Applied Biosystems Informatics Solutions for the Life Sciences

Jason McGlashan

Oracle® Life Science User Group Meeting

Company Overview• 20-year history of fueling life science innovation

• Instruments and reagents — over 50,000 instrument systems installed in over 100 countries

• Informatics solutions — 1000 installed sites

• global partner since 1986• LIMS• ABI PRISM® 3700 and Applied Biosystems 3730 DNA Analyzers

and ABI PRISM® 3100 and 3100-Avant Genetic Analyzers• New TaqMan® Gene Expression and Genotyping Assays• Proteomics applications• Celera Discovery System™ database

Enabling Integrated ScienceTo better understand the complex interaction of biological systems, life scientists are developing revolutionary approaches to discovery that unite technology, informatics, and traditional laboratory research.

In partnership with our customers, Applied Biosystemsprovides the innovative products, services, and knowledge resources to make this new, integrated science possible.

Applied BiosystemsInformatics Software and Services

TargetDiscovery

Target Validation Pre-Clinical Clinical

Research

INFORMATICS SOLUTIONS

Manufacturing

• From discovery to manufacturing• LS*LIMS™ Software and SQL*LIMS® Software

• Proven experience and services• Enabling Integrated Science

LS*LIMS™ Software for Integrated Science

Integrate and automateinstruments

Integrate data from

different sources

Simplify workflow

management+ +

= Increased throughput and improved quality

Graphical Workflow Editor• Mirror your lab operations and data flow

• Easy-to-use drag-and-drop interface

• Out-of-the-box instrument interfaces

• Pre-configured activities and workflows

• Novel workflow engine

Flexible, Extensible System• Open, multi-tiered architecture

• Based on industry standards

• Software developer kit (SDK) and fully documented APIs

TM

Software Core Components

Workflow Management

Project Management

Assay/MarkerManagement

Applied Biosystems Software Architecture

SampleManagement

ResultManagement

Instrument Communication Interface

Power of Applied BiosystemsSoftware Architecture• Simplifies Applied Biosystems instrument and

application integration

• Provides common user experience across AppliedBiosystems instruments and applications

Workflow Management• Provide two interfaces for process-centric system

• Process Definition — define end-to-end lab workflow• Lab Console — manage and execute daily lab work

LS*LIMS™ Software in Your Laboratory

Applied Biosystems Informatics Technology Summary

LAN / HOST / Character Terminals

IntranetOracle 8 Objects

GUI Client / Server

TCP / IP Reporting/ events

OpenVMS

SQL*LIMS® v3 software

SQL*LIMS® v4 software

Oracle9i ObjectsOracle9iDatabaseReports

Web browsers

LS*LIMS™ softwareSQL*LIMS® v5 software

Microsoft Windows NT®

SQL*LIMS® v2 – 2.2 software

Benefits of Using Oracle®

• Scalability

• Compatibility

• Platform availability

• Security

• Global acceptance

Applera Corporation is committed to providing the world's leading technology and information for life scientists. Applera Corporation consists of the Applied Biosystems and Celera Genomics businesses.

Applied Biosystems develops and markets instrument-based systems, reagents, software, and contract services to the life science industry and research community.

Notice to Purchaser: License DisclaimerPurchase of this software product alone does not imply any license under any process, instrument or other apparatus, system, composition, reagent or kit rights under patent claims owned or otherwise controlled by Applera Corporation, either expressly or by estoppel.

Applied Biosystems, GeneMapper, SQL*LIMS, and ABI PRISM are registered trademarks and AB(design), Applera, iScience, iScience (Design), LS*LIMS, and Celera Discovery System are trademarks of Applera Corporation or its subsidiaries in the US and/or certain other countries. All other trademarks are the properties of their respective owners.

TaqMan is a registered trademarks of Roche Molecular Systems, Inc.

Applied Biosystems develops and manufactures its products in accordance with ISO 9001:2000 systems quality requirements.

©2004 Applied Biosystems. All rights reserved.