ARCS® Foundation, Inc., San Diego Chapter

44

Transcript of ARCS® Foundation, Inc., San Diego Chapter

Page 1: ARCS® Foundation, Inc., San Diego Chapter
Page 2: ARCS® Foundation, Inc., San Diego Chapter

“We're extremely grateful to the ARCS Foundation for theirpartnership and support of our students. Working together, we canhelp develop the scientists and engineers who will lead ourcountry's future scientific and economic development.”

Elliot Hirshman, PresidentSan Diego State University

“ARCS does an extraordinary job of funding and promoting scienceeducation in our community. By supporting the most talented andinnovative students, ARCS helps San Diego lead the charge increating new therapies to combat disease and improve humanhealth. TSRI is grateful for the ARCS Foundation’s long-standingsupport of the scientific community in San Diego.”

Dr. Steve Kay, President The Scripps Research Institute

"ARCS Scholar awards provide UC San Diego graduate and doctoralstudents with vital support for their research in the sciences,engineering and medical fields. We are most grateful to the ARCSFoundation for its partnership in educating our future scientists,educators, innovators and leaders."

Pradeep K. Khosla, ChancellorUniversity of California, San Diego

ARCS’ tradition of generous philanthropic support fosters excellentscience and healthcare education. It not only encourages some of themost talented and deserving students at the University of San Diego,but it also strengthens related professions and enhances the quality oflife for all of us in the region and beyond. We remain very grateful forthe enthusiastic expression of confidence and affirmation that eachARCS’ gift represents.

James T. Harris III, D.Ed., PresidentUniversity of San Diego

Words from University Presidents

Page 3: ARCS® Foundation, Inc., San Diego Chapter

1

Words from Our PresidentThe beginning of the academic school year is always filled with hopes and expectations for

what lies ahead in the coming year. It is also the time for the San Diego Chapter of ARCS

Foundation, Inc., to present to our recipient universities the checks that have been allocated

for the Scholars they have selected. It is awe-inspiring to see Scholars so committed to their

field of studies and so full of promise for the future. Though it is the beginning of a new

year for our Scholars, it is the culmination of the hard work and generous spirit of our ARCS

members, friends, and faithful donors from the previous year.

As all viable and enduring organizations must, ARCS Foundation has evolved from those early days of

Sputnik and the Cold War. The enemy, real and imagined, no longer fuels our fear and sense of urgency to

respond to crisis. Instead there is the realization that we are the women who are to nourish and support

financially these Scholars who have been chosen by their universities as showing the greatest promise for

good. As you read through this directory, take time to note the various fields of study. You will find them

addressing the greatest problems of our time: disease, degradation of our environment, building machinery

and structures, understanding our brain and how it works. The ideas are endless and only limited by our

lack of imagination.

Into this paradigm of the Scholars, the universities, and the ARCS Foundation, there seems to be another

entity appearing: a merging of business and industry with our goals, providing opportunity for our finished

product of disciplined, knowledgeable, and enthusiastic people ready to bring their talents to the

marketplace. Let’s watch to see how it matures.

As for me, I’m grabbing onto their coat tails, enjoying the ride, and hanging on for dear LIFE.

Mary Fitz, President, San Diego Chapter

ARCS Foundation, Inc.

ARCS San Diego ChapterBoard of Directors

2015-2016

President ........................................................................................................................................................ Mary Fitz

Immediate Past President .................................................................................................... Diane Annala Chalmers

Vice Presidents:Administration ..................................................................................................................................... Helga MooreCommunications ............................................................................................................................ Mary Lou QuickFund Development .................................................................................................................................. Joy KirschMembership .................................................................................................................................. Sharon ArbelaezMeetings & Special Events ............................................................................................................... Marge HebertUniversity Relations ............................................................................................................................. Alice Brown Finance ............................................................................................................................................Tanya Schierling

Recording Secretary .............................................................................................................................. Sue Pondrom

Parliamentarian....................................................................................................................................... Peggy Hanley

Members-at-Large ................................................................................................. Dottie Georgens, Linda Johnson

Page 4: ARCS® Foundation, Inc., San Diego Chapter

2

ARCS® Scholars 2015-2016NAME DEGREE AREA OF CONCENTRATION SPECIALIZATION

Vincent Berardi Ph.D. Computational Science Computational Human Behavior

Peter Calhoun Ph.D. Statistics Random Forests

Daniel Cuevas Ph.D. Computational Biology Genomics and Bioinformatics

David Curran M.S. Mechanical Engineering Heat Transfer and Solar Power

Bryan Hancock Ph.D. Microbiology, cell signaling, Host-Pathogen Interactionsand molecular biology

Sean Maddox Ph.D. Chemistry Organic Catalysis

Paul Maier Ph.D. Evolutionary Biology Genomics of Adaptation and Specialization

Megan Monsanto Ph.D. Cell and Molecular Biology Cardiac Stem Cell Biology

Tim Montgomery Ph.D. Organic Chemistry Green Organic Chemistry Synthesis

Erik Paulson Ph.D. Chemistry Bifunctional Catalysis

Stephen Rice Ph.D. Evolutionary Biology Conservation Genetics/Genomics, Climate Change

Kelly Ross Ph.D. Cell/Molecular Biology Regenerative Medicine Research

Julia Rossi Ph.D. Computational Science Computational Physics

Colette Smirniotis Ph.D. Statistics Data Assimilation

Winston Stauffer Ph.D. Cell and Molecular Biology Cardiology

Jessica Bruhn Ph.D. Biological Sciences Structural Virology

George Campbell Ph.D. Cell & Molecular Biology Neurodegenerative Disease

Rigo Cintron-Colon Ph.D. Chemical Physiology & Physiology of ThermoregulationMolecular and Cellular Neuroscience

Danielle Grotjahn Ph.D. Biomedical Sciences Cell and Molecular Biology

Margarete Johnson Ph.D. Biology Immunology

John Tat Ph.D. Cell and Molecular Biology; Cell Cycle Regulation, Cancer TherapeuticsMolecular Pharmacotherapeutics

Lisa Alvarez Ph.D. Nursing Sciences Cardiology

Dinnah Didulo Ph.D. Nursing Sciences High Risk Populations

Lauren Hoffman B.A./B.S. Mechanical Engineering Water Systems

Deanna Johnston Ph.D. Nursing Sciences Adult Health, Gerontology and Palliative Care

Monique Lineback Ph.D. Nursing Sciences Health Promotion

Anthony Shao B.S. Electrical Engineering Circuits

Page 5: ARCS® Foundation, Inc., San Diego Chapter

3

NAME DEGREE AREA OF CONCENTRATION SPECIALIZATION

Grant Allen Ph.D. Quantum Information Entanglement Monogamy

Laura Andersen Ph.D. Materials Science & Engineering Metallurgy, Bulk Metallic Glasses

Russell Chan Ph.D. Biochemistry RNA Structural Biology

Michelle Chen Ph.D. Structural Engineering Seismic Performance & Isolation

Monica Chu Ph.D. Neurobiology Systems Neurobiology

Christopher DeBoever Ph.D. Bioinformatics & Systems Biology Genetics and Genomics

Edward Dechaumphai Ph.D. Mechanical engineering Thermal Engineering/Design

Michael Denny Ph.D. Chemistry Inorganic Chemistry

Igor Fedorov Ph.D. Electrical Engineering Machine Learning and Signal Processing

Danielle Hagstrom Ph.D. Cellular and Developmental Biology Developmental Neurotoxicology

Daniel Hoff Ph.D. Mathematics Von Neumann Algebras

Eiren Jacobson Ph.D. Oceanography Biological Oceanography

Maggie Johnson Ph.D. Oceanography Marine Biology

Trevor Joyce Ph.D. Biological Oceanography Marine Predator Conservation

Ashok Kodigala Ph.D. Nano-Photonics Plasmonics and Semiconductor Lasers

Aditya Kumar Ph.D. Bioengineering Stem Cells, Heart Disease

David Leon Ph.D. Physics Cosmology

Frederick Matsuda Ph.D. Physics Astrophysics and Cosmology

Steven Naleway Ph.D. Materials Science and Engineering Biological Materials and Bioinspired Design

Emily Nardoni Ph.D. Physics High Energy Theory

David Nelles Ph.D. Bioengineering Biomolecular Engineering

Julia Nussbacher Ph.D. Biomedical Sciences RNA Biology

Timothy O'Connor Ph.D. Applied Physics and NanoEngineering Stretchable/Wearable Electronics, SolarEnergy, Bio-Integrated Devices

Matthew Ondeck Ph.D. Materials Science and Biomaterials/Cancer BiologyEngineering/ Bioengineering

Seth Parker Ph.D. Bioengineering Cancer Metabolism

Gabriel Pratt Ph.D. Bioinformatics Genomics, RNA Biology andNeurodegeneration

Dustin Richmond Ph.D. Computer Engineering Hardware and System Design

Kevin Ross Ph.D. Biomedical Sciences Genetics

Benjamin Rubin Ph.D. Molecular Biology Genetics and Genomics

Suchol Savagatrup Ph.D. Chemical Engineering Conjugated Polymer Mechanics

Michael Tait Ph.D. Mathematics Extremal Combinatorics

Calandra Tomaszewicz Ph.D. Biology Endangered Species Ecology & Conservation

Stephanie Weng Ph.D. Biomedical Sciences Cancer Biology

Matthew Wingert Ph.D. Mechanical Engineering Nanomaterials Energy Transport

Christine Wittich Ph.D. Structural Engineering Earthquake Engineering

Page 6: ARCS® Foundation, Inc., San Diego Chapter

GRANT ALLENUniversity of California, San DiegoPhysics Department

Degrees:M.S. in Physics, University of California,San Diego

B.S. in Engineering Physics, Colorado School of Mines

Scholar Sponsor:Farrell Family Foundation

About the Scholar:Under the right conditions, disturbing a physical system canaffect a completely separate physical system, even if vastdistances separate the two. This affection is attributed to “quantum correlations” or “entanglement” and works via aseparate mechanism from the classical “cause and effect”notion of a force. Quantum correlations are said to be strongerthan classical types; however, in contrast, they cannot beshared freely. Grant’s research seeks to understand thefundamental limit in which multiple systems can shareentanglement. Furthermore, he is interested in findingnecessary or sufficient couplings that systems need in order toachieve these limiting entanglements. Grant’s most recentoutside interests are: spinning poi, juggling, and hunting forwild gourmet mushrooms in lush forests.

Benefits to Society:Quantum theory has the potential to add a novel layer ofcomplexity to current technology. Quantum devices, however,very often find it necessary to take advantage of quantumcorrelations - one famous example being a teleportation device,another being a quantum computer. By categorizing systemsaccording to the correlations they can generate, Grant’sresearch hopes to reveal the appropriate substrate with whichto build quantum devices for specialized protocols andalgorithms.

Awards and Honors:Summa Cum Laude Graduate, CSM

President’s Scholarship, CSM

Publications and Posters:Allen, G. W.; Meyer, D. A. Polynomial Monogamy Relations. 2015,arXiv:1502.04807 arXiv.org e-Print archive. http://arxiv.org/abs/1502.04807

Coffey, M. W.; Allen, G. Eigenvalue degeneracy relations for a fullyconnected isotropic spin network. J. Phys. A: Math. Theor. 2011, 44,395303.

LISA ALVAREZUniversity of San DiegoHahn School of Nursing and Health Science

Degrees:MSN/FNP, University of San Diego

ADN in Nursing, College of theAlbemarle, Elizabeth City NC

BA in Psychology, University of North Carolina, Chapel Hill NC

Scholar Sponsor:Beyster Family Foundation Fund IV

About the Scholar:Lisa wishes to improve collaboration between outpatient andinpatient care providers for heart failure populations. Currentlythere is a disconnect leading to incomplete dischargeinstructions and follow up for these patients. Lisa plans to leadnew practice changes to bridge the gap of resources frominpatient to outpatient and increase access care. She wants todevelop a heart failure pathway, with evidenced-basedpractices, and implement standard guidelines for nurseeducation and discharge instructions. Education and continuityof care will empower patients to take control of thisprogressive disease and therefore decrease 30-day readmissionrates. Lisa’s outside interests include hiking, yoga, running, andher two Italian greyhounds.

Benefits to Society:Having a cohesive flow to care will provide the communitythe best options and services for heart failure management.Heart failure is a progressive disease that affects 230 millionpeople, 2% of the population. Furthering science in heartfailure will greatly improve morbidity and mortality across allpatient populations. Lisa’s professional responsibility will beto use the resources that she will learn to change healthcareand disseminate research processes to combine them withcurrent practice.

Awards and Honors:Cardiac Surgery Clinical Excellence Team Quality Award: SharpHealthcare 2014

Sharp Guardian Angel Recipient 2015

4

Page 7: ARCS® Foundation, Inc., San Diego Chapter

LAURA ANDERSENUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Materials Science & Engineering,University of California, San Diego

B.S. in Materials Science & Engineering, University of Washington, Seattle

Scholar Sponsor:The Donald C. and Elizabeth M. Dickinson Foundation

About the Scholar:Laura is studying the fracture and wear properties of bulkmetallic glasses. Bulk metallic glasses are a special class ofmetallic materials created by rapid solidification, which causesthem to form glass-like structures. This unique atomic structureleads to ideal mechanical properties for excellent wearresistance. However, in order to exploit these materials, weneed to better understand their fracture mechanics. Laurahopes to define critical relationships between the atomicstructure, processing conditions and fracture properties ofthese ambiguous materials. Laura enjoys hiking, running, yoga,cooking, and beer brewing.

Benefits to Society:Improving the plasticity of bulk metallic glasses is currently oneof the hottest topics in the field of materials science because ofthe great scientific and technological importance of thesematerials. This work has had some success; however, it has notbeen followed up by widespread technological use. Lauraintends to design a bulk metallic glass by maximizing itsinherent properties such as hardness and wear-resistance,while retaining a minimum plasticity and toughness. Potentialapplications for such wear-resistant materials range fromgearbox materials to biomedical implants. This project will notonly enable the commercialization of bulk metallic glasses, butwill also provide insight as to how the structure and processingtranslate to the fracture toughness and wear properties.

Awards and Honors:Teaching Assistant Appreciation Award, UCSD Office forStudents with Disabilities

Abe Hurlich Scholarship, ASM San Diego Chapter

CAL-RA and Materials Science Fellowships, UCSD JacobsSchool of Engineering

RISE-Pro Scholarship, German Academic Exchange Service

The Boeing Company Academic Grant

Publications and Posters:Kolodziejska, J.; Roberts, S.N.; Andersen, L.M.; Hofmann, D.C.Exceptional wear resistance of Cu-based metallic glass. (In preparation).

Andersen, L.M.; Kolodziejska, J.; Hofmann, D.C.; Vecchio, K.S.Investigating the fracture mechanics of wear-resistant bulkmetallic glasses. Jacobs School 33rd Annual Research Expo, LaJolla, CA; April 17, 2014.

Andersen, L.M.; Hofmann, D.C.; Vecchio, K.S. Fracture and wearbehavior of amorphous metals for use as gearbox materials.Jacobs School 32nd Annual Research Expo, La Jolla, CA; April18, 2013.

VINCENT BERARDISan Diego State University/ClaremontGraduate University

Degrees:M.S. in Applied Mathematics, San DiegoState University

B.S. in Mathematics, Saint Peters Univ.

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:The overarching goal of Vincent’s research is to harness the powerof mobile technology to improve the way health-promotinginterventions are performed. Specifically, his research projectattempts to reduce secondhand smoke concentrations inhouseholds by placing monitors in the home that measure theconcentration of indoor air particle concentrations. The monitorsare fit with lights and sounds that activate once particle levelsexceed a threshold. He is attempting to identify patterns in thedata that will allow for more effective behavioral interventionsaimed at reducing indoor particle concentrations. Vincent’s outsideinterests include running, harmonica, and following the New YorkYankees.

Benefits to Society:The benefits of reducing secondhand smoke, particularly amongchildren (who live in every household within our study) are wellknown and incredibly important. In addition, the constant, real-time interaction participants have with the monitors is expected tobe much more effective than the intermittent interaction in atypical health intervention (e.g., meeting with a smoking cessationcounselor). His project focuses on increasing the specificity withwhich behaviors are identified. Doing so allows well-knownprinciples of behavior (e.g., reinforcement) to be employed withsignificantly more rigor with the intended effect of enhancingpublic health interventions.

Awards and Honors:Internal Advisory Committee Stipend (SDSU/UCSD San Diego CancerCenter Comprehensive Partnership, 2013-2014)

ESET Award for Achievement (SDSU CSRC ACCESS For Industry, 2014)

Academic Excellence in Mathematics, Graduate Student (San DiegoState University, 2013)

Kruze Award for Excellence in Mathematics, (Saint Peters College, May 2003)

Publications and Posters:Berardi, V.; Lydon, J.; Kevrekidis, P. G.; Daraio, C.; Carretero-González , R. Directed Ratchet Transport in Granular Crystals.Physical Review E. 2013, 88(5).

Bellettiere, J.; Hughes, S. C.; Liles, S.; Boman-Davis, M.;Klepeis, N. E.; Blumberg, E.; Mills, J.; Berardi, V.; Obayashi, S.;Allen, T. T.; Hovell, M. F. Developing and Selecting AuditoryWarnings for a Real-Time Behavioral Intervention. AmericanJournal of Public Health Research. 2014, 2(6), 232-238.

Berardi, V.; Carretero-González; Hovell, M. F.; Palacios, R. A NewModel for Behavioral Interventions. Presented at Society forChaos Theory in Psychology and Life Sciences, 23rd AnnualConference, Portland, Oregon, July 26, 2013.

5

Page 8: ARCS® Foundation, Inc., San Diego Chapter

JESSICA BRUHNThe Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.A. in Biochemistry, Biophysics andMolecular Biology, Whitman College

Scholar Sponsors:Roche/ARCS Foundation Scholar Award

About the Scholar:Jessica’s research focuses on the molecular and structuralproperties governing viral life cycles. She initially studied theRNA replication machinery from Nipah virus, solving a high-resolution crystal structure of one of these proteins. Nipahvirus causes encephalitis in Southeast Asia with up to 90%fatality, and this work has contributed to the understandingnecessary for the rational drug design. Her current research isfocused on Ebola virus, which has infected almost 30,000people in the ongoing West African outbreak. She is trying tobetter understand how the viral matrix protein forms newvirions, controls replication and suppresses the immunesystem. Jessica is an avid backpacker, rock climber andsnowboarder.

Benefits to Society:There are no approved therapeutics or vaccines available totreat and protect people from infection with Nipah and Ebolaviruses. Both of these viruses cause high mortality rates inhumans (70-90%) and affect some of the poorest communitiesacross the globe. This work provides a better understanding ofhow these viruses infect humans and how we can design betterdrugs to combat them in infected individuals.

Awards and Honors:Roche ScholarNIH training grant T32Delia and Donald Baxter FellowshipDean’s Fellowship

Publications and Posters:Jessica F. Bruhn*, Matthew Clifton*, Terry Webb, Ruth Baydo,Kateri Atkins, Amy Raymond, Don Lorimer,Thomas Edwards,Peter Myler, Erica Ollmann Saphire. Crystal structure of theSudan ebolavirus VP40 dimer. Journal of Infectious Diseases.Under review.

Jessica F. Bruhn, Katherine Barnett, Jaclyn Bibby, Jens Thomas,Ronan Keegan, Daniel Rigden, Zachary Bornholdt, EricaOllmann Saphire. Crystal structure of the Nipah virusphosphoprotein tetramerization domain. J. Virology 2014.

Bruno Correia, Yih-En Andrew Ban, Margaret Holmes, HengyuXu, Katharine, Ellingson, Zane Kraft, Chris Carrico, Erica Boni,D. Noah Sather, Camille Zenobia, Katherine Burke, TylerBradley-Hewitt, Jessica F. Bruhn-Johannsen, Oleksandr,Kalyuzhniy, David Baker, Roland Strong, Leonidas Stamatatos,and William Schief. “Computational Design of Epitope-ScaffoldsAllows Induction of Antibodies Specific for a PoorlyImmunogenic HIV Vaccine Epitope.” Structure 2010.

Bruno Correia, Yih-En Andrew Ban, Della Friend, KatharineEllingson, Hengyu Xu, Erica Boni, Tyler Bradley-Hewitt, JessicaF. Bruhn-Johannsen, Leonidas Stamatatos, Roland Strong andWilliam Schief. “Computational Protein Design Using FlexibleBackbone Remodeling and Resurfacing: Case Studies inStructure-Based Antigen Design.” J. Mol. Biol. 2010.

PETER CALHOUNSan Diego State UniversityCollege of Sciences

Degrees:M.A. in Statistics, University of Florida,Gainesville, FL

B.A. in Mathematics, Macalester College, St. Paul, MN

Scholar Sponsor:ARCS Foundation

About the Scholar:Peter’s research is about random forests, a statistical methodfor predicting outcomes with many observations. They requirefew assumptions, handle a variety of data structures, and areeasy to interpret. He applied similar statistical techniques to alarge dentistry dataset to predict tooth loss. The results will bepublished and will help dentists make better prognosis andimprove patient care. In the current era of big data, randomforests are a useful technique to make predictions. Peter playschess and various other board games as well as enjoys sports.

Benefits to Society:This research is general in the sense that it can be applied toany field where predictions are needed. There are many typesof models, but Peter’s research focuses on a technique thatdoes not rely on many assumptions and typically yields moreaccurate predictions. His research has led to publishing acode to predict outcomes in the healthcare field and improvepatient care.

