CURRICULUM VITAE FORM

1. Personal DetailsSurname DOUMBO

Forename(s) Ogobara K.

Title Professor

Position Head of, Department of Epidemiology of Parasitic Diseases and Director MRTC-ICER NIAID-Mali Programmes

Employing organisation Faculty of Medicine, University of Science, Techniques & Technology

Address Box 1805, Bamako, Mali

Telephone +223 20 22 81 09 and 223 66 75 33 96

Email okd@icermali.org

2. Other posts currently heldDate from Position Department Organisation

January, 2014 Chair of the Board University of Ségou Minister of High Education & Research

January, 2008 Director of Malaria Vaccines Programmes at Mali-NIAID ICER

Faculty of Medicine and Dentistry

USTTB, Mali & NIAID/NIH

3. Previous posts heldStart with the most recent

Date from Date to Position Department Organisation

2006- 2012 Mali Programme Director

CVD Maryland -Mali-NIAID ICTDR Programmes

University of Bamako, Mali

2002 2012 Mali Programme DirectorFogarty/ NIH Malaria Training Programme

UoBko & CVD Maryland USTTB, Mali-GIC/NIH

4. Education / TrainingDegrees and/or other professional education (starting with the most recent)

Date Degree (if applicable) Subject Organisation

1992 Agrégation-CAMES Parasitology-Mycology CAMES, Libreville, Gabon

1992 PhD Parasitology Univ of Montpellier

France

5. Scientific contributions and professional recognition (no more than 400 words)Please list:a. Major contributions to health policy or practiceb. Awards and honours received during your career, including major invited talksc. Current memberships of advisory and/or journal editorial boards

Major Contributions to Health Policy or Practices1] Mapping of Malaria epidemiology in Mali fron 1988-1992 : this serve as the backbone of the the NMCP in 1993 and new mapping of Malaria from 1904-2014 for SMC areas identification in Mali (PLoS 2015)

2] Molecular epidemiology of drug resistance (CQ, SP) from 2001-2006 : this collaborative work with our US colleagues led to the discovery of pfcrt and applying and mapping of DHFR & DHPS mutations in Mali. This work led the change drugs policy in Mali (NEJM2001, The Lancet2001, JID 2000.)

3] Clinical trial of SP in ITPp in Mali from 2001-2011. These evidences led to change policy in Mali and Africa (JID 2000, CID 2011, JAMA 2014)

4] SMC trials in Mali and network : from 2006-2012 (MJ, PlosMed..). This work contributed to the WHO SMC Policy recommandation for sahel countries in 2012

5] Development of ICH/GCP clinical trials platform in Mali and critical mass building ; from 2003-2016 (NIAID, CVD-Maryland, GSK, WRAIR, AMANET, IPP, …) and enhanced GCP, GLP in Mali (AJTMH 1998, Science 2005, The Lancet 2008, Science 2011, NEJM 2008, NEJM 2011.).

6] Development of ethics in research in Mali and papers wich has had impact on ethics awarness in Mali and Africa (CID 2005, PLosMed, 2008, MJ 2012…)

Awards and Recognition2015: Portuagal Prestigious national scientific price Awarded by the “Sociedade das Ciencias Medicas de Lisbona (SCML) and the Pfzer Loratories”2013 - Prix International de la Recherche INSERM , France2013 – Chaire d’Ifectiologie des Docteurs Mérieux, Académies, Sciences et Médécine, France2008 – Espagne Prestigious price in collaborative medical research “Prix Prince des Asturies”, Espagne2008- Award of Alpha Omega Alpha US Medical Society , USA2008 – Election à l’Académie Nationale de Médecine, de France2007 - Prix Christophe Mérieux2006 – Prix de Recherche et Sciences en Afrique de la Foundation Path Finder.2009- Officier de la Légion d’Honneur de France2004- International Center of Excellence in Clincal Research –NIAID-NIH2003- Pôle d’Excellence Régioanl de Recherche sur le Paludisme de l’AUF

Editorial Boards and reviewersMali Medical (MM)Bull Soc Path Exo (BSPE)BioMedCentral (BMC)Malaria Journal (MJ)Clinical Infectious Diseases (CID)Journal of Infectious Diseases (JID)The Lancet and The Lancet Infectious DiseasesParasites & vectorsAJTMH

Advisory Boards and International CommitteesIRD/FranceIPP/France and IPD (Dakar)

Malvac (WHO)International Commission of Dracunculosis Eradication Certification (WHO)Malaria Advisor to AFRO DGAdvisor to Islamic Bank Malaria programmes

6. Training record (no more than 300 words): 20 PhDs trained and 30 Masters with carrier path in Mali and 6 are independent t scientist leading their own research groupsPlease name up to five individuals whom you have trained, if any; describe in brief your contribution to their career development; and state both their position at the time you were training them (e.g. postgraduate student, postdoctoral research assistant) and their current position.

