the entire Avon program, provide progress reports at 6 months and 1 year and agree to share and disseminate their new skills with other experts upon their return home.

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IV. Key Dates July 6, 2015 RFA Release Date September 9, 2015 (11:59pm EST*) Application due (Early applications are encouraged)

October 28, 2015 2016 scholars announced November 16, 2015 Deadline to accept / decline award November 16, 2015 Scholars must apply for Visa, if needed November 16, 2015 Mentors must begin seeking approvals for hosting clinical

scholar April 27, 2016 All Scholars must arrive in the U.S. no later than April 27th April 28-29, 2016 Scholars attend introductory seminar / site visits May 2 – June 1, 2016 Clinical training at host institution June 3-7, 2016 Scholars attend ASCO Annual Meeting June 7-8, 2016 Scholars return home December 1, 2016 6-month progress report due to Avon Foundation June 1, 2017 Final progress report due to Avon Foundation * No late applications will be accepted

V. Application Details / Selection Process All application materials must be in English and must be submitted using the Avon Foundation’s online application program. All application materials and attachments must be submitted electronically. A tutorial on how to use the online system is posted on our website: http://www.avonfoundation.org/assets/2015/global-scholars-tutorial-application-2016.pdf Due to the complexity of the online application, applicants are encouraged to start and submit their application early. Applications may be submitted at any time before the due date. When accessing an application for the first time you will be prompted to create an application account using your email address as the user id and a password of your choosing. It is imperative that you use a functional, monitored email address as your log‐in email, as that is the address that will be recorded in the system to receive email correspondence. To start a new application, go to https://www.grantrequest.com/SID_1102?SA=SNA&FID=35045 To log back into an application that you have previously started and saved, go to https://www.grantrequest.com/SID_1102/Default.asp

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2016 Avon Global Breast Cancer Clinical Scholars Application The application includes the following components:

A. Contact Information B. Program Information C. Choice of Host Institutions D. Preliminary Work Plan (use template) E. Full Resume F. Letter of Support from Home Institution (use template) G. Personal Statement (use template) H. Scientific Publications

A. Contact Information This section requests information about the Applicant including:

First Name (Given Name) and Last Name (Surname or Family Name)

Advanced Degree / Licensure

Date of Birth

Gender

Passport Number

Passport Expiration Date

Country of Citizenship

Field of Clinical Training

Field of Research Training

Applicant’s Home Institution (Primary place of employment)

Applicant’s Title

Mailing Address, including City, State, Postal Code and Country

Phone Number

Email Address

Does Applicant Serve on Government Advisory Boards / Panels? If so, list.

Does Applicant have Relationships with the Avon Company or with Avon Executive Staff? If so, describe.

B. Program Information This section requests information about the Applicant’s home country and program preferences including:

Provide a brief statement of breast cancer demographics and needs in home country

Select three preferred areas of study

Indicate top three choices of host institutions C. Attachments All attachments must be in English. Please upload only one file per attachment category. If you have more than one document in any given category, combine all documents in to one file, then upload that one file. Accepted file formats are doc, docx and pdf. In order for the

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application to be considered complete, the following attachments must be uploaded to the application:

Work Plan (required) Candidates are asked to develop and submit a preliminary work proposal outlining what they wish to learn while in the U.S. If candidate is selected, mentor and scholar will refine and develop the work plan over time. Please use this template: http://www.avonfoundation.org/assets/2015/gs-work-plan-template.docx. Upload work plan to the attachments page of the online application by selecting the work plan upload box, clicking the Browse button and locating the file to be uploaded on your computer, then clicking the Upload button.

Full Resume (Biosketch or CV) (required) Resume must be translated into English. Upload resume on page to the attachments page of the online application by selecting the ‘Biosketch’ upload box, clicking the Browse button and locating the file to be uploaded on your computer, then clicking the Upload button.