Publications and Posters:Wilson, D., Calhoun, P., Maahs, D., Chase, H.P., Messer, L.,Buckingham, B., Aye, T., Clinton P., Hramiak I., Kollman, C., Beck,R. (2015) Factors Associated with Nocturnal Hypoglycemia inAt-Risk Adolescents and Young Adults with Type 1 Diabetes.Diabetes Technology and Therapeutics, 17: 385-391

Chase, H.P., Doyle, F., Zisser, H., Renard, E., Nimri, R., Cobelli,C., Buckingham, B., Maahs, D., Anderson, S., Lum, J., Calhoun,P., Kollman, C., Beck, R. (2014) Multi-Center Closed-Loop/HybridMeal Bolus Insulin Delivery with Type 1 Diabetes. DiabetesTechnology and Therapeutics, 16: 623-632

Maahs, D., Calhoun, P., Buckingham, B., Chase, H.P., Hramiak, I.,Lum, J., Cameron, F., Bequette, B.W., Aye T., Paul T., Slover R.,Wadwa, R., Wilson, D.M., Kollman, C., Beck, R. (2014) ARandomized Trial of a Home System to Reduce NocturnalHypoglycemia in Type 1 Diabetes. Diabetes Care, 37(7): 1885-1891. doi.10.2337/dc13-2159

Hovorka, R., Elleri, D., Thabit, H., Allen, J., Leelarathna, L., El-Khairi, R., Kumareswaran, K., Caldwell, K., Calhoun, P., Kollman,C., Murphy, H., Acerini C., Wilinska, M., Nodale, M., Dunger, D.(2014) Overnight Closed Loop Insulin Delivery in Young Peoplewith Type 1 Diabetes: A Free-Living, Randomised Clinical Trial.Diabetes Care, 37(5): 1204-1211. doi.10.2337/dc13-2644

6

Page 9: ARCS® Foundation, Inc., San Diego Chapter

7

GEORGE CAMPBELLThe Scripps Research InstituteThe Scripps Research Institute GraduateProgram

Degrees:B.S. in Biology, B.S. in Chemistry,University of Tennessee at Chattanooga

Scholar Sponsor:Hervey Family Non-Endowment Fund

About the Scholar:George’s research seeks to understand how essential materialsare transported inside each individual brain cell. The transportof key materials inside brain cells is frequently impaired inneurodegenerative diseases, such as Alzheimer’s disease. Itremains unclear whether a failure in transport is a symptom ora cause of neurodegeneration. He studies the mechanisms thatcontrol transport, and how they are affected byneurodegenerative diseases. By understanding the interplaybetween intracellular transport and neurodegeneration, noveltreatments may be proposed and developed. Outside of thelab, George enjoys archery, Improv Comedy, and board games.

Benefits to Society:Further understanding of transport mechanisms in neuronsmay provide new knowledge with relevance to severalneurodegenerative diseases. The most common neuro-degenerative disease, Alzheimer’s disease, afflicts millions inthe U.S. alone, and this number is expected to grow rapidly inthe coming years.This rapid growth in Alzheimer’s patientsmeans that neurodegeneration research, such as understandingthe role of axonal transport in neurodegenerative disease, is apriority for public health, which could provide the foundationfor novel treatments for currently incurable diseases.

Awards and Honors:NIH Clinical and Translational Science Award Traineeship

Student Poster Award, Annual Meeting of the Association ofSoutheastern Biologists

Outstanding Research Award

S.G.A. Outstanding Senior in B.S. Biology: Molecular

Murray Raney Chemistry Scholarship

Publications and Posters:Neumann, S., Campbell, G. E., Szpankowski, L., Goldstein, L. S.B., Encalada, S. E. Characterizing the Composition of MolecularMotors on Moving Axonal Cargo Using "Cargo Mapping"Analysis. J. Vis. Exp. 2014, 92, e52029.

Campbell, G.E.; Encalada, S.E. Coordination of MolecularMotors in Axonal Transport; Graduate Student Retreat, TheScripps Research Institute, Lake Arrowhead, CA.; October 2014.

Campbell, G.E., Searching for Genetic Control: A Closer Look atMethylation Patterns and Microsatellites in Colon Cancer.Departmental Honors Thesis. The University of Tennessee atChattanooga, Chattanooga, TN, 2011.

Campbell, G.E.; Kovach, M.J. Searching for Genetic Control: ACloser Look at Methylation Patterns and Microsatellites inColon Cancer, 72nd Annual Meeting of the Association ofSoutheastern Biologists, Huntsville, AL; April 2011.

RUSSELL CHANUniversity of California, San DiegoDepartment of Chemistry andBiochemistry

Degrees:M.S. in Biochemistry, University ofCalifornia, San Diego

B.S. in Biology, University of California, Riverside

Scholar Sponsor:Timken-Sturgis FoundationAbout the Scholar:Russell’s research focuses primarily on the structural biology ofRNA splicing, which is a process that removes non-codingregions from genetic transcripts. In bacteria, splicing is catalyzedby an RNA enzyme, known as the group II intron, which iscapable of self-splicing. In eukaryotes, this reaction is catalyzedby a large RNA-protein complex known as spliceosome. UsingX-ray crystallography, he has determined the structure of twogroup II introns. Russell’s current objective is to captureintermediate states of the group II intron at different stages ofthe splicing pathway. This will provide insight into how thegroup II intron selects optimal splice sites and proceeds througheach splicing step with high fidelity. Russell is currentlyinterested in computer programming. He also enjoyssnowboarding, playing basketball and board games.

Benefits to Society:RNA splicing is responsible for the removal of non-codingsequences (introns) from genes and simultaneously joiningcoding sequences (exons) together. Alternative splicing eventsallow multiple combinations of exons to be included in the finalmessage, greatly expanding the number of proteins coded froma single genome. Above all else, splicing must proceed withcomplete accuracy in order to maintain the correct proteincoding sequence. Introns comprise ~25% of the human genome.Currently, it is believed that a large number of genetic diseasesare the result of defects in splicing. Obtaining three-dimensionalmodels of the spliceosome or group II intron at different steps ofsplicing could lead to a greater understanding of how splice sitesare selected and result in the development of therapeutics tocombat splicing-associated diseases.

Awards and Honors:Inamori Foundation Fellowship, 2015

Graduate Student Research Award, International Conference onthe Crystallization of Biological Macromolecules, 2012

NIH Cellular and Molecular Genetics Training Grant Recipient,UCSD, 2011-2014

Publications and Posters:Chan R.T. and Robart A.R.; Peters J.K.; Toor N. Structural dynamicsof the catalytic triplex during RNA splicing. 2015, In preparation.

Robart A.R.; Chan R.T.; Peters J.K.; Rajashankar K.R.; Toor N.Crystal structure of a eukaryotic group II intron lariat. Nature.2014, 7521, 193-197.

Chan R.T.; Robart A.R.; Rajashankar K.R.; Pyle A.M.; Toor N.Crystal structure of a group II intron in the pre-catalytic state.Nature Structural & Molecular Biology. 2012, 19, 555–557.

Page 10: ARCS® Foundation, Inc., San Diego Chapter

8

MICHELLE CHENUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Civil and EnvironmentalEngineering, University of California,Berkeley

B.S. in Structural Engineering, University of California, San Diego

Scholar Sponsor:The Beyster Family Foundation Fund IV About the Scholar:Michelle studies a technology called seismic isolation thatimproves the behavior of buildings during earthquakes andprotects them from damage. She has conducted a uniqueshake table experiment which tested a full scale 5 storybuilding fully outfitted with nonstructural equipment (furniture,staircase, facade, etc.) and analyzed the building’s seismicperformance with and without the seismic isolators. She hasalso performed testing of a seismic isolator to furtherunderstand its performance characteristics. The goal of herresearch is to protect buildings and building contents fromdamage in an earthquake event through the use of seismicisolation. In her free time, Michelle enjoys outside activitieswith her puppy.

Benefits to Society:Seismic isolation is an effective technology that can protectbuildings and building contents from damage duringearthquakes. It is vital for any community that hospitals andemergency facilities remain fully functional immediately afteran earthquake, and schools must protect students. Currentbuilding design practices are aimed to save lives but allowdamage in buildings, leading to costly repairs and downtime.Michelle’s research will help the use of seismic technologygrow in the U.S. by filling in important research gaps.

Awards and Honors:National Science Foundation Integrative Graduate Research andEducation Traineeship

Tau Beta Pi

Publications and Posters:Chen, M.; Restrepo, J.I.; Benzoni, G. Performance of a HighDamping Rubber Bearing to Multiaxial Excitation. Proceedings ofthe 14th World Conference on Seismic Isolation, Energy Dissi-pation and Active Vibration Control of Structures (14WCSI), 2015.

Chen, M.; Pantoli, E.; Wang, X.; Astroza, R.; Ebrahimian, H.;Hutchinson, T.; Conte, J.; Restrepo, J.; Marin, C.; Walsh, K.;Bachman, R.; Hoehler, M.; Englekirk, R.; Faghihi, M. Full-scalestructural and nonstructural building system performanceduring earthquakes: part I – specimen description, test protocoland structural response. Earthquake Spectra, 2015 (Accepted).

Chen, M.; Pantoli, E.; Wang, X.; Astroza, R.; Ebrahimian, H.;Mintz, S.; Hutchinson, T.; Conte, J.; Restrepo, J.; Meacham, B.;Kim, J.; Park, H. BNCS report #1: full-scale structural andnonstructural building system performance during earthquakesand post-earthquake fire - specimen design, construction andtest protocol. Structural Systems Research Project ReportSeries, SSRP 13/9. University of California San Diego, La Jolla,CA, 2013.

MONICA CHUUniversity of California, San DiegoDivision of Biological Sciences

Degrees:B.S. in Biology, Massachusetts Institute ofTechnology

Scholar Sponsor:ARCS Foundation Endowment FundAbout the Scholar:Monica’s research aims to understand how the activity ofneurons in the brain changes with experience. She is using acutting-edge technique called in vivo two-photon calciumimaging to record the activity of neuronal populations in themouse olfactory bulb, which is the first relay station ofolfactory information in the brain. This technique enables her tofollow the activity of hundreds of neurons over months inawake behaving animals, and allows her to better understandhow odor information in the brain is shaped by things likebehavioral state or learning. Outside of the lab, Monica enjoysswimming and crafting.

Benefits to Society:Monica’s research aims to better understand the changesoccurring in the brain during learning. Even after we reachadulthood, our brains can undergo changes whenever we learnsomething new. One particular type of change is calledperceptual learning, which occurs with sensory experience. Forexample, with experience, parents of twin children caneventually learn to distinguish between their children usingsubtle visual cues. Her research studies this process pertainingto the sense of smell in the mouse. Specifically, she wants tounderstand the changes that occur with perceptual learning inan early olfactory area of the brain called the olfactory bulb.

Awards and Honors:NIH Cellular and Molecular Genetics Training Grant Recipient

Publications and Posters:Kato, H.K.*; Chu, M.W.*; Isaacson, J.S.; Komiyama, T. Dynamicsensory representations in the olfactory bulb: modulation bywakefulness and experience. Neuron 2012, 76(5):962-75.

Kay, J.N.; Chu, M.W.; Sanes, JR. MEGF10 and MEGF11 mediatehomotypic interactions required for mosaic spacing of retinalneurons. Nature 2012, 483(7390):465-9.

Kay, J.N.; Voinescu, P.E.; Chu, M.W.; Sanes, J.R. Neurod6expression defines new retinal amacrine cell subtypes andregulates their fate. Nat Neurosci 2011, 14(8):965-72

Page 11: ARCS® Foundation, Inc., San Diego Chapter

9

RIGO CINTRON-COLONThe Scripps Research InstituteDoctoral Program in Chemical andBiological Sciences

Degrees:B.S. in General Natural Science,Universidad del Sagrado Corazon

Scholar Sponsor:ARCS FoundationAbout the Scholar:Core body temperature is an indispensable component fororganismal viability. Core body temperature remains constantwithin a narrow range of variation during normal physiology;however, changes to core body temperature could beassociated to pathology, affecting organismal health. Rigo’sresearch project aims to investigate the molecular and cellularmechanisms that mediate thermoregulation, specifically inbrain regions that have been reported to function as the body’sthermostat. Moreover, he aims to elucidate the cellular andbiochemical mechanism involved in the integration oftemperature and nutrient homeostasis, as they are the mainregulators of health, aging and metabolism. In his spare time,Rigo enjoys playing beach volleyball, hiking and running.Having a strong interest in helping others, he tries to beinvolved in community outreach activities.

Benefits to Society:Understanding the molecular mechanisms modulating theintegration of nutrient and temperature homeostasis isphysiologically relevant to energy homeostasis, which isresponsible for sustaining life of homeothermic organisms.Reducing calorie intake prolongs lifespan and subsequently,core body temperature decreases upon calorie intakereduction. Thus, the molecules regulating core bodytemperature to calorie intake reduction are potential targets forage-related diseases. Furthermore, the findings of Rigo’sresearch can have an impact in pointing out novel routes totreat metabolic disorders like obesity, and other syndromessuch as cachexia.

Awards and Honors:Honorable Mention in the 2015 FORD (National Academies) pre-doctoral fellowship program solicitation.

Academic Excellence Award to the student with the highestGPA of 2014 graduating class from Universidad del SagradoCorazon.

2014 Biomedical Sciences Preview Weekend Scholar atUniversity of Minnesota, Twin Cities for prospective highlyqualified candidates applying to graduate school.

2013 Portico Medal award of Universidad del Sagrado Corazon.This faculty-nominated award is given to students that showleadership and academic excellence during their undergraduatestudies.

NIH-Blueprint-ENDURE neuroscience research training fellow atUniversity of Puerto Rico, Rio Piedras Campus.

Publications and Posters:Cintron-Colon, R.G.; Vega, I.E. Molecular mechanism ofPaclitaxel-induced degradation of SCG10: a potentialneuropathy biomarker. Presented at Experimental Biology, SanDiego, CA, April 26-30, 2014.

Cintron-Colon, R.G.; Vega, I.E. Molecular mechanism ofPaclitaxel-induced degradation of SCG10: a potentialneuropathy biomarker. Presented at Society for Neuroscience,San Diego, CA, November 9-13, 2013.

DANIEL CUEVASSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Computer Science, San Diego State University

Scholar Sponsor:Virginia Lynch Grady Endowment

About the Scholar:Daniel’s research consists of building mathematical modelsrepresenting the metabolic network of bacterial cells. Heobtains the information to build these models by firstsequencing the genome of the bacteria. Then, usingbioinformatics, he identifies the presence of genes encodingproteins and enzymes that take part in the cell’s metabolism.Using these models, he is able to simulate how a particularbacterial cell will behave in various environmental conditions;for example, conditions containing different food sources. Inaddition, he can manipulate and test the model in ways thatmimic how scientists alter bacterial cells during real wet-labexperiments. Daniel’s other interests include exercising,running, playing sports, watching movies, reading scienceliterature and tech blogs, listening to a variety of music, as wellas spending time with his wife and family.

Benefits to Society:Models allow scientists to rapidly simulate experiments andfurther understand aspects of their modeled system. With thesemetabolic models, experiments that are usually costly in timeand money can be simulated within minutes. Metabolic modelsare used widely by research facilities involved in exploitingbacteria, such as in biofuel development and the pharma-ceutical industry. These establishments attempt to alter thebacterial cell to produce useful metabolic compounds that canultimately benefit human life in terms of energy and health.

Awards and Honors:2014 GEN TEN Award from Genetic Engineering andBiotechnology News Publisher (June 2014)Graduate S-STEM NSF Scholarship for the past two years(January 2014)11th Annual Rocky Mountain Bioinformatics Conference posterwinner (December 2013)Statistical Biomedical Informatics Scholarship (August 2012)NIH New Interdisciplinary Workforce Fellow (July 2009)

Publications and Posters:Sanchez, S. E.; Cuevas, D. A.; Rostron, J. E.; Liang, T. Y.; Pivaroff, C. G.;Haynes, M. R.; Nulton, J.; Felts, B.; Bailey, B. A.; Salamon, P.; Edwards, R.A.; Burgin, A. B.; Segall, A. M.; Rohwer, F. Phage Phenomics:Physiological Approaches to Characterize Novel Viral Proteins. Journal ofVisualized Experiments: JoVE 2015, No. 100, e52854.

Cuevas, D. A.; Garza, D.; Sanchez, S. E.; Rostron, J.; Henry, C. S.;Vonstein, V.; Overbeek, R. A.; Segall, A.; Rohwer, F.; Dinsdale, E. A.;Edwards, R. A. F1000Research 2014.

Lim, Y. W.; Cuevas, D. A.; Silva, G. G. Z.; Aguinaldo, K.; Dinsdale, E. A.;Haas, A. F.; Hatay, M.; Sanchez, S. E.; Wegley-Kelly, L.; Dutilh, B. E.;Harkins, T. T.; Lee, C. C.; Tom, W.; Sandin, S. A.; Smith, J. E.; Zgliczynski,B.; Vermeij, M. J. A.; Rohwer, F.; Edwards, R. A. Sequencing at Sea:Challenges and Experiences in Ion Torrent PGM Sequencing during the2013 Southern Line Islands Research Expedition. PeerJ 2014, 2, e520.

Dutilh, B. E.; Thompson, C. C.; Vicente, A. C.; Marin, M. A.; Lee, C.; Silva,G. G.; Schmieder, R.; Andrade, B. G.; Chimetto, L.; Cuevas, D.; Garza, D.R.; Okeke, I. N.; Aboderin, A. O.; Spangler, J.; Ross, T.; Dinsdale, E. A.;Thompson, F. L.; Harkins, T.T.; Edwards, R. A. Comparative Genomics of274 Vibrio Cholerae Genomes Reveals Mobile Functions StructuringThree Niche Dimensions. BMC Genomics 2014, 15 (1), 654.

Page 12: ARCS® Foundation, Inc., San Diego Chapter

10

DAVID CURRANSan Diego State UniversityCollege of Engineering

Degrees:B.A. in Economics Management, OhioWesleyan University

Scholar Sponsor:ARCS Foundation

About the Scholar:David is researching novel techniques for storing thermalenergy (heat) in a concentrated solar power application.Concentrated solar power uses a field of mirrors to focus thesun’s irradiation to a single collector, which can harness thatenergy to generate electricity equivalent to a fossil-fuel basedpower plant. Thermal storage allows us to be able to harnessthe power collected from the sun, even after the sun has gonedown. His research involves using phase change metal alloysas a storage medium, capable of storing high temperatures forhours after the sun goes down. David is a mountaineer andbaseball player.

Benefits to Society:The Department of Energy’s SunShot Initiative called for asignificant decrease in levelized cost of electricity, a measure ofinstallation and operation costs, to promote widespreadadoption of concentrated solar power plants. Two ways toreach those goals are raising operating temperatures andimplementing thermal storage. David’s research wouldaccomplish both goals. If the technology proves valid,concentrated solar power can become a valid alternative forfossil fueled power plants while simultaneously using lesswater than traditional plants.

Awards and Honors:Dean’s Award for Research- College of Engineering, 2015, SanDiego State University Student Research Symposium

Best Graduate Student Research – 2015, American Society ofMechanical Engineers, Solar Energy Division

Jon and Barbara Yellott Award for Best Graduate Research –2015, American Solar Energy Society

Publications and Posters:Curran, D. Miller, F. Hunt, A. Carrington, R. “An Evaluation ofContainment Materials for High Temperature Metal ThermalStorage Sytems.” Paper presented at the Proceedings ofASME Power and Energy Conference, San Diego, CA, June 28-July 2, 2015.

CHRISTOPHER DEBOEVERUniversity of California, San DiegoBioinformatics and Systems Biology

Degrees:B.S. in Mathematical Biology, Harvey MuddCollege

Scholar Sponsor:The Heller Foundation of San Diego

About the Scholar:Chris uses genomics to study human disease with a focus oncancer and stem cell biology. He has studied the role ofmutations in the splicing factor SF3B1 in chronic lymphocyticleukemia (CLL) and investigated how the genomic landscape ofCLL changes as the disease progresses. He is also usinggenomic data from a large cohort of induced pluripotent stemcells and differentiated cardiomyocytes to study the role ofgenetics in human cardiac phenotypes and disease. Besideswork, he likes exploring the outdoors, playing guitar, reading,and music.

Benefits to Society:The sequencing revolution in biology has provided us with awell-documented flood of genomics data. Processing,interpreting, and utilizing these data present unique challengesbut also offer the ability to study biology at an unprecedentedlevel of breadth and depth. Chris’s work is aimed at utilizinggenomics data to learn about human biology and disease andtranslate this knowledge to the clinic to both improve diagnosisand treatment and lower healthcare costs. His work buildstoward a future where genomic analysis is a cornerstone ofmedical care.

Awards and Honors:UC San Diego Research Integrity Student Award

St. Jude National Graduate Student Symposium

Best Poster, UCSD Bioinformatics and Systems BiologyResearch Expo (2014)

Best Talk, UCSD Bioinformatics and Systems Biology ResearchExpo (2013)

Best Poster, UCSD Genetics Training Program Annual Retreat (2013)

Publications and Posters:DeBoever C; Ghia EM; Shepard PJ; Rassenti L; Jepsen K;Jamieson CHM; Carson D; Kipps TJ; Frazer KA. Pan-canceranalysis shows SF3B1 mutations cause widespread cryptic 3’splice site selection downstream of the branch point. PLoSComputational Biology. 2015. in press.

Cheng CP; DeBoever C; Frazer KA; Liu YC; Tseng VS. MiningABs:mining associated biomarkers across multi-connected geneexpression datasets. BMC Bioinformatics. 2014, 15:173.Doi:10.1186/1471-2105-15-173

DeBoever C; Reid EG; Smith EN; Wang X; Dumaop W;Harismendy O; Carson D; Richman D; Masliah E; Frazer KA.Whole transcriptome sequencing enables discovery andanalysis of viruses in archived primary central nervous systemlymphomas. PLOS One. 2013; 8(9): e73956. Doi:10.1371/journal.pone.0073956

Barrett CL; DeBoever C; Jepsen K; Saenz CC; Carson DA; FrazerKA. Systematic transcriptome analysis revals tumor-specificisoforms for ovarian cancer diagnosis and therapy. PNAS. 2015;112(23): E0350-E3057; doi: 10.1073/pnas.1508057112.

Page 13: ARCS® Foundation, Inc., San Diego Chapter

11

EDWARD DECHAUMPHAIUniversity of California, San DiegoJacobs School of Engineering

Degrees:B.S. in Mechanical Engineering, University of Maryland at College Park

Scholar Sponsor:Wally Schirra Memorial Fund

About the Scholar:Edward has two research projects. One is to develop a verysensitive heat sensor for biomedical applications. He isdeveloping a microchip platform that monitors the heat(metabolic rate) of cells and observes how it changes withexternal stimuli such as drugs. This microchip can be used indrug discovery process, bacteria detection, and as a tool inbiology research. The second project is to understand how heatbehaves differently at a very small scale since overheating isthe main problem in tiny electronics such as microchips. Hisresearch also looks at how to efficiently cool these smallelectronic components. He loves to play soccer andbadminton.

Benefits to Society:Heat and temperature play a very important role in our dailylives. For instance, as electronic devices get smaller,overheating is the major bottleneck in devices development.Therefore, having a clearer understanding in micro/nano-scalethermal transport is crucial in future electronics. Furthermore,sensing heat and temperature of biological samples canprovide progress to biomedical sciences. The developedmicrochip calorimeter can be exploited to accelerate drugdiscovery processes, provide faster bacteria detection, andused as a new tool to understand biology.

Awards and Honors:CalIT2 fellowship

California Research Assistantship Fellowship

The SUEZ Energy Generation NA Scholarship

H. Russell Knust Memorial Scholarship

A. James Clark School of Engineering Scholarship

Publications and Posters:Dechaumphai, E.; Chen, R. Sub-picowatt resolution calorimetrywith niobium nitride thin-film thermometer. Review of ScientificInstruments 2014, 85, 094903.