1] Pr Amagana Dolo, PharmD & PhD. Mentor of his PharmD and PhD thesisHe is now a full Professor of Parasitology-Mycology CAMES at the Faculty of Pharmacy, USTTB, Mali Senior Scientist and head of ImmunoGenetic (Dogon Fulani) unit at the MRTC, USTTB, Mali and Director of USTTB Doctoral school 2] Pr Mahamadou A. Thera, MD, MS, MPH, PhDI am the Supervisor of his Master and PhD Thesis, He is now a full Professor of Parasitology-Mycology CAMES at the Faculty of Medicine, USTTB, Mali Senior Scientist and head of Mali Malaria Vaccine Developement Unit the MRTC, USTTB, Mali

3] Pr Abdoulaye A. Djimde, PharmD, PhDI am the Mentor of his PhD in Mali and Postdoc supervisorHe is now a full Professor of Parasitology-Mycology CAMES at the Faculty of Pharmacy, USTTB, Mali Senior Scientist and head of Malaria Drug Resistance Unit at the MRTC, USTTB, Mali

4] Pr Alassane A Dicko, MD, PhDI am the Mentor of his MD and PhD ThesisHe is now a full Professor of Epidemiology at the Faculty of Pharmacy, USTTB, Mali Senior Scientist and head of Immuno Epidemiology unit at the MRTC, USTTB, Mali

5] Pr Boureima KouribaI am the Mentor of his PharmD & PhD Thesis He is now a full Professor of Immunology CAMES at the Faculty of Pharmacy, USTTB, Mali Senior Scientist and head of Cell Immunology unit at the MRTC, USTTB, Mali

6] Pr Boubacar Traoré, PharmD, PhDI Chaired f his PhD committee and I am the Mentor of his postdoc .He is now a full Professor of Parasitology-Mycology at the Faculty of Pharmacy, USTTB, Mali Senior Scientist and head of B Cell Immunology and Malaria & Pregnancy unit at the MRTC, USTTB, MaliHe is the Dean of the Faculty of Pharmacy, USTTB, Mali

7] Pr Seydou Doumbia, MD, PhDI am the Mentor of his MD & PhD thesisHe is the Dean of the Faculty of Medicine, USTTB, Mali

8] Pr Abdoulaye Dabo, Msc, ScDI am the Mentor of his Master & ScD thesisSenior scientist and head of the Biological Sciences at the faculty of Pharmacy, USTTB, Mali

9] Pr Samba Diop, MsC PhD (medical anthropology)I am the Mentor of his Master & PhD thesisSenior scientist and lead of social sciences studies at the Mali-NIAID-ICER programme, Member of IRB at USTTB, Mali

10] Pr Ousmane Koita, PharmD, PhDI am the Mentor of his PharmD & PhD ThesisHead of the Apply Molecular Biology LabAt the faculty of Sciences, USTTB, Mali

In collaboration with African (Senegal, Gabon), UE, UK, US, universities; I have also trained & mentored generations of Masters and PhDs (Mali, Guinea, Niger, Tchad, Gabon, France, and UE universities, US universities). We have in Mali 20 others PhDs with a complete career path as full Professors or associate Professor at the University of Mali or working at the MoH and MESRS. Our group are now under training and mentoring 12 PhDs & postdoc. Our Department has 95% of return back in their home country with career path (AJTHM 1998, Science 2011, Warmus H, 2013).

7. Publications

400 listed in Research Gates up to February 2016 and an HFactor of 49.20 and 13000 citationsPlease give citation in full, including title of paper and all authors (unless more than 10, in which case please use ‘et al’, ensuring that your position as author remains clear.)

1- Short Report: Seroreactivity to a Large Panel of Field-Derived Plasmodium falciparum Apical Membrane Antigen 1 and Merozoite Surface Protein 1 Variants Reflects Seasonal and Lifetime Acquired Responses to Malaria. Jason A. Bailey, Jozelyn Pablo, Amadou Niangaly, Mark A. Travassos, Amed Ouattara, Drissa Coulibaly, Matthew B. Laurens, Shannon L. Takala-Harrison, Kirsten E. Lyke, Jeff Skinner, Andrea A. Berry, Algis Jasinskas, Rie Nakajima-Sasaki, Bourema Kouriba, Mahamadou A. Thera, Philip L. Felgner, Ogobara K. Doumbo, and Christopher V. Plowe*. Am. J. Trop. Med. Hyg., 92(1), 2015