Letter of Support from Applicant’s Home Institution (required) The Letter of Support from your home institution must contain specific information as outlined in the template. Please download the template from http://www.avonfoundation.org/assets/2015/gs-institutional-letter-of-support-template.doc. and share it with the appropriate person at your organization to fill out (either the Chair of your Department or the Director of your Institution). Once you receive a fully completed and signed file, upload it to the attachments page of the online application by selecting the ‘Letter of Support from Applicant’s Home Institution’ upload box, clicking the Browse button to locate the file to be uploaded on your computer, then clicking the Upload button.

Personal Statement (required) The Personal Statement must contain specific information as outlined in the template. A template for the personal statement can be found at this URL: http://www.avonfoundation.org/assets/2015/gs-personal-statement-template.doc. Please provide a personal statement discussing your career goals, why you want to participate in the Avon Global Breast Cancer Clinical Scholars Program, your preferred area of focus for advanced training and any additional professional areas of interest you would be working on while at a U.S. breast cancer center. Please download the template and save it to your computer. Once completed, upload the Personal Statement to the attachments page of the online application by selecting the ‘Personal Statement’ upload box, clicking the Browse button to locate the file to be uploaded on your computer, then clicking the Upload button.

Up to two scientific publications may be included (optional) Publications must be in English. Please combine any and all publications into one file, and upload the one file to the attachments page of the online application by selecting the ‘Scientific Publications’ upload box, clicking the Browse button to locate the file to be uploaded on your computer, then clicking the Upload button.

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Additional Letter(s) of Support (optional). Letters of support must be in English. Please combine all letters of support into one file, and upload the one file to the attachments page of the online application by selecting the ‘Additional Letters of Support’ upload box, clicking the Browse button and locating the file to be uploaded on your computer, then clicking the Upload button. Application Selection Process A review panel composed of Avon Foundation Staff, Scientific Advisory Board members and ad-hoc experts as needed will rank applications and select candidates. Attempts will be made to geographically balance scholars. Finalists will be asked to undergo an interview by Avon via phone or skype. Final Selection Process The final selection for Avon Global Scholars awards will be based on a review of the application packages and interviews.

VI. Scholars’ Activities Scholars will be expected to develop a special project or curriculum of activities, in coordination with their assigned host mentor, relating to their interests and desired advanced training. A goal is to have defined skills, defined learning or a defined work-product by the end of the four-week training that can be taken by the scholar back to his/her home institution.

Examples of work products:

Become expert at pathology techniques and quantifying ER/PR or HER2 marker staining

Develop skills in core needle breast biopsy performance, interpretation and patient management

Increase understanding of how to structure and conduct multi-disciplinary review of patient cases and proposed treatment plan

Understand how to develop a system of patient navigation or tracking in areas where barriers exist to delivery of long term follow up clinical care

Increase skills in public health approaches to reducing stigma to breast cancer diagnosis, understanding benefits to cancer screening

VII. Award Notification All applicants will be notified of their selection status in early October 2015 (tentatively October 1, 2015). Applicants selected will have until October 16th to decide whether they will accept or decline the award. In the event a Recipient declines the award, an alternate will be contacted and offered the award. All award decisions are communicated via email and are final.

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VIII. Stipend The Avon Global Scholars stipend is not intended to completely cover all travel or daily expenses during the course of the program. For example, the award does not cover medical care, medical insurance, travel insurance or taxes. All incidentals (room service, telephone, laundry, movies, etc.) will be paid for by the recipient. The recipient is financially responsible for all travel, living and related expenses not covered as part of the Global Scholars program described here.

A weekly stipend of $400.00 USD will be provided to assist with living costs while attending the Avon scholarship. The stipend will be calculated based on the number of weeks the Scholar is studying at the host institution.

In addition to the stipend:

Avon will directly cover the costs of economy class air transportation from Scholar’s home country to New York; from New York to the city of the U.S. host institution; from the city of the U.S. host institution to Chicago; and from Chicago back to Scholar’s home country.

o Scholar must arrange travel through Avon’s travel partner.

