Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc...
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Transcript of Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc...
![Page 1: Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University.](https://reader033.fdocuments.us/reader033/viewer/2022061504/5a4d1b047f8b9ab059987e09/html5/thumbnails/1.jpg)
Antiphospholipid Syndrome
Ahmed Magdy Bedda, MD, PhDProfessor OphthalmologyRowayda M. Amin, MSc
Assistant Lecturer OphthalmologyAlexandria University
![Page 2: Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University.](https://reader033.fdocuments.us/reader033/viewer/2022061504/5a4d1b047f8b9ab059987e09/html5/thumbnails/2.jpg)
History 29 year old lady complaining of bilateral drop
of vision since 3.5 months history of preeclampsia and previous 2 attacks
of left lower limb thrombosis over the past 3 years
had been diagnosed with Antiphospholipid syndrome with positive lupus anticoagulant and anti-cardiolipin antibodies
![Page 3: Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University.](https://reader033.fdocuments.us/reader033/viewer/2022061504/5a4d1b047f8b9ab059987e09/html5/thumbnails/3.jpg)
Ocular examination
BCVA 4/60 OD 6/18 OS anterior segment was unremarkable fundus
wedge-shaped triangular choroidal hypoperfusion defects (Amalric sign)
with pigmentary changes in the setting of choroidal infarcts
![Page 4: Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University.](https://reader033.fdocuments.us/reader033/viewer/2022061504/5a4d1b047f8b9ab059987e09/html5/thumbnails/4.jpg)
Fundus at presentation
![Page 5: Antiphospholipid Syndrome Ahmed Magdy Bedda, MD, PhD Professor Ophthalmology Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University.](https://reader033.fdocuments.us/reader033/viewer/2022061504/5a4d1b047f8b9ab059987e09/html5/thumbnails/5.jpg)
Conclusion Amalric sign is a rare clinical sign that
indicates choroidal ischemia It is believed to represent occlusion of the
long or short posterior ciliary arteries (PCA) or their branches
Clinical entities such as malignant hypertension, chronic renal failure, toxemia of pregnancy, collagen vascular diseases, sickle cell disease and vasculitidis have been implicated