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Transcript of Arkhangelsk(Dentists) - UiTArkhangelsk regional clinical dental polyclinic}Arkhangelsk regional...
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Antimicrobial stewardship in dental practice
Dr. Alina Bogomolova, Maxillofacial surgeon, Arkhangelsk Regional Clinical Hospital, Russia
ArkhangelskRegionalClinicalHospital
Arkhangelskregionalclinicaldentalpolyclinic
} Arkhangelskregionalclinicaldentalpolyclinicconsistsofthemainbuildingand2branches.Alltypesofdentalaidarerepresentedintheclinicexceptpedodontics.Therearedentaltherapy,oralsurgeryandprostheticdepartments.Alsotherearespecialistsintreatmentofthediseasesoforalmucosaandprophylaxisoforaldiseases.InadditiontothemedicalaidtheclinicistheeducationalbaseforstudentsoftheNSMU.
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Background
-Antibioticresistanceisaseriousproblemforpatientsandhealthsystemsbecauseinfectionscausedbyantibiotic-resistantbacteriacanleadtohigherratesofillnessanddeath.-Resistancetoantibacterialmedicinesoftenoccursbecauseantibioticsareusedwhentheyarenotneeded.
- Antibioticsareusedtotreatbacterialinfectionsindentalpracticealso.Manybacteriahavebecomeresistanttoantibioticsovertime.
Aimofthestudy
Toanalyzeusingofantibioticsindentalpractice bydentistsofvariousspecialtiesintheCircumpolarRegion
MethodsandmaterialsThisstudywasconductedduringMarch2018. Atotalof63dentistsofvariousspecialties(dentists,oralsurgeons,maxillofacialsurgeons),whovolunteeredforthisstudy,wasinterviewed byquestionnaireinRussian,whichwasdesignedbyresearchersthemselves.Thequestionnairehadthreesections.Thefirstpresentedsocialstatusofrespondents,thesecondsectionanalyzed tacticsoftreatment andthethirdsectionassessedtheknowledgeoftherespondentsaboutantibioticprescribingpractices.
Sample ofthestudy
33,9%
64,4%
1,7%
Belongingtoamedicalorganization
Private clinic State clinic University clinic
28,8%
71,2%
Distributionbygender
Male Female
23,8%
36,5%
25,4%
9,5%
4,8%
Distributionbyage
20-24 y.o.
25-29 y.o.
30-39 y.o.
40-49 y.o.
> 50 y.o.
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Sample ofthestudyDentalspecialty
45,80%
25,40%
16,90%
11,90%General practice dentist
Dental therapist
Oral surgeon
Maxillofacial surgeon
43,3%
18,3%5,1%
14,0%
10,0%
8,3%
Seniorityinspecialty
1-2 years 3-5 years
6-9 years 10-14 years
15-20 years > 20 years
Resultsofthestudy
GuideforprescribingantibioticsTrainingprogramRecommendationsofexperiencedcolleaguesRecommendationsofpharmacistDatafrommedicalliteratureOwnexperienceoftreatmentAdvertisementofmedicinesOthers
23 (37,1%)7 (11,3%)
13 (21%)
11 (17,7%)7 (11,3%)
3 (4,8%)
0 5 10 15 20 25
University program
Internship
Residency
Training program
Thematic seminars
Never
Trainingforprescribingantibiotics
Resultsofthestudy
Dentistry MaxillofacialSurgery
Therapeuticdentistry
Diffuseinflammation
Acutepurulentperiostitis
Acuteulcerativegingivitis
Lymphadenitis Fractureofthemandible
Acuteperiapicalprocess
Afever withcommonsymptomsofinflammation
Phlegmones andabscessesofthemaxillofacialarea
Chronicperiodontitis intheacutestage
Antibiotictreatmentisnecessary
Resultsofthestudy} Non-clinicalfactorsrequiringantibioticsprescribing} Preventionofinflammatorycomplicationsbeforesurgery} Deferredtreatment
} Dentalinterventionsrequiringprescriptionofantibacterialmedicaments
