ars.els-cdn.com · Web view(67) Lucenteforte E, La VC, Silverman D, Petersen GM, Bracci PM, Ji BT,...

Webappendix for Aune D, Mahamat-Saleh Y, Norat T, Riboli E. Tobacco smoking and the

risk of pancreatitis: a systematic review and meta-analysis of prospective studies.

Pancreatology

Supplementary text

PubMed search terms:

1) “body mass index” OR body mass index[MeSH] OR BMI OR overweight OR overweight[MeSH] OR obesity OR obesity[MeSH] OR anthropometry OR anthropometry[MeSH] OR fatness OR “body fatness” OR “abdominal fatness” OR “abdominal obesity” OR abdominal obesity[MeSH] OR “waist circumference” OR "hip circumference" OR “waist-to-hip ratio” OR waist-to-hip ratio[MeSH] OR adiposity OR adiposity[MeSH] OR "weight gain" OR weight gain[MeSH] OR "weight change" OR weight change[MeSH] OR “weight loss” OR weight loss[MeSH]

2) diabetes OR diabetes[MeSH] OR glucose OR glucose[MeSH] OR "medical history" OR medical history[MeSH]

3) "physical activity" OR physical activity[MeSH] OR exercise OR exercise[MeSH] OR sports OR sports[MeSH] OR walking OR walking[MeSH] OR biking OR bicycling OR bicycling[MeSH] OR running OR running[MeSH] OR fitness OR "exercise test" OR exercise test[MeSH] OR inactivity OR sedentary

4) smoking OR smoking[MeSH] OR cigarette OR cigarette[MeSH] OR cigarettes OR cigarettes[MeSH] smoke OR smoke[MeSH] OR tobacco OR tobacco[MeSH] OR snus OR snuff OR snuff[MeSH] OR "environmental tobacco smoke” OR environmental tobacco smoke[MeSH] OR “passive smoking” OR passive smoking[MeSH] OR “smoking cessation" OR smoking cessation[MeSH]

5) pancreatitis OR pancreatitis[MeSH]

6) "case-control" OR cohort OR prospective OR longitudinal OR retrospective OR "follow-up" OR "cross-sectional" OR "hazard ratio" OR "hazard ratios" OR "relative risk" OR "relative risks" OR "incidence rate ratio" OR "incidence rate ratios" OR "odds ratio" OR odds ratios OR incidence

7) 1 OR 2 OR 3 OR 4

8) 7 AND 5 AND 6

Embase search terms

1) body mass index OR BMI OR overweight OR obesity OR anthropometry OR fatness OR body fatness OR abdominal fatness OR abdominal obesity OR waist circumference OR hip circumference OR waist-to-hip ratio OR adiposity OR weight gain OR weight change OR weight loss

2) body mass index/ OR BMI/ OR overweight/ OR obesity/ OR anthropometry/ OR fatness/ OR body fatness/ OR abdominal fatness/ OR abdominal obesity/ OR waist circumference/ OR hip circumference/ OR waist-to-hip ratio/ OR adiposity/ OR weight gain/ OR weight change/ OR weight loss/

3) diabetes OR glucose OR medical history

4) diabetes/ OR glucose/ OR medical history/

5) physical activity/ OR exercise/ OR sports/ OR walking/ OR biking/ OR bicycling/ OR running/ OR fitness/ OR exercise test/ OR inactivity/ OR sedentary/

6) physical activity OR exercise OR sports OR walking OR biking OR bicycling OR running OR fitness OR exercise test OR inactivity OR sedentary

7) smoking OR smoke OR tobacco OR snus OR snuff OR environmental tobacco smoke OR passive smoking OR smoking cessation

8) smoking/ OR smoke/ OR tobacco/ OR snus/ OR snuff/ OR environmental tobacco smoke/ OR passive smoking/ OR smoking cessation/

9) pancreatitis

10) pancreatitis/

11) case-control OR cohort OR prospective OR longitudinal OR retrospective OR follow-up OR cross-sectional OR hazard ratio OR hazard ratios OR relative risk OR relative risks OR incidence rate ratio OR incidence rate ratios OR odds ratio OR odds ratios OR incidence

12) 1 OR 2 OR 3 OR 4 OR 5 OR 6 OR 7 OR 8

13) 9 OR 10

14) 12 AND 13 AND 11

Supplementary Table 1. List of excluded studies and exclusion reasons

Exclusion reason Reference number

Abstract (1-10)

Case-control study (11-35)

Case only study (36-39)

Cross-sectional study (40-45)

Crude assessment of smoking (46;47)

Duplicate (48-50)

Meta-analysis (51-54)

No risk estimates (55;56)

Not relevant data (57;58)

Not relevant outcome (59-78)

Patient populations (79-85)

Review (86-94)

Reference List

(1) Bitton A. Smoking linked to increased risk of pancreatitis. Journal of Clinical Outcomes Management 2009;16(8):351-2.

(2) Anderson KE, Prizment AE, Jensen EH, Virnig BA, Folsom AR. Risk factors for pancreatitis in older women: The iowa women's health study (IWHS). American Journal of Epidemiology Conference: 43rd Annual Meeting of the Society for Epidemiologic Research, SER 2010;171.

