August 2008 Biotechnology in Livestock Production.

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August 2008 Biotechnology in Livestock Production

Transcript of August 2008 Biotechnology in Livestock Production.

August 2008

Biotechnology in Livestock

Production

August 2008

Definition• the science of altering

genetic and reproductive processes in plants and animals

August 2008

Two areas• genetic engineering

• embryo transfer

August 2008

Genetic Engineering• is based on a technology

involving recombinant DNA

• Deoxyribonucleic acid

August 2008

Genetic Engineering• involves taking a tiny bit of

DNA containing the desired gene from one organism and splicing it into the DNA strand of another organism

August 2008

Genetic Engineering• purpose - to have the

recipient organism take on the characteristic controlled by the transferred gene

August 2008

Examples• disease resistant animals

• growth regulators

• new drugs and vaccines

August 2008

Examples• specify size and sex of

animals

• organism that “eats” oil used in the Persian Gulf

August 2008

BST• Bovine Somatotropin

(Bovine Growth Hormone)

• Somatotropins are proteins that affect the utilization of energy in the body

August 2008

BST• causes energy derived from

feed to be used for milk production rather than weight gain

August 2008

BST• does not reduce energy

available for body maintenance

• increases energy available by improving breakdown of fat and increasing appetite

August 2008

BST• small amounts of BST are

produced naturally in the cow by the pituitary gland

August 2008

BST• previously, the only source

of BST for research has been from pituitary glands of dead cows

August 2008

BST• now, because of genetic

engineering, large quantities of BST can be produced

August 2008

BST• gene that controls BST

production is spliced into the DNA of a bacteria “Agrobacteria”

• is injected into a cow

August 2008

BST• causing increased BST

production in the cow

August 2008

BST• research at the University of

Wisconsin-Madison and Cornell University in New York has showed an average increase of 40% over lactation (305 days)

August 2008

Formula• 20,000# X 40% = 8000# of

extra milk

• 8000# @ $10/cwt =$800

August 2008

Porcine Somatotropin

• is produced naturally by the pituitary gland of the pig

• it acts as a growth regulator

August 2008

PST• production decreases as an

animal matures

August 2008

PST• produced through RDNA

technology

August 2008

PST• how it works

•A. causes an increase in cell division in muscle tissue.

•B. causes decrease in fat storage and increases in accumulation of protein.

August 2008

PST• C. improves feed efficiency

and decrease fat deposition

August 2008

Results• A. increase in feed efficiency

29%• B. increase daily gain 19%• C. increase loin eye area

12%• D. decreases fat 33%

August 2008

Results• must be injected daily

August 2008

Opposition to “Biotech”

• people fear

• production of new uncontrollable disease

• freak animals

August 2008

Opposition to “Biotech”

• long term adverse effects of environment from products

August 2008

Biotech in Crop Production

• lowered costs and increased yields

• improved feeding values

• new corn plant

August 2008

Biotech in Crop Production

• produces higher levels of tryptophan

• amino acid essential for protein formation in an animals body.

August 2008

Biotech in Crop Production

• the first plant patented

August 2008

Other areas researched

• herbicide resistance

• pest resistance

• frost resistance

• salt tolerant

• drought resistance

August 2008

Embryo Transfer• well established in cattle

industry, especially dairy

August 2008

Process• cow is treated with

hormones to cause “superovulation”

• can produce as many as 25 eggs

August 2008

Process• donor cow then artificially

inseminated

August 2008

Process• during this process,

“Recipient” cows or heifers are treated with hormones to synchronize their heat cycle to be the same as the donor cow.

August 2008

Process• after the eggs are fertilized

and before they leave the oviduct, the cow is “flushed” with a saline solution or a solution of egg yolk and D.M.S.O.

August 2008

Process• ovaries and oviducts are

massaged & flushed with fluid-which washes the fertilized eggs out of the body into a cylinder

August 2008

Process• individual embryos are

located under a microscope and put into a straw

August 2008

Process• embryos may be frozen

much the same as cattle semen samples

• first research in the U.S. was done in central WI in 1982

August 2008

Process• freezing protocol now widely

used

• most transfer work is done non-surgically with success rates of approximately 75%

August 2008

Splitting• research has also

successfully split embryos resulting in as many as 5 identical calves

August 2008

Slow Progress• many characteristics are

controlled by multiple genes instead of a single gene

August 2008

Slow Progress• lack of money for research

• government regulations

• environmental groups filing lawsuits to stop research and testing

August 2008

Slow Progress• many farmers don’t support

genetic engineering because they feel we already have surplus production