} Complicatedtoothextraction} Dentalimplantation} Endodontictreatment(inthepresenceofcomplications)
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Resultsofthestudy
Highrisk ofspreadofinfection
Moderaterisk ofspreadofinfection
Lowrisk ofspreadofinfection
Infectiousendocarditisinanamnesis (64,5%)
HIV/AIDS (28,3%) Presenceofapacemaker(23,7%)
HIV/AIDS (48,4%) Infectiousendocarditis inanamnesis (26,7%)
HIV/AIDS (22%)
Patientsonimmunosuppressivetherapy (38,7%)
Patientsonimmunosuppressivetherapy (23,3%)
Patientswithdifferenttransplants(23.3%)
Coronaryarterybypassgraft(20,3%)
Compliantdiseasesofpatientsrequiring theprescriptionofantibioticsResultsofthestudy} Antibacterialmedicinesthatshouldbeusedwithaprovenallergytopenicillinantibiotics} Modernmacrolides (57,4%)} Cephalosporins 3-5generations (31,1%)} Lincosamides (27,9%)} Fluoroquinolones (27,9%)} Cephalosporins 1-2 generations (8,2%)} Vancomycin (8,2%)} Carbapenems (6,6%)} Difficulttoanswer (21,3%)
ResultsofthestudyPatientswhichhaveahighriskofantibioticresistance
Intakeofanantibioticinthelast3monthsIntakeofanantibioticwithinthelast6monthsPresenceofinfectiousdiseasesDiabetesCardiovasculardiseasesSurgicalinterventions(operations)carriedoverthelast3monthsDifficulttoanswer
Resultsofthestudy
Penicillins Macrolides Fluoroquinolones
Dyspepticphenomena(72,1%)
Dyspepticphenomena(46,7%)
Neurotoxicity(52,5%)
Fungaldiseases(37,7%)
Difficulttoanswer(38,3%)
Fungaldiseases(40,7%)
Hepatotoxicity(27,9%)
Hepatotoxicity(33,3%)
Difficulttoanswer(40,7%)
Sideeffects
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Resultsofthestudy} Thedurationofantibiotictherapy
} 5-7days (68,9%)} alwaysdifferent (19,7%)} 7-10 days (16,4%)
} Theneedformicrobiologicalanalysis} iftheinitialantibacterialtherapyisineffective (55,7%)} Always (32,8%)
Resultsofthestudy} Antibacterialtherapyisineffective
} nopositivedynamicsduring48hours (47,5%)} nopositivedynamicsduring72 hours (39,3%)} nopositivedynamicsduring24 hours (11,5%)
} Actionsiftheinitialantibacterialtherapyisineffective} Changethestartingantibiotictoamedicineofanothergroup (63,9%)
ResultsofthestudyCombinationsofantimicrobialmedicines
Fluoroquinolonesandnitrofurans
Penicillins andaminoglycosides
Penicillins andpenicillins
Aminoglycosidesandaminoglycosides
Cephalosporins andmetronidazole
Сephalosporins andfluoroquinolones
Difficulttoanswer
Conclusions} Theeducationinprescriptionofantibacterialmedicinesisincludedintheuniversityprogram,inpostgraduateperiodknowledgebecomefragmental
} Generalpracticedentistsprescribeantibiotics(accordingtoobtaineddata)incasesofdiffuseinflammation,lymphadenitis,feverwithcommonsymptomsofinflammation.Dentaltherapists– incaseofacuteulcerativegingivitis,acuteperiapicalprocess,chronicperiodontitisintheacutestage.Maxillofacialsurgeonsassumethatantibioticsshouldbegivenincaseofacutepurulentperiostitis,fractureofthemandible,phlegmones andabscessesofthemaxillofacialarea
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} Questionsrelatedtogroupsofantibacterialmedicines,theircombinationsandsideeffectscausedthemostofdifficultiesinanswering
} Practicingdentistsgobymedicalliteraturedataandrecommendationsofthemoreexperiencedcolleaguestouseantibioticsintheirdailywork
} Inaccordancewithobtaineddata,wecandeducethatthereisaneedfordevelopmentofunifiedclinicalrecommendationsinantibioticsprescription
Thank you for attention!