(3) Liao W-C, Lin H-H, Chang H-Y. Cigarette smoking, alcohol consumption, and the risk of pancreatitis: A population-based cohort study in Taiwan. Gastroenterology Conference: Digestive Diease Week 2012;142(5):S54-S55.

(4) Munigala S, Gelrud A, Agarwal B, Conwell D, Scherrer J. Smoking may represent an independent risk factor for the development of acute pancreatitis. Gastroenterology Conference: Digestive Disease Week 2013;May.

(5) Bertilsson S, Kalaitzakis E. Natural history of acute pancreatitis: Results of a population-based cohort study. Gastroenterology Conference: Digestive Disease Week 2014;146(5):S137.

(6) Su Y-C. Bidirectional relationship between diabetes and acute pancreatitis: A population-based cohort study in Taiwan. Annals of Emergency Medicine Conference: American College of Emergency Physicians, ACEP 2015;66(4):S119-S120.

(7) Gonzalez-Perez A, Schlienger RG, Rodriguez LAG. Risk of acute pancreatitis in association with type 2 diabetes mellitus. Pharmacoepidemiology and Drug Safety Conference: 26th International Conference on Pharmacoepidemiology and Therapeutic Risk Management Brighton United Kingdom Conference Publication: 1919;19(S1):-S2.

(8) Majumder S, Bastian L, Gierisch J. The role of smoking and the development of acute pancreatitis: A systematic review. American Journal of Gastroenterology Conference: 78th Annual Scientific Meeting of the American College of Gastroenterology San Diego, CA United States Conference Publication 2013;108:S84.

(9) Andriulli A, Botteri E, Almasio P, Uomo G, Vantini I, Maisonneuve P. Smoking as a co-factor for causation of chronic pancreatitis: A meta-analysis. Gastroenterology Conference: Digestive Disease Week, DDW 2009;136(5 (S1)):A388.

(10) Janarthanan S, Adler DG. Smoking and its association to acute and chronic pancreatitis; a meta-analysis to establish overall risk. Gastroenterology Conference: Digestive Diease Week 2012;142(5 (S1)):S850.

(11) Bourliere M, Barthet M, Berthezene P, Durbec JP, Sarles H. Is tobacco a risk factor for chronic pancreatitis and alcoholic cirrhosis? Gut 1991 Nov;32(11):1392-5.

(12) Levy P, Mathurin P, Roqueplo A, Rueff B, Bernades P. A multidimensional case-control study of dietary, alcohol, and tobacco habits in alcoholic men with chronic pancreatitis. Pancreas 1995 Apr;10(3):231-8.

(13) Talamini G, Bassi C, Falconi M, Frulloni L, Di F, V, Vaona B, Bovo P, Rigo L, Castagnini A, Angelini G, Vantini I, Pederzoli P, et al. Cigarette smoking: an independent risk factor in alcoholic pancreatitis. Pancreas 1996 Mar;12(2):131-7.

(14) Talamini G, Vaona B, Bassi C, Bovo P, Damoc T, Mastromauro M, Falconi M, Vantini I, Cavallini G, Pederzoli P. Alcohol intake, cigarette smoking, and body mass index in patients with alcohol-associated pancreatitis. J Clin Gastroenterol 2000 Dec;31(4):314-7.

(15) Lin Y, Tamakoshi A, Hayakawa T, Ogawa M, Ohno Y. Cigarette smoking as a risk factor for chronic pancreatitis: a case-control study in Japan. Research Committee on Intractable Pancreatic Diseases. Pancreas 2000 Aug;21(2):109-14.

(16) Yadav D, Hawes RH, Brand RE, Anderson MA, Money ME, Banks PA, Bishop MD, Baillie J, Sherman S, DiSario J, Burton FR, Gardner TB, et al. Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis. Arch Intern Med 2009 Jun 8;169(11):1035-45.

(17) Canha MI, Oliveiros B, Franco C, Figueiredo P. The lifestyle influence on alcoholic pancreatitis versus alcoholic liver disease: a case-control study. Scand J Gastroenterol 2017 Nov;52(11):1278-85.

(18) Diehl AK, Holleman DR, Jr., Chapman JB, Schwesinger WH, Kurtin WE. Gallstone size and risk of pancreatitis. Arch Intern Med 1997 Aug 11;157(15):1674-8.

(19) Cavallini G, Talamini G, Vaona B, Bovo P, Filippini M, Rigo L, Angelini G, Vantini I, Riela A, Frulloni L, Di F, V, Brunori MP, et al. Effect of alcohol and smoking on pancreatic lithogenesis in the course of chronic pancreatitis. Pancreas 1994;9(1):42-6.

(20) Jarosz M, Sekula W, Figurska K, Rychlik E. Pancreatic cancer and tobacco smoking, diet, and chronic pancreatitis in Poland, in 1960-2004. Gastroenterologia Polska 2007;14(5):339-45.

(21) DeBenedet A, Raghunathan T, Wing J, Wamsteker E, DiMagno M. Current alcohol use and former cigarette smoking are new risk factors for post-ercp pancreatitis. A case-control study. Pancreas Conference: 39th Annual Meeting of the American Pancreatic Association Chicago, IL United States Conference Publication 2008;37(4):467.