Avon will arrange and cover the cost of Scholar’s initial ground transportation upon Scholar’s arrival in New York, to travel from the airport to the host hotel. Scholars will be responsible for arranging and paying for all transportation needs other than when they first arrive in New York from their home country.

Avon will arrange and directly pay the costs of room and tax for housing during scholars’ stay, including a hotel room in New York, housing for the four-week training, and hotel in Chicago. Housing is intended for the Scholar only and is not intended to accommodate any other occupants.

It is expected that most scholars will be on a sabbatical leave from their home institution, and therefore will receive salary support from their home institution and be able to maintain any benefits (health insurance, retirement benefits) at their home institution during the time period that they are Avon Global Scholars.

IX. Global Scholar Participation and Reporting Requirements Avon Global Scholars are required to communicate with their mentors prior to departure for the U.S. Recipients are also encouraged to maintain contact with Mentors and fellow participants following their experience. Scholars are required to arrive in the U.S. no later than April 27, 2016 and attend the entire Global Scholar program. Scholars are required to submit a 6-month progress report due to Avon Foundation on or about December 1, 2016.

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Scholars are required to submit a Final progress report due to Avon Foundation on or about June 1, 2017.

APPENDIX A: Links to Templates for Required Attachments

Work Plan http://www.avonfoundation.org/assets/2015/gs-work-plan-template.docx

Letter of Support from Applicant’s Home Institution http://www.avonfoundation.org/assets/2015/gs-institutional-letter-of-support-

template.doc

Personal Statement http://www.avonfoundation.org/assets/2015/gs-personal-statement-template.doc

APPENDIX B: Participating Host Institutions affiliated with the Avon Foundation for Women. All host sites should provide a multidisciplinary experience.

Institution City State Study Opportunities

Baylor College of Medicine Houston TX Breast imaging

Medical oncology

Pathology

Clinical trials & research

Boston Medical Center

Boston MA Community health & patient navigation

Screening & prevention programs

Cedars Sinai Medical Center Los Angeles

CA Breast imaging

Breast surgery

Community health & patient navigation

Emory University/ Grady Memorial Hospital

Atlanta GA Breast imaging

Breast surgery

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Community health & patient navigation

Houston Methodist Houston TX Breast imaging

Medical Oncology

Screening & prevention programs

Johns Hopkins University-Sidney Kimmel Comprehensive Cancer Center

Baltimore MD Breast imaging

Breast surgery & reconstruction

Medical oncology

Pathology

Massachusetts General Hospital

Boston MA Breast imaging

Breast surgery

Medical oncology

Pathology

Clinical trials & research

New York Presbyterian Hospital-Columbia University Medical Center

New York NY Breast imaging

Breast surgery

Medical oncology

Pathology

Clinical trials & research

Northwestern University Chicago IL Breast imaging

Breast surgery & reconstruction

Pathology

UCSF-San Francisco General Hospital

San Francisco

CA Breast imaging

Community health & patient navigation

Pathology

APPENDIX C: Host Institutions and Mentors Baylor College of Medicine Houston, TX Matthew Ellis, BSc. MB, BChir, PhD, FRCP

Baylor College of Medicine (BCM) was founded in 1900, affiliated with Baylor University in 1903, and became an independent institution in 1969. It was ranked as 1 of the Top 25 medical schools in US News & World Report. Its mission is "To provide state-of-the-art medical care and customer service in an environment dedicated to teaching these principles and discovering new ways to achieve them." BCM is affiliated with 9 hospitals, including Ben Taub General Hospital and its new Smith Clinic of the Harris Health System (HHS). HHS had more than one million outpatient visits in 2011. HHS and BCM have coordinated care for almost 50 years. Dr. Matthew James Ellis is a native of the United Kingdom. He completed his medical degree at Queens’ College & School of Clinical Medicine at the University of Cambridge in England, postgraduate clinical training at the Royal College of Physicians in London and gained a Ph.D. at the Royal Postgraduate Medical School and Imperial Cancer Research Fund at the University of London. After a medical oncology fellowship at the Lombardi Cancer Center, Georgetown University, Washington DC, he was an Assistant Professor there until