Dechaumphai, E.; Lu, D.; Kan, J. J.; Moon, J.; Fullerton, E. E.;Liu, Z.; Chen, R. Ultralow thermal conductivity of multilayerswith highly dissimilar Debye temperatures. Nano Letters 2014,14 (5), 2448-2455.

Dechaumphai, E.; Barton, J. L.; Tesmer, J. R.; Moon, J.; Wang, Y.Q.; Tynan, G. R.; Doerner, R. P.; Chen, R. Near-surface thermalcharacterization of plasma facing components using the 3-omega method. J. Nucl. Mater. 2014, 455, 56-60.

Dechaumphai, E.; Chen, R. Thermal transport in phononiccrystals: the role of zone folding effect. J. Appl. Phys. 2012, 111,073508.

MIKE DENNY, JR.University of California, San DiegoDivision of Physical Sciences

Degrees:M.S. in Chemistry, University of California,San Diego

B.S. in Chemistry, Villanova University

B.S. in Biochemistry, Villanova University

Scholar Sponsor:ARCS Foundation Endowment Fund

About the Scholar:Metal-organic frameworks (MOFs) are a class of crystallineporous materials that hold great potential for a variety of real-world applications ranging from separation to catalysis. Thereason for MOFs’ potential is that their pore dimensions andchemical environment can be readily tailored while maintaininga rigid, crystalline framework. Despite their promise, industrialutilization of MOFs remains low due to difficulty in handlingand processing raw MOF powders. Utilizing a polymeric binder,Mike has fabricated mixed matrix membranes from a variety ofMOFs to allow for easy handling and is investigating thesemembranes for a variety of liquid and gas purificationapplications. He enjoys surfing, sailing, hiking, camping, andtravel in his spare time.

Benefits to Society:Mike is investigating the use of membranes for the separationand capture of toxic compounds from air and water. Oneavenue of this work is focused on removal of pollutants fromwater. He can tailor materials selectively to removecontaminants like heavy metals. Another aim of his work is touse membranes for removal of toxic chemicals from air forintegration into protective gear (gas masks, etc.) for ourmilitary and first responders.

Awards and Honors:American Chemical Society, Division of Inorganic ChemistryTravel Award – 250th National Meeting, Aug. 2015

Chancellor’s Interdisciplinary “Collaboratories” Award,University of California, San Diego

Harold Urey Fellowship (2012-2013), Dept. of Chemistry andBiochemistry, University of California, San Diego

Publications and Posters:Denny, Jr., M. S.; Cohen, S. M. Books of Abstracts, 250th ACSNational Meeting, Boston, MA, August 16-20, 2015; AmericanChemical Society: Washington, DC, 2015; INOR-512.

Denny, Jr., M. S.; Cohen, S. M. In Situ Modification of Metal-Organic Frameworks in Mixed- Matrix Membranes. Angew.Chem. Int. Ed., 2015, 54, 9029-9032.

Patterson, J. P.; Abellan, P.; Denny, Jr., M. S.; Park, C.; Browning,N. D.; Cohen, S. M.; Evans, J. E.; Gianneschi, N. C. Observingthe Growth of Metal–Organic Frameworks by in Situ Liquid CellTransmission Electron Microscopy. J. Am. Chem. Soc., 2015,137, 7322–7328.

Cao, Y.; Denny, Jr., M. S.; Caspar, J. V.; Farneth, W. E.; Guo, Q.;Ionkin, A. S.; Johnson, L. K.; Lu, M.; Malajovich, I.; Radu, D.;Rosenfeld, H. D.; Roy Choudhury, K.; Wu, W. High-EfficiencySolution-Processed Cu2ZSn(S,Se)4 Thin-Film Solar CellsPrepared from Binary and Ternary Nanoparticles. J. Am. Chem.Soc., 2012, 134, 15644–15647.

Page 14: ARCS® Foundation, Inc., San Diego Chapter

DINNAH DIDULOUniversity of San DiegoHahn School of Nursing and Health Science

Degrees:M.S. in Nursing Education, University ofCalifornia, San Francisco

B.S. in Nursing, San Diego State University

A.S. Degree in Nursing, Fresno City College

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:Diabetes is a progressive and chronic disease that can affectanyone who may be at risk. Early identification of at-risk peopleis crucial in order to provide a plan to manage the effects ofthis chronic disease. The objectives of Dinnah’s research are toidentify barriers that prevent early identification of diabetes inthe Filipino population (believed to be a high risk population)and to propose solutions to overcome these barriers. Hiking,biking, and cooking help Dinnah decrease her stress level, soshe can recharge and stay focused on her studies.

Benefits to Society:Dinnah is creating protocols to identify Filipinos who are athigh risk for diabetes. These protocols can serve as a guidelinefor health care providers to decrease the incidence ofcardiovascular disease, blindness, renal failure and limbamputation caused by delayed diagnosis and cultural barriers.The benefit of her research is to decrease the overall cost andburden of care by proposing early identification and treatment.This research can serve as a model for other Asian populationsfrom the Western Pacific Region who are at high risk fordiabetes as well.

Awards and Honors:Nurse Educator of the Year 2007, Philippine Nurses Associationof San Diego

Sigma Theta Tau, Alpha Eta Chapter: UCSF

Sigma Theta Tau, Zeta Mu: USD

Dean’s List, Fresno City College

Whittier Institute of Diabetes, Scholarship recipient; DiabetesEducator

IGOR FEDEROVUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. In Electrical Engineering, Universityof Illinois at Urbana-Champaign (2014)

B.S. In Electrical Engineering, University of Illinois at Urbana-Champaign (2012)

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:Igor’s main interests are using signal processing and machine learningtechniques to help people with audio-visual tasks. He has beenworking on an active speech “denoising” headset which will enablepeople working in harsh audio environments to communicate withone another. In addition, he has been working on a virtual realityapplication to allow users to interact with objects in the virtual world.In the coming years, he hopes to develop systems which merge audioand video content to enhance communication between people and toenable hearing in hearing impaired users. His hobbies include playingtennis, volleyball, and hiking.

Benefits to Society:Igor’s research aims to help people with audio and visual tasks. Hiswork in speech enhancement will not only allow people tocommunicate in harsh noise environments, but it will also improvespeech intelligibility in hearing aids for hearing impaired users.Merging audio and video systems will mimic the way that peopleactually interact with the world and allow for more robust systemsthat can “denoise,” enhance, and/or transcribe speech.

Awards and Honors:ECE Departmental Fellowship, University of California, San-Diego (2014)Jules D. Falzer Scholarship, University of Illinois at Urbana-Champaign (2012)Grainger Research and Leadership Award, University of Illinoisat Urbana-Champaign (2009-2010)

Publications and Posters:Fedorov, I. Kinect depth video compression for action recognition.Master's thesis, University of Illinoit at Urbana-Champaign, Urbana,IL, 2014.

Khosrowpour, A; Fedorov, I; Holynski, A; Niebles, J.C.; Golparvar-Fard, M. Automated Worker Activity Analysis in Indoor Environmentsfor Direct-Work Rate Improvement from long sequences of RGB-DImages. Construction Research Congress. 2014.

Shenoy, P.S. ; Fedorov, I; Neyens, T.; Krein, P.T. Power delivery forseries connected voltage domains in digital circuits. InternationalConference on Energy Aware Computing (ICEAC). 2011, 1-6, IEEE.

12

Page 15: ARCS® Foundation, Inc., San Diego Chapter

13

DANIELLE GROTJAHNThe Scripps Research InstituteDepartment of Molecular andExperimental Medicine; Department ofComputational and Structural Biology

Degrees:B.S in Biology with Honors in Research,B.S in Spanish, University of Wisconsin-Madison

Scholar Sponsor:Reuben H. Fleet Foundation

About the Scholar:Danielle uses a combination of techniques to visualizemicroscopic motor proteins that carry out the importantfunction of moving nutrients and signaling molecules tospecific destinations within a cell. This transport process isparticularly important in neurons, where the efficient transportof these components along elongated processes is essential forneuronal health and function. By studying both the livetransport and structure of motor proteins and their associatedcargoes using high-resolution microscopy, she hopes to gain abetter understanding of the mechanisms that regulate thesetransport complexes in their native environments. Danielleenjoys outdoor activities such as hiking and camping as well asyoga. She also chairs the Network for Women in Science(NWiS) at The Scripps Research Institute.

Benefits to Society:Increasing evidence suggests that impairments to the intracellulartransport machinery contribute to the pathologies associated withmany neurodegenerative diseases, including Amyotrophic LateralSclerosis (ALS) and Alzheimer’s disease. Although able to relievesymptoms of disease, no current therapies can prevent theprogressive death of neurons in patients suffering from neuro-degenerative disease. Therefore, these studies of motor proteinregulation will build a vital foundation for the development ofpowerful therapeutics that could eventually liberate society fromthese devastating diseases.

Awards and Honors:National Science Foundation (NSF) Graduate ResearchFellowship

The Kellog School for Science and Technology Dean’sFellowship

The Cargill Benevenga Research Fund Scholarship

The College of Agricultural and Life Sciences UndergraduateScholarship

Publications and Posters:Ge, X., Grotjahn, D., Welch, E., Holguin, C., Lyman-Gingerich, J.,Dimitrova, E., Abrams, E., Marlow, F., Yabe, T., Mullins, M.,Pelegri, F. Hecate/Grip2a acts to reorganize the cytoskeleton inthe symmetry-breaking event of embryonic axis induction.PLoS Genetics. 2014; 10(6): e1004422doi:10.1371/journal.pgen.1004422.

Grotjahn, D., Lander, G.C., Encalada S.E. UltrastructuralCharacterization of Motor Protein Conformation and Regulationin Neurons; Graduate Student Retreat, The Scripps ResearchInstitute, Lake Arrowhead, CA.; October 2014.

DANIELLE HAGSTROMUniversity of California, San DiegoDivision of Biological Sciences

Degrees:B.S. in Molecular Biology, University ofCalifornia, San Diego

Scholar Sponsors:ARCS Foundation, Susan Hoekenga & Edward Gergosian

About the Scholar:Danielle is analyzing how low doses of common pesticides damagethe developing brain. The most commonly used pesticides impair animportant regulator of neurons controlling movement. While lowdoses of these abundant pesticides do not harm adults, they aresuggested to specifically damage the developing infant brain. Danielleis using flatworms which have remarkable regenerative capabilitiessuch that after amputation they can regrow a functional brain within 1-2 weeks. Using this incredible model system, Danielle is studyingexactly how these chemicals target the developing brain and whateffect that has on behavior. She is very passionate about teaching andmentoring students of all ages to get them excited about science.Outside of science, she enjoys puzzles and playing video games.

Benefits to Society:The growing prevalence of childhood neurological diseases has beensuggested to be due to the abundance of environmental toxins,particularly pesticides. Danielle’s work examines how low doses ofthese chemicals affect the developing brain. This work will help guidethe development of more appropriate exposure guidelines andpreventative therapies. Particularly, flatworms provide a quicker,cheaper and less morally questionable alternative to classicalmammalian models allowing for rapid preliminary testing to guidemore targeted future studies in mammals.

Awards and Honors:NIH Cellular and Molecular Genetics Training Grant Recipient(2014)

Phi Beta Kappa (2012)

UCSD Biological Sciences Eureka! Scholarship recipient (2012)

UC Regents Scholar (2008-2012)

Publications and Posters:Hagstrom, D.; Cochet-Escartin, O.; Zhang, S.; Khuu, C.; Collins, E-M. S.Freshwater Planarians as an Alternative Animal Model for Neuro-toxicology. Toxicol. Sci. 2015, 147 (1), 270-285.

Hagstrom, D.; Ma, C.; Guha-Polley, S.; Subramani, S. The uniquedegradation pathway of the PTS2 receptor, Pex7, is dependent on thePTS receptor/co-receptor, Pex5 and Pex20. Mol. Biol. Cell. 2014, 25(17),2634-2643.

Hagstrom, D.; Ma, C. Biochemically characterizing the subcellularlocalization of peroxisomal proteins by fractionation, proteaseprotection, and carbonate extraction. In Yeast Protocols; Methods inMolecular Biology Series 1163; Springer: New York, 2014; pp 175-181

Ma, C.; Hagstrom, D.; Guha-Polley, S.; Subramani, S. Redox-regulatedcargo binding and release by the peroxisomal targeting signal, Pex5.J. Biol. Chem. 2013, 288(38), 27220-31.

Page 16: ARCS® Foundation, Inc., San Diego Chapter

14

BRYAN HANCOCKSan Diego State UniversitySan Diego State University and University of California San Diego JointDoctoral Program in Cellular andMolecular BIology

Degrees:B.S. in Biochemistry and Cell Biology, University of California, San Diego

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:Bryan’s research is focused on how the human bacterialpathogen, Group B Streptococcus (GBS) is able to cross theblood-brain barrier and induce inflammation leading tomeningitis. Specifically he uses zebrafish to model GBSinfections and look at how the disease is able to progress inreal time. He is using this model as well as immortalizedvascular brain cells to identify specific host signaling factorsthat are activated in response to GBS infection. The goal of thisresearch is to understand what protein and signaling pathwaysare activated in human vascular brain cells that enable GBS tocross the blood-brain barrier and cause disease. Bryan enjoysspending time with his kids as well as comic books, localmusic, and craft cocktails.

Benefits to Society:By identifying specific host proteins that are activated in responseto GBS infection, Bryan hopes to describe the pathway by whichGBS is able to gain entry into, and thus infect human cells. Thisresearch will lead to a better understanding of GBS pathogenicitythat will in effect add to our knowledge of this human pathogen.The overarching goal of this work is to identify steps in theinfection cycle that could potentially be inhibited to reduce the riskof disease.

Awards and Honors:29th Annual California State University Student ResearchCompetition, Biological and Agricultural Sciences Award:selected #1 overall in biology. San Diego State University Student Research SymposiumPresident’s Award: One of the 10 recipients who went on topresent at the 29th Annual CSU Research Competition. Sharp/Reese-Steely, SDSU Heart Institute Fellowship, an annual$8,333 award American Society for Microbiology Travel Grant, enabling travel toASM General Meeting 2015 in New Orleans to present research. Southern California Branch of American Society for Microbiology(SCASM) Poster Award, covering travel to ASM General Meeting2015 in New Orleans.

Publications and Posters:Kim, B. J.; Hancock, B. M.; Bermudez, A.; Del Cid, N.; Reyes, E.; vanSorge, N. M.; Lauth, X.; Smurthwaite, C. A.; Hilton, B. J.; Stotland, A.;Banerjee, A.; Buchanan, J.; Wolkowicz, R.; Traver, D.; Doran, K. S.,Bacterial induction of Snail1 contributes to blood-brain barrierdisruption. J Clin Invest 2015, 125 (6), 2473-83; (b)

Kim, B. J.; Hancock, B. M.; Del Cid, N.; Bermudez, A.; Traver, D.; Doran, K.S., Streptococcus agalactiae infection in zebrafish larvae. Microb Pathog2015, 79, 57-60.

Hancock, B. M., Group B Streptococcus induces the host transcriptionalfactor, Snail1, to penetrate the blood-brain-barrier. American Society forMicrobiology 115th General Meeting. 2015. New Orleans, LA.

Hancock B.M., Development of Zebrafish Models of StreptococcalInfection to Examine Host Pathogen Interactions and DiseaseProgression. International Conference on Gram Positive Pathogens.2014. Omaha, NE.

DANIEL HOFFUniversity of California San DiegoDepartment of Mathematics

Degrees:C.Phil. in Mathematics, University ofCalifornia, San Diego

M.A. in Mathematics, University of California, San Diego

B.S. in Mathematics, University of Minnesota, Twin Cities

Scholar Sponsor:ARCS Foundation

About the Scholar:The current focus of Daniel’s research centers on studyingrigidity in a class of abstract mathematical objects called vonNeumann algebras, which arose from the study of the physicaltheory of quantum mechanics. These von Neumann algebrascan be constructed from certain other well-studied mathe-matical objects, and rigidity refers to the extent to which theassociated von Neumann algebra “remembers” the originalobject. In some cases, the von Neumann algebra completely“remembers” the original object, while in others, it completely“forgets.” Daniel enjoys running, swimming, backpacking, andmany other outdoor activities.

Benefits to Society:Theoretical physics provides the original motivation for the studyof von Neumann algebras as they arose from the study ofquantum mechanics. The implications (such as technologicalinnovations) of any physical theory built upon von Neumannalgebras would depend upon our mathematical understanding oftheir properties. However, this is just one possible direction ofsocietal benefit; as usual with mathematics research, the mostimportant consequences of this mathematical foundation may bediscovered far in the future.

Awards and Honors:National Science Foundation Graduate Research FellowshipJames B. Ax Fellowship

Publications and Posters:Hoff, D.J. Von Neumann Algebras of Equivalence Relations withNontrivial One-Cohomology. submitted, preprintarXiv:1506.00588. 2015.

Hoff, D.J., Olver, P.J. Automatic Solution of Jigsaw Puzzles. J.Math. Imaging Vision. 2014, 49 (1), 234-250.

Hoff, D.J., Olver, P.J. Extensions of Invariant Signatures forObject Recognition. J. Math. Imaging Vision. 2013, 45 (2), 176-185.

Hoff, D.J., Johnson, C. R., Nasserasr, S. Totally Positive Shapesand TPk-Completable Patterns. Linear Algebra Appl. 2012, 436(12), 4412-4422.

Page 17: ARCS® Foundation, Inc., San Diego Chapter

LAUREN HOFFMANUniversity of San DiegoShiley-Marcos School of Engineering

Scholar Sponsor:WD-40 Company

About the Scholar:Last January Lauren traveled to the Dominican Republic with a groupof engineering students from USD with the goal of installingchlorinators for drinking water sanitation and fuel-efficient stoves inthe community of El Cercado. Upon returning to San Diego, she tookon the project of designing a hot water shower for the community. Herobjective was to create a passive solar heating system that could raisewater temperature to 100ºF. After online research, she built twodifferent prototypes and has been testing variations of each in order todevelop a design that maximizes efficiency while minimizing cost.Outside of school, Lauren surfs and plays the violin.

Benefits to Society:During her visit in El Cercado, she discovered the community had adesire for implementation of hot water showers, not only to serve as aluxury, but also to help with medical issues. A group of nursestraveling with her group verified that bathing in cold water can lead toworsening illness as energy is drained from the body. It also is a hopethat having hot showers will increase sanitation and prevent illness inthe first place, as community members will be more likely to washeach day.

Awards and Honors:Alcala Award – Annual merit scholarship from University of San Diego.Dean’s List, First Honors – Excellent academic standing, withGPA above 3.5 for Fall 2011 and Fall 2012 – Spring 2015semesters.

EIREN JACOBSONUniversity of California, San DiegoScripps Institution of Oceanography

Degrees:M.S. in Oceanography, University ofCalifornia, San Diego

B.A. in Environmental Biology, Columbia College, Columbia University in the City ofNew York

Scholar Sponsor:Kenneth and Marjorie Blanchard

About the Scholar:Eiren is broadly interested in quantitative approaches to whale,dolphin, and porpoise population studies using innovativetechniques and technologies. Her doctoral dissertation project isto develop new methods for monitoring harbor porpoisepopulations in California. Harbor porpoise populations arecurrently monitored using aerial surveys; however, these surveysare dangerous, expensive, and weather-dependent. Becauseharbor porpoises produce echolocation clicks in order tonavigate and to forage, they can also be studied usingunderwater microphones called hydrophones. For herdissertation, she is working to assess the feasibility of usinghydrophone networks for long-term monitoring of harborporpoise populations in California. Eiren enjoys hiking, rockclimbing, running, cooking, and reading in her spare time.

Benefits to Society:Eiren collaborates closely with scientists at the National Oceanic andAtmospheric Administration to ensure that her research objectivesare directly relevant to the management and conservation of harborporpoises. By providing an effective tool for monitoring harborporpoise populations over time, her research will allowanthropogenic threats to the harbor porpoise, including pollution,noise, and fishery interactions, to be quickly recognized andaddressed, thereby aiding in long-term conservation efforts.Additionally, her research will improve the efficiency of harborporpoise monitoring, resulting in higher-quality data, using saferand less-expensive methods.

Awards and Honors:E. W. Fager Award for Outstanding Contributions toQuantitative Education at SIO (2015)Mia J.Tegner Memorial Fellowship in Coastal Ecology (2015)National Science Foundation Graduate Research Fellowship(2012)National Science Foundation Integrative Graduate Educationand ResearchTraineeship (2012)National Merit Scholarship (2006)

Publications and Posters:Jacobson, E. K.; Yack, T. M.; Barlow, J. Evaluation of anautomated acoustic beaked whale detection algorithm usingmultiple validation and assessment methods; NOAA-TM-NMFS-SWFSC-509; SWFSC: La Jolla, CA, 2013.

Jacobson, E. K.; Forney, K. A.; Harvey, J. T. Acoustic evidencethat harbor porpoises (Phocoena phocoena) avoid bottlenosedolphins (Tursiops truncatus). Marine Mammal Science 2015,31, 386-397.

Jacobson, E. K.; Forney, K. A.; Harvey, J. T. Evaluation of apassive acoustic monitoring network for harbor porpoise inCalifornia; CEC-500-2015-XXX; CEC: Sacramento, CA, In Press.

Jacobson, E. K.; Forney, K. A.; Barlow, J. Paired surveyparameter estimation: Using visual survey data to estimatepassive acoustic detection parameters for harbor porpoiseabundance estimates. In Preparation.

15

Page 18: ARCS® Foundation, Inc., San Diego Chapter

16

DAISY JOHNSONThe Scripps Research Institute Kellogg School of Science and Technology

Degrees:M.S. in Biomedical Sciences, Texas A&MUniversity

B.S. in Biological Sciences, Cornell Univ.

Scholar Sponsors:Webster and Helen Kinnaird/Paul Bechtner

About the Scholar:The Havran lab has identified protein interactions that are importantfor normal wound healing to occur and which are dampened in thetissue surrounding chronic wounds. The goal of Daisy’s project is tomanipulate these protein interactions for therapeutic benefit. They arecollaborating with the Finn Lab at Georgia Tech to contain theseproteins in hydrogels with finely tuned release rates (from minutes tomonths) that will allow treatment over a specific period of time. Usingthis method of product release, she will evaluate the ability of theseproteins to improve wound repair in vitro and in vivo. Daisy’sinterests outside of the lab include cross-country skiing, hiking, andriding horses.

Benefits to Society:Chronic wounds, such as pressure sores in elderly patients and footulcers in diabetic patients, are an increasing problem. Currentlytreatment options are limited and often involve debridement(removing non-healing tissue from around the edges of the wound).Any therapeutic benefit shown through this project would bepotentially useful in treating non-healing wounds. Additionally, thedevelopment, with the Finn lab, of a delivery system for treating skinlesions over variable time frames has clinical and scientificapplications.