(22) DeBenedet AT, Raghunathan TE, Wing JJ, Wamsteker E, DiMagno MJ. Alcohol Use and Cigarette Smoking as Risk Factors for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis. Clinical Gastroenterology and Hepatology 2009;7(3):353-8.

(23) Mori M, Hariharan M, Anandakumar M, Tsutsumi M, Ishikawa O, Konishi Y, Chellam VG, John M, Praseeda I, Priya R, Narendranathan M. A case-control study on risk factors for pancreatic diseases in Kerala, India. Hepato-Gastroenterology 1999;46(25):25-30.

(24) Talamini G, Bassi C, Falconi M, Sartori N, Salvia R, Rigo L, Castagnini A, Di F, V, Frulloni L, Bovo P, Vaona B, Angelini G, et al. Alcohol and smoking as risk factors in chronic pancreatitis and pancreatic cancer. Digestive Diseases and Sciences 1999;44(7):1303-11.

(25) Blomgren KB, Sundstrom A, Steineck G, Wiholm BE. Obesity and treatment of diabetes with glyburide may both be risk factors for acute pancreatitis. Diabetes Care 2002;25(2):298-302.

(26) Blomgren KB, Sundstrom A, Steineck G, Genell S, Sjostedt S, Wiholm B-E. A Swedish case-control network for studies of drug-induced morbidity - Acute pancreatitis. European Journal of Clinical Pharmacology 2002;58(4):275-83.

(27) Ockenga J, Vogel A, Teich N, Keim V, Manns MP, Strassburg CP. UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer. Gastroenterology 2003;124(7):1802-8.

(28) Brand H, Diergaarde B, O'connell MR, Whitcomb DC, Brand RE. Variation in the F-glutamyltransferase 1 gene and risk of chronic pancreatitis. Pancreas 2013;42(5):836-40.

(29) Singh S, Chang H-Y, Richards TM, Weiner JP, Clark JM, Segal JB. Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: A population-based matched case-control study. JAMA Internal Medicine 2013;173(7):534-9.

(30) Han S, Kheder J, Bocelli L, Wassef W. Smoking cessation comparison in chronic pancreatitis patients. American Journal of Gastroenterology Conference: 79th Annual Scientific Meeting of the American College of Gastroenterology Philadelphia, PA United States Conference Publication 2014;109:S71.

(31) Kume K, Masamune A, Ariga H, Shimosegawa T. Alcohol consumption and the risk for developing pancreatitis a case-control study in Japan. Pancreas 2015;44(1):53-8.

(32) Di Leo M, Zuppardo RA, Mariani A, Bianco M, Rogger T, Leandr G, Testoni PA, Cavestro GM. Chronic pancreatitis and associated factors: A single center case control study.

Pancreatology Conference: 47th Annual Meeting of the European Pancreatic Club, EPC 2015;(var.pagings):June.

(33) Polonikov AV, Samgina TA, Nazarenko PM, Bushueva OY, Ivanov VP. Alcohol consumption and cigarette smoking are important modifiers of the association between acute pancreatitis and the PRSS1-PRSS2 locus in men. Pancreas 2017;46(2):230-6.

(34) Di LM, Leandro G, Singh SK, Mariani A, Bianco M, Zuppardo RA, Goni E, Rogger TM, Di MF, Guslandi M, De CF, Del MA, et al. Low alcohol and cigarette use is associated to the risk of developing chronic pancreatitis. Pancreas 2017;46(2):225-9.

(35) Aghdassi AA, Schneider A, Kahl M, Schutte K, Kuliaviene I, Salacone P, Lutz J, Tukiainen E, Simon P, Schauer B, Uomo G, Hauge T, et al. Analysis of lifestyle factors in patients with concomitant chronic pancreatitis and liver cirrhosis. Pancreatology 2017;17(5):698-705.

(36) Voirol M, Infante F, Brahime-Reteno O, Raymond L, Hollenweger V, Loizeau E. [Alcohol, tobacco and food consumption in pancreatic diseases. Preliminary results of a study of 1000 cases]. Schweiz Med Wochenschr 1980 May 31;110(22):854-5.

(37) Imoto M, DiMagno EP. Cigarette smoking increases the risk of pancreatic calcification in late-onset but not early-onset idiopathic chronic pancreatitis. Pancreas 2000 Aug;21(2):115-9.

(38) Diaconu B, Mocan T, Ciobanu L. Risk factors in patients with chronic pancreatitis in Romania. Rom J Intern Med 2008;46(4):331-6.

(39) Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, et al. Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis. Am J Gastroenterol 2016 Oct;111(10):1488-96.

(40) Law R, Parsi M, Lopez R, Zuccaro G, Stevens T. Cigarette smoking is independently associated with chronic pancreatitis. Pancreatology 2010;10(1):54-9.

(41) Kadiyala V, Lee LC, Rosenblum J, Paulo JA, Sainani NI, Mortele K, Banks PA, Conwell DL. Cigarette smoking impacts chronic pancreatitis clinical feature score, severity index and pancreas imaging severity. Pancreas Conference: 42nd Annual Meeting of the American Pancreatic Association Chicago, IL United States Conference Publication 2011;40(8):1330.