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moving to Duke University in 2000 and subsequently to Washington University in St Louis where he served as professor of medicine and section head of breast oncology until 2014. Ellis was recently recruited to Baylor College of Medicine to serve as the Director of the Lester and Sue Smith Breast Center and to hold the C. Kent Osborne Chair of Breast Oncology. Both the McNair Foundation and the Cancer Prevention Research Institute of Texas recently awarded him scholarships. He has been instrumental in developing a Genome Atlas and Therapeutic Road Map for estrogen receptor positive breast cancer by applying genomic techniques to samples accrued through a series of neoadjuvant endocrine therapy trials. Most recently, he has found that metastatic breast tumors harbor mutations and translocations in the estrogen receptor gene that render the tumor resistant to therapies used to block estrogen receptor function. He also pioneered research into the clinical relevance of activating mutations in HER2 and in the deployment of patient-derived xenografts for the pharmacological annotation of breast cancer genomes. He is currently Co-Chair of the translational medicine committee for the NRG cooperative group, co-leader for The Cancer Genome Atlas (TCGA) Breast Project and also serves as a Co-PI for the Clinical Proteomic Tumor Analysis Consortium that endeavors to translate TCGA genomic discoveries into protein-based biomarkers with clinical utility. Dr. Ellis has a successful track record in international clinical and translational research, with recent trainees from Brazil, Chile, Poland and Turkey.

Boston Medical Center Boston, MA Tracy Battaglia, MD, MPH

Boston Medical Center (BMC) is a 496-bed academic medical center located in Boston’s historic South End. BMC provides a full range of pediatric and adult care services, from primary to family medicine to advanced specialty care. Emphasizing community-based care, BMC is committed to providing consistently excellent and accessible health services to all—and is the largest safety-net hospital in New England. BMC’s Breast Health Program incorporates a coordinated multi-specialty approach to care, linking internal medicine, surgical oncology, radiology/mammography, medical oncology, radiation oncology, pathology and other breast health specialists together as one connected team. This patient-centered approach results in rapid access, personalized care and streamlined patient visits. All new patients are given expedited appointments in the Belkin Breast Health Center, where they are seen by either a medical or surgical breast specialist. A cancer care nurse is available to all breast cancer patients as a central contact to offer support and ensure compliance throughout their multispecialty cancer care. They are conveniently located next door to the Belkin Breast Imaging Center if further diagnostic evaluation is needed. An essential part of the program is a weekly multidisciplinary breast cancer conference in which the entire team collaborates on a comprehensive evaluation, and plans the best, most individualized treatment regimen and follow-up care for patients with breast cancer. Dr. Tracy Battaglia is a graduate of Boston University School of Medicine and completed her residency at the Beth Israel Deaconess Medical Center. Additionally, she holds a Masters of Public Health from the Boston University School of Public Health. Dr. Battaglia’s interests include breast and cervical cancer screening in minority and underserved women, reducing errors in follow-up to abnormal mammography, as well as risk perception and screening behaviors in multi-ethnic populations. She is Associate Program Director of the Boston University Preventive Medicine Residency Program and Co-Director of the Avon Breast Health Initiative at Boston Medical Center. Additionally, Dr. Battaglia is a former recipient of Career Development Awards from both NIH and the American Cancer Society and now serves as a Principal Investigator on the Patient Navigation Research Program, a community-based cancer control project supported by the Center to Reduce Cancer Health Disparities at the National Cancer Institute.

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Cedars Sinai Medical Center Los Angeles, CA Armando Giuliano, MD, FACS, FRCSEd

Since its inception in 1902, Cedars-Sinai has evolved to become the largest nonprofit hospital in the western

United States - one that is internationally renowned for the best patient care modern medicine has to offer.