Awards and Honors:Lechner Scholar, Texas A&M University

Texas A&M College of Veterinary Medicine Graduate StudentResearchTrainee Award

Publications and Posters:Steelman, S.M; Johnson, D; Wagner, B.; Stokes, A.; Chowdhary, B.P.Cellular and Humoral Immunity in Chronic Equine Laminitis. Vet.Immunol. Immunopathol. 2013, 153, 217-226.

Rasmann, S.; Johnson, M.D.; Agrawal, A.A. Induced responses toHerbivory and Jasmonate in Three Milkweed Species. J. Chem. Ecol.2009, 35, 1326-1334.

MAGGIE JOHNSONUniversity of California San DiegoScripps Institution of Oceanography

Degrees:M.S. in Biology, California StateUniversity, Northridge

Professional M.S. in Marine Biology, Northeastern University

B.A. in Biology, Colby College

Scholar Sponsors:Carlos and Sharon Arbelaez

About the Scholar:Maggie is interested in understanding how coral reefs will beimpacted by changing ocean acidity due to increasingatmospheric carbon dioxide, a process known as oceanacidification. For her dissertation research she is conducting aseries of experiments to test the effect of carbon dioxide on coralreef seaweeds. In healthy reef systems, or those not impacted bypollution and overfishing, reef seaweeds are an important sourceof food and energy for coral reef organisms. The objectives ofher research are: 1) to understand how changing oceanchemistry due to increasing carbon dioxide emissions affectscoral reef seaweeds, and 2) to understand the role seaweedsmay play in mediating the effects of increasing carbon dioxideon other reef organisms. SCUBA diving, gardening, painting andsilkscreening are among Maggie’s outside interests.

Benefits to Society:The goal of Maggie’s research is to quantify the impacts of oceanacidification on critical foundation species on coral reefs. The datawill provide information on the extent that ocean acidification haspositive, negative or no effect on a variety of coral reef seaweeds,and on how ocean acidification impacts growth rates,photosynthesis and organic and inorganic production by seaweeds.The potential benefits to society will be in how this information isrelayed to the parties responsible for policy and managementdecisions on coral reefs. By identifying species or even genera thatare threatened by ocean acidification, information can be providedto conservation managers that inform local management strategies,ultimately working toward healthy, surviving coral reefs. Healthycoral reefs mean more money, jobs and food for coastal nations thatrely directly on coral reef resources.

Awards and Honors:Edna Bailey Sussman Foundation AwardScripps Institution of Oceanography, Graduate Student Excellence Award International Women in Fishing Association Scholarship Outstanding Graduate Research Award, California State University,Northridge Department of BiologySally Casanova California Pre-Doctoral Award, California StateUniversity, Northridge

Publications and Posters:Johnson, M. D.; Price, N. N.; Smith, J. E. Contrasting effects of oceanacidification on tropical fleshy and calcareous algae. PeerJ. 2014, 2, e411,http://dx.doi.org/10.7717/peerj.411.

Johnson, M. D.; Moriarty, V. W.; Carpenter R. C. Acclimatization of thecrustose coralline alga Porolithon onkodes to variable pCO2. PloS One.2014, 9, e87678.

Williams, G. J.; Price, N. N.; Ushijima, B.; Aeby, G. S.; Callahan, S.; Davy,S. K.; Gove, J. M.; Johnson, M. D.; Knapp, I. S.; Shore-Maggio, A.; Smith,J. E.; Videau, P.; Work, T. M. Ocean warming and acidification havecomplex interactive effects on the dynamics of a marine fungal disease.Proc. R. Soc., B, 2014, 281, 20133069.

Johnson, M. D.; Carpenter, R. C. Ocean acidification and warmingdecrease calcification in the crustose coralline alga Hydrolithon onkodesand increase susceptibility to grazing. J. Exp. Mar. Biol. Ecol. 2012, 434,94-101.

Page 19: ARCS® Foundation, Inc., San Diego Chapter

DEANNA JOHNSTONUniversity of San DiegoHahn School of Nursing and HealthSciences

Degrees:M.S. in Nursing, San Diego StateUniversity, San Diego, CA

B.S. in Nursing, San Jose State University, San Jose, CA

Scholar Sponsor:Hervey Family Non-Endowment Fund

About the Scholar:Deanna plans to conduct research related to utilizing PalliativeCare for chronically ill patients from the Hispanic or Latinopatient population. The Hispanic and Latino populations havea cultural view that an illness is not to be talked about,preventing these populations from receiving the best care.Palliative Care has often been mistaken for Hospice or end-of-life care. Now, the emphasis for Palliative Care has revertedback to its roots as a resource for any patient with anincurable, chronic illness. Palliative Care consists of a team ofnurses, physicians, social workers, chaplains and othermembers to ensure that all patients, no matter their diseasestage, have the resources available to maintain a good qualityof life. Deanna enjoys reading, teaching, traveling, beinganywhere near the ocean, sewing and spending as much timeas she can with her family.

Benefits to Society:Deanna’s proposed research would greatly improve the healthoutcomes of the Hispanic and Latino populations as well asdecrease the length of stay and readmissions for patients withchronic illnesses. She believes that this research will betranslatable to other patient populations and keep morepatients out of the hospital. This decrease in hospitalizationswill help the ED care for patients who truly need the emergencycare as well as keep patients at home with their families.

Awards and Honors:Sharp Healthcare - Center of Nursing Excellence Award fordesignating two Progressive Care Units as specialty units. Datashowed that by designating one Progressive Care unit as aStroke Specialty Unit and the other as a Pre/Post Open HeartSurgery Progressive Care, the care of patients greatly improvedand patients stayed in the hospital less time.

Sharp Healthcare - Center of Nursing Excellence Award forobtaining Gold Status for Core Measures in Stroke Care.

TREVOR JOYCEUniversity of California, San DiegoScripps Institution of Oceanography

Degrees:B.S. in Biology, University of AlaskaSoutheast

Scholar Sponsor:Virginia Lynch Grady Endowment

About the Scholar:Many tropical seabirds hunt and scavenge prey in a close associationwith tunas and dolphins. These predators corral prey and force it tothe surface making it available to seabirds. Intensifying industrialharvests of yellow-fin and skipjack tunas as well as the depletion ofdolphin stocks in the tropical Eastern Pacific Ocean over the last 50years have potentially disrupted this relationship. Trevor’s dissertationresearch uses several unique datasets of seabird observations fromresearch vessels over the last thirty years to document changes in theabundance, composition, and size of seabird flocks and populations inrelation to the tuna harvest levels and climatic variability.Trevor enjoysphotographing landscapes and wildlife and learning about the naturalhistory of his surroundings. Living and working near the beach affordshim the chance to surf and mountain bike.

Benefits to Society:Seabirds often play important but overlooked roles in ecosystems andprovide frequently underappreciated benefits to people. Trevor’sresearch focuses on understanding the conservation status andvulnerability of many tropical seabirds to human changes in marineenvironments. Through these efforts he hopes to maintain their valueto people such as recreational and artisanal fishermen who rely ontropical seabirds to find fish schools, a role that holds great culturalsignificance to many Pacific Island peoples. Finally, seabirds alsoprovide a unique way of measuring long-term ecosystem health.

Awards and Honors:National Science Foundation, Graduate Research FellowshipMichael Mullin FellowshipPacific Seabird Group, Best Student Poster Award, 39th Pacific

Seabird Group Annual MeetingResearch Corporation of the University of Hawaii, Outstanding

Employee of the Year AwardNational Science Foundation, Research Experience for

Undergraduates

Publications and Posters:Joyce, T.W.; Eifler, D.A.; Powell, R.D. Variable habitat use influences themating system of a Lesser Antillean anole. Amphibia-Reptilia 2010, 31,395-401.

Joyce T.W. Abundance estimates of the Hawaiian Petrel (Pterodromasandwichensis) and Newell’s Shearwater (Puffinus newelli) based on datacollected at sea, 1998-2011. Technical Report to U.S. Fish and WildlifeService, 2013.

Joyce, T.W.; Ballance L.T. Model-based abundance estimates of theHawaiian Petrel (Pterodroma sandwichensis) and Newell’s Shearwater(Puffinus newelli) based on data collected at sea, 1998-2011. PacificSeabird Group Annual Meeting, Portland, OR, Feb. 20-24, 2013.

Joyce, T.W.; Holmes, N.D.; Ballance L.T. Breeding season marinedistribution and spatial habitat use of the Newell’s shearwater from Kauai,Hawaii. Poster Presentation. Pacific Seabird Group Annual Meeting, TurtleBay, HI, Feb. 7-11, 2012.

17

Page 20: ARCS® Foundation, Inc., San Diego Chapter

18

ASHOK KODIGALAUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Electrical and ComputerEngineering (Electronics & Photonics),University of California, Santa Barbara

B.S. in Electrical Engineering, University of California, Santa Barbara

Scholar Sponsor:Ellen Browning Scripps Foundation

About the Scholar:Ashok is exploring the physics of localized plasmonicresonances in metals at nanoscale dimensions to ultimatelydevelop an optical biosensor for quick on-chip pathogendetection. Plasmonic particles’ small size makes them ideallysuited for sensing at the molecular scale with a high degree ofsensitivity. Concurrently, he also is working on designing highquality (high-Q) factor optical cavities using semiconductormaterials (ex. InGaAs) to serve as laser sources in the nearinfrared (IR) regime. The higher the quality factor, the morepower efficient is the laser. In his spare time, Ashok enjoysroad biking and various beach activities.

Benefits to Society:Plasmonic sensors have the potential for numerousapplications in the field of medicine and life sciences such asthe prevention of pathogen dissemination. The ability to quickly(lab-on-chip) and effectively (high sensitivity) identifypathogens will serve as a superior barrier against theirspread. This research on plasmonic sensors will directlycontribute to the healthcare industry in the form of a low-costdiagnostic and prevention tool. These sensors can be tailored todetect other elements such as air-borne toxins, pesticides,water contaminants, etc..

Awards and Honors:ECE Graduate Student Fellowship, UC San Diego

Steve Leung Memorial Engineering Scholarship, UC SantaBarbara

Publications and Posters:Kodigala, A.; Lepetit, T.; Kanté, B. Engineering ResonanceDynamics of Plasmon Hybridized Systems. J. Appl. Phys. 2015,117, 023110.

Lepetit, T.; Gu, Q., Kodigala, A.; Bahari, B.; Fainman, Y.; Kanté, B.Resonantly Trapped Bound State in the Continuum Laser. arXiv[Online] 2015, 1508.05164.

Chen, A.; Kodigala, A.; Lepetit, T.; Kanté, B. Multipoles ofeven/odd split-ring resonators. Photonics 2015, 2, 883-892.

Kodigala, A.; Lepetit, T.; Kanté, B. Controlling Resonances vianear-field interactions in Plasmonics. Materials ResearchSociety (MRS) Conference Spring, San Francisco, CA; April 8,2015.

ADITYA KUMARUniversity of California, San DiegoJacobs School of Engineering

Degrees:B.S. in Bioengineering, Rice University

Scholar Sponsors:Roche/ARCS Foundation Scholar Award

About the Scholar:Aditya is working on the development of a novel "disease-in-a-dish" niche which mirrors the dynamic extracellular changesthat occur during myocardial infarction (MI). This niche will beused to identify novel pathways that could result in potentialtherapeutic solutions for the treatment and prevention of MI. Inaddition, Aditya is culturing patient-specific induced pluripotentstem cell-derived cardiomyocytes on this niche to better assesspotential genetic susceptibility toward MI. Outside of lab,Aditya enjoys exercising and playing basketball.

Benefits to Society:Myocardial infarction represents the leading cause of death inthe United States. Therapeutic treatments are limited due to theinability to replicate the environmental changes associated withMI progression, namely the dynamic increase in stiffness of theinfarcted tissue compared to the surrounding healthy tissue.The development of this novel biological substrate, coupledwith stem cell-derived cardiomyocytes, allows for betterunderstanding of altered cellular behavior in response to MIprogression in addition to providing a platform for drug testing.

Awards and Honors:National Science Foundation Graduate Research Fellowship

Distinction in Research and Creative Works, Rice University

Publications and Posters:Wiltz, D. W.; Han, R. I.; Wilson, R. L.; Kumar, A.; Morrisett, J. D.;Grande-Allen, K. J. Differential Aortic and Mitral ValveInterstitial Cell Mineralization and the Induction ofMineralization by Lysophosphatidylcholine In Vitro. Cardiovasc.Eng. Technol. 2014, 5(4), 371-383.

Kumar, A.; Wiltz, D. W.; Grande-Allen, K. J. Gentamicin ReducesCalcific Nodule Formation by Aortic Valve Interstitial Cells InVitro. Cardiovasc. Eng. Technol. 2013, 4(1), 16-25.

Kumar, A.; Wiltz, D. W.; Grande-Allen, K. J. In Vitro Modeling ofthe Effect of Gentamicin on Aortic Valve Interstitial Cell Calcifi-cation. Tissue Engineering & Regenerative Medicine InternationalSociety Conference, Houston, TX. December 12, 2011.

Page 21: ARCS® Foundation, Inc., San Diego Chapter

DAVID LEONUniversity of California, San DiegoCenter for Astrophysics and Space Sciences

Degrees:M.S. in Physics, University of California,San Diego

B.S. in Physics, California Institute of Technology

Scholar Sponsor:Virginia Lynch Grady Endowment

About the Scholar:David’s research group is part of the Polarbear collaboration. Itstudies the Cosmic Microwave Background, which is light fromthe early universe that was first emitted when the universecooled enough to form Hydrogen atoms. This light travelsthrough the universe, mostly unperturbed, until detected in thepresent day by a telescope in the Atacama Desert in Chile.David is currently analyzing polarization data from the first twoyears of observations to determine the amount of gravitationallensing that this light has experienced as it passed throughspace to reach us. David enjoys writing fiction/poetry, archery,badminton, and travel.

Benefits to Society:Researching the Cosmic Microwave Background is a promisingarea for insights into fundamental physics. Analysis ofgravitational lensing using next-gen instruments coulddetermine the neutrino mass hierarchy, a longstanding problemin fundamental particle physics. Detection of B-modepolarization would be a smoking gun for inflation, the leadingtheory of physics right after the big bang; not even the LHC canprobe energies at this scale. Finally, detection of polarizationrotation could provide clues on exotic Lorentz violating physics.

Awards and Honors:Caltech President's Scholarship

UCSD Physics Excellence Award

Attended OSG User School at UW-Madison

MONIQUE A. LINEBACKUniversity of San DiegoHahn School of Nursing and Health Science

Degrees:M.S.N. in Nursing, University of San Diego

A.D.N. in Nursing, Palomar College, San Marcos

B.A. in Critical Gender Studies, University of California, San Diego

Scholar Sponsor:The Beyster Family Foundation Fund IV

About the Scholar:Monique’s goal is to identify strategies that will promote healthin vulnerable populations. Her experience with her own familyhas reinforced the importance of the role of mothers inpromoting the health of their children through diet, exercise,other positive health practices and family support. However,many women are unaware of these health practices and lackaccess to information regarding health promotion strategies.Her research aim is to increase women’s’ awareness of theimportance of positive health practices to improve healthoutcomes for themselves and their families. She is in theprocess of refining her research focus and developing theconceptual framework and specific identifying variablesappropriate for this research focus. Her experience as a nursein the critical care unit has increased her awareness of the needfor developing a healthy lifestyle and preventing chronic illnessor mediating the negative effects of such illnesses whenpossible; however, many women face barriers to achieving ahealthy lifestyle for themselves and their families. These can besocioeconomic factors, lack of education, environmental risk-factors, and/or lack of access to health care. Monique intends tofocus on women with HIV who are experiencing healthdisparities, identify barriers to achieving healthy outcomes anddevelop strategies that can improve the health of these womenand their families.

Benefits to Society:Women are the major health brokers of their families in termsof life-style, eating habits, stress reduction and other factors ofdaily living; however, many women continue to experiencebarriers to obtaining information regarding lifestyle changesthat could improve health outcomes as well as limited accessto health care. Although there is a significant body of researchrelated to health promotion and behavior change, it frequentlydoes not address the unique needs of women who may bedisadvantaged by race, ethnicity, sociocultural factors,economic status or other factors that increase healthdisparities. If these barriers could be identified for a specificgroup of women, then more effective strategies for healthpromotion interventions could be developed and evaluated foreffectiveness.

Awards and Honors:Nurse Traineeship Award

Nurse Faculty Loan Forgiveness Program Award

19

Page 22: ARCS® Foundation, Inc., San Diego Chapter

SEAN MADDOXSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Chemistry, University of California,Davis

Scholar Sponsor:Dottie Georgens

About the Scholar:Sean’s research aims to discover new transformations inorganic chemistry that can be used to aid in the discovery ofpotent drugs for the treatment of disease. He is currentlystudying different methods of inserting chlorine atoms intodrug scaffolds. The addition of chlorine into these smallmolecules can have a large effect on the molecule’s structure aswell as its electronic properties. This transformation also isused to structurally rigidify promiscuous small molecule drugsto increase their potency and possibly decrease unwanted sideeffects. When not in the lab, Sean enjoys golf.

Benefits to Society:

Sean’s research is fundamentally entrenched in the field of drug

design. The discoveries from his lab show promise toward the

design of more selective kinase inhibitors, which are not very

selective toward their respective targets, many often inhibiting

30 or more kinases. Being one of the first to utilize Lewis base

catalyzed chlorination, Sean aims to thoroughly study the

mechanistic principles of this catalysis to allow this chemistry

to be easily implemented into any research laboratory.

Publications and Posters:Maddox, S. M.; Nalbandian, C. J.; Smith, D. E.; Gustafson, J. L.A Practical Lewis Base Catalyzed Electrophilic Chlorination ofArenes and Heterocycles. Org. Lett. 2015, 17, 1042.

Luca, O. R.; Gustafson, J. L.; Maddox, S. M.; Fenwick, A. Q.;Smith, D. C. Catalysis by electrons and holes: formal potentialscales and preparative organic electrochemistry. Org. Chem.Front. 2015, 2, 823.

PAUL MAIERSan Diego State University Joint Doctoral Program in EvolutionaryBiology, College of SciencesDegrees:B.S. in Ecology, Evolution, and AquaticBiology, University of California, Santa Barbara

Scholar Sponsor:Thomas C. Ackerman Foundation

About the Scholar:The overarching goal of Paul’s dissertation research is tounderstand the interfacing roles of migration, adaptation, andplasticity in shaping the persistence of natural populations.Specifically, he is interested in developing novel network-analytical Yosemite Toad tools to model the evolution ofamphibians across isolated alpine meadows. His researchobjectives include two themes. First, he will apply these novelmodels in a conservation genetic framework to assist inmitigation in species recovery plans. Secondly, he will elucidateevolutionary genomic features of ecological specialists. Histhesis will explore the hypothesis that ecological specialists andgeneralists mount different evolutionary responses to the sameselection pressures. Paul enjoys endurance sports (e.g.running, cycling, rowing), mountaineering, aviation, drumming,herpetology, macro photography, and martial arts.

Benefits to Society:Landscape genetics is the study of environmentally mediatedevolution, including connectivity, population persistence, localadaptation, and genetic rescue. Paul’s research will bear on theevolutionary history and future of the Yosemite Toad (Anaxyruscanorus), and his results will have significant utility forprioritizing the future management and conservation of thisiconic California native. Additionally, our understanding of howecological specialists evolve will help prioritize translocations,assisted migration, and captive breeding programs for manyspecies worldwide.

Awards and Honors:Jordan D. Covin Memorial Scholarship

Harold & June Grant Memorial Scholarship

USGS Conservation Genetics Assistantship

Eugene Cota-Robles Fellowship

Honor Society of Phi Kappa Phi

Publications and Posters:Maier P; Ostoja S.; Vandergast A.; Aguilar A.; Bohonak A.; A NovelGenetic Network Model Predicts Range Shifts in Response to ClimateChange for Yosemite Toads (Anaxyrus [Bufo] canorus). Mol. Ecol. 2015,in prep.

Ostoja S.; Matchett J.; McKenny H.; Brooks M.; Berlow E.; Knapp R.;Maier P.; Danielle N. Yosemite Toad (Anaxyrus [Bufo] canorus) BreedingOccupancy of Meadows in Yosemite and Kings Canyon National Parks,California. Herp. Con. Bio. 2015, in prep.

Klinger R.; Cleaver M.; Anderson S.; Maier P.; Clark J. Implications ofScale-independent Habitat Specialization on Persistence of a RareSmall Mammal. Global Ecol. Con. 2015, 3, 100-114.

Rosso A.; Maier P.; Ostoja S.; Aguilar A. Conservation Genetics ofYosemite Toads in Sequoia Kings National Park, UC Merced, Merced, CA.

20

Page 23: ARCS® Foundation, Inc., San Diego Chapter

21

FREDERICK MATSUDAUniversity of California, San Diego Center for Astrophysics and Space Sciences

Degrees:B.A. in Astrophysics, B.A. in Physics,University of California, Berkeley

Scholar Sponsors:ARCS Foundation/Karen & Bob Bowden

About the Scholar:Frederick is researching the physics of the early universethrough observing remnant light left over from the Big Bang.He is a member of the POLARBEAR experiment and has helpeddevelop a radio telescope located in San Pedro de Atacama,Chile. With this telescope, he is researching to detect apolarized signal that can potentially be the strongest evidenceor proof of a widely accepted and mainstream theory of thebeginning of our universe, the Big Bang theory. When notstargazing, Frederick likes cooking and wine.

Benefits to Society:Frederick’s research will further the understanding of theorigins of the universe. This research will influence and giverise to further research not only in cosmology but also in manyother physics fields. Inflationary cosmology involves allfundamental physics such as general relativity, quantummechanics, and statistical mechanics. Understanding the BigBang allows us to further enhance and develop the theories ofall fundamental physics, which in turn influence technologicaladvancement as well.

Awards and Honors:Inamori Fellowship

UCSD Graduate Research Fellowship

UCSD Physics Excellence Award

Undergraduate Research Apprentice Program SummerEmployment Award

Publications and Posters:POLARBEAR Collaboration. Measurement of the Cosmic MicrowaveBackground Polarization Lensing Power Spectrum with the POLARBEARExperiment. Physical Review Letters. July 2014, 113, 021301.

POLARBEAR Collaboration. A Measurement of the Cosmic MicrowaveBackground B-Mode Polarization Power Spectrum at Sub-DegreeScales with POLARBEAR. The Astrophysical Journal. October 2014,794, 171.

POLARBEAR Collaboration. Evidence for Gravitational Lensing of theCosmic Microwave Background Polarization from Cross-Correlationwith the Cosmic Infrared Background. Physical Review Letters. April2014, 112, 131302.