02 - a-Thalassaemia trait is associated with antibody prevalence against malaria antigens AMA-1 and MSP-1. Modibo Daou, Elimsaada Kituma, Reginald Kavishe, Jaffu Chilongola, Frank Mosha, Andre´ van der Ven, Bourema Kouriba, Teun Bousema, Robert Sauerwein, and Ogobaro DoumboJournal of Tropical Pediatrics Advance Access published January 20, 2015

03- Urban schistosomiasis and associated determinant factors among school children in Bamako, Mali, West Africa. Abdoulaye Dabo, Adama Z Diarra, Vanessa Machault, Ousmane Touré, Diarra Sira Niambélé, Abdoulaye Kanté, Abdoulaye Ongoiba, Ogobara Doumbo

Infectious Diseases of Poverty 2015

04 - Efficacy of sulphadoxine-pyrimethamine + artesunate, sulphadoxine-pyrimethamine + amodiaquine, and sulphadoxine-pyrimethamine alone in uncomplicated falciparum malaria in MaliHamma Maiga, Abdoulaye A Djimde*, Abdoul H Beavogui, Ousmane Toure, Mamadou Tekete, Cheick Papa O Sangare, Antoine Dara, Zoumana I Traore, Oumar B Traore, Souleymane Dama, Christelle N’Dong, Hamidou Niangaly, Nouhoum Diallo, Demba Dembele, Issaka Sagara and Ogobara K Doumbo, Malaria Journal (2015)

05 - SPODT: An R Package to Perform Spatial PartitioningJean Gaudart, Nathalie Graffeo, Drissa Coulibaly, Guillaume Barbet, Stanilas Rebaudet, Nadine Dessay, Ogobara K. Doumbo, Roch Giorgi; Journal of Statistical Software 2015

06 – A Double-Blind Randomized Placebo-Controlled Clinical Trial of Squanlamine Ointment for tinea capits Treatment. Oumar Coulibaly, Mahamadou A Thera, Abdoulaye K Kone, Goita Siaka, Pierr Traore, Abdoulaye A Djimde, Jean-Michel Brunel, Jean Gaudart, Renaud plarrroux, Ogogara K. Doumbo & Stephane Ranque; Mycopathologia 2015

07 - Ethnic differences in susceptibility to malaria: what have we learned from immuno-epidemiological studies inWest Africa? Arama C, Maiga B, Dolo A, Kouriba B, Traoré B, Crompton PD, Pierce SK, Troye-Blomberg M, Miller LH, Doumbo OK.Acta Trop. 2015 Mar 26.

08 - Access and Use of Interventions to Prevent and Treat Malaria among Pregnant Women in Kenya and Mali: A Qualitative Study’ Jenny Hill1, Kassoum Kayentao, Florence Achieng, Samba Diarra, Stephanie Dellicour, Sory I. Diawara, Mary J. Hamel, Peter Ouma, Meghna Desai, Ogobara K. Doumbo, Feiko O. ter Kuile, Jayne Webster. PLOS ONE | DOI:10.1371/journal.pone.0119848 March 23, 2015

09 - The effect of dosing strategies on the therapeutic efficacy of artesunate amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data. The Worldwide Antimalarial Resistance Network (WWARN) AS-AQ Study GroupBMC Medicine march 2015Sa

10 - Polymorphisms in the K13-Propeller Gene in Artemisinin-Susceptible Plasmodium falciparum Parasites from Bougoula-Hameau and Bandiagara, Mali. Amed Ouattara, Aminatou Kone, Matthew Adams, Bakary Fofana, Amelia Walling Maiga, Shay Hampton, Drissa Coulibaly, Mahamadou A. Thera, Nouhoum Diallo, Antoine Dara, Issaka Sagara, Jose Pedro Gil, Anders Bjorkman, Shannon Takala- Harrison, Ogobara K. Doumbo, Christopher V. Plowe, and Abdoulaye A. Djimde. The American Society of Tropical Medicine and Hygiene April 27, 2015

11 - Genotype combinations of two IL4 polymorphisms influencing IL-4 plasma levels are associated with different risks of severe malaria in the Malian populationSandrine Cabantous. Stéphane Ranque, Belco Poudiougou, Abdoulaye Traore, Sofiane Berbache1, Joana Vitte, Pierre Bongrand, Ogobara Doumbo, Alain. J. Dessein, Laurent Abel, Sandrine Marquet. Immunogenetics, 03 mai 2015

12 - Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function. Silvia Portugal, Christopher M Tipton, Haewon Sohn, Younoussou Kone, Jing Wang, Shanping Li, Jeff Skinner, Kimmo Virtaneva, Daniel E

Sturdevant, Stephen F Porcella, Ogobara K Doumbo, Safiatou Doumbo, Kassoum Kayentao, Aissata Ongoiba, Boubacar Traore, Inaki Sanz, Susan K Pierce, Peter D Crompton Pierce, Peter D CromptonLife 2015;10.7554/eLife.07218

13 - Hemoglobin C trait provides protection from clinical falciparum malaria in Malian children. Travassos MA, Coulibaly D, Laurens MB, Dembélé A, Tolo Y, Koné AK, Traoré K, Niangaly A, Guindo A, Wu Y, Berry AA, Jacob CG, Takala-Harrison S, Adams M, Shrestha B, Mu AZ, Kouriba B, Lyke KE, Diallo DA, Doumbo OK, Plowe CV, Thera MA.J Infect Dis. 2015 May 27.