(42) Castineira-Alvarino M, Lindkvist B, Luaces-Regueira M, Iglesias-Garcia J, Larino-Noia J, Nieto-Garcia L, Dominguez-Munoz JE. The role of high fat diet in the development of complications of chronic pancreatitis. Clinical Nutrition 2013;32(5):830-6.

(43) Yang H, Wang L, Shi YH, Sui GT, Wu YF, Lu XQ, Li MY, Xia Q, Bian XX, Li HH, Qian JM. Risk factors of acute pancreatitis in the elderly Chinese population: a population-based cross-sectional study. J Dig Dis 2014 Sep;15(9):501-7.

(44) Ali UA, Issa Y, Hagenaars JC, Bakker OJ, van GH, van RB, Besselink MG, Gooszen HG, van Santvoort HC, Boermeester MA. Risk of recurrent pancreatitis and progression to chronic pancreatitis after acute pancreatitis. HPB Conference: 11th World Congress of the International Hepato-Pancreato-Biliary Association Seoul South Korea Conference Publication 2014;16:156.

(45) Ahmed AU, Issa Y, Hagenaars J, Bakker O, van GH, Nieuwenhuijs V, Van EC, Besselink M, Van SH, Boermeester M. Risk of recurrent pancreatitis and progression to chronic pancreatitis after acute pancreatitis. Surgical Infections Conference: 27th European Congress on Surgical Infection Vienna Austria Conference Publication 2014;15(3):A4.

(46) Munigala S, Conwell DL, Gelrud A, Agarwal B. Heavy smoking is associated with lower age at first episode of acute pancreatitis and a higher risk of recurrence. Pancreas 2015;44(6):876-81.

(47) Garg SK, Sarvepalli S, Campbell JP, Obaitan I, Singh D, Bazerbachi F, Singh R, Sanaka MR. Incidence, Admission Rates, and Predictors, and Economic Burden of Adult Emergency Visits for Acute Pancreatitis: Data From the National Emergency Department Sample, 2006 to 2012. J Clin Gastroenterol 2018 Apr 6.

(48) Setiawan VW, Pandol SJ, Porcel J, Wilkens LR, Le ML, Pike MC, Monroe KR. Prospective study of diabetes, smoking, diet and risk of pancreatitis: The multiethnic cohort. Pancreas Conference: 46th Meeting of the American Pancreatic Association San Diego, CA United States Conference Publication 2015;44(8):1413.

(49) Lee Y-K, Huang M-Y, Hsu C-Y, Su Y-C. Bidirectional relationship between diabetes and acute pancreatitis: A population-based cohort study in Taiwan. Medicine (United States) 2016;95(2):e2448.

(50) Girman CJ, Kou TD, Cai B, Alexander CM, O'Neill EA, Williams-Herman DE, Katz L. Patients with type 2 diabetes mellitus have higher risk for acute pancreatitis compared with those without diabetes. Diabetes Obes Metab 2010 Sep;12(9):766-71.

(51) Andriulli A, Botteri E, Almasio PL, Vantini I, Uomo G, Maisonneuve P. Smoking as a cofactor for causation of chronic pancreatitis: a meta-analysis. Pancreas 2010 Nov;39(8):1205-10.

(52) Yuhara H, Ogawa M, Kawaguchi Y, Igarashi M, Mine T. Smoking and risk for acute pancreatitis: a systematic review and meta-analysis. Pancreas 2014 Nov;43(8):1201-7.

(53) Ye X, Lu G, Huai J, Ding J. Impact of smoking on the risk of pancreatitis: a systematic review and meta-analysis. PLoS One 2015;10(4):e0124075.

(54) Sun X, Huang X, Zhao R, Chen B, Xie Q. Meta-analysis: Tobacco smoking may enhance the risk of acute pancreatitis. Pancreatology 2015 May;15(3):286-94.

(55) Lankisch PG, Breuer N, Bruns A, Weber-Dany B, Lowenfels AB, Maisonneuve P. Natural history of acute pancreatitis: A long-term population-based study. American Journal of Gastroenterology 2009;104(11):2797-805.

(56) Amann ST, Yadav D, Barmada MM, O'Connell M, Kennard ED, Anderson M, Baillie J, Sherman S, Romagnuolo J, Hawes RH, Alkaade S, Brand RE, et al. Physical and mental quality of life in chronic pancreatitis: A case-control study from the north american pancreatitis study 2 cohort. Pancreas 2013;42(2):293-300.

(57) Maisonneuve P, Frulloni L, Mullhaupt B, Faitini K, Cavallini G, Lowenfels AB, Ammann RW. Impact of smoking on patients with idiopathic chronic pancreatitis. Pancreas 2006;33(2):163-8.

(58) Pelli H, Lappalainen-Lehto R, Piironen A, Sand J, Nordback I. Risk factors for recurrent acute alcohol-associated pancreatitis: A prospective analysis. Scandinavian Journal of Gastroenterology 2008;43(5):614-21.