T.Tomaru et al. The POLARBEAR-2 Experiment. Millimeter,Submillimeter, and Far-Infrared Detectors and Instrumentation forAstronomy VI. Proc. SPIE 8452.

MEGAN MONSANTOJoint Doctoral Program at San Diego StateUniversity and University of California,San DiegoCell and Molecular Biology Program

Degrees:B.S. in Genetics, Clemson University

Scholar Sponsor:Hervey Family Non-Endowment Fund

About the Scholar:Megan joined Dr. Mark Sussman’s research laboratory wherework focuses on cardiac stem cells in hope of treating patientswith heart disease. Her graduate project involves isolatingnovel stem cells from the human heart with the idea ofcombining these distinct stem cells in a defined manner toconstruct a three-dimensional structure that has been termed a“CardioCluster”. The belief is that by rationally creating astructure that incorporates the potential provided by each ofthese stem cells, CardioClusters will improve regeneration ofdamaged heart tissue above and beyond anything currentlyseen in the cardiac field. Megan loves to be outdoors - hiking,fishing, snorkeling, and spending time with her dog. She alsoenjoys woodcarving as well as drawing and painting.

Benefits to Society:Current limitations with cardiac stem cell therapy include poorengraftment and low survival rates, leading to loss of cell-to-cell communication. Megan’s graduate project addresses thesechallenges by creating what are termed CardioClusters. Bycombining three diverse stem cells populations to create aCardioCluster, the overall structure is larger and allows fordirect cell contact. The hope is that CardioClusters will enhancecellular communication and regenerative capacity compared tocurrent single, stem cell-based therapies.

Awards and Honors:NIH-R01 Co-investigator “Enhanced Myocardial Repair withCardioClusters and CardioChimeras"AHA Cardiovascular Disease Student ScholarshipGordon Conference Best Graduate Student Poster AwardCSUPERB Travel AwardBiology Department Outstanding Graduate Teaching Assistant

Publications and Posters:Monsanto, M.; Sussman, M.A. Myocardial Infarct Scar: Hunting Downthe Responsible Cells, But Then What? J Am Coll Cardiol. 2015,65(19):2067-2069.Samse, K.; Emathinger, J.; Hariharan, N.; Quijada, P.; Völkers, M.;Ormachea L, De La Torre, A.; Alvarez, R.; Din, S.; Mohsin, S.; Monsanto,M.; Fischer, KM.; Dembitsky, W.P.; and Sussman, M.A. Functional effectof Pim1 depends upon intracellular localization in human cardiacprogenitor cells. J Biol Chem. 2015, 290(22):13935-47.Hariharan, N.; Quijada, P.; Mohsin, S.; Joyo, A.Y.; Samse, K.M.;Monsanto, M.; De La Torre, A.; Avitabile, D.; Ormachea, L.; McGregor,M.J.; Tsai, E.; Sussman, M.A. Nucleostemin rejuvenates cardiacprogenitor cells and antagonizes myocardial aging. J Am Coll Cardiol.2015, 65(2):133-47.Mohsin, S.; Khan, M.; Nguyen, J.; Alkatib, M.; Siddiqi, S.; Hariharan, N.;Wallach, K.; Monsanto, M.; Gude, N.A.; Dembitsky, W.P.; Sussman, M.A.Rejuvenation of Human Cardiac Progenitor Cells with Pim-1 Kinase. CircRes. 2013, 113(10):1169-79.

Page 24: ARCS® Foundation, Inc., San Diego Chapter

22

TIM MONTGOMERYSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Chemistry, The College of Williamand Mary

Scholar Sponsor:Tyler & Diane Miller

About the Scholar:Tim’s current research focuses on developing new chemicalmethodologies and their application toward more efficient,economic, and “greener” synthetic routes of natural productcompounds. He is currently using new copper methodology tohelp aid in synthesizing the natural product azaspirene.Azaspirene is an angiogenesis inhibitor that is shown to inhibitblood vessel growth in tumors without effecting normal cells inthe body. Combined with the low toxicity of this compound, itis a perfect candidate as a new and milder anti-cancer drug.The end goal is to produce ample amounts of thesecompounds for aid in drug development studies. Tim’s hobbiesinclude surfing, fishing and playing the drums.

Benefits to Society:Tim’s research benefits society by supporting efficient,economic and “greener” synthetic routes for newtherapeutically active natural product compounds to facilitatedrug development. New natural product compounds areconstantly being discovered that show potential as new drugcompounds; however, obtaining an ample amount of thesenovel, natural product compounds can be problematic. Anabundant supply of a new drug compound is necessary toundergo the rigorous drug development process required forthese compounds to become commercialized drugs.

Publications and Posters:Schmit, D.; Barker, M.; Montgomery, T.; Mendez, Y.; Bergdahl, M.Diversity Oriented Total Synthesis of Pseurotin Analogs:Powerful Inhibitors of Angiogenesis and Inflammation, 2012CSU Biotechnology Symposium, Santa Clara, CA, January 2012.

STEVEN NALEWAYUniversity of California, San DiegoMaterials Science and EngineeringProgram, Jacobs School of Engineering

Degrees:M.S. in Materials Science, Oregon State University

B.S. in Mechanical Engineering, Oregon State University

Scholar Sponsor:Legler Benbough Foundation

About the Scholar:Steven’s research focuses upon understanding and takinginspiration from nature in the form of the interconnected fieldsof biological materials science and bioinspired design. Throughbiological materials science, he studies the unusual armor ofthe boxfish, which unlike many fish, defends itself with a rigidcarapace of scutes that feature a complex layered arrangementof protein fibers and a rigid mineral plate. Through bioinspireddesign, he creates designs like the layered structure of theboxfish using a method called freeze casting. Through thismethod he can create composites that can be employed forstructural or biomedical applications. Stephen enjoys spendingtime with his wife and two dogs as well as relaxing at the LaJolla Shores.

Benefits to Society:Stephen’s work into freeze casting has the potential to beimplemented into biomedical bone implants. He has developeda novel technique in order to better mimic the complex porousstructure of bone and, along with collaborators, is investigatingthe biocompatibility of these structures. These materials couldbe implemented in order to create degradable bone implants,which would provide stability directly after an injury, but thendegrade over time allowing for healthy bone to take its place.

Awards and Honors:2015-2016 Bernard and Sophia Gordon Engineering LeadershipCenter Scholar. Awarded by the University of California, San Diego.2015 Peer Mentorship GSA Community Award. Awarded by theUniversity of California, San Diego.2015 Abe Hurlich Award. Awarded by ASM International.2013 Outstanding Mechanical Engineering Graduate TeachingAssistant. Awarded by Oregon State University.2012 - 2013 Samuel H. and Violet F. Graf Research Fellowship.Awarded by Oregon State University.

Publications and Posters:Naleway, S. E.; Porter, M. M.; McKittrick, J.; Meyers, M. A. StructuralDesign Elements in Biological Materials: Application toBioinspiration. Adv. Mater. [Online early access]. DOI:10.1002/adma.201502403. Published online: Aug 25, 2015.http://onlinelibrary.wiley.com/doi/10.1002/adma.201502403/full.Naleway, S. E.; Yu, C. F.; Porter, M. M.; Sengupta, A.; Iovine, P. M.;Meyers, M. A.; McKittrick, J. Bioinspired Composites from FreezeCasting using Clathrate Hydrates. Mater. Des. 2015, 71, 62-67.Naleway, S. E.; Lear, W.; Kruzic, J. J.; Maughan, C. B. MechanicalProperties of Suture Materials in General and Cutaneous Surgery. J.Biomed. Mater. Res., Part B 2015, 103B, 735–742.Naleway, S. E.; Greene, R. B.; Gludovatz, B.; Dave, N. K. N.; Ritchie, R.O.; Kruzic, J. J. A Highly Fatigue-Resistant Zr-Based Bulk MetallicGlass. Metall. Mater. Trans. A 2013, 44A, 5688-5693.

Page 25: ARCS® Foundation, Inc., San Diego Chapter

23

EMILY NARDONIUniversity of California, San DiegoDepartment of Physics

Degrees:B.S. in Physics, Massachusetts Institute ofTechnology

Scholar Sponsor:Ellen Browning Scripps Foundation

About the Scholar:Emily is interested in studying the mathematical structure ofthe most fundamental theories of nature--theories of particlephysics. To this end, she studies the framework of quantumfield theory, which is one of the most accurate in modernphysics and best describes particle physics. There are still manyconceptual gaps in our understanding of quantum field theorywhich she hopes her research can help close. By trying tounderstand the language in which physical theories are written,she hopes to gain a better understanding of particle physicsitself. She is interested in studying quantum field theory vianonperturbative methods in supersymmetric theories. Often theonly method available in the framework of quantum fieldtheory is perturbation theory, which breaks down at strongcoupling. To get around this limitation, particle theorists utilizethe powerful tools of supersymmetry and duality.Supersymmetric models have an extra symmetry which oftenallows exact determination of some nonperturbative propertiesof field theories. The concept of duality is fundamental to thestructure of physical theories, relating two seemingly differentphysical theories in unexpected ways. Emily’s research hingeson the many insights that have come from studying the role ofduality in strongly coupled non-Abelian gauge theories. Shestudies, in particular, the many puzzling aspects of duality insupersymmetric quantum chromodynamics, a class of quantumfield theories that exhibit Seiberg duality. Emily enjoys cooking,making espresso, running, and watching movies.

Benefits to Society:The framework of quantum field theory encompasses themathematical structure of particle physics, condensed mattersystems, and the physics of the early universe, accuratelydescribing experiments in all contexts. Because it is such abroad and fundamental framework in modern physics, it isimportant that we better understand what it can and cannotteach us, and search for new ways to ask questions in physicswhose answers are not limited by the current framework.Already, progress toward new and more efficient ways ofthinking about quantum field theory has led to new insightsacross several disciplines in physics, from fluid dynamics togeneral relativity, and it is likely that continuing this line ofresearch will continue to have far-reaching and unexpectedconsequences across the whole field of physics.

Awards and Honors:Disney Scholars award, provided by Walt Disney Co. Foundation

DAVID NELLESUniversity of California, San DiegoJacobs School of EngineeringDegrees:M.S. in Materials Science and Engineering,University of California, San DiegoB.S. in Engineering Physics, University ofPittsburgh

Scholar Sponsor:Virginia Lynch Grady Endowment

About the Scholar:David is developing methods to measure the behavior of livingcells noninvasively. Stem cell therapies to replace damagedbrain or spinal tissue are an exciting prospect, but it is currentlyimpossible to measure the behavior of transplanted cellsnoninvasively. For any medical procedure, it is critical to trackboth the safety and efficacy of the treatment. David recentlydeveloped a noninvasive means of tracking cell behavior thatworks in a petri dish, and he is currently working to extend thistool to transplanted cells. David is a sculptor in various mediabut his favorites are plaster carving and torch-welded steelsculpture.

Benefits to Society:David is developing enabling technologies for stem cell andother cell-based transplantation therapies. The promise of stemcell therapy to replace damaged and diseased tissue will onlybe realized when the safety and efficacy of these approachescan be evaluated. With this goal in mind, he is developingengineered biomolecular systems (engineered proteins andpolymers) that will enable noninvasive tracking of stem cells inthe human body to aid both the development of stem celltherapies and also ensure the safety of stem cell therapies.

Awards and Honors:Recipient of an NSF Graduate Research Fellowship, a highly-competitive fellowship for graduate students in science andtechnology (2011-2014)Participant in an NSF-funded Research Experience forUndergraduate (REU) at Columbia University (2007)Participant in an NSF-funded Research Experience forUndergraduate (REU) at MIT (2008)Focht- Powell Graduate Research Fellowship from the UCSDJacobs School of Engineering (2009-2010)Member of the “Nifty Fifty” Sciencebridge outreach program.Paired with a local high school teacher at Santee High School todevelop and teach lessons that introduce students to conceptsin genomics (2010- 2012)

Publications and Posters:Rush, A.; Nelles, D.; Blum, A.; Barnhill, S.; Tatro, E.; Yeo, G.;Gianneschi, N.C. Intracellular mRNA Regulation with Self-Assembled Locked Nucleic Acid Polymer Nanoparticles. J. Am.Chem. Soc 2014, 136 (21), pp 7615–7618. This work describesthe development of DNA molecule modified with a polymercapable of entering live human cells and reducing expressionof a cancer-related gene.Nelles, D. A.; Fang, M. Y.; Aigner, S.; and Yeo, G. W. Applicationsof Cas9 as an RNA-programmed RNA-binding protein.Bioessays. 2015, 37, 732–739. This perspective describes thedevelopment of a system capable of noninvasive measure ofgene expression in live human cells using the CRISPR/Cas9genome engineering system.

Page 26: ARCS® Foundation, Inc., San Diego Chapter

24

JULIA NUSSBACHERUniversity of California, San DiegoSchool of Medicine, Sanford Consortiumfor Regenerative Medicine

Degrees:B.S. in Biochemistry, Brown University

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:Julia studies how RNA, the molecular intermediate betweenDNA and protein, is processed in the cell, specifically how it ismodified by proteins to acquire additional function or undergoalternative processing. She is particularly interested in the roleof RNA modification in neural development and neuro-degeneration. She uses high-throughput sequencing,genomics, bioinformatics, biochemistry, and cellular biologytechniques to understand how the modification of RNAs affecttheir function in a stem-cell based model of developingneurons. Her goal is to better understand how RNAmodification contributes to normal neural development and toidentify potential roles in disease and degeneration. Julia lovescooking with friends, reading fiction, and weightlifting.

Benefits to Society:RNA plays a significant role in several disease pathologiesincluding neural developmental disorders and neuro-degeneration. By elucidating the mechanisms through whichRNA methylation regulates protein binding to its targets andthereby modulates the fate of a significant portion of thetranscriptome, we can better understand both normal cellularprocesses as well as the mechanisms of disease pathology. Abetter understanding of the RNA-mediated pathology willenable us to identify new and better targets for therapeuticintervention.

Awards and Honors:NIH/NCI Cancer Training Grant Recipient 2012, 2013, UCSDSchool of MedicineGenentech Foundation Fellow 2011, UCSD School of MedicineHonors in Biochemistry, Brown UniversityAssociate Member ™• The Scientific Research Society, BrownUniversity

Publications and Posters:Nussbacher, J. K.; Batra, R.; Lagier-Tourenne, C.; Yeo, G. W.,RNA-binding proteins in neurodegeneration: Seq and you shallreceive. Trends in neurosciences 2015.

Axelsson, J.; Xu, D.; Kang, B. N.; Nussbacher, J. K.; Handel, T.M.; Ley, K.; Sriramarao, P.; Esko, J. D., Inactivation of heparansulfate 2-O-sulfotransferase accentuates neutrophil infiltrationduring acute inflammation in mice. Blood 2012, 120 (8), 1742-51.

Tomas Bos, Julia Nussbacher, Gene WYeo. Tethering of RNAbinding proteins to reveal molecular insights. "Genome-wideprobing of RNA processing", edited by Gene Yeo, Advances inExperimental Medicine and Biology, Springer publishing.

TIM O’CONNORUniversity of California, San DiegoJacobs School of Engineering,Department of NanoEngineering

Degrees:M.S. in NanoEngineering, University ofCalifornia, San Diego

M.S. & B.S. in Physics, Bowling Green State University

Scholar Sponsor:Reuben H. Fleet Foundation Fund

About the Scholar:Tim uses newly developed electronic materials to buildstretchable “plastic” electronics with the main goal of creatingflexible and stretchable solar cells. He also designs wearableelectronics for bio-medical applications. These wearableelectronic devices can be used as power sources, bio-sensors,and pressure sensors for new-age medical technologies.Stretchable and wearable electronic devices can be manu-factured using printing technologies, allowing them to be madeat low cost and in large volumes, to make energy and medicalmaterials and devices more cost effective in the future. Timenjoys gymnastics, running, hiking, guitar, surfing, and usingart in technology.

Benefits to Society:Tim’s research will contribute to the efforts for a clean energyfuture by developing cost effective, durable solar cells for grid-tied and off-grid applications. It also aims to develop techniquesfor producing low cost, wearable biomedical devices. Thisresearch will provide a fundamental understanding of themechanics of stretchable electronic devices and push the tech-nological frontiers of printed electronics by bridging the gapbetween laboratory fabrication and larger scale manufacturing.

Awards and Honors:National Defense Science and Engineering Graduate FellowshipBuilding Ohio’s Sustainable Energy Future ScholarshipGraduated with Cum Laude distinction (Bowling Green StateUniversity)James Robert and Gretchen Overman ScholarshipDean’s Honors List

Publications and Posters:O’Connor, T. F.; Zaretski A. V.; Savagatrup S.; Printz A. D.; WilkesC. D.; Diaz M. I.; Lipomi D. J. Ultra-flexible organic solar cellsfor powering wearable electronics. Sol. Energ. Mat. Sol. Cells.2015 (accepted).

O’Connor T. F.; Rajan K. M.; Printz A. D.; Lipomi D. J. Towardorganic electronics with properties inspired by biological tissue.J. Mater. Chem. B. 2015, 10.1039/C5TB00173K.

O’Connor T. F.; Zaretski A. V.; Shiravi B.; Savagatrup S.; Printz A.D.; Diaz M. I.; Lipomi D. J. Stretching and Conformal Bonding ofOrganic Solar Cells to Hemispherical Surfaces. Energy &Environ. Sci. 2014, 7, 370.

O’Connor T. F.; Panov M.; Mereshchenko A.; Tarnovsky A.; LorekR.; Perera D.; Diederich G.; Lambright S.; Imboden M.; ZamkovM. The Effect of the Charge-Separating Interface on ExcitonDynamics in Photocatalytic Colloidal Heteronanocrystals. ACSNano. 2012, 6, 8156.

Page 27: ARCS® Foundation, Inc., San Diego Chapter

MATT ONDECKUniversity of California, San DiegoSanford Consortium for RegenerativeMedicine

Degrees:M.S. in Materials Science andEngineering, University of California, San DiegoB.S. in Materials Science and Engineering & Bioengineering, Carnegie Mellon Univ.

Scholar Sponsor:Hervey Family Non-Endowment Fund

About the Scholar:Breast cancer fibrosis is a dynamic process that results inmatrix tissue stiffness increase. Mammary epithelial cellsdevelop into 3D hollow spheres called “acini” on soft tissuewhere the cells rearrange into a polarized spherical structure.Mammary cells respond to an increase in tissue stiffness andresemble a malignant state on stiffer tissue, lacking anypolarized acinar structure. This is akin to the stiff mammarytumors that one can detect with manual palpation. Current in-vitro techniques to simulate dynamic stiffening use staticPolyacrylamide hydrogels as cell scaffolds. However, thesescaffolds remain static and therefore are not very comparableto what is seen in the human body.To more fully simulate thefibrosis that occurs in breast cancer, Matt is using a stiffeningMethacrylated Hyaluronic Acid (MeHA) hydrogel that increasesin stiffness with UV light. This novel MeHA hydrogel allowsadherent mammary acini to see a healthy stiffness initially, thena diseased stiffness, which is more similar to what cells wouldsee during breast cancer progression. When he is not in thelab, Matt enjoys hiking, San Diego beaches, sailing, and sports.

Benefits to Society:Although Matt’s research is based largely around the mammarytumor environment, critical processes such as developmentand tumor formation are all based out of dynamically stiffeningtissues. Due to the complexities of developing a dynamicmodel, these systems are rarely simulated, which hindersresearchers’ ability to fully understand the mechanisms bywhich they evolve. The ability to mimic a variety of dynamicbiological substrates will allow researchers to investigate amyriad of cellular states, such as a myocardial infarction, wherethe resulting scar tissue is much stiffer than the surroundingheart tissue. The novelty and innovativeness of this projectposes to contribute to the overall wealth of knowledge in thescientific community.

Awards and Honors:NSF GRFP Fellowship 2013ASCB 2013-2014 Poster Presentee

Publications and Posters:Ondeck, M.G., Viswanathan, P., Chirasatitsin, S., Nghamkham, K., Reilly,G.C., Engler, A.J., and Battaglia, G. 3D Surface Topology Guides StemCell Adhesion and Differentiation. Biomaterials. 2015, 52:140-147.

Hribar, K.C., Choi, Y.S., Ondeck, M., Engler, A.J., and Chen, S. DigitalPlasmonic Patterning of Hydrogels. Adv Funct Mat. 2014, 24(31) 4922-26.

Ondeck, M.G., Engler, A.J., Dynamic Materials Mimic Deveolpmental andDiesease Changes in Tissues. IN Bio-inspired Materials for BiomedicalEngineering. Brennan, A.B, Kirschner, C.M. Wiley-Soceity forBiomaterials, 2014, 25-45.

A.Habib, M.Ondeck, K.Miller, R.Swaminathan, M.McHenry; Novel solder-magnetic particle composites, their reflow using AC magnetic fields;IEEE Journal; Trans on Magnetics;Vol.46,No.6, 2187-90; 6/2010.

SETH PARKERUniversity of California, San DiegoJacobs School of EngineeringDegrees:M.S. in Bioengineering, University ofCalifornia, San DiegoB.S. in Chemical and BiologicalEngineering, University of Colorado at Boulder

Scholar Sponsors:Drs. Mara and Larry Ybarrondo/ARCS Foundation

About the Scholar:Seth studies how mutations in specific genes affect cancer cellmetabolism. Through the use of stable-isotope tracing andmass spectrometry, Seth can visualize metabolic pathwayactivity and understand how these mutations influencepathway flux. Seth’s goal is to identify metabolic deficienciesand develop optimal strategies to treat tumors bearing thesemutations. Seth also develops novel stable-isotope tracingmethods to characterize the activity of metabolic pathways notpossible using current methods. Outside of the lab, Seth enjoysoutdoor activities such as camping, surfing, and rock climbingand is an avid home brewer.

Benefits to Society:Cancer is an inherently genetic disease caused by theaccumulation of mutations in genes controlling various cellularprocesses. With the decreasing cost of next-generation DNAsequencing, a greater number of cancer patients can have theirtumors genotyped and therapies can be tailored to individualtumors. In order for this vision to become reality, a molecularunderstanding of how specific mutations affect tumor meta-bolism and growth is required to design effective therapeuticstrategies that kill tumors of a particular genetic profile.

Awards and Honors:Siebel Scholar, Class of 2016

NIH/NCI Ruth L. Kirschstein National Research Service Award(F31), 2015-2017

NIH/NIBIB Ruth L. Kirschstein National Research Service Award(T32), 2012-2014

HHMI Teaching Innovation Program (TIPS) grant, 2014

Mr. and Mrs. David and Margaret Grohne Scholarship, 2007-2011

Publications and Posters:Parker, S. J. and Metallo, C.M. Metabolic consequences ofoncogenic IDH mutations. Pharmacology & Therapeutics. 2015,152, 54-62.