14 - Understandings of genomic research in developing countries: a qualitative study of the views of MalariaGEN participants in Mali. Karim Traore, Susan Bull, Alassane Niare, Salimata Konate, Mahamadou A. Thera, Dominic Kwiatkowski, Michael Parker and Ogobara K. DoumboBMC Medical Ethics (2015

15 - Safety, reactogenicity and immunogenicity of 2-dose catch-up vaccination with 10-valent pneumococcal non-typeable Haemophilus influenza protein D conjugate vaccine (PHiD-CV) in Malian children in the second year of life: Results from an open studyAlassane Dicko, Yahia Dicko, Amadou Barry, Youssoufa Sidibe, Almahamoudou Mahamar, Gaoussou Santara, Amagana Dolo, Aminata Diallo, Ogobara Doumbo, Fakrudeen Shafi, Nancy François, Juan Pablo Yarzabal, Ana Strezova, Dorota Borys & Lode SchuermanHuman Vaccines & Immunotherapeutics, 21 June 2015

16 - Lice in Mali: frequency of infestation, genotyping, infection rate and case management. Sangaré AK, Doumbo SN, Koné AK, Thera MA, Dabo A, Brouqui P, Raoult D, Doumbo OK.Med Sante Trop. 2015 Jun 12.

17-Preliminary Study of Quinine Pharmacokinetics in Pregnant Women with Malaria-HIV Co-Infection. Kayentao K, Guirou EA, Doumbo OK, Venkatesan M, Plowe CV, Parsons TL, Hendrix CW, Nyunt MM. Am J Trop Med Hyg. 2014 Jan 13.

18-- Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study.Coulibaly SO, Kayentao K, Taylor S, Guirou EA, Khairallah C, Guindo N, Djimde M, Bationo R, Soulama A, Dabira E, Barry B, Niangaly M, Diakite H, Konate S, Keita M, Traore B, Meshnick SR, Magnussen P, Doumbo OK, ter Kuile FO. Malar J. 2014 Jan 31;13:41.

19- Surveillance for antimicrobial drug resistance in under-resourced countries. Vernet G, Mary C, Altmann DM, Doumbo O, Morpeth S, Bhutta ZA, Klugman KP..Emerg.Infect Dis. 2014 Mar;20(3):434-41.

20- PlasmoView: A Web-based Resource to Visualise Global Plasmodium falciparum Genomic Variation. Preston MD, Assefa SA, Ocholla H, Sutherland CJ, Borrmann S, Nzila A, Michon P, Hien TT, Bousema T, Drakeley CJ, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Fairhurst RM, Conway DJ, Roper C, Clark TG. J Infect Dis. 2014 Feb 20.

21- Effectiveness of antenatal clinics to deliver intermittent preventive treatment and insecticide treated nets for the control of malaria in pregnancy in Mali: a household survey. Hill J, Kayentao K, Touré M, Diarwara S, Bruce J, Smedley J, Doumbo OK, Kuile FO, Webster J. PLoS One. 2014 Mar 20;9(3):e92102.

22- Guinea worm (Dracunculiasis) eradication: update on progress and endgame challenges.

Al-Awadi AR, Al-Kuhlani A, Breman JG, Doumbo O, Eberhard ML, Guiguemde RT, Magnussen P, Molyneux DH, Nadim A. Trans R Soc Trop Med Hyg. 2014 Apr 2.

23-- Exposure-dependent control of malaria-induced inflammation in children.Portugal S, Moebius J, Skinner J, Doumbo S, Doumtabe D, Kone Y, Dia S, Kanakabandi K, Sturdevant DE, Virtaneva K, Porcella SF, Li S, Doumbo OK, Kayentao K, Ongoiba A, Traore B, Crompton PD. PLoS Pathog. 2014 Apr 17;10(4):e1004079.