(59) Anderson LN, Cotterchio M, Gallinger S. Lifestyle, dietary, and medical history factors associated with pancreatic cancer risk in Ontario, Canada. Cancer Causes and Control 2009;20(6):825-34.

(60) Maisonneuve P, Lowenfels AB, Bueno-de-Mesquita HB, Ghadirian P, Baghurst PA, Zatonski WA, Miller AB, Duell EJ, Boffetta P, Boyle P. Past Medical History and Pancreatic Cancer Risk: Results From a Multicenter Case-Control Study. Annals of Epidemiology 2010;20(2):92-8.

(61) Farrow DC, Davis S. Risk of pancreatic cancer in relation to medical history and the use of tobacco, alcohol and coffee. International Journal of Cancer 45 (5) (pp 816-820), 1990;45(5):816-20.

(62) Talamini G, Bassi C, Falconi M, Sartori N, Vaona B, Bovo P, Benini L, Cavallini G, Pederzoli P, Vantini I. Smoking cessation at the clinical onset of chronic pancreatitis and risk of pancreatic calcifications. Pancreas 2007;35(4):320-6.

(63) Luaces M, Iglesias-Garcia J, Castineira M, Larino-Noia J, Nieto L, Lozano-Leon A, varez-Castro A, Gomez-Casal R, Dominguez-Munoz JE. Factors associated to the severity of chronic pancreatitis at diagnosis: alcohol, tobacco, or both? Pancreatology Conference: 41st European Pancreatic Club (EPC) Meeting Szeged Hungary Conference Publication 2009;9(4):459.

(64) Midha S, Sreenivas V, Chatterjee TK, Kabra M, Joshi YK, Garg PK. Idiopathic chronic pancreatitis, diabetes, and smoking are significant risk factors for pancreatic cancer: Results of case-control and cohort studies. Gastroenterology Conference: Digestive Disease Week, DDW 2010;138(5 (S1)):S551.

(65) Kudo Y, Kamisawa T, Anjiki H, Takuma K, Egawa N. Incidence of and risk factors for developing pancreatic cancer in patients with chronic pancreatitis. Hepato-Gastroenterology 2011;58(106):609-11.

(66) Wu Q, Chen G, Wu W-M, Zhou L, You L, Zhang T-P, Zhao Y-P. Metabolic syndrome components and risk factors for pancreatic adenocarcinoma: A case-control study in China. Digestion 2012;86(4):294-301.

(67) Lucenteforte E, La VC, Silverman D, Petersen GM, Bracci PM, Ji BT, Bosetti C, Li D, Gallinger S, Miller AB, Bueno-de-Mesquita HB, Talamini R, et al. Alcohol consumption and pancreatic cancer: A pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4). Annals of Oncology 2012;23(2):374-82.

(68) Fehringer G, Gallinger S, Borgida A, Zhang LR, Liu G, Hung RJ. Family history of cancers, medical history, and pancreatic cancer risk in the Ontario Pancreatic Cancer Case-Control Study. Cancer Research Conference: 104th Annual Meeting of the American Association for Cancer Research, AACR 2013;DOI: 10.1158/1538-7445.AM2013-4810 Abstract 4810.

(69) Santibanez M, O'Rorke M, O'Leary E, Cantwell M, De Camargo CM, Murray L, Sharp L. Diabetes, pancreatitis and smoking and pancreatic cancer risk: Results from a population-based case-control study in Ireland. Irish Journal of Medical Science Conference: Irish Society of Gastroentrology, Winter Meeting 2014;184(6 Supplement 1):S229.

(70) Lin CC, Chiang JH, Li CI, Hsieh TF, Liu CS, Lin WY, Lee YD, Li TC. Independent and joint effect of type 2 diabetes and gastric and hepatobiliary diseases on risk of pancreatic cancer risk: 10-year follow-up of population-based cohort. British Journal of Cancer 2014;111(11):2180-6.

(71) Luaces-Regueira M, Iglesias-Garcia J, Lindkvist B, Castineira-Alvarino M, Nieto-Garcia L, Larino-Noia J, Dominguez-Munoz JE. Smoking as a risk factor for complications in chronic pancreatitis. Pancreas 2014;43(2):275-80.

(72) Li BR, Pan J, Du TT, Liao Z, Ye B, Zou WB, Chen H, Ji JT, Zheng ZH, Wang D, Lin JH, Ning SB, et al. Risk Factors for Steatorrhea in Chronic Pancreatitis: A Cohort of 2,153 Patients. Scientific reports 2016;6:21381.

(73) Lee JW, Kim HG, Lee DW, Han J, Kwon HY, Seo CJ, Oh JH, Lee JH, Jung JT, Kwon JG, Kim EY. Association between smoking and the progression of computed tomography findings in chronic pancreatitis. Gut and Liver 2016;10(3):464-9.

(74) Midha S, Sreenivas V, Kabra M, Chattopadhyay TK, Joshi YK, Garg PK. Genetically Determined Chronic Pancreatitis but not Alcoholic Pancreatitis Is a Strong Risk Factor for Pancreatic Cancer. Pancreas 2016;45(10):1478-84.

