Are your hormones making you sick
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Transcript of Are your hormones making you sick
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Are Your Hormones Making
You Sick ?Presented by
Eldred B. Taylor, M.D.
Medical Director of the Taylor Medical Group
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Don’t Be ACaterpillar
Get Out of Line
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Women’s WisdomWomen have an innate sense
of spirituality an ability to attune to the wisdom within themselves and the larger
whole that has been systematically ignored by
medicine Joan Borysensko, Ph.D.Author of Minding the Body Mending the Mind
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Goals
Become an Honorary Gynecologist
Be able to diagnose yourself Amaze your friends and
family Identify and avoid all
caterpillar lines
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Women in the U.S.
80% of women complain of PMS
20%-50% of women have fibroids
80%-90% complain of perimenopausal symptoms
Premenopausal breast cancer has increased by 30% in the last 30 years
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Women in the U.S.
90 % of women have menopausal symptoms
Osteoporosis effects more than 45% of women over age 50
Hysterectomy and breast surgery are the most common surgeries done in most hospitals
Heart disease and breast cancer
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What is normal?
Cycles
Balance
Transiti
ons
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The Menstrual Cycle
Estrogen = GrowProgesterone=Develop
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The Menstrual Cycle
Estrogen is dominant the first two weeks
Progesterone should be dominant the second two weeks
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E/P Ratio in theMenstrual Cycle
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What is estrogen?
Phytoestrogens-Plant estrogen
Estriol-highest amount in pregnancy
Estrone-made in fat tissue Estradiol- made by the
ovary Xenoestrogens-Man made
estrogen
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What is the function of estrogen?
Regrowth of menstrual tissue
Growth of follicle into an egg
Growth of breast
Support vaginal tissue
Develop sex characteristics
Stores Fat Decreases
thyroid hormone
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What is Progesterone?
Progesterone-made by the ovary after ovulation
Progesterone-can be made from wild yam and soy beans
Provera and Depo Provera-Are not progesterone
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Functions of Progesterone
Pro-Gestation Natural Diuretic Uses fat for energy Natural
antidepressant Restores sex drive Protects against
cancer
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This Is Biochemisty
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Bio-Identical
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What is Premarin? Pregnant Mare Urine
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Effects of Progestins(Provera) Secretory endometrium No positive effects on gestation,
teratogenicCreates progesterone
deficiency Increases sodium and water
retention Depression Weight gain Hair loss Increased risk of breast cancer
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Balance Of Actions
The ultimate biologic response reflects the Balance of Actions of the different hormones with their respective receptors…
Speroff L, Glass R, Kase N. Clinical Gynecologic Endocrinology and Infertility. 7th Edition, Lippincott Williams and Wilkins, Baltimore, MD, 2005, Pg. 61
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Excess Estrogen Causes
Breast tenderness
Depression,Fatigue, Poor concentration
Endometriosis Fibrocystic
breasts PMS
Fibroids Water
retention and bloating
Fat gain around hips and thighs
Breast and Uterinecancer
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Progesterone Deficiency Cause?
Breast tenderness
Depression,Fatigue, Poor concentration
Endometriosis Fibrocystic
breasts PMS
Fibroids Water
retention and bloating
Fat gain around hips and thighs
Breast and Uterinecancer
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How Do You Measure Balance?
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Gynecology Made Simple
Key Question How Old Are You? < 45…….Birth Control Pills > 45…….Hormone
Replacement < or > 45 …..Antidepressant No response to
therapy…….Surgery
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How Do I Know If I’m Out of Balance?
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Salivary Testing -Oil and Water
Oil and water don’t mix Measures the packages that are
delivered Accurately diagnoses hormone
imbalances Allows the doctor to monitor
hormone levels
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What Increases Delivery
Excess weight Low fiber diet Stress Insulin/carbohydrates Provera Male hormones
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Other Factors That Effect Balance
Poor Diet Sedentary Lifestyle
External Estrogen Delayed Childbearing Alcohol Abuse
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What Are the Results of This Hormonal
Imbalance? PMS
Fibroids
Endometriosis/Infertility
Fibrocystic Breast
Perimenopause
Menopause
Osteoporosis
Breast, uterine and ovarian cancer
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PMS-Premenstrual Syndrome
68%-100% complain of:
Tension Nervousness
Anxiety IrritabilityMood Swings
44%-55% complain of:
Sweet CravingsHeadaches Increased
Appetite36% complain of: DepressionConfusionCryingForgetfulness
60%-65% complain of :
Weight gainAbdominal
bloatingBreast tendernessSwelling of
extremities
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E/P Ratio in theMenstrual Cycle
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What are fibroids?
Non-cancerous tumors in the uterus
Occurs after age 30 Growth stimulated by
decliningprogesterone
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What Is Endometriosis?