24 - A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. Mark D. Preston, Susana Campino, Samuel A. Assefa, Diego F. Echeverry, Harold Ocholla, Alfred Amambua-Ngwa, Lindsay B. Stewart, David J. Conway, Steffen Borrmann, Pascal Michon, Issaka Zongo, Jean-Bosco Ouedraogo, Abdoulaye A. Djimde, Ogobara K. Doumbo, Francois Nosten, Arnab Pain, Teun Bousema, Chris J. Drakeley, Rick M. Fairhurst, Colin J. Sutherland, Cally Roper & Taane G. Clark NATURE COMMUNICATIONS Received 20 Feb 2014 | Accepted 6 May 2014 | Publis13 Jun 2014

25 - Detection of Bartonella quintana in African Body and Head Lice.Sangaré AK, Boutellis A, Drali R, Socolovschi C, Barker SC, Diatta G, Rogier C, Olive MM, Doumbo OK, Raoult D. Emerg Infect Dis. May 2014; 20(5): 907–908

26 - Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates. Harold Ocholla, Mark D Preston, Mwapatsa Mipando, Anja TR Jensen, Susana Campino, Bronwyn MacInnis, Daniel Alcock6, Anja Terlouw, Issaka Zongo, Jean-Bosco Oudraogo, Abdoulaye A Djimde, Samuel Assefa, Ogobara K Doumbo, Steffen Borrmann, Alexis Nzila, Kevin Marsh, Rick M Fairhurst, Francois Nosten, Tim JC Anderson, Dominic P Kwiatkowski, Alister Craig2, Taane G Clark, Jacqui Montgomery. Journal of Infectious Diseases Advance Access published June 19, 2014

27 - Fréquence du déficit en glucose-6-phosphate déshydrogénase (A-376/202) dans trois groupes ethniques vivant en zone d’endémie palustre au Mali ; Frequency of Glucose-6-phosphate dehydrogenase deficiency (A-376/202) in three Malian ethnic groups. A. Dolo · B. Maiga · A. Guindo · S.A.S. Diakité · M. Diakite · A. Tapily · M. Traoré · B. Sangaré · C. Arama ·M. Daou · O. Doumbo. Reçu le 5 mars 2014 ; accepté le 29 avril 2014. Société de pathologie exotique et Springer-Verlag France 2014

28. Co-infection of Long-Term Carriers of Plasmodium falciparum with Schistosoma haematobium Enhances Protection from Febrile Malaria: A Prospective CohortStudy in Mali. Safiatou Doumbo, Tuan M. Tran2., Jules Sangala1, Shanping Li2, Didier Doumtabe, Younoussou Kone, Abdrahamane Traore, Aboudramane Bathily, Nafomon Sogoba, Michel E. Coulibaly, Chiung-Yu Huang, Aissata Ongoiba, Kassoum Kayentao, Mouctar Diallo, Zongo Dramane, Thomas B. Nutman, Peter D. Crompton, Ogobara Doumbo, Boubacar TraorePLOS Neglected Tropical Diseases | www.plosntds.org 1 September 2014 | Volume 8 | Issue 9 |

29- Delayed anemia assessment in patients treated with oral artemisinin derivatives for uncomplicated malaria: a pooled analysis of clinical trials data from MaliIssaka Sagara, Renaud Piarroux, Abdoulaye Djimde, Roch Giorgi, Kassoum Kayentao, Ogobara K Doumbo and Jean Gaudart, Malaria Journal 2014

30- Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali. Drissa Coulibaly, Mark A Travassos, Abdoulaye K Kone, Youssouf Tolo, Matthew B Laurens, Karim Traore1, Issa Diarra, Amadou Niangaly, Modibo Daou, Ahmadou Dembele, Mody Sissoko, Bouréima Guindo, Raymond Douyon, Aldiouma Guindo, Bourema Kouriba, Mahamadou S Sissoko, Issaka Sagara, Christopher V Plowe, Ogobara K Doumbo, Mahamadou A Thera, Malaria Journal 2014

31: Niangaly H, Djimde AA, Traore B, Sangare CP, Guindo D, Konate D, Diakite M, Diallo N, Maïga-Ascofare O, Sogoba N, Dabo A, Doumbo OK.

Seasonal variability of intestinal helminths and Schistosoma   haematobium in a rural area of the Sahel in Mali. Med Sante Trop. 2013 Jan 30.

32 - Ouattara A, Takala-Harrison S, Thera MA, Coulibaly D, Niangaly A, Saye R, Tolo Y, Dutta S, Heppner DG, Soisson L, Diggs CL, Vekemans J, Cohen J, Blackwelder WC, Dube T, Laurens MB, Doumbo OK, Plowe CV. Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications. J Infect Dis. 2013 Feb 1;207(3):511-9.

33- Kayentao K, Garner P, van Eijk AM, Naidoo I, Roper C, Mulokozi A, MacArthur JR, Luntamo M, Ashorn P, Doumbo OK, ter Kuile FO. Intermittent preventive therapy for malaria during pregnancy using 2 vs 3 or more doses of sulfadoxine-pyrimethamine and risk of low birth weight in Africa: systematic review and meta-analysis. JAMA. 2013 Feb 13;309(6):594-604.