Today, Cedars-Sinai Medical Center is committed to providing superior outpatient, acute and sub-acute

patient care, breakthrough biomedical research, graduate and undergraduate medical education and

community service.

In 2013, for the 18th year in a row, Cedars-Sinai has won the National Research Corporation's Consumer

Choice Award (NRC) for providing the highest quality medical care in the Los Angeles region based on a

survey of area households.

Armando E. Giuliano, MD, is Executive Vice Chair of Surgery for Surgical Oncology, Co-director of the Saul and

Joyce Brandman Breast Center - A Project of Women's Guild and Associate Director for Surgical Oncology at

the Samuel Oschin Comprehensive Cancer Institute. Additionally he is the Linda and Jim Lippman Chair in

Surgical Oncology and serves as Program Director for both the Complex Surgical Oncology Fellowship and

Breast Oncology Fellowship. He is a recognized authority in breast cancer, thyroid cancer, and parathyroid

disease.

After graduating from Fordham University, Dr. Giuliano earned his medical degree from the University of

Chicago. He trained in surgery at the University of California, San Francisco and surgical oncology at the

University of California, Los Angeles.

Dr. Giuliano has served on the editorial boards of prestigious peer-reviewed journals, including the Annals of

Surgical Oncology, Journal of the American College of Surgeons and Breast Cancer Online. A prolific

researcher, he is the author of more than 450 scientific papers and has written book chapters and a textbook.

Dr. Giuliano has earned numerous teaching awards as well as the Hadassah Medical Organization

Outstanding Lifetime Achievement Award in Oncology, the Fellowship of the Royal College of Surgeons in

Edinburgh ad hominem, the National Summit on Breast Cancer Outstanding Medical Advances in Breast

Cancer Award and the Umberto Veronesi Award for international recognition of contributions to the field of

breast cancer and the introduction of sentinel node biopsy for the treatment of breast cancer. In 2011, he

was one of only three physicians to receive the national clinical Excellence Award from Castle Connolly.

Recently he was awarded the Susan G. Komen for the Cure® Brinker Award for Scientific Distinction in Clinical

Research, their highest award for clinical research.

In addition to serving as Chairman of the American College of Surgeons Oncology Group Breast Organ Site

Research Committee, Dr. Giuliano served as Chairman of the Breast Fellowship Program Directors Committee

for the Society of Surgical Oncology. He recently completed his term as President of the International

Sentinel Node Society and currently serves as Secretary for the Society of Surgical Oncology.

Dr. Giuliano's work on nodal metastases has changed the treatment of breast cancer worldwide.

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Emory University/Grady Memorial Hospital Atlanta, GA Sheryl Gabram, MD

One of the largest public hospitals in the Southeast, Grady Memorial Hospital is an internationally recognized teaching hospital with a historic commitment to the health needs of the most vulnerable. Grady Memorial Hospital is a vital part of Emory University School of Medicine's commitment to metro Atlanta and Georgia, and is the location of the Georgia Cancer Center for Excellence. In 2005, Dr. Sheryl Gabram was recruited by Dr. Otis Brawley to lead the AVON Comprehensive Breast Center where she became the principal investigator on the AVON Grant in 2009. In September 2009, Dr. Gabram appointed to Deputy Director of Cancer Center for Excellence at Grady. Then, in October 2011 she was named Surgeon-in-Chief at Grady Memorial Hospital. Dr. Gabram current research focuses on decreasing disparities for breast cancer patients. She serves as the medical liaison for the AVON community outreach and navigation program and is responsible for clinical access to high quality care for patients seen in the AVON Comprehensive Breast Center at Grady. From a predictive health perspective, she collaborates with researchers from Georgia Tech on the examination of breath biomarkers in exhaled specimens as a potential tool for breast cancer disease detection and monitoring. To date Dr. Gabram has authored over 65 peer reviewed journal publications. Dr. Gabram is the recipient of numerous awards and honors. She has been named by the patient resource guide Castle Connolly as one of America’s Top Doctors for seven consecutive years and American’s Top Cancer Doctors for five consecutive years. She has received the Arthur G. Michel, MD Award for Excellence in Breast Care from the Y-ME National Breast Cancer Organization and was selected as one of Atlanta Magazine’s Top Doctors in 2007 and 2009. In the November 2008 Women’s Health magazine she was named one of 5 top oncologists for women in the South. Additionally, she is a member of several prestigious professional societies including a Fellow of the American College of Surgeons, the Society of Surgical Oncology and the American Society of Breast Surgeons. Houston Methodist Houston, TX Jenny C. Chang, MD