Lewis, C. A.; Parker, S. J. et al. Tracing compartmentalizedNADPH metabolism in the cytosol and mitochondria ofmammalian cells. Mol. Cell. 2014, 55(2), 253-263.

Grassian, A. R.; Parker, S. J. et al. IDH1 mutations alter citricacid cycle metabolism and increase dependence on oxidativemitochondrial metabolism. Cancer Res. 2014, 74(12), 3317-3331.

Commisso, C.; Davidson, S. M.; Soydaner-Azeloglu, R. G.;Parker, S. J.; et al. Macropinocytosis of protein is an amino acidsupply route in Ras-transformed cells. Nature. 2013, 497(7451),633-637.

25

Page 28: ARCS® Foundation, Inc., San Diego Chapter

26

ERIK PAULSONSan Diego State UniversityDepartment of Chemistry andBiochemistry

Degrees:Single Subject Teaching Credential,University of California, Riverside

B.S. in Chemistry, University of California,Riverside

Scholar Sponsor:Kathryn Crippen Hattox Fund

About the Scholar:The Grotjahn group makes catalysts that make reactions faster usingan approach that mimics Nature’s catalysts: enzymes. Enzymes oftenuse the activity of a metal like iron or copper to assist in the buildingof molecules, but the metal can be tailored using organic molecules asshrubbery (a protein, for example). In this whole system, there is asynergistic interplay between the two that can allow these enzymes toefficiently and selectively create the molecules of life. His groupdesigns catalysts in which they attach organic molecules to the metalthat not only directly tailor the metal’s activity, but also play an activerole in the reaction itself! They call these bifunctional catalysts. In Erik’sparticular case, the transformation achieved with his catalysts is themigration of a double bond down a chain, a reaction which can requirea base to shuttle and shift a hydrogen atom around. By attaching adangling organic base directly to the metal as opposed to it floatingaround free in solution, he can achieve rate increases on themagnitude of 300 to 10000! In his spare time, Erik loves traveling,hiking, and watching San Diego Chargers football.

Benefits to Society:Erik’s group has tailored their catalysts to be incredibly selective toproduce (E)-alkenes. A direct potential area of application to cross overinto the commercial sector is with flavors and fragrances. They can usetheir catalysts to take essential oils like clove oil (eugenol) and shiftthe double bond to give essentially exclusively (E)-isoeugenol, whichhas a scent like nutmeg, without forming the harsh-smelling (Z)-isoeugenol. There are thousands of syntheses of natural products orderivatives in which a double bond is functionalized as part of theprocess, and their catalysts provide a mild synthetic transformation ofthis double bond, which can lead to more efficient routes ofsynthesizing pharmaceutical or other commercial products.

Awards and Honors:Organic Reactions Catalysis Society (ORCS) Travel Award(March 2014)Two-time Teacher of the Month, John Burroughs High School,Burbank, California (January and November 2007)

Publications and Posters:Larsen, C. R., Paulson, E. R., Erdogan, G., Grotjahn, D. B. AFacile, Convenient, and Green Route to (E)-PropenylbenzeneFlavors and Fragrances by Alkene Isomerization. Synlett 2015,Ahead of Print. (Authors contributed equally)Grotjahn, D.B., Larsen, C.R., Erdogan, G., Paulson, E.R. Terminalalkene monoisomerization catalysts and methods. U.S. Pat.Appl. Publ., US 20150231621 A1 20150820, January 9, 2015.Paulson, E.R., Larsen, C.R., Erdogan, G. Grotjahn, D.B. Abstractsof Papers, 248th ACS National Meeting and Exposition, SanFrancisco, California, August 10th-14th, 2014; AmericanChemical Society: Washington, DC, 2014; ORGN-683.Paulson,E.R., Grotjahn, D.B. Book of Abstracts, 25th BiennialOrganic Reactions Catalysis Society Conference, Tuscon,Arizona, March 2nd-6th, 2014.

GABE PRATTUniversity of California, San DiegoBioinformatics and Systems BiologyGraduate ProgramDegrees:B.S. Computer Science, University ofWashington, Seattle

Scholar Sponsor:ARCS Foundation

About the Scholar:Gabe is interested in using computers to understand and helpelucidate major unanswered questions in biology. Specifically,he develops and applies techniques from the data science fieldto understand what causes Amyotrophic Lateral Sclerosis(ALS), also known as Lou Gehrig’s disease. ALS may be causedby a dysfunction of RNA processing so he works to understandthe differences between RNA in patents and cells with ALS andthose unaffected by the disease. Additionally to better under-stand general RNA processing, he characterizes what proteinsare associated with RNA and how they affect RNA in regularcells. Gabe is an avid swimmer and enjoys spending time inthe outdoors.

Benefits to Society:Gabe’s research advances are twofold. First by understandingthe root causes of ALS, we can progress towards finding a curefor this devastating disease. Second, his general RNAcharacterization project is a science accelerator. He is makingthe data from the project available to anyone pre-publication,so scientists with specific questions will be able to askquestions and answer questions that he may not have thoughtof and they, previously, may not have had the capability toanswer.

Awards and Honors:National Science Foundation Graduate Research FellowshipProgram

JASSO Fellowship

Publications and Posters:Lee, S. R.; Pratt, G. A.; Martinez, F. J.; Yeo, G. W.; Lykke-Andersen, J. Mol. Cell 2015, 59 (3), 413–425.

Singh, G.; Pratt, G.; Yeo, G. W.; Moore, M. J. Annu. Rev.Biochem. 2013, 84 (1), 150317182619002

Lovci, M. T.; Ghanem, D.; Marr, H.; Arnold, J.; Gee, S.; Parra, M.;Liang, T. Y.; Stark, T. J.; Gehman, L. T.; Hoon, S.; Massirer, K. B.;Pratt, G. a; Black, D. L.; Gray, J. W.; Conboy, J. G.; Yeo, G. W.Nat. Struct. Mol. Biol. 2013, 20 (12), 1434–1442.

Paige, S. L.; Thomas, S.; Stoick-Cooper, C. L.; Wang, H.; Maves,L.; Sandstrom, R.; Pabon, L.; Reinecke, H.; Pratt, G.; Keller, G.;Moon, R. T.; Stamatoyannopoulos, J.; Murry, C. E. Cell 2012, 151(1), 221–232.

Page 29: ARCS® Foundation, Inc., San Diego Chapter

27

STEPHEN EDWARD RICESan Diego State UniversityCollege of Sciences

Degrees:M.S. in Biology, Old Dominion University

B.A. in Biology, University of NorthCarolina, Asheville

Scholar Sponsor:ARCS Foundation

About the Scholar:Stephen uses molecular genetic tools paired with mathematicalmodeling to understand the evolutionary ecology of reptiles in SouthernCalifornia and to assess the viability of these populations in the future.He works on the mainland with Southern Pacific rattlesnakes and on theChannel Islands with the island night lizard. These species have hadlittle-to-no previous genetic work conducted and very little is known oftheir demography, sensitivity to climate change, or the extinction risksposed by synergistic threats. His objectives are to understand patternsof genetic diversity within these species and use these data to assessextinction risk and identify management strategies.

Benefits to Society:Stephen’s research will benefit society by increasing educationalopportunities for undergraduates and volunteers; allow for fiscallyresponsible planning and conservation efforts; provide insight intocontemporary processes; and allow the projection of future trends forproactive management. The main benefit that his research will have is amethodological basis of assessing current patterns of genetic diversityand population subdivision within species that provide ecologicalservices, which are generally lacking from economic forecasts but willbecome increasingly vital under global climate change.

Awards and Honors:Laurel ScholarAsheville Civitan Club ScholarWestern North Carolina Leadership Scholar

Publications and Posters:Rose, R.K.; Rice, S.E. 2013. Patterns of Transience, Sex Bias,and Body Mass in Open-habitat Rodent Populations. AmericanSociety of Mammalogists, Philadelphia, PA. June 14-18, 2013.

Rice, S.E.; Anderson, K.A.; Regan, H.M.; Syphard, A.; Franklin,J.; Bonebrake, T.; Winchell, C. Threat Assessment and Dispersalof the Big-eared Woodrat (Neotoma macrotis). University ofCalifornia Riverside Gradfest Symposium, Riverside, CA. March9, 2013.

Schuett, G.W.; Hoss, S.K.; Rice, S.E. Crotalus atrox (Westerndiamond-backed rattlesnake), Crotalus ruber (Red-diamondrattlesnake). Loss of rattle and style/matrix. HerpetologicalReview, 2012, 43(2), 341-342.

DUSTIN RICHMONDUniversity of California, San DiegoJacobs School of Engineering, ComputerScience & Engineering DepartmentDegrees:B.S. in Computer Engineering, Universityof WashingtonB.S. in Electrical Engineering, University of Washington

Scholar Sponsor:Reuben H. Fleet Foundation Fund/ARCS Foundation

About the Scholar:Application web servers spend significant time serving simplerequests with large overhead. Unfortunately, these simplerequests waste significant power and cycles. At the scale of asingle data center, this represents an enormous cost.Fortunately, the workload for these servers is well known andsolutions can be applied to many thousands of servers. Dustinis working on techniques to offload some of the simplecomputations into the networking hardware to improve theefficiency of web servers in large data centers.

Benefits to Society:Dustin’s work will reduce the power consumed by data centers,

which are the backbone of the web as it exists today. His work

will also improve the performance of some web server

applications. Finally, this work will also be open source so the

products of his research will be available for extension by other

academic researchers and use in industry.

Awards and Honors:Charles Lee Powell Fellowship

National Science Foundation Graduate Research Fellowship

Eta Kappa Nu Honor Society President (Iota Upsilon chapter)

Publications and Posters:Jacobsen, M.; Richmond, D.; Hogains, M.; Kastner, R. RIFFA 2.1:A Reusable Integration Framework for FPGA Accelerators, InACM Transactions on Reconfigurable Technology and Systems.Gautier, Q.; Shearer, A., Matai, J.; Richmond, D.; Meng, P.;Kastner, R. Real-time 3D Reconstruction for FPGAs: A CaseStudy for Evaluating the Performance, Area, andProgrammability Trade-offs of the Altera OpenCL SDK, InProceedings of The International Conference on FieldProgrammable Technology 2014. Richmond, D.; Kastner, R.; Irturk, A.; McGarry, J. “A FPGAdesign for high speed feature extraction from a compressedmeasurement stream” In Proceedings of The InternationalConference on Field Programmable Logic 2013.Brossard, E.; Richmond, D.; Green, J.; Ebeling, C.; Ruzzo, L.;Olson, C.; Hauck, S. "A Model for Programming Data-IntensiveApplications on FPGAs: A Genomics Case Study," InProceedings of Symposium on Application Specific HighPerformance Accelerators 2012.

Page 30: ARCS® Foundation, Inc., San Diego Chapter

28

KELLY ROSSSan Diego State UniversityCollege of Sciences

Degrees:B.S. in Microbiology, Pennsylvania StateUniversity

Scholar Sponsor:French and Masserini Funds

About the Scholar:Kelly is researching the function of SoxB transcription factorgenes in planarian neurogenesis. Planarians are non-parasiticflatworms with a molecularly complex central nervous systemthat completely regenerates following amputation or injuryfrom a population of adult pluripotent stem cells. In particular,one SoxB gene (Sox1-like) causes seizure-like behaviors inplanarians following light exposure as well as smallerregenerated brains. She aims to uncover genetic targets ofSox1-like by performing RNA sequencing on control and Sox1-like deficient planarians. This data set has already revealed adownregulation of genes necessary for neural function. In herspare time, Kelly enjoys cooking, reading, and spending timeoutside with her family and dog.

Benefits to Society:In mice, loss of the gene Sox1 leads to epileptic seizures, andhuman genome-wide association studies have implicated Sox1mutations in epileptic disorders. However, the genes regulatedby Sox1 in the brain remain largely unknown. Thus, uncoveringthe genetic targets of Sox1 would provide crucial insights intohuman disease. Kelly’s current goals are to determine whichgenes are directly affected by Sox1-like malfunction inplanarians to further elucidate the molecular mechanismsunderlying seizures in humans and to establish planarians as amodel for seizure disorders.

Awards and Honors:Anita Roberts Memorial Fund Travel Fellowship

European Molecular Biology Organization Travel Fellowship

SDSU Student Research Symposium Provost’s Award

SDSU Instructionally Related Activities Travel Grant

Publications and Posters:Ross, K.G.; Omuro, K. C.; Taylor, M. R.; Munday, R. K.; Hubert A.;King R. S.; Zayas, R. M. Novel monoclonal antibodies to studytissue regeneration in planarians. BMC Dev. Biol. 2015, 15(1), 2.

Forsthoefel, D. J.*; Ross, K. G.*; Newmark, P. A.; Zayas, R. M.Fixation, processing, and immunofluorescent labeling of wholemount planarians. In Methods for Planarian Research: Methodsin Molecular Biology, (In press). *These authors contributed equally.

Hubert, A.; Henderson, J. M.; Cowles, M. W.; Ross, K. G.; Hagen,M.; Anderson, C.; Szeterlak, C. J.; Zayas, R. M. A functionalgenomics screen identifies an Importin-alpha homolog as aregulator of stem cell function and tissue patterning duringplanarian regeneration. BMC Genomics, (In press).

Hubert, A.; Henderson, J. M.; Ross, K. G.; Cowles, M. W.; Zayas,R. M. Epigenetic regulation of planarian stem cells by theSET1/MLL family of histone methyltransferases. Epigenetics.2012, 8(1), 79-91.

KEVIN ROSSUniversity of California, San DiegoBiomedical Sciences Graduate ProgramDegrees:B.S. in Molecular and CellularBiology/Psychology, University of Illinois,Urbana-ChampaignM.S. in Physics, University of California, San Diego B.S. in Chemistry, University of Arizona

Scholar Sponsor:ARCS Foundation

About the Scholar:Kevin’s research is focused on a unique regulatory role fornuclear export factor1 (Nxf1), whose main function is torecognize mature mRNA transcripts and facilitate their transportfrom the nucleus to the cytoplasm of a cell. An additionalfunction of Nxf1 is the suppression of genetic mutations causedby retroviruses in mice, in a manner that suggests it occurs priorto the recognition of a mature mRNA. He is studying the specificmechanism of this suppression, and the role of variation in Nxf1that determines its interaction with other factors involved inmRNA processing and maturation. In his free time, he serves asa representative on the UCSD Graduate Student Association, andparticipates in his own program’s graduate council, which worksto enrich the lives of students outside of the lab. He also is anavid racquetball player.

Benefits to Society:Understanding the functional consequences of commongenetic variation in the context of disease risk and severity is asubject of great importance to society. Nxf1 sits at the centerof a gene regulatory network, and common, non-pathogenicvariation in Nxf1 has a significant impact on the outcome ofpotential disease-causing mutations in other genes in mice. Adetailed understanding of the role of Nxf1 in mRNA maturationand processing will provide new insights into complex geneticsystems that underlie disease.

Awards and Honors:NIH Training Program in Basic and Clinical GeneticsBest Poster Award, Mouse Molecular Genetics Conference,Genetics Society of AmericaEdmund J. James Scholar, University of Illinois

Publications and Posters:Zhang, S.; Ross, K. D.; Seidner, G. A.; Gorman, M. R.; Poon, T. H.; Wang, X.; Keithley,E. M.; Lee, P. N.; Martindale, M. Q.; Joiner, W. J.; Hamilton, B. A., Nmf9 Encodes aHighly Conserved Protein Important to Neurological Function in Mice and Flies. PLoSgenetics 2015, 11 (7), e1005344.

Concepcion, D.; Ross, K. D.; Hutt, K. R.; Yeo, G. W.; Hamilton, B. A., Nxf1 NaturalVariant E610G Is a Semi-dominant Suppressor of IAP-Induced RNA ProcessingDefects. PLoS genetics 2015, 11 (4).

Uricchio, L. H.; Chong, J. X.; Ross, K. D.; Ober, C.; Nicolae, D. L., Accurate Imputationof Rare and Common Variants in a Founder Population From a Small Number ofSequenced Individuals. Genetic Epidemiology 2012, 36 (4), 312-319.

Torgerson, D. G.; Ampleford, E. J.; Chiu, G. Y.; Gauderman, W. J.; Gignoux, C. R.;Graves, P. E.; Himes, B. E.; Levin, A. M.; Mathias, R. A.; Hancock, D. B.; Baurley, J. W.;Eng, C.; Stern, D. A.; Celedon, J. C.; Rafaels, N.; Capurso, D.; Conti, D. V.; Roth, L. A.;Soto-Quiros, M.; Togias, A.; Li, X. N.; Myers, R. A.; Romieu, I.; Van Den Berg, D. J.; Hu,D. L.; Hansel, N. N.; Hernandez, R. D.; Israel, E.; Salam, M. T.; Galanter, J.; Avila, P. C.;Avila, L.; Rodriquez-Santana, J. R.; Chapela, R.; Rodriguez-Cintron, W.; Diette, G. B.;Adkinson, N. F.; Abel, R. A.; Ross, K. D.; Shi, M.; Faruque, M. U.; Dunston, G. M.;Watson, H. R.; Mantese, V. J.; Ezurum, S. C.; Liang, L. M.; Ruczinski, I.; Ford, J. G.;Huntsman, S.; Chung, K. F.; Vora, H.; Li, X.; Calhoun, W. J.; Castro, M.; Sienra-Monge,J. J.; del Rio-Navarro, B.; Deichmann, K. A.; Heinzmann, A.; Wenzel, S. E.; Busse, W.W.; Gern, J. E.; Lemanske, R. F.; Beaty, T. H.; Bleecker, E. R.; Raby, B. A.; Meyers, D. A.;London, S. J.; Gilliland, F. D.; Burchard, E. G.; Martinez, F. D.; Weiss, S. T.; Williams, L.K.; Barnes, K. C.; Ober, C.; Nicolae, D. L.; Asthma, M. C. C.; Study, C. H.; Study, H.;Admixture, S. G. E.; Asthma, S. A. A.; Network, C.; CAMP; SAPPHIRE; Study, G.,Meta-analysis of genome-wide association studies of asthma in ethnically diverseNorth American populations. Nature genetics 2011, 43 (9), 887-U103..

Page 31: ARCS® Foundation, Inc., San Diego Chapter

JULIA ROSSISan Diego State UniversityCollege of Sciences, Computational ScienceResearch CenterDegrees:M.S. in Physics, San Diego StateUniversityB.A. in Physics, University of San DiegoB.A. in Biology, University of San Diego

Scholar Sponsor:Cymer, Inc.

About the Scholar:Julia is using computational methods to research polaritonBose-Einstein condensates (BECs) in semiconductormicrocavities. Unlike atomic BECs that need operatingtemperatures close to absolute zero (of the order of nanoKelvin), polariton BECs exist at much higher temperatures.Polariton BECs, consisting of short-lived exciton-photonquasiparticles, are an excellent candidate for solid-stateapplications in quantum computing, quantum clocks, and otherhigh-precision devices. Julia’s objective is to utilize asynergistic approach by bringing together mathematics,physics, and state-of-the-art computational methods towardunderstanding and driving cutting-edge technologicaldevelopments. Julia enjoys surfing, snowboarding, andpainting in her spare time.

Benefits to Society:Polariton condensates exhibit remarkable features such assuperfluidity, allowing for a broad range of applicationsincluding spin switches, light-emitting diodes, quantumcomputing, quantum clocks, and lasers operating at muchhigher efficiency than traditional lasers. One of the mostexciting technological applications of Bose-Einsteincondensates is perhaps in quantum computing, whereby a newcomputational paradigm, based on quantum information, couldenable ultra-fast computers to perform a multitude ofsimultaneous operations by virtue of laws of quantummechanics.

Awards and Honors:Wilmia Tyler Trott Memorial Scholarship

State University Grant

Summer Undergraduate Research Experience

Publications and Posters:Rossi, J.M., Atomic Factorization of Molecular Interactions.M.S. Thesis, San Diego State University, San Diego, CA.

BEN RUBINUniversity of California, San DiegoGraduate Biology ProgramDegrees:B.A. in molecular biology andbiochemistry, and economics atMiddlebury College

Scholar Sponsor:ARCS Foundation

About the Scholar:Cyanobacteria are major contributors to the Earth’s oxygen-richatmosphere and they make up a substantial portion of its greenlife. In addition to being used to understand fundamentalprocesses such as the production of organic matter from light,cyanobacteria are currently being developed as productionplatforms for renewable fuels, chemicals and pharmaceuticals;however, the understanding and use of cyanobacteria as a bio-production platform has been hampered by a lack of under-standing of the complete set of genes and pathways important tothe organisms’ survival. Ben has created a collection of 250,000cyanobacteria mutants to identify the complete set of essentialgenetic elements in this organism. Ben is a member of theUCSD Surf Team, a runner, a biker, an addict of news podcasts,an avid cook, a reader, and a tender of orchids.

Benefits to Society:This research provides the first complete picture of the geneticcogs essential for the survival of an organism that uses light forenergy. As such, it will aid our understanding of thefundamental process that drives the plants, algae, andphotosynthetic bacteria that dominate our ecosystem, andpotentially provide the framework necessary to syntheticallygenerate these organisms. More concretely, this work producesgeneral data and specific metabolic conclusions that willilluminate the basic biology of cyanobacteria and facilitate itsdevelopment as a bioproduction platform.

Awards and Honors:Goeddel Graduate Scholar Award, University of California SanDiego June 2015The Biology Program Award for Teaching Excellency, University ofCalifornia San Diego Sept 20143rd place in Grand Slam, University of California San Diego. Auniversity-wide graduate student speaking competition. April 2014Honors in Molecular Biology and Biochemistry, MiddleburyCollege May 2011College Scholar, Middlebury College Fall 2009

Publications and Posters:Diamond, S.; Jun, D.; Rubin, B. E.; and Golden, S. S.; Circadiancontrol of carbon metabolism in Synechococcus elongatusPCC7942. Proc. Natl. Acad. Sci. 2015, 112, 1916-1925.

Rubin BE et al. “The Minimal Genome of a PhotosyntheticMicroorganism.” International Symposium on PhototrophicProkaryotes: August 2-6; Tübingen, Germany.

Diamond S, Rubin BE, Shultzaberger R, and Golden S“Circadian Output in S. elongatus Activates MetabolicFunctions Important for Diurnal Viability.” Food and Fuels forthe Twenty First Century; 2015 March 12-13; La Jolla CA.

Diamond S, Rubin BE, Jun D, and Golden SS. Integration ofCircadian External Signals in Metabolic Control inSynechococcus elongatus PCC 7942. 11th Workshop onCyanobacteria; 2013 Aug 7-10; St. Louis, MO.