34- S.N. Doumbo, A. Ouattara, M. Diallo, D. Minta, B. Traoré, A. Dolo, I.I. Maiga, M. Maiga, H.A. Traoré, O.K. Doumbo. Evolution des infections opportunistes digestives au cours du VIH SIDA au Mali de 1988 à 2009. Médecine d’Afrique Noir. 2013 ;60(1):31-37.

35- Drissa Coulibaly, Stanislas Rebaudet, Mark Travassos, Youssouf, Matthew Laurens, Abdoulaye K Kone, Karim Traore, Ando Guindo, Issa Diarra, Amadou, Modibo Daou, Ahmadou Dembele, Mody Sissoko, Bourema Kouriba (kouriba@icermali.org),Nadine Dessay, Jean Gaudart, Renaud Piarroux , Mahamadou A Thera, Christopher V Plowe, Ogobara K Doumbo. Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali Malaria Journal 2013, 12:82 doi:10.1186/1475-2875-12-82

36 Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia,Miotto, Olivo1,2,3, Almagro-Garcia, Jacob1,3,4, Manske, Magnus1,3, MacInnis, Bronwyn1,3, Campino, Susana1,3, Rockett, Kirk A.1,3,4, Amaratunga, Chanaki5, Lim, Pharath5,6, Suon, Seila6, Sreng, Sokunthea6, Anderson, Jennifer M.5, Duong, Socheat6, Nguon, Chea6, Chuor, Char Meng6, Saunders, David7, Se, Youry8, Lon, Chantap8, Fukuda, Mark M9,7, Amenga-Etego, Lucas10, Hodgson, Abraham V. O.10, Asoala, Victor10, Imwong, Mallika11,2, Takala-Harrison, Shannon12, Nosten, Francois13,14,2, Su, Xin-Zhuan5, Ringwald, Pascal15, Ariey, Frédéric16, Dolecek, Christiane17,14, Hien, Tran Tinh17,14, Boni, Maciej F.17,14, Thai, Cao Quang17, Amambua-Ngwa, Alfred18, Conway, David J.19,18, Djimdé, Abdoulaye A.20, Doumbo, Ogobara K.20, Zongo, Issaka21, Ouedraogo, Jean-Bosco21, Alcock, Daniel3, Drury, Eleanor3, Auburn, Sarah22, Koch, Oliver1, Sanders, Mandy3, Hubbart, Christina4, Maslen, Gareth1,3, Ruano-Rubio, Valentin1,3,4, Jyothi, Dushyanth1,3, Miles, Alistair1,4, O’Brien, John1,4, Gamble, Chris23, Oyola, Samuel O.3, Rayner, Julian C.3, Newbold, Chris I.1,3,24, Berriman, Matthew3, Spencer, Chris C. A.4, McVean, Gilean4, Day, Nicholas P.2,14, White, Nicholas J.2,14, Bethell, Delia7, Dondorp, Arjen M.2,14, Plowe, Christopher V.12, Fairhurst, Rick M.5, Kwiatkowski, Dominic. Nat Genet. 2013 Apr 28. doit: 10.1038/ng.2624.

37 Factors associated with coverage of praziquantel for schistosomiasis control in the community-direct intervention (CDI) approach in Mali (West Africa). Dabo A, Bary B, Kouriba B, Sankaré O, Doumbo O. Infect Dis Poverty. 2013 Jun 10;2(1):11.

38- [Prevalence of Plasmodium falciparum, anemia and molecular markers of chloroquine and sulfadoxine-pyriméthamine resistance in delivered women in Fana, Mali]. Doumbo S, Ongoiba OA, Doumtabé D, Dara A, Ouologuem TD, Kayentao K, Djimdé A, Traoré B, Doumbo OK. Bull Soc Pathol Exot. 2013 Aug;106(3):188-92.

39- Inter-observer agreement according to malaria parasite density.Billo MA, Diakité M, Dolo A, Diallo M, Poudiougou B, Diawara SI, Johnson ES, Rice JC, Krogstad DJ, Doumbo OK. Malar J. 2013 Sep 22;12(1):335.

40- Human candidate polymorphisms in sympatric ethnic groups differing in malaria susceptibility in Mali. Maiga B, Dolo A, Touré O, Dara V, Tapily A, Campino S, Sepulveda N, Risley P, Silva N, Corran P, Rockett KA, Kwiatkowski D; MalariaGEN Consortium, Clark TG, Troye-Blomberg M, Doumbo OK. PLoS One. 2013 Oct 2;8(10):e75675.