Houston Methodist is comprised of a leading academic medical center in the Texas Medical Center® and four community hospitals serving the greater Houston area. Each hospital is staffed with committed personnel who exemplify the core values: integrity, compassion, accountability, respect and excellence. Patient safety, quality and service are the highest priorities. Houston Methodist Hospital, the system's flagship, is consistently listed among U.S. News & World Report's best hospitals and they extend that same level of quality care across the system. Dr. Jenny C. Chang is the Emily Herrmann Chair in Cancer Research and Director of the Cancer Center at Houston Methodist Hospital in Houston, Texas. She obtained her medical degree at Cambridge University in England, and then completed fellowship training in medical oncology at the Royal Marsden Hospital/Institute for Cancer Research in the United Kingdom. She was also awarded a research doctorate from the University of London. There, she developed an interest in breast cancer, particularly in the area of prognostic and predictive markers. She used the clinical situation of locally advanced breast cancer, in which patients are traditionally treated with pre-operative therapy, to assess the use of such markers in predicting treatment response. Her recent work has focused on the intrinsic therapy resistance of cancer stem cells, which has lead to several publications and international presentations. In addition, she has been awarded several federal grants to evaluate novel biologic agents, and holds patents on new technologic advances including high throughput molecular profiling.

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Johns Hopkins University-Sidney Kimmel Comprehensive Cancer Center Baltimore, MD Ben Park, MD, PhD

Since its opening in 1973, the Johns Hopkins University Cancer Center has led the world in deciphering the mechanisms of cancer and new ways to treat it. One of only 40 cancer centers in the country designated by the National Cancer Institute (NCI) as a Comprehensive Cancer Center, the Johns Hopkins Kimmel Cancer Center has active programs in clinical research, laboratory research, education, community outreach, and prevention and control. The Kimmel Cancer Center is the only Comprehensive Cancer Center in the state of Maryland. The Breast Cancer Program at Johns Hopkins includes a diverse group of nationally-recognized specialists in breast cancer research and treatment. The Johns Hopkins Breast Center, is a multidisciplinary breast care program, offering a full spectrum of clinical and support services, from screening and diagnosis to treatment and counseling. The Breast Center provides innovative, integrated, high quality and cost-effective care. It’s state-of-the-art technology and highly-skilled medical professionals are internationally recognized. Patients who visit the Breast Center have access to the most advanced tests and therapies available anywhere. Dr. Ben Park attended The University of Pennsylvania School of Medicine where he received both his MD and PhD degrees in 1995. Dr. Park then trained in Internal Medicine and Hematology/Oncology at The Hospital of The University of Pennsylvania prior to coming to Johns Hopkins where he completed a post-doctoral fellowship in cancer genetics in the laboratory of Drs. Ken Kinzler and Bert Vogelstein. In 2002, Dr. Park joined the faculty at The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in the Breast Cancer Research Program. His lab utilizes sophisticated genetic models to identify, validate and develop targeted therapies for breast cancer. Currently the lab is focused on the PI3 Kinase/AKT signaling pathway, based on the lab's initial finding that the PIK3CA gene is mutated at high frequency in human breast cancers. Dr. Park remains actively involved with all aspects of biomedical research training including teaching of graduate and medical students, post-doctoral fellows, interns, residents and clinical fellows. In addition, Dr. Park continues clinical duties including attending on the inpatient oncology service and seeing breast cancer patients in the outpatient setting. Massachusetts General Hospital Boston, MA Paul Goss, MD, PhD