29

Page 32: ARCS® Foundation, Inc., San Diego Chapter

30

SUCHOL SAVAGATRUPUniversity of California, San DiegoJacobs School of EngineeringDegrees:B.S. in Chemical Engineering, Universityof California, Berkeley

Scholar Sponsor:Lambert Family Foundation for Education at Union Bank

About the Scholar:Suchol studies the mechanical properties and degradationbehaviors of semiconducting polymers. Semiconductingpolymers are ubiquitous to organic electronics such as organicsolar cells, light-emitting diodes, and sensors. Understanding theinterplay between mechanical resilience and high-performancesemiconducting properties will enable the engineering ofefficient electronic devices that can withstand extrememechanical deformation, for example, in ultra-low-cost solarpanels and wearable applications. When not working in the lab,Suchol enjoys cooking, following sports, and beer tasting.

Benefits to Society:Mechanically robust semiconducting polymers have numerousapplications for our future energy needs. They could potentiallyallow for roll-to-roll printing of organic solar panels that areportable and extremely lightweight, which will significantlyreduce the cost of manufacturing, installing, and repairing solarpanels on a massive scale. Additionally, this research onstretchable semiconductors directly impacts the healthcareindustry because of their applications in prosthetic sensors andconformable devices for monitoring electrical, chemical, andmechanical signals inside and outside the human body.

Awards and Honors:National Science Foundation Graduate Research Fellowship

Magna Cum Laude Graduate, UC Berkeley

College of Chemistry Dean’s Honor List, UC Berkeley

Melvin J. Heger-Horst Fellowship, UC Berkeley

Publications and Posters:Savagatrup, S.; Printz, A. D.; O’Connor, T. F.; Zaretski, A. V.;Rodriquez, D.; Sawyer, E. J.; Rajan, K. M.; Acosta, R. I.; Root, S.E.; Lipomi, D. J. Mechanical Degradation and Stability ofOrganic Solar Cells: Molecular and MicrostructuralDeterminants. Energy Environ. Sci. 2014. DOI:10.1039/C4EE02657H.

Savagatrup, S.; Printz, A. D.; O’Connor, T. F.; Zaretski, A. V.;Lipomi, D. J. Molecularly Stretchable Electronics. Chem. Mater.2014, 26, 3028.

Savagatrup, S.; Printz, A. D.; Rodriquez, D.; Lipomi, D. J. Best ofBoth Worlds: Conjugated Polymers Exhibiting GoodPhotovoltaic Behavior and High Tensile Elasticity.Macromolecules 2014, 47, 1981.

Savagatrup, S.; Makaram, A. S.; Burke, D. J.; Lipomi, D. J.Mechanical Properties of Conjugated Polymers and Polymer-Fullerene Composites as a Function of Molecular Structure.Adv. Funct. Mater. 2014, 24, 1169.

ANTHONY SHAOUniversity of San DiegoShiley-Marcos School of EngineeringDegrees:B.S./B.A. Electrical Engineering (InProgress)B.A. Finance (In Progress)

Scholar Sponsors:WD-40 Company/ARCS Foundation

About the Scholar:Anthony’s research set out to find the most apt way of teachingproblem solving to freshman engineers. He researched varioustechniques of problem solving methods, introspection, barriersto problem solving, and retention, and then created a lecturebased on these materials. He then gave the lecture to severalclasses of freshman engineers and analyzed their knowledgepre and post lecture. He found that students became morefamiliar with problem solving methods after the lecture andthat the students felt more prepared and comfortable with thenew problem solving methods. Anthony enjoys playingbasketball, football, running, and various other sports. He alsosings in his free time, and loves to spend time with his familyand cat.

Benefits to Society:This research, albeit somewhat simple, adds to the ongoingdiscussion of “how to effectively teach.” The goal of thisresearch was to find a more apt way of teaching problemsolving. Since teaching is the fundamental base of alleducation, Anthony believes that creating a streamlined,effective, and collaborative system is the key to aiding theteaching world. This research adds to the world of sciencethrough its strengthening of the learning process, a crucialjunction in all of academia.

Awards and Honors:First Honors – Given to students with at least a 3.65 GPA

Beta Gamma Sigma Member – Honors Business Society

Honors Program at the University of San Diego

Publications and Posters:Problem Solving Methods – Created a poster and a paperregarding the processes and analysis of his research. Theposter was created to present at the AAAS Conference in SanFrancisco and at the University of San Diego. The paper, thoughstill in its editing process, details their methodology, findings,and analysis.

HP Intern Poster – This poster was created at an internship thispast summer with Hewlett-Packard. The poster was thenpresented to an open audience, detailing the steps he took tosave the company $2.4 million USD. The poster also detailedthe processes of printed circuit board design, cost analysis, andprocurement.

Page 33: ARCS® Foundation, Inc., San Diego Chapter

31

COLETTE SMIRNIOTISSan Diego State UniversityComputational Science Research Center,College of SciencesDegrees:M.S. in Statistics (Biostatistics), San DiegoState UniversityB.A. in Math and Economics,Washington University in St. Louis

Scholar Sponsor:ARCS Foundation

About the Scholar:Scientists use mathematical models to describe the weather,the oceans, and the climate. For example, consider themultiple hurricane paths weather forecasts show on the newswhen a hurricane is forming and approaching land. Colette’smain research is in the field of data assimilation, which is theprocess of combining real observations with the output fromthe models to update and improve forecasts. Her aim is toimprove existing algorithms, resulting in more accuratepredictions. Additionally, she is working on a project tocreate improved predictions of snowfall in the RockyMountains, using statistical methods to combine multiple datasets. When not at her computer, Colette enjoys swimming,running, hiking, and camping.

Benefits to Society:Weather and climate models are used to forecast everythingfrom hurricane trajectories to snowfall to sea level rise—all ofwhich can have significant impacts on society. Improvementsto existing data assimilation algorithms will improvepredictions. Better predictions for hurricane trajectories, forexample, would allow for better preparedness by communitiesin its path. More accurate snowfall estimates improve waterresource management, as snowfall is a major water source formuch of the Western United States.

Awards and Honors:Academic Excellence in Biostatistics, San Diego StateUniversity, 2013

Publications and Posters:Smirniotis, C.; Bailey, B. Comparison of Ensemble Filters forData Assimilation. Presented at the STATMOS/NCAR InvitedPoster Presentations at the Joint Statistical Meetings, Seattle,WA, August 8-13, 2015.

Smirniotis, C.; Bailey, B. Visualization of Data AssimilationMethods. Presented at the STATMOS/NCAR Invited PosterPresentations at the Joint Statistical Meetings, Seattle, WA,August 2-7, 2014.

WINSTON STAUFFERSan Diego State University, UC San DiegoSan Diego State University Heart Institute,Biology DepartmentDegrees:B.S. in Biology, UC Santa Cruz

Scholar Sponsor:ARCS Foundation

About the Scholar:Winston is interested in how the heart responds to stresses thatmimic what happens during a heart attack or congestive heartfailure on a cellular level. This includes how ischemic stress orlack of blood flow interferes with how heart muscle cells createand fold new proteins. If these processes are disrupted, thebuildup of misfolded proteins can become toxic and can lead tocell and tissue death. A set of genes designed to aid proteinfolding can be activated to prevent this from happening. Hisresearch focuses on identifying and manipulating these genes tolook for possible therapeutic targets beneficial to those withheart disease. In his spare time, Winston likes to read history,play trivia games and ultimate Frisbee, and dogs.

Benefits to Society:If a way can be found to enhance this gene program, called theUnfolded Protein Response, this could lead to a variety of newtreatments that prevent tissue death during and after a heartattack. This may preserve heart function and prevent cardiacremodeling that leads to heart failure. In the case of cardiacstem cells we may even be able to re-grow and repair damagedhearts without the need for surgery or transplants.

Awards and Honors:Rees-Stealy Research Foundation Fellow (2014 and 2015).

Publications and Posters:Stauffer, W.T., Bailey, B., Arrieta, A., Doroudgar, S., Glembotski,C.C. MANF is an ER Stress-inducible Protein with Novel Rolesas a Regulator of Cardiac Myocyte Growth. AHA ScientificSessions, Chicago, IL, November 15-19, 2014; American HeartAssociation. Oral Presentation.

Stauffer, W.T., Doroudgar, S., Stephens, H.N., Glembotski, C.C.The Adaptive ER Stress Response has a Critical Role inPromoting Proliferation and Viability in Cardiac ProgenitorCells. SDSU Graduate Student Seminar, San Diego, CA, April,2015. San Diego State University. Poster and oral presentations.

Stauffer, W.T., Doroudgar, S., Stephens, H.N., Bailey, B.,Glembotski, C.C. ATF6 and the Adaptive ER Stress ResponsePromotes Proliferation and Viability of Mouse CardiacProgenitor Cells. AHA Scientific Sessions, Orlando, FL,November 7-11, 2015; American Heart Association. PosterPresentation.

Page 34: ARCS® Foundation, Inc., San Diego Chapter

MIKE TAITUniversity of California, San DiegoDivision of Physical Sciences

Degrees:C.Phil. In Mathematics, University ofCalifornia, San Diego

M.S. In Mathematics, University of Delaware

B.S. In Mathematics and Economics, University of Delaware

Scholar Sponsor:Donald C. and Elizabeth M. Dickinson Foundation

About the Scholar:Mike is researching a number of problems in Graph Theory.Given an object’s set of specific properties, how large orsmall can it possibly be? For example, in an office one wantsall of the workers to be able to attend all their scheduledmeetings. What is the fewest number of time slots thecompany needs to get all of its meetings accomplished?Another example is determining how few numbers a creditcard can have to avoid transcription errors. Mike enjoysexercising, reading, and cooking.

Benefits to Society:Graph theory has many applications in the real world, fromscheduling, to route-planning, to modeling social andinformation networks, to understanding atomic structure. Inaddition, his area of research has applications to other areas ofmathematics, and one can use this theory to solve problems infields seemingly unrelated to it. Furthermore, the applicationsare interdisciplinary. His research area builds cryptography andelectrical engineering.

Awards and Honors:David A. Sharp Academic Excellence Award for Men'sTrack/Cross-Country

Clarks Award: Presented only when a senior majoring inmathematics has unusual ability in the area

Stephen J. Wolfe Memorial Scholarship: Awarded to a studentwho has demonstrated both love and talent for the subject

ESPN the Magazine Academic All-American Nominee

Publications and Posters:Cioaba, S.M.; Tait, M.; More counterexamples to the Alon-Saks-Seymour Conjecture and the Rank-Coloring Conjecture.Electronic J. Comb. 2011, P26, 1—9.

Cioaba, S.M.; Tait, M.; Variations on a theme of Graham andPollak. Disc. Math. 2013, 313-5, 665—676.

Tait, M.; Timmons, C.; Sidon sets and graphs without 4-cycles.J. Comb. 2014, 5-2, 155—165.

JOHN TAT The Scripps Research InstituteKellogg School of Science and Technology

Degrees:B.A. in History, University of California,San DiegoB.S. in Physiology and Neuroscience,University of California, San Diego

Scholar Sponsor:Hervey Family Non-Endowment Fund

About the Scholar:Given the diverse nature of cancer, John believes that cancerresearchers need to approach these diseases from multipleperspectives, so that the therapies they create will cure boththe disease and the person. This mantra is demonstrated in theway John practices science. As a basic researcher, heinvestigates the molecular mechanisms that regulate the cellcycle, an integral system that, when it goes awry, may causecancer. As a translational biologist, John is using human celllines and animal models to develop a safer but more potentchemotherapeutic strategy to treat breast cancer. Finally, as apublic health educator, John is in constant communication withcommunity members to raise awareness about the dangersassociated with late-stage cancer detection, as well as thecutting-edge medical breakthroughs that can help patients.

Benefits to Society:Everyone deserves a long and fulfilling life that should not beshortened by cancer. John hopes that the research he conductstoday can lend insights into how cancer develops, and how itmay be treated. But John also understands that being sick ismore than just about biology and economy. It is also about thefamily and soul. Thus, John hopes that by taking severalapproaches to studying cancer, his therapies will be able totreat the disease and the patient for what they are, as they are.

Awards and Honors:Scripps Translational Science Institute’s TL1 Fellowship, 2013

Ellen Browning Scripps Foundation Fellowship, 2013

R. Daviline Carter Presidential Award for Best Manuscripts, 2ndplace, 2013

Richard G. Lambert Foundation for Education Award, 2012

Biological Sciences Student Association Service Award, 2011

Publications and Posters:Tat et al. Strategy for disseminating tobacco controlinformation to Asians and Pacific Islanders. J Canc Educ.advance online publication, 28 Jun 2014.

del Rincón et al. Cks overexpression enhanceschemotherapeutic efficacy by overriding DNA damagecheckpoints. Oncogene. advance online publication, 26 May2014; doi:10.1038/onc.2014.1377.

Farber-Katz et al. DNA damage triggers Golgi dispersal viaDNA-PK and GOLPH3. Cell. 2014 Jan 30:156(3):413-27.

Zheng et al. A posttranslational modification cascade involvingp38, Tip60, and PRAK mediates oncogene-induced senescence.Mol Cell. 2013 Jun 6;50(5):699-710.

32

Page 35: ARCS® Foundation, Inc., San Diego Chapter

CALI TURNER TOMASZEWICZUniversity of California, San DiegoDivision of Biological SciencesDegrees:MAS in Marine Biodiversity andConservation, University of California,San Diego, Scripps Institution of OceanographyB.S. in Environment, Economics & Politics, Claremont McKenna College

Scholar Sponsors:ARCS Foundation and ARCS Endowment Fund

About the Scholar:Cali uses two techniques, skeletochronology and stable isotopeanalysis, to investigate the migration and habitat-use patterns oftwo endangered species of sea turtles in the Pacific, the greenturtle (Chelonia mydas) and the loggerhead turtle (Caretta caretta).These turtles are listed as endangered on the International Unionfor Conservation of Nature (IUCN) Red List and by the U.S.Endangered Species Act (ESA). Both are significantly impacted byfisheries along the West Coast of the U.S. and Mexico. Herresearch is focused on helping to reduce the impact of thesefisheries on the protected sea turtle populations. This research isconducted in partnership with NOAA’s National Marine FisheriesService, and findings from Cali’s research are directly applied tonational and international conservation management.

Benefits to Society:Cali’s research focuses on two populations of endangered sea turtlespecies: the green turtle (Chelonia mydas) and the loggerhead turtle(Caretta caretta), which inhabit the Eastern Pacific Ocean and areprotected under the Endangered Species Act. Effective conservationof these long-lived animals is limited by our lack of understandingof where in the ocean these animals live, and for how long theyinhabit each of these ocean regions. These are important aspects tounderstand, because the threats the animals encounter – like fishingnets, pollution, and boat strikes – all differ among different habitats(open ocean vs. near shore regions). By using the humerus bonesfrom dead-stranded marine turtles, Cali is uncovering patterns ofthese animal’s habitat use, age, and overall life history patterns. Sherecently determined that loggerhead turtles spend over 20 years in aspecific high bycatch region near Baja, Mexico, and this results in aless than 10% chance of these turtles reaching maturity. This workhas since been applied to critical international management efforts,as it emphasizes the importance of protecting these turtles whilethey inhabit this very important specific habitat. Current work isdirected at similar objectives for green turtles in the eastern Pacific.

Awards and Honors:UCSD NIH Cellular and Molecular Genetics Training Grant NOAA NMFS Stock Assessment Improvement PlanArchie Carr Student Award for Best Biology Oral Presentation; 2014 SeaTurtle Biology & Conservation SymposiumJeanne Messier Memorial FellowshipHearts di Vite Research Scholarship

Publications and Posters:Turner Tomaszewicz, C.; Seminoff, J.A. Turning off the heat: impacts of power plantdecommissioning on green turtle research. Coastal Management Journal 2012,40(1):73-87.

Turner Tomaszewicz, C.; Seminoff, J.A.; Avens, L.A.; Goshe, L.R.; Peckham, S.H.;Kurle, C.M. Habitat use of north pacific loggerhead turtles (Caretta caretta) andduration spent in a bycatch hotspot area near Baja California Peninsula usingskeletochronology and stable isotope analysis. Sea Turtle Biology & ConservationSymposium, New Orleans, LA.; April 14-18 2014.

Turner Tomaszewicz, C.N.; Seminoff, J.A.; Avens, L.A.; Goshe, L.R.; Peckham, S.H.;Rodriguez-Baron, J.M.; Bickerman, K.; Kurle, C.M. Determining age and residencyduration of loggerhead turtles at a North Pacific bycatch hotspot usingskeletochronology. (In Preparation).

Turner Tomaszewicz, C.N.; Seminoff, J.A.; Ramirez, M.; Kurle, C.M. A standardizedmethod for sequentially sampling annual bone growth layers for stable isotopeanalysis. (In Preparation).

STEPHANIE WENGUniversity of California, San DiegoBiomedical Sciences GraduateProgram, School of Medicine

Degrees:B.S. in Microbiology, University ofCalifornia, Santa Barbara

Scholar Sponsor:ARCS Foundation

About the Scholar:Stephanie is investigating the mechanisms of t(8;21) AcuteMyeloid Leukemia (AML) development. She is particularlyinterested in understanding how loss of a sex chromosome,which is observed in around 50% of these patients,contributes to the disease. The goal of her research is tobroaden our current understanding of and reveal importantgenes and/or pathways that are involved in driving thisdisease. With this new knowledge, the hope is thatimproved therapeutic strategies can be developed to morespecifically and efficiently target this form of cancer.Stephanie enjoys live music, going to the beach, traveling,and trying new food.

Benefits to Society:Acute myeloid leukemia (AML) is the most common form ofleukemia affecting adults. The t(8;21) mutation is observedin around 12-15% of AML patients. Although t(8;21) AML isconsidered to be a good-prognosis leukemia, there hasbeen little advancement toward the treatment of thisdisease and around 50% of patients eventually relapse.Stephanie’s research aims to improve our understanding ofdisease development and progression so that noveltargeted t(8;21) AML therapies can be developed in effortsto reduce relapse rates.

Awards and Honors:NIH Cancer Cell Biology Training Grant

Best Poster Award at the Biomedical Sciences ProgramRetreat

Publications and Posters:Weng S.; Matsuura S.; Mowery C.; Lam K.; Scholl, A.; LoM.C.; Zhang D.E. AML1-ETO Hematopoietic Stem ProgenitorCells display a hypersensitivity to GM-CSF which reducesleukemogenic potential. (In preparation)

Lam K.; Muselman A.; Du R.; Harada Y.; Yan M.; Matsuura S.;Weng S.; Harada H.; Zhang D.E. Hmga2 is a direct targetgene of RUNX1 and regulates expansion of myeloidprogenitors. Blood. 2014, 124(14), 2203-12.

Arimoto K.; Burkart C.; Yan M.; Ran D.; Weng S.; Zhang D.E.Plakophilin-2 Promotes Tumor Development by EnhancingLigand Dependent and -Independent Epidermal GrowthFactor Receptor Dimerization and Activation. Molecular andCellular Biology. 2014, 34(20), 3843-54.

Dekelver R.C.; Lewin B.; Weng S.; Yan M.; Biggs J.; ZhangD.E. RUNX1-ETO induces a type I interferon response whichnegatively effects t(8;21)-induced increased self-renewaland leukemia development. Leukemia & Lymphoma. 2014,55(4), 884-891.

33

Page 36: ARCS® Foundation, Inc., San Diego Chapter

MATTHEW WINGERTUniversity of California, San DiegoJacobs School of Engineering

Degrees:M.S. in Mechanical Engineering,University of California, San Diego

B.S. in Mechanical Engineering, University of California, Santa Barbara

Scholar Sponsor:Marti & Larry Showley

About the Scholar:Matthew studies nanoscale materials that are 1000s oftimes thinner than the thickness of a human hair. At thesesizes (10-100 nanometers or billionths of a meter), thephysical properties of the material are highly dependent onsize and shape compared to macroscopic (observable withthe naked eye) scale versions, such as their ability totransfer heat. His goal is to measure the properties ofnanostructures at these small scales and discover the exacteffects of size constraints on their ability to transport heat.

Benefits to Society:At the nanoscale, the properties of materials can vary greatlyfrom that of their bulk counterparts. By studying the changesin these properties in materials at smaller length scales, wecan identify and understand new physical phenomena. Asnanostructures are confined to smaller sizes, heat transportthrough the structures becomes greatly reduced or increasedcompared to macroscopic materials. Matthew’s goal is tomeasure the thermal properties of nanomaterials at new sizescales, as small as several nanometers, and improve ourunderstanding of nanoscale heat transport.

Awards and Honors:Initiation into Tau Beta Pi honor society.

Publications and Posters:Wingert, M. C.; Chen, Z. C. Y.; Dechaumphai, E.; Moon, J.;Kim, J.; Xiang, J.; Chen, R. Thermal Conductivity of Ge andGe-Si Core-Shell Nanowires in the Phonon ConfinementRegime. Nano Lett. 2011, 11, 5507-5513.

Wingert, M. C.; Chen, Z. C. Y.; Kwon, S.; Xiang, J.; Chen, R.Ultra-sensitive Thermal Conductance Measurement of One-dimensional Nanostructures Enhanced by DifferentialBridge. Rev. Sci. Instrum. 2012, 83, 024901.

Zheng, J.; Wingert, M. C.; Dechaumphai, E.; Chen, R. Sub-picowatt/kelvin resistive thermometry for probingnanoscale thermal transport. Rev. Sci. Instrum. 2013, 84,114901.

Zhong, Z.; Wingert, M. C.; Strzalka, J.; Wang, H. H.; Sun, T.;Wang, J.; Chen, R.; Jiang, Z. Structure-inducedenhancement of thermal conductivities in electrospunpolymer nanofibers. Nanoscale 2014, 6, 8283-8291.

CHRISTINE WITTICHUniversity of California, San DiegoJacobs School of EngineeringDegrees:M.S. in Structural Engineering,University of California, San Diego B.S. in Civil and EnvironmentalEngineering, Lafayette College

Scholar Sponsors:ARCS Foundation/Betty Jo Williams

About the Scholar:Christine studies the response of large, freestandingstructures to seismic excitation. This class of structuresincludes various mechanical and electrical equipment, nuclearradiation shields, as well as marble statues. These structureshave repeatedly been shown to respond poorly during post-earthquake reconnaissance. In an effort to develop predictivetools for their seismic response, Christine has conductedextensive shake table testing campaigns at UC San Diego’sPowell Laboratory. The results of these experiments are usedto validate three-dimensional multi-modal numerical models.Her primary objective is to develop a series of easy-to-usepredictive tools for the non-engineering community as well asrecommended actions for seismic mitigation. Outside of thelaboratory, Christine enjoys running, cooking, and spendingtime with friends and family.