(75) Cho JH, Kim EJ, Choi SH, Kim SY, Kim YJ, Kim YS. Clinical characteristic of hypertriglyceridemia induced acute pancreatitis: A single center study from prospective cohort. Gastroenterology Conference: Digestive Disease Week 2016;150(4 (S1)):S710.

(76) Hao L, Zeng X-P, Xin L, Wang D, Pan J, Bi Y-W, Ji J-T, Du T-T, Lin J-H, Zhang D, Ye B, Zou W-B, et al. Incidence of and risk factors for pancreatic cancer in chronic pancreatitis: A cohort of 1656 patients. Digestive and Liver Disease 2017;49(11):1249-56.

(77) Kim SB, Kim TN, Chung HH, Kim KH. Small Gallstone Size and Delayed Cholecystectomy Increase the Risk of Recurrent Pancreatobiliary Complications After Resolved Acute Biliary Pancreatitis. Digestive Diseases and Sciences 2017;62(3):777-83.

(78) Hao L, Pan J, Wang D, Bi Y-W, Ji J-T, Xin L, Liao Z, Du T-T, Lin J-H, Zhang D, Zeng X-P, Ye B, et al. Risk factors and nomogram for pancreatic pseudocysts in chronic pancreatitis: A cohort of 1998 patients. Journal of Gastroenterology and Hepatology 2017;32(7):1403-11.

(79) Maisonneuve P, Lowenfels AB, Mullhaupt B, Cavallini G, Lankisch PG, Andersen JR, DiMagno EP, ndren-Sandberg A, Domellof L, Frulloni L, Ammann RW. Cigarette smoking accelerates progression of alcoholic chronic pancreatitis. Gut 2005 Apr;54(4):510-4.

(80) Rebours V, Vullierme MP, Hentic O, Maire F, Hammel P, Ruszniewski P, Levy P. Smoking and the course of recurrent acute and chronic alcoholic pancreatitis: a dose-dependent relationship. Pancreas 2012 Nov;41(8):1219-24.

(81) Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, DiMagno EP, ndren-Sandberg A, Domellof L, Di F, V, Pederzoli P, Lohr-Happe A, et al. Prognosis of chronic pancreatitis: An international multicenter study. American Journal of Gastroenterology 89 (9) (pp 1467-1471), 1994;89(9):1467-71.

(82) Suchsland T, Aghdassi A, Kuhn K, Simon P, Lerch MM, Mayerle J, Flessa S. Predictive factors for and incidence of hospital readmissions of patients with acute and chronic pancreatitis. Pancreatology 2015 May;15(3):265-70.

(83) Lee JW, Kim HG, Han J, Kim BS, Jung JT, Kwon JG, Kim EY, Lee CH. Association between smoking and the change of computed tomography findings in chronic pancreatitis. Gastrointestinal Endoscopy Conference: Digestive Diease Week, DDW 2011;April.

(84) Ahmed AU, Issa Y, Hagenaars JC, Bakker OJ, van GH, Nieuwenhuijs VB, Bollen TL, van RB, Witteman BJ, Brink MA, Schaapherder AF, Dejong CH, et al. Risk of Recurrent Pancreatitis and Progression to Chronic Pancreatitis After a First Episode of Acute Pancreatitis. Clin Gastroenterol Hepatol 2016 May;14(5):738-46.

(85) Xiang JX, Hu LS, Liu P, Tian BY, Su Q, Ji YC, Zhang XF, Liu XM, Wu Z, Lv Y. Impact of cigarette smoking on recurrence of hyperlipidemic acute pancreatitis. World J Gastroenterol 2017 Dec 21;23(47):8387-94.

(86) Truninger K. [Risk groups for pancreatic and bile duct carcinomas]. Praxis (Bern 1994 ) 2000 Aug 17;89(33):1299-304.

(87) Chowdhury P, Rayford PL. Smoking and pancreatic disorders. Eur J Gastroenterol Hepatol 2000 Aug;12(8):869-77.

(88) DiMagno MJ, DiMagno EP. Chronic pancreatitis. Curr Opin Gastroenterol 2005 Sep;21(5):544-54.

(89) Nair RJ, Lawler L, Miller MR. Chronic pancreatitis. Am Fam Physician 2007 Dec 1;76(11):1679-88.

(90) Otsuki M, Tashiro M. 4. Chronic pancreatitis and pancreatic cancer, lifestyle-related diseases. Intern Med 2007;46(2):109-13.

(91) Yadav D, Whitcomb DC. The role of alcohol and smoking in pancreatitis. Nat Rev Gastroenterol Hepatol 2010 Mar;7(3):131-45.

(92) Jupp J, Fine D, Johnson CD. The epidemiology and socioeconomic impact of chronic pancreatitis. Best Pract Res Clin Gastroenterol 2010 Jun;24(3):219-31.

(93) Alsamarrai A, Das SL, Windsor JA, Petrov MS. Factors that affect risk for pancreatic disease in the general population: a systematic review and meta-analysis of prospective cohort studies. Clin Gastroenterol Hepatol 2014 Oct;12(10):1635-44.

(94) Kleeff J, Whitcomb DC, Shimosegawa T, Esposito I, Lerch MM, Gress T, Mayerle J, Drewes AM, Rebours V, Akisik F, Munoz JED, Neoptolemos JP. Chronic pancreatitis. Nat Rev Dis Primers 2017 Sep 7;3:17060.