The third oldest general hospital in the United States and the oldest and largest hospital in New England, Mass General continues its tradition of excellence today. Mass General has consistently placed among the top hospitals on the U.S. News & World Report Best Hospitals Honor Roll since the survey began in 1990. In 2013, Mass General was named No. 2 in the nation and No. 1 in New England based on quality of care, patient safety and reputation in 16 clinical specialties. The Avon Foundation Comprehensive Breast Evaluation Center at Massachusetts General Hospital offers patients the most advanced imaging technologies, such as digital mammography, digital tomosynthesis, and breast MRI as well as Minimally-invasive surgical diagnostics, such as fine needle aspiration which extract the smallest amount of tissue necessary to make an accurate diagnosis. Because of their exclusive focus on breast health, the Comprehensive Breast Evaluation Center offer an expertise available at only a few other centers nationwide. Their entire team, including pathologists, radiologists, surgeons and nurses, specializes exclusively in diagnosing and treating breast disorders, particularly breast cancer, with the latest, most accurate and least invasive techniques available. Dr. Paul Goss is the Chairman of the Avon Foundation Scientific Advisory Board. He also serves as Director of the Avon Foundation Breast Cancer Center of Excellence at Massachusetts General Hospital, Director of

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Breast Cancer Research at MGH and Professor of Medicine at Harvard Medical School. Dr. Goss was educated at the University of Witwatersrand in Johannesburg, South Africa before pursuing postgraduate training in oncology and a doctorate in hormonal mechanisms of breast cancer at the University of London. He subsequently became Professor of Medicine at the University of Toronto and Director of the Breast Cancer Research Program at the Princess Margaret Hospital before joining Massachusetts General Hospital in September 2004. Dr. Goss' principal research interest has been to explore the pivotal role of estrogen in the pathogenesis of breast cancer. He chairs a multitude of international clinical trials. His recently completed MA17 study of letrozole after tamoxifen led to FDA approval and changed the practice of oncology worldwide. His translational laboratory program focuses on tumor signatures and mechanisms of endocrine resistance. Dr. Goss has published over 200 manuscripts, sits on numerous international scientific committees and serves as ad hoc reviewer for many scientific and medical journals.

New York Presbyterian Hospital-Columbia University Medical Center New York, NY Dawn Hershman, MD

New York-Presbyterian Hospital, based in New York City, is the nation's largest not-for-profit, non-sectarian hospital, with 2,409 beds. The Hospital has nearly 2 million inpatient and outpatient visits in a year, including 12,797 deliveries and 195,294 visits to its emergency departments. New York-Presbyterian's 6,144 affiliated physicians and 19,376 staff provide state-of-the-art inpatient, ambulatory and preventive care in all areas of medicine. Patients receiving treatment for breast cancer at New York-Presbyterian are cared for by a multi-disciplinary team of physician-scientists who meet regularly to discuss research, review patients' cases, and plan courses of treatment. These collaborations are important. They allow patients to receive comprehensive care and have access to emerging treatments, typically available in clinical trials. Dr. Dawn Hershman completed her medical degree at The Albert Einstein College of Medicine where she was Alpha Omega Alpha, and completed her internal medicine and oncology fellowship training at Columbia University Medical Center, where she served as Chief Resident. During that time she completed a Masters degree in Biostatistics at the Mailman School of Public Health. She was appointed to a faculty position at Columbia University in 2001 and since that time has developed an expertise in the areas of breast cancer treatment, prevention, survivorship, late-effects of cancer therapy, health outcomes and health disparities research. She has published over 150 scientific articles and has received numerous awards including the Eqig Award for Teaching Excellence, the Avon Foundation Medical Advancement Award and the American Society of Clinical Oncology Advanced Clinical Research Award. Northwestern University Chicago, IL Seema Khan, MD