41 - Fcgamma Receptor IIa- H131R polymorphism and malaria susceptibility in sympatric ethnic groups, Fulani and Dogon of Mali.Maiga B, Dolo A, Touré O, Dara V, Tapily A, Campino S, Sepulveda N, Corran P, Rockett K, Clark T, Blomberg MT, Doumbo O. Scand J Immunol. 2013 Oct 5.

42 - Extended Safety, Immunogenicity and Efficacy of a Blood-Stage Malaria Vaccine in Malian Children: 24-Month Follow-Up of a Randomized, Double-Blinded Phase 2 Trial. Laurens MB, Thera MA, Coulibaly D, Ouattara A, Kone AK, Guindo AB, Traore K, Traore I, Kouriba B, Diallo DA, Diarra I, Daou M, Dolo A, Tolo Y, Sissoko MS, Niangaly A, Sissoko M, Takala-Harrison S, Lyke KE, Wu Y, Blackwelder WC, Godeaux O, Vekemans J, Dubois MC, Ballou WR, Cohen J, Dube T, Soisson L, Diggs CL, House B, Bennett JW, Lanar DE, Dutta S, Heppner DG, Plowe CV, Doumbo OK. PLoS One. 2013 Nov 18;8(11):e79323.

43 Merepen A. Guindo, Joseph P. Shott, RenionSaye, Moussa L. Diakite, SintrySanogo, Moussa B. Dembele, Sekouba Keita, Marie C. Nagel, Ruth D. Ellis, Joan A. Aebig, Dapa A. Diallo and Ogobara K. Doumbo. Promoting Good Clinical Laboratory Pratices and laboratory Accreditation to support clinical trials in Sub-Saharan Africa. Am. J. Trop. Med. Hyg., 86(4), 2012, pp. 573-579 :

44: Dicko A, Diallo AI, Tembine I, Dicko Y, Dara N, Sidibe Y, Santara G, Diawara H, Conaré T, Djimde

A, Chandramohan D, Cousens S, Milligan PJ, Diallo DA, Doumbo OK, Greenwood B. Intermittent

Preventive Treatment of Malaria Provides Substantial Protection against Malaria in Children Already

Protected by an Insecticide-Treated Bednet in Mali: A Randomised, Double-Blind, Placebo-Controlled

Trial.

PLoS Med. 2011 Feb 1;8(2):e1000407.

45 Beavogui AH, Djimde AA, Gregson A, Toure AM, Dao A, Coulibaly B, Ouologuem D, Fofana B, Sacko A, Tekete M, Kone A, Niare O, Wele M, Plowe CV, Picot S, DoumboOK. Low infectivity of Plasmodium falciparum gametocytes to Anopheles gambiaefollowing treatment with sulfadoxine-pyrimethamine in Mali. Int J Parasitol. 2010 Aug 15;40(10):1213-20.

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120: Plowe CV, Cortese JF, Djimde A, Nwanyanwu OC, Watkins WM, Winstanley PA,Estrada-Franco JG, Mollinedo RE, Avila JC, Cespedes JL, Carter D, Doumbo OK.Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroatesynthase and epidemiologic patterns of pyrimethamine-sulfadoxine use andresistance. J Infect Dis. 1997 Dec;176(6):1590-6.

121: Doumbo O, Rossignol JF, Pichard E, Traore HA, Dembele TM, Diakite M, Traore F, Diallo DA. Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiencysyndrome in tropical Africa. Am J Trop Med Hyg. 1997 Jun;56(6):637-9.

122: Bouvier P, Rougemont A, Breslow N, Doumbo O, Delley V, Dicko A, Diakite M,Mauris A, Robert CF. Seasonality and malaria in a west African village: does high parasite density predict fever incidence? Am J Epidemiol. 1997 May1;145(9):850-7.

123: Bruno JM, Feachem R, Godal T, Nchinda T, Ogilvie B, Mons B, Mshana R, Radda G, Samba E, Schwartz M, Varmus H, Diallo S, Doumbo O, Greenwood B, Kilama W,Miller LH, da Silva LP. The spirit of Dakar: a call for action on malaria.Nature. 1997 Apr 10;386(6625):541.

124: Bouvier P, Doumbo O, Breslow N, Robert CF, Mauris A, Picquet M, Kouriba B,Dembele HK, Delley V, Rougemont A. Seasonality, malaria, and impact ofprophylaxis in a West African village I. Effect of anemia in pregnancy. Am J Trop Med Hyg. 1997 Apr;56(4):378-83.

125: Plowe CV, Djimde A, Wellems TE, Diop S, Kouriba B, Doumbo OK. Communitypyrimethamine-sulfadoxine use and prevalence of resistant Plasmodium falciparumgenotypes in Mali: a model for deterring resistance. Am J Trop Med Hyg. 1996, Nov;55(5):467-71.