Supplementary Table 2. Study quality of the included studies ( Newcastle-Ottawa scale)

Author, publication year

Representative-ness

Selection of non-exposed cohort

Exposure ascertainment

Demonstration of outcome not present at start

Adjustment for one confounder

Adjustment for a second confounder

Assessment of outcome

Long enough follow-up

Loss to follow-up

Total

Morton, 2004 1 1 0 1 1 1 1 1 0 7

Lindkvist, 2008 1 1 0 1 1 1 1 1 0 7

Tolstrup, 2009 1 1 0 1 1 1 1 1 1 8

Gonzalez-Perez, 2010

1 1 0 1 1 1 1 1 0 7

Sadr-Azodi, 2013 1 1 0 1 1 1 1 1 0 7

Lin, 2014 1 1 1 1 1 1 1 1 0 8

Prizment, 2015 1 1 0 0 1 1 1 1 1 7

Setiawan, 2016 0 1 0 1 1 1 1 1 0 6

Pang, 2018 1 1 0 1 1 1 1 1 1 8

Supplementary Figure 1. Funnel plot of current smoking and acute pancreatitis

0.0

5.1

.15

.2s.

e. o

f log

rr

0 .2 .4 .6 .8logrr

Funnel plot with pseudo 95% confidence limits

Supplementary Figure 2. Funnel plot of former smoking and acute pancreatitis

0.1

.2.3

s.e.

of l

ogrr

-.5 0 .5 1logrr


Supplementary Figure 3. Funnel plot of ever smoking and acute pancreatitis

0.0

5.1

.15

.2s.

e. o

f log

rr

0 .2 .4 .6 .8logrr


Supplementary Figure 4. Sensitivity analysis excluding one study at a time for current smoking and acute pancreatitis

1.25 1.49 1.29 1.72 1.84

Pang, 2018

Setiawan, 2016

Prizment, 2015

Sadr-Azodi, 2012


Tolstrup, 2009

Lindkvist, 2008

Study ommited Meta-analysis random-effects estimates (exponential form)

------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Pang, 2018 | 1.5225949 1.2586498 1.8418906 Setiawan, 2016 | 1.5235339 1.2624158 1.8386619 Prizment, 2015 | 1.5498899 1.3856829 1.7335558 Sadr-Azodi, 2012 | 1.5025785 1.2608072 1.7907119 Gonzalez-Perez, 2010| 1.4979715 1.2787821 1.7547311 Tolstrup, 2009 | 1.4313016 1.2556105 1.6315762 Lindkvist, 2008 | 1.4338214 1.2506742 1.6437885-------------------+---------------------------------------------------------- Combined | 1.4913201 1.2937507 1.7190605------------------------------------------------------------------------------

Supplementary Figure 5. Sensitivity analysis excluding one study at a time for former smoking and acute pancreatitis

1.09 1.24 1.15 1.34 1.41

Pang, 2018

Setiawan, 2016

Prizment, 2015

Sadr-Azodi, 2012


Tolstrup, 2009

Lindkvist, 2008



Supplementary Figure 6. Sensitivity analysis excluding one study at a time for ever smoking and acute pancreatitis

1.21 1.39 1.25 1.54 1.64

Pang, 2018

Setiawan, 2016

Prizment, 2015

Sadr-Azodi, 2012


Tolstrup, 2009

Lindkvist, 2008



Supplementary Figure 7. Sensitivity analysis excluding one study at a time for current smoking and chronic pancreatitis

1.32 1.93 1.60 2.32 2.50

Pang, 2018

Setiawan, 2016

Prizment, 2015

Tolstrup, 2009


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Pang, 2018 | 1.9409943 1.6060915 2.3457310 Setiawan, 2016 | 1.7448012 1.3224186 2.3020935 Prizment, 2015 | 2.0221403 1.6362270 2.4990735 Tolstrup, 2009 | 1.9286803 1.5703496 2.3687768-------------------+---------------------------------------------------------- Combined | 1.9270934 1.6002703 2.3206635------------------------------------------------------------------------------

Supplementary Figure 8. Sensitivity analysis excluding one study at a time for former smoking and chronic pancreatitis

0.79 1.30 1.08 1.57 2.23

Setiawan, 2016

Prizment, 2015

Tolstrup, 2009


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Setiawan, 2016 | 1.3265351 0.78897572 2.2303541 Prizment, 2015 | 1.2410346 1.00768670 1.5284184 Tolstrup, 2009 | 1.3260264 1.09238860 1.6096343-------------------+---------------------------------------------------------- Combined | 1.2981466 1.07519910 1.5673233------------------------------------------------------------------------------

Supplementary Figure 9. Sensitivity analysis excluding one study at a time for ever smoking and chronic pancreatitis

1.28 1.59 1.39 1.82 2.04

Setiawan, 2016

Prizment, 2015

Tolstrup, 2009


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Setiawan, 2016 | 1.6200000 1.2840424 2.0438578 Prizment, 2015 | 1.5776975 1.3557831 1.8359348 Tolstrup, 2009 | 1.5819548 1.3702604 1.8263546-------------------+---------------------------------------------------------- Combined | 1.5865819 1.3868547 1.8150728------------------------------------------------------------------------------