Uterine tissue outside the uterus
Causes cyclic pain Painful menses
Infertility
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Fibrocystic Breast
Caused by overstimulation of estrogen
Estrogen causes increased cell growth
Estrogen causes swelling
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What is perimenopause ?
Begins 10-15 years prior to menopause
Erratic hormone production Annovulatory Cycles Increasing estrogen Declining progesterone
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Perimenopausal Symptoms
Menstrual Irregularities Estrogen Excess Symptoms Initiation of bone loss Growth of fibroids Increased cancer risk
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Eggs and Age
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Menstrual Irregularities
Missed Periods Heavy Bleeding Prolonged
Menses–Cause- Fewer eggs, no ovulation, no progesterone,
–Progesterone is the menstrual timekeeper
Estrogen Excess Symptoms
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What Is Menopause?
Permanent cessation of menstruation
Caused by decreased production of ovarian hormones
Most commonly occurs between ages of 48-52
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Significant Estrogen in Menopause
Speroff L, Glass R, Kase N. Clinical Gynecologic Endocrinology and Infertility. 7th Edition, Lippincott Williams and Wilkins, Baltimore, MD, 2005, Pg. 636
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Menopausal
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Cancer-Uncontrolled Growth
Estrogen increases cell growth
Progesterone increases normal development and slows cell growth
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Breast Cancer Detection
Speroff L, Glass R, Kase N. Clinical Gynecologic Endocrinology and Infertility. 7th Edition, Lippincott Williams and Wilkins, Baltimore, MD, 2005, Pg. 610
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Breast Cancer Incidence and Death…
About 40,170 women will die from breast cancer each year
In the United States, DCIS incidence rose from 1.87 per 100 000 in 1973-1975 to 32.5 in 2004.
• Breast cancer is the second leading cause of death in women ages 20-59.• It is estimated one in every 8 women will be diagnosed with breast cancer in their
lifetime.• 8 out of 9 women who develop breast cancer have no family history.
• In the United States a new breast cancer diagnosis occurs every 3 minutes.• Approximately 192,370 new cases of invasive breast cancer were diagnosed in 2009• Approximately 62,280 new cases of carcinoma in situ (CIS) were diagnosed (CIS is non-
invasive and is the earliest form of breast cancer) in 2009.
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New or Old Theory?Louis Pasteur
1895“The cell is nothing, the matrix is everything”
Old Ideas Spur New Approaches in Cancer FightNew York Times article December 29, 2009
“The new focus on a cancer’s surroundings, researchers say is a major shift in thinking about why
cancer occurs and how to stop it”
Mary Claire King and BRCA 1 and 2 “The lifetime risk of breast cancer among female mutation
carriers is presently 82%. Risks appear to be increasing with time. Before 1940 it was 24%. Lack of physical exercise and obesity in adolescence may be important modulating factors
for risk in carriers”. Science 2003; 302: 643‐50.
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Decrease in Breast Cancerafter WHI
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Initial Thermogram
Thermogram 30 days post application of Cream
PtJG
50 patients enrolled to access the effect of transdermal synergistic cream on breasts using sequential thermography.
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Indications for Estrogen
High risk for osteoporosis
Symptoms of menopause
That’s it !
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Dr. Taylor’sIndications for EstrogenSalivary testing that
indicates a deficiency
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Dietary Changes Organic fruits and vegetables Increase fiber Omega 3 and 9 fatty acids Low glycemic index foods Decrease animal protein Organic or hormone free meats Increase plant protein-Soy, and
other beans
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Lifestyle Changes
Increase activityReduce stress- Prayer &Meditation
Consider career changes
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Supplements
Whole FoodsVitamin B complex-150
mg/dayFolic acid 1mg/dayMagnesium, vitamin D,
Boron 2mg
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Hormonal Choices:Estrogenic
Bio-identical estrogens Biest
–Estriol 2mg, Estradiol .5mg Triest
–Estriol 2mg, Estradiol .25mg, Estrone .25mg
Produced by compounding pharmacies
Estrace, Climara, Alora
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Hormonal Choices:Estrogenic
Black Cohash-Remifemin–Well studied in Germany–Effective for menopausal
symptom relief–not estrogenic
Red clover-Promensil–contains plant estrogens–2 unpublished studies revealed
not effective for hot flashes as compared to placebo
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Hormonal Choices: Progestogenic
Micronized Progesterone ( cream or oral)–Bioavailable, safe, prescription –Effective from puberty throughout
life–20mg-40mg/ day cream 100mg-
200 mg oral–Maintains or increases quality of
life–No disruptive side effects–No increased cancer risks or heart
disease–May help prevent degenerative
diseases
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Goals Become an Honorary
Gynecologist Be able to diagnose yourself Amaze your friends and
family Identify and avoid all
caterpillar lines
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Don’t Be A Caterpillar
Get out of line
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Other Hormones that May Make You Sick