126: Traore HA, Maiga MY, Sogodogo S, Dembele M, Sidibe TA, Diallo D, Diallo AN, Guindo A, Pichard E, Doumbo O. [Importance of hepatic bilharziasis in liverpathologies in the internal medicine department of the National Hospital

of Point "G", Bamako-Mali]. Dakar Med. 1996;Spec No:26-8.

127: Dabo A, Traoré HA, Diakité M, Kouriba B, Camara F, Coulibaly CO, Sacko M,Doumbo O. [Echographic morbidity due to Schistosoma haematobium in a peripheraldistrict of Bamako in Mali, Missabougou]. Bull Soc Pathol Exot. 1995;88(1):11-4.

128: Tolle R, Früh K, Doumbo O, Koita O, N'Diaye M, Fischer A, Dietz K, Bujard H. A prospective study of the association between the human humoral immune response to Plasmodium falciparum blood stage antigen gp190 and control of malarial infections. Infect Immun. 1993 Jan;61(1):40-7.

129: Doumbo O, Dabo A, Diallo M, Doucoure B, Akory AI, Balique H, Quilici M.[Epidemiology of human urban schistosomiasis in Bamako in Mali (the case of the"populous" quarter of Bankoni)]. Med Trop (Mars). 1992 Oct-Dec;52(4):427-34.

130: Doumbo O, Toure A, Coulibaly B, Koita O, Traore B, Dolo A, Diallo M, Diallo AN, Quilici M. [Incidence of malaria and S hemoglobinopathy in the pediatrichospital milieu in Bamako, Mali]. Med Trop (Mars). 1992 Apr-Jun;52(2):169-74.

131: Doumbo O, Soula G, Kodio B, Perrenoud M. [Ivermectin and pregnancy in masstreatment in Mali]. Bull Soc Pathol Exot. 1992;85(3):247-51.

132: Früh K, Doumbo O, Müller HM, Koita O, McBride J, Crisanti A, Touré Y, Bujard H. Human antibody response to the major merozoite surface antigen of Plasmodium falciparum is strain specific and short-lived. Infect Immun. 1991, Apr;59(4):1319-24.

133: Duke BO, Soula G, Zea-Flores G, Bratthauer GL, Doumbo O. Migration and death of skin-dwelling Onchocerca volvulus microfilariae after treatment withivermectin. Trop Med Parasitol. 1991 Mar;42(1):25-30.

134: Doumbo O, Traore SF, Sow Y, Dembele M, Soula G, Coulibaly A, Dolo A, Sangare O, Koita O, Pichard E, et al. [Impact of curtains and blankets impregnated with permethrin on the malarial indicators and the number of malarial attacks per child in a village in an area hyperendemic for malaria on the Malian savannahBull Soc Pathol Exot. 1991;84(5 Pt 5):761-74.

135:Rougemont A, Doumbo O, Bouvier M, Soula G, Perrin L, Tamoura B, Yerly S, Dolo A, Brenner E, Kodio B, et al. Hypohaptoglobinaemia as an epidemiological and clinical indicator for malaria. Results of two studies in a hyperendemic region in West Africa. The Lancet. 1988 Sep 24;2(8613):709-12.

8. Total number of peer reviewed publications which you have authored/co-authored. Please exclude abstracts and reviews.

400 in pubmed & Research gate with an H factor of 49, 20

1. Research funding List all research funding held in the last five years (most recent first). For current grants, please indicate the number of hours per week spent on activities related to that grant

Project Title Names of grant holders (include your role)

Awarding Body Amount Grant period

Capacity Strengthening in Malaria drugs and vaccines Trials in Mali

Univ of Bamako – Doumbo = Program Director,

AFD/MAE, France 2,000,000€ 2014-2018

Chair Drs MERIEUX & GIRAFE project

USTTB, Doumbo, PIUniv. Of Marseille, Bamako, Dakar, Conakry, Niamey

Académies, Sciences, Médecine et FMérieux

500 000€ 2004-2015

WANETAM network Univ of Dakar & UoBko IPD, Ghana, Gambia, Nigeria, Burkina FasoPD = Pr MBOUPMalaria Coor= Doumbo

EDTCP 1 3,500,000€ 2009-2015

Malaria vaccines Trials in Mali, ICER NIAID-Mali

USTTB, LMIV-NIAID & MRTCPI = P. DuffyMali PD = Doumbo

NIAID-NIH Intramural 1000 000 $ Per year

PARAAF/RELACS NetworkFor TND control in Africa

USTTB, MaliPD=DoumboPartners: Bénin, Ghana, Gabon, IRD, Mauritania

IRD/MAE, France 190,000 € 2003-2015

Deltas/WT UCAD, USTTB Welcome Trust 5000 000$ 2016-2021PI=Pr Oumar GayeDoumbo =Mali program Director

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