Supplementary Figure 10. Funnel plot of current smoking and total pancreatitis

0.1

.2.3

s.e.

of l

ogrr

-.5 0 .5 1logrr


Supplementary Figure 11. Sensitivity analysis excluding one study at a time for current smoking and total pancreatitis

1.19 1.62 1.29 2.03 2.30

Pang, 2018

Setiawan, 2016

Prizment, 2015

Lin, 2014

Tolstrup, 2009

Morton, 2004


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Pang, 2018 | 1.6549585 1.1903387 2.3009312 Setiawan, 2016 | 1.6485760 1.2315691 2.2067807 Prizment, 2015 | 1.7517918 1.3661946 2.2462206 Lin, 2014 | 1.6761312 1.3195612 2.1290531 Tolstrup, 2009 | 1.5217673 1.2030087 1.9249866 Morton, 2004 | 1.4712266 1.2259645 1.7655549-------------------+---------------------------------------------------------- Combined | 1.6200802 1.2925920 2.0305401------------------------------------------------------------------------------

Supplementary Figure 12. Sensitivity analysis excluding one study at a time for former smoking and total pancreatitis

1.13 1.29 1.16 1.43 1.62

Setiawan, 2016

Prizment, 2015

Tolstrup, 2009

Morton, 2004


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Setiawan, 2016 | 1.3760266 1.1707975 1.6172304 Prizment, 2015 | 1.2729800 1.1266270 1.4383447 Tolstrup, 2009 | 1.2687485 1.1371661 1.4155563 Morton, 2004 | 1.2726209 1.1326152 1.4299332-------------------+---------------------------------------------------------- Combined | 1.2860739 1.1556585 1.4312067------------------------------------------------------------------------------

Supplementary Figure 13. Sensitivity analysis excluding one study at a time for ever smoking and total pancreatitis

1.14 1.58 1.24 2.02 2.43

Setiawan, 2016

Prizment, 2015

Tolstrup, 2009

Morton, 2004


------------------------------------------------------------------------------ Study omitted | e^coef. [95% Conf. Interval]-------------------+---------------------------------------------------------- Setiawan, 2016 | 1.6977843 1.1837760 2.4349806 Prizment, 2015 | 1.7359568 1.2636800 2.3847382 Tolstrup, 2009 | 1.4555100 1.1352201 1.8661664 Morton, 2004 | 1.4639460 1.1481141 1.8666594-------------------+---------------------------------------------------------- Combined | 1.5801335 1.2388396 2.015452------------------------------------------------------------------------------

Supplementary Figure 14. Current smoking and gallstone-related and non-gallstone-related pancreatitis

Relative Risk .25 .5 .75 1 1.5 2 3 5

Study Relative Risk (95% CI)

Gallstone-related pancreatitis

Setiawan, 2016 1.10 ( 0.89, 1.35)

Sadr-Azodi, 2012 0.88 ( 0.70, 1.29)

Morton, 2004 1.10 ( 0.56, 2.15)

Subtotal 1.03 ( 0.87, 1.22)

Non-gallstone-related pancreatitis

Setiawan, 2016 1.73 ( 1.46, 2.05)

Sadr-Azodi, 2012 1.83 ( 1.37, 2.44)

Morton, 2004 2.68 ( 1.93, 3.73)

Subtotal 1.98 ( 1.55, 2.53)

Supplementary Figure 15. Former smoking and gallstone-related and non-gallstone-related pancreatitis

Relative Risk .25 .5 .75 1 1.5 2 3 5



Setiawan, 2016 1.19 ( 1.03, 1.37)

Sadr-Azodi, 2012 0.95 ( 0.62, 1.26)

Morton, 2004 1.20 ( 0.70, 2.20)

Subtotal 1.16 ( 1.02, 1.31)


Setiawan, 2016 1.29 ( 1.13, 1.49)

Sadr-Azodi, 2012 1.47 ( 1.11, 1.94)

Morton, 2004 1.81 ( 1.20, 2.73)

Subtotal 1.40 ( 1.19, 1.64)

Supplementary Figure 16. Ever smoking and gallstone-related and non-gallstone-related pancreatitis

Relative Risk .25 .5 .75 1 1.5 2 3 5



Setiawan, 2016 1.16 ( 1.03, 1.31)

Sadr-Azodi, 2012 0.91 ( 0.72, 1.15)

Morton, 2004 1.16 ( 0.75, 1.79)

Subtotal 1.08 ( 0.91, 1.27)


Setiawan, 2016 1.45 ( 1.30, 1.61)

Sadr-Azodi, 2012 1.63 ( 1.34, 2.00)

Morton, 2004 2.30 ( 1.78, 2.97)

Subtotal 1.72 ( 1.35, 2.20)

ars.els-cdn.com · Web view(67) Lucenteforte E, La VC, Silverman D, Petersen GM, Bracci PM, Ji BT,...

Documents

Transcript of ars.els-cdn.com · Web view(67) Lucenteforte E, La VC, Silverman D, Petersen GM, Bracci PM, Ji BT,...