As one of the country's premier academic medical center hospitals, Northwestern Memorial serves as the primary teaching hospital for Northwestern University Feinberg School of Medicine. They are committed to the advancement of healthcare through clinical innovation, medical education and scientific research. Their medical staff represents virtually every specialty and is comprised of more than 1,600 affiliated physicians who also serve as faculty members of the Feinberg School. Seema A. Khan, MD, professor of surgery in Northwestern University's Feinberg School of Medicine, is the Bluhm Family Professor of Cancer Research. Khan joined the Northwestern faculty in 2000 to develop a program in basic science research for breast cancer. She is co-leader of the Lynn Sage Comprehensive Breast Center and director of the Bluhm Family Program for Breast Cancer Early Detection and Prevention. On the

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cutting-edge of breast cancer research in assessing the association between nipple fluid hormones, gene methylation levels and risk of breast malignancy, Khan also conducts clinical trials of cancer chemoprevention agents. She is Northwestern's principal investigator for the breast cancer trials of the National Surgical Adjuvant Breast and Bowel Project and the American College of Surgeons Oncology Group. She chairs a National Cancer Institute Division of Cancer Prevention protocol investigating the effects of a soy supplement on the breast epithelium of women at high risk of breast cancer. She is co-investigator on a study of the role of alpha-B crystallin expression in breast cancer biology and was principal investigator on a recent study of ductal lavage biomarkers in high-risk women. Khan is an associate member of the Early Detection Research Network and has served on the National Consortium of Breast Centers board of directors and the endocrinology review panel of the Department of Defense. She has also served on peer-review panels of the National Cancer Institute, the Avon Foundation, and the Susan G. Komen Foundation. She is a founding member of the board of directors of the International Society of Cancer Risk Assessment and Management and is a member of the breast cancer screening panel of the National Comprehensive Cancer Center Network. She belongs to many professional societies, including the American College of Surgeons and the Society for the Study of Breast Disease. Khan has published more than 70 peer-reviewed articles as well as six book chapters and 90 abstracts. She is on the program committee of the American Society of Clinical Oncology and will serve as track leader for breast cancer for its 2009 annual meeting. She is a member of the editorial board of the Journal of Clinical Oncology and serves as a reviewer for many professional journals. UCSF-San Francisco General Hospital San Francisco, CA Judith Luce, MD

UCSF is proud of its 140-year long history of providing quality medical care at SFGH, where more than 2,000 UCSF physicians and staff work side-by-side with the dedicated employees of the San Francisco Department of Public Health. Together, the people of SFGH deliver around-the-clock trauma, psychiatric and emergency care, outpatient treatment and a wide range of other important medical services to everyone in San Francisco, regardless of their ability to pay. Since its inception in 2004, the Avon Comprehensive Breast Care Center has provided over 45,000 breast screenings and more than 3,000 breast health procedures. Diagnostic procedures include digital mammography, ultrasound-guided biopsy, stereotactic biopsy, localization procedures, as well as clinical, health education and case coordination services. The Avon Breast Care Center maintains a patient-centered practice that continues to be innovative and responsive to current and anticipated needs. The Avon Comprehensive Breast Care Center, the point of entry for most patients who require breast evaluation, is one of many integral parts of the Avon Comprehensive Breast Health Program at San Francisco General Hospital Medical and Trauma Center (SFGH). Other components of this program include clinical research, behavioral research, patient education, medical oncology and cancer risk evaluation. Judith Luce, MD, Clinical Professor of Medicine at the University of California, San Francisco, is the co-founder and director of the Breast Clinic at San Francisco General Hospital. Dr. Luce received her Bachelor’s degree in biology from the University of California, Santa Cruz and her M.D. from the University of California, San Francisco. Dr. Luce has won many awards, honors, and professional appointments, including recognition for her instruction of medical students and excellence as a scientific investigator. She has been active with the National Cancer Institute and the American Cancer Society. Dr. Luce is also a leader in developing educational and other programs for patients who face obstacles in accessing healthcare.