Benefits to Society:Recent earthquakes highlight the vulnerability offreestanding structures to even moderate seismic events inwhich no damage to buildings is observed. Failure of thesestructures can result in reduced functionality of criticalfacilities (e.g. hospitals), damage to an irreplaceable artifact,and even loss of life. These freestanding structures aretypically not designed to withstand earthquakes.Furthermore, maintenance of these components is typicallyhandled by non-engineers. Christine’s research aims tofurther understand the behavior of these complex structures,develop predictive tools that determine their vulnerability,and provide recommendations as to their restraint topreclude failure during future earthquakes.

Awards and Honors:National Science Foundation Integrative Graduate Researchand Education TraineeshipPoster Award, Jacobs School of Engineering Research Expo2013The Moles National Construction Organization ScholarshipMarquis Scholar, Lafayette College Sigma Xi

Publications and Posters:Wittich, C.E.; Hutchinson, T.C. Shake table tests of stiff, unattached,asymmetric structures. Earthquake Eng. Struct. Dyn. (submitted)

Wittich, C.E.; Hutchinson, T.C.; Wood, R.L.; Seracini, M.; Kuester, F.Characterization of Full-Scale Human-Form Culturally Important Statues:A Case Study. J. Comput. Civ. Eng. (submitted)

Wittich, C.E.; Hutchinson, T.C. Development of a Rocking-Period CenteredProtocol for Shake Table Testing of Unattached Stiff Components.Proceedings of 10th National Conference in Earthquake Engineering,2014.

Wittich, C.E.; Hutchinson, T.C. Computing Geometric and Mass Propertiesof Statues for Rigid Body Rocking Analysis. Proceedings of ASCEInternational Workshop on Computing in Civil Engineering, 2013.

34

Page 37: ARCS® Foundation, Inc., San Diego Chapter

35

What Does this Award Mean to You?

Grant AllenThis award is extremely honoring. It’s the first seriousaward I’ve ever received (and possibly the best I could). I accept it as a portent for even stronger and morevaluable research still to come.

Monica Chu I am thankful for the generosity of the ARCSFoundation and ARCS sponsors. It means a lot to methat people continue to believe in me as a youngresearcher, and I feel grateful to be renewed as anARCS scholar this year. The Award will lessen myfinancial burden, enabling me to attend and presentmy research at conferences this year.

Mike Denny, Jr. I am honored to have been chosen for this award. I amexcited to have the opportunity to share my science andlearn about the work of other awardees. I believe thatbeyond doing the science, effective communication ofthat science outside of the lab is essential and, asscientists, it is our responsibility to society to do so. Thisaward helps address the practical concerns of graduateschool, so that I can continue to do good work andcommunicate it beyond the lab.

Danielle GrotjahnI am extremely grateful to receive the ARCS Foundationaward. This prestigious award will not only open up newand exciting networking possibilities for me, but it willalso help ease the financial burden I face while pursuingmy PhD. As a student growing up with a disadvantagedeconomic background, I assumed full responsibility topay for my education and living expenses sincegraduating high school. As an undergraduate, I receivedseveral scholarships and grants to help pay for myundergraduate tuition; however I still had to take outstudent loans to offset tuition costs. The award willalleviate some of the financial stress I have facedthroughout my life and also will allow me to pay offstudent loan debt while in graduate school.

Deanna JohnstonThe ARCS scholarship is an honor to receive. It first andforemost means that I get to be a voice for the nursingprofession in the specialty of research. I am honored tobe able to spread the word about the importance ofresearch in the nursing profession and the world of

healthcare. It also means that I can focus my energy onsuccessfully completing the PhD program with lessfinancial burden.

Eiren JacobsonThe ARCS Foundation award will allow me to pursueresearch projects that will improve the quality of mydoctoral dissertation and to travel to conferences that Iwould otherwise be unable to attend. This award willsignificantly impact my career by allowing me toproduce high-quality science and to share that sciencewith colleagues at national and international meetings.

Trevor JoyceI am very honored and grateful for the interest shownby the ARCS Foundation in my graduate education andresearch projects. This award has provided wonderfulopportunities to meet interesting colleagues acrossmany disciplines. I also am very grateful for the ARCSfunding that has allowed me to travel to severalconferences that have expanded my professionalnetwork.

Colette SmirniotisI am truly excited and honored to be the recipient of anARCS Foundation Award. Being named an ARCSScholar puts me among an impressive group of peersand gives me access to a network of professionals.Thisaward puts me closer to my career goals both inalleviating some of the financial pressures that comewith being a student and also in the prestige associatedwith an award from a national foundation.

Stephen RiceThe ARCS Foundation award is an honor which hasplayed a significant role in my education and research. Ithas allowed me to support myself during field research,expand my research sites, obtain additional training inlaboratory and analytical methods, and allow time in myschedule for the mentoring of undergraduates.Thisaward has meant that I’ve not had to pursueextracurricular employment and instead I have beenable to focus on my long-term career goals as well offeradvanced training and mentoring to my lab mates andundergraduates interested in molecular geneticsprojects. Thus this award has not only had positiveimpacts within my own life, but its area of effect hasbeen extended to other students as well.

Page 38: ARCS® Foundation, Inc., San Diego Chapter

36

ARCS® Foundation, Inc.Achievement Rewards for College Scientists

About UsARCS Foundation is a nonprofit organization founded and administered entirely by women who see a national

problem and are taking the initiative to try to solve it. The organization’s aim is to address this country's most critical

competitiveness issue: the serious shortage of American scientists and engineers. We address this issue by providing

financial awards and encouragement to men and women working to complete their degrees in science, engineering,

and medical research.

Since its founding in 1958, ARCS Foundation has grown to 16 chapters nationally and invested more than $91 million

in the potential of nearly 9,000 of the most outstanding American graduate and undergraduate Scholars in science,

engineering and medical research at 54 of the country's top research universities. Since 1985, the San Diego chapter

alone has contributed nearly $9 million in support of Scholars at our four ARCS-approved recipient institutions:

San Diego State University • The Scripps Research Institute

University of California, San Diego • University of San Diego

We are very proud of what ARCS Foundation has accomplished.

We know that we have a mission that is important to our

country's economic recovery, our global tech-

nological leadership, and ultimately the well-

being and quality of life for all people.

About Our ScholarsARCS Scholars represent an elite group of

students selected by their faculty for their

recognized achievements and for their

exceptional promise to contribute

substantially to their fields. These Scholars

represent America’s future. San Diego ARCS

Scholars can boast of a 98% graduation rate,

compared with the national rate for graduate

students in the sciences and engineering of 60%.

Funds invested in our Scholars pay dividends for

generations to come.

Scholar SelectionScholars must be U.S. citizens and meet ARCS-established academic criteria of a 3.5 GPA pursuing undergraduate

and graduate degrees in a wide range of subjects. Beyond the general area of science, engineering and medical

research, these Scholars are specializing in astronomy, biochemistry, botany, cell and molecular biology, chemistry,

computer science, ecology, engineering, genetics, marine biology, mathematics, oceanography, physics and more.

During 2015-2016 ARCS is pleased to support 62 Scholars for a total of $445,000.

ARCS MissionARCS Foundation advances

science and technology in the

United States by providing financial

awards to academically outstanding

U.S. citizens studying to complete

degrees in science, engineering

and medical research.

Page 39: ARCS® Foundation, Inc., San Diego Chapter

37

Ways to Help ARCS Foundation Scholars100% of each contribution is directed to the Scholar Award Fund.

ARCS Foundation provides a unique vehicle for supporting scholars in science, medicine, and engineeringwithout incurring administrative overhead. Member dues and event underwriting cover all operating expenses,and members donate their time to provide most administrative services.

There are two ways to support ARCS scholars studying to complete their degrees in science, medicine, andengineering. The first is to make an annual gift to the Scholar Award Fund. The entire amount is awarded within ayear of receipt. The second way to support scholars is through a gift to the Endowment Fund. The principalcontinues to accrue interest in perpetuity; scholar awards are made from the interest.

I. Annual Gifts to the Scholar Award FundGifts to ARCS Foundation Scholar Award Fund support continuing and new scholars at San Diego StateUniversity, The Scripps Research Institute, University of California, San Diego, and University of SanDiego. Gifts to the Scholar Award Fund may be made by check, credit card, or through gifts of appreciatedsecurities. Gifts received during the fiscal year (July 1 - June 30) are awarded at the beginning of thefollowing academic year.

II. Gifts to ARCS Foundation Endowment FundGifts to ARCS Foundation Endowment build an investment fund, the earnings of which provide apermanent source of income essential for supporting a portion of the Award Fund in perpetuity. Wheneveran Endowment grows by $150,000, the interest earned generates a $7,500 award. The Virginia Lynch GradyFund, the Wally Schirra Memorial Endowment Fund and the ARCS Endowment Fund are examples ofpermanently endowed Scholar Awards.

ARCS Legacy Society: ARCS Legacy Society comprises donors who have provided for ARCS Foundation in their

estate plans, thereby insuring the future of ARCS Scholars. For further information about how to become a

member of the Legacy Society, contact Patty Fuller at (858) 336-8191.

Memorial & Honorary Gifts: Gifts may be made in memory of a loved one or in recognition of an individual on the

occasion of a birthday, anniversary, or special event. All memorials and honoraria help build the Endowment.

To Give OnlineGo to the ARCS website: www.arcsfoundation.org/san_diego.

Click the turquoise “Donate” button found at the bottom of this homepage. Then click the blue “Donate Now” button found at the bottom of the linked page.

FOR MORE INFORMATION, PLEASE CONTACT:

Mary Fitz | President | [email protected] | (619) 298-7193

or

Joy Kirsch | Vice President, Fund Development | [email protected] | (858) 453-5449

ARCS Foundation, Inc., San Diego Chapter | P.O. Box 8394, Rancho Santa Fe, CA 92067-8394

Website: www.arcsfoundation.org/san_diego | Email: [email protected]

A Nonprofit Charitable Organization | Federal I.D. No. 33-0164533 | Corporate No. 1367672

Page 40: ARCS® Foundation, Inc., San Diego Chapter

ARCS® Foundation, Inc., San Diego ChapterMAJOR DONORS

Cumulative Gifts 1985 through June 2015

STELLAR BENEFACTORS – $1,000,000 AND ABOVEThe Reuben H. Fleet Foundation Fund

Virginia Lynch Grady

GALAXY BENEFACTOR – $500,000 AND ABOVEThe Donald C. & Elizabeth M. Dickinson Foundation

ALBERT EINSTEIN PATRON – $250,000 - $499,999Blasker-Rose-Miah Fund

International Systems, LLC/Allan Wegner and Bob Whalen

THOMAS EDISON PATRON – $100,000 - $249,999

MARIE CURIE CIRCLE – $50,000 - $99,999

GALILEO CIRCLE – $25,000 - $49,999

The Thomas C. Ackerman FoundationThe Beyster Family Foundation

The Favrot FundKathryn Crippen Hattox Fund

Hervey Family Non-endowment FundThe Legler Benbough Foundation

Dale & Marge Myers FundMargaret L. Roulette

Ellen Browning Scripps FoundationTimken-Sturgis Foundation

Union BankWD-40 Company

Carlos & Sharon ArbelaezThe Atkinson Family Foundation

Emily BagnallKaren & Bob Bowden/Bowden Family Foundation

Cubic CorporationCymer, Inc.

Dr. Charles C. & Sue K. Edwards FoundationSamuel H. French III & Katherine Weaver French Fund/

Maurice J. Masserini Charitable TrustCecil & Ida Green Foundation

Jack HeckelJackie Leisz

The Collins Companies Foundation/Diane & Tyler MillerThe Parker Foundation

Pfizer La JollaScience Applications International Corporation (SAIC)

Marti & Larry ShowleyPat & Bob Whalen

Betty Jo & Hal Williams

Charles and Ruth Billingsley FoundationKenneth & Marjorie Blanchard

The Burnham FoundationConexant Systems, Incorporated

The Education Financing Foundation of CaliforniaBecki and Ed EtessJeanette Foushee

The Samuel I. & John Henry Fox FoundationConnie K. Golden

The Heller Foundation of San DiegoJanet and Dan La Marche

Lambert Foundation for Education at Union Bank

Dr. & Mrs. William McCollNancy and Bill Norgren

Oak IndustriesThomas and Audrey Pine Foundation

Mrs. Walter J. PodbielniakThe George Smedes Poyner FoundationMrs. Donald Roon/Roon Foundation, Inc.

Lois S. ThompsonThe Thursday Club Foundation

Titan CorporationThe Robert G. and Gloria R. Wallace Family

Wells Fargo Bank

Our greatest gratitude to these major donors who have made a significant contribution to the future of science, engineering and medicine by supporting ARCS Scholars.

=The San Diego Foundation

= Fund Managed by Union Bank

The above amounts include donations to the ARCS Awards and Endowment Funds.

38

Page 41: ARCS® Foundation, Inc., San Diego Chapter

39

2014-2015 Donor Honor RollSAN DIEGO CHAPTER • JULY 1, 2014 – JUNE 30, 2015

Gifts received for awards to be made in the Academic Year 2015 - 2016

$50,000Reuben H. Fleet

Foundation Fund

$30,000Hervey Family

Non-endowment Fund

$22,500Beyster Family

Foundation Fund IV

$15,000The Donald C. & Elizabeth M.

Dickinson FoundationThe Roche Foundation

Ellen Browning ScrippsFoundation

$7,500 - $9,999The Thomas C. Ackerman

FoundationSharon and Carlos ArbelaezThe Blanchard Foundation

Cymer, Inc.The Farrell Family Foundation

Dottie GeorgensKathryn Crippen HattoxThe Heller Foundation

of San DiegoLambert Foundation forEducation at Union Bank Marti and Larry Showley

The Timken-Sturgis FoundationWD-40 Company

$5,000 - $7,499Cindy and John Glancy

Helen W. and Webster B. Kinnaird

Elizabeth (B.J.) WilliamsMara and Larry Ybarrondo

$2,500 - $4,999Karen and Bob BowdenThe Samuel I. and John Henry Fox Foundation

Susan Hoekenga and Edward Gergosian

The Arthur and Jeanette Pratt Memorial Fund

$1,000 - $2,499Janet Allison

Emily T. BagnallBarbara Bry and Neil Senturia

The Burnham FoundationJoyce Butler

Joan and Milt EvangelouSally and Parker Finch

Nancy Reed GibsonThe Ellen Kathleen Glynn

FoundationBetty HarrimanAndrew Hewitt

Greg LucierVADM and Mrs. William

McCauleyBarbara and

Dr. William McCollHelga Moore

Dale and Marge Myers FundNuvasive, Inc.

Marti and Frank PanarisiTanya SchierlingDr. Jane K. Smith

Patricia Brander StewartJudge and Mrs. Gordon

Thompson, Jr.RADM and Mrs. Guy Zeller

$500 - $999Barbara and Charles Arledge

Nancy Lee BildsoeDiane Annala Chalmers

June ChochelesBarbara Doren

Doris and Peter K. EllsworthBecky Etess

Mary and Dr. David FitzJoy Frye

Dr. Cindy GoodmanBea HadingerPeggy HanleySandra HarrisHolly Heaton

Marjorie J. and Paul W. Hebert,Jr.

Norma Hidalgo del RioAnn HillPeter Ho

Linda JohnsonLockheed Martin

Mary and Dan MulvihillGloria McColl Powell

Astrid ShannonBobbie and Richard Vandervoort

Gayle Wilson

Up to $499Connie AdelmanBenedict AdelsonNancy Anderson

Christine AndrewsLinda Andrews

Lyndsey ArendseeKatherine Armagnac

Kim BarrettWilliam BeamerBeth Bernstein

Jim BeysterGerry Black

Pamela BoytonBetty Brayshay

Joy BrownAlice Brown

Kathleen BuoymasterSuzanne CamilliRichard CassoniVirginia ChaseyPerry Colapinto

Jean and Michael CollinsGordon Cooke

Andrea CorrentiMartha DennisSuzanne DixonKimberly Doren

Berit Durler German Eichberger

Ann EsteeJeanette Foushee

Rachel C. FriedmanJames FrielFrank FryeKim FullerPatti Fuller

Chris GlemotskiChristine Gutheil

Peggy Hanley Leslie Harrington

Barbara and James HartungJan Hawkins

Phyllis HaynesChristopher HebertNancy HerringtonReena HorowitzEthel W. IversonNancy B. James

Kim and Fred JohnsonSusan Jones

Joy KirschDr. Candace Kohl

Stella LarsenYvonne Larsen

Jeanne and Bill LarsonRobert Lawson

Sharon LeeMasterJohn Love

Robin and Chuck LubyKaren Ludwig

Deborah and Fred MandabachDiane J. Marinos

Lynne MartinAdrienne McCullough

Dr. and Mrs. William McDadeKimberly Miller

Diane and Ty MillerEllen Moxham

Priscilla MoxleyJillian Mullen

Kathryn MurphyGail Naughton

Steve NielanderPerry Nisen

Ann OttersonGene Pastula

Betty L. PeabodyPeter Pierce

Sue PondromMary Lou and Harry Quick

Sharon RhodesEdwina RibletJennifer RoachDr. Linda RouxCarol Rumsey

The San Diego FoundationJerrie L. Schmidt

Mrs. John F. ShawAnn Silliman-Holmes

Leslie SmartMarianne Sorge

Ann SteckIlene Swartz

Karen and Don TartrePaula A. TaylorSally Thomas

Mary WalshockDavid P. Wells

Pat WhalenVirginia Whitelock

Karen WinsonJulie Wright

=The San Diego Foundation

= Fund managed by Union Bank

The amounts above include donationsto the ARCS Foundation ScholarAward Fund, Endowment, and

Memorial Funds as of June 30, 2015.

See an error or omission? Pleasecontact Norma Hidalgo del Rio

[email protected]

Page 42: ARCS® Foundation, Inc., San Diego Chapter

40

2015-2016 Community Advisory Council

The purpose of ARCS® Foundation, Inc. San Diego Chapter Community Advisory Council (CAC) is to assist the

organization in achieving its mission. The CAC is composed of distinguished professionals drawn from diverse

science and technology industries represented in San Diego. Through the members of the Council, the chapter has

access to a larger network of individuals, businesses and professional organizations interested in the advancement of

science and technology. They help the chapter accomplish its goals, promote activities and facilitate fundraising. For

the ARCS Scholar, the Council organizes activities that enrich the Scholars’ professional experience and serves as a

bridge to the entrepreneurial community. We thank them for their continued support.

Diane Klotz, Director, Office of Training & Academic Services,

Sanford Burnham Prebys Medical Discovery Institute

Chairman

Dr. Stephie Althouse, CEO Coach & Visiting CEO

Jon Berg-Johnsen, Corporate Business Development, Lockheed Martin Corporation

Liisa Bovinovic, Executive Director, BIOCOM Institute

Nicholas Burchfield, Director, Corporate and Foundation Relations, The Scripps Research Institute

Willliam Burfitt, Executive Director, Development, Jacobs School of Engineering

Katie Collins, Director of Development, J. Craig Venter Institute

Maria Fischer, CEO, Bientech International

Patty Fuller, Philanthropy Consultant, Fuller Communications

Suzanne Graham, Sr. Manager, Business Development, Genection

Andrew Hewitt, Managing Partner, Continuity Partners, LLC

Pat Kelly, Vice President, Educational Committee Chair, Sonalysts, Inc., & VP of Education, AFCEA

Terry Magee, Consultant, Defense Sector

Terry McKearney, President, The Ranger Group

Ginny Merrifield, Chief Operating Officer, CONNECT

Terry Moore, Managing Partner, Moore Venture Partners LP

Karen Winston, VP Partnerships, POSIBA

Page 43: ARCS® Foundation, Inc., San Diego Chapter

Connie AdelmanJanet AllisonNancy AndersonMary Beal Angel

* Sharon ArbelaezBarbara ArledgeKatherine “Kit” ArmagnacRita AtkinsonEmily BagnallPat BeckBetty BeysterJudy BielerNancy Lee BildsoeMarla B. BlackKaren BowdenElizabeth "Betty" Brayshay

* Alice BrownJoy BrownBarbara BryKathleen "Kathy" BuoymasterSue Busby

* Diane Annala ChalmersJune ChochelesPerry Anne ColapintoJean CollinsLinda CopsonAndrea L. “Andy” CorrentiCarolyn Patton DetwilerSuzanne Dixon-HennessyBarbara DorenKim DorenBerit DurlerCarolyn Elledge-BakerDoris EllsworthBecki EtessJoan EvangelouJane FetterSally Shafer Finch

** Mary FitzGeorg’Ann FletcherKaren FontanaJeanette FousheeMarye Anne FoxRachel Collins FriedmanJoy Frye

Patricia Carroll “Patty” FullerHolli Garrett

* Dottie GeorgensNancy Reed GibsonCindy GoodmanBeatrice "Bea" Hadinger

* Margaret "Peggy" HanleyBetty HarrimanSandra HarrisKathryn "Kathy" HattoxPhyllis HaynesHolly Heaton

* Marge HebertJoanne HerrinNancy HerringtonNorma Hidalgo Del RioAnn HillJeri HirshmanAnn Silliman HolmesSandra Fleet HonnenReena HorowitzElizabeth "Betty" HubbardColey HuntEthel W. IversonNancy James

* Linda Johnson* Joy S. Kirsch

Candace KohlMaureen LambertiSharon LeeMasterAnn LemkeNicola Green LernerJacqueline “Jackie” LinstromRobin Briscoe LubyKaron T. LuceKaren LudwigMary E. LyonsDeborah MandabachDiane MarinosLynne MartinMary Ann McCauleyBarbara McCollCarol McDadeDiane MillerKimberly Miller

* Helga S. MooreEllen MoxhamPriscilla MoxleyMary MulvihillJanet MunsonToni Woodward NickellMarti PanarisiBetty PeabodyChan Poyner Pike

* Sue PondromGloria D. McColl Powell

* Mary Lou QuickPaula RaySharon Lee RhodesEdwina RibletLaurie RoederMargaret “Marge” RouletteLinda RouxCarol RumseyMary Sadler

* Tanya SchierlingJerrie SchmidtJanice "Jan" ShawMarti ShowleyBetty SimmJane SmithPatricia Brander "Pat" StewartTamia E. StrachanIlene SwartzJean TalbotKaren M. TartreSarah Margaret “Sally” ThomasJean ThompsonLois S. ThompsonBarbara “Bobbie” VandervoortWalther-Meade, Yolanda Pattie Wellborn

Betty Jo "BJ" WilliamsGayle WilsonMara YbarrondoBritt Zeller

** President * Board of Directors

2015-2016 ARCS® Membership

Page 44: ARCS® Foundation, Inc., San Diego Chapter