ANTI-BACTERIAL・ANTI-ODOR・ANTI-FUNGAL PANACEA … · Control on irritating odor Non-volatility...

CONFIDENTIAL

ANTI-BACTERIAL・ANTI-ODOR・ANTI-FUNGAL PANACEA PROPOSAL

2016

PANACEA, INC.,

Copy Right © PANACEA, INC., All Rights Reserved.

Concept

⚫Concept Achieving a Fuller Lifestyle that is Safe & Worry-Free


What is PANACEA?

Product Recommended by Okinawa Medical

Cooperative Association

Stabilized Unadulterated Sodium Hypochlorite

Agent

Viruses and Bacteria Kills 99.9% of germs!

Instantly deodorizes by eradicating odor！

Anti-fungal Effect Destroys mold spores

Fights Pollen! Reduces up to 88.2%

Fights Dust Mite Allergen （Prevention of

Atopic Dermatitis） Reduces up to

84.9%

Fights PM2.5！Air pollution particles

smaller than 2.5 microns

The word “Panacea” is a latin word that originated from Greek and means a cure-all; a remedy and a solution for all ills and difficulties.


Product Lineup

50mL Handy size that fits easily into purses or nurse uniform pockets.

Refill Pouch450mL Refill for the 500 mL bottles. Economical and a great deal.

500mL Popular 500 mL size. Wide range of uses from households to businesses.

5L For business use. All-purpose size, from refilling bottles to using in Panacea exclusive vaporizers.

20L For professional use. Perfect for use in large quantities.


Antibacterial Effect Ⅰ（VRE / Klebsiella pneumoniae / Legionella pneumophila / Listeria）

Antimicrobial Activity Test Results

Bacteria SubjectTotal Viable Bacterial Count (/ml)

Bacteria Subject Start 15 sec. 30 sec. 1 min.

Start 15 sec. 30 sec. 1 min.

VRE

Sample 1.1 x 10 ＜10 ＜10 ＜10

VRE

Sample

Control 1.1 x 10 ーー 1.0 x 10 Control ーー

Klebsiella pneumoniae

Sample 6.3 x 10 ＜10 ＜10 ＜10

Klebsiella pneumoniae

Sample

Control 6.3 x 10 ーー 5.7 x10 Control ーー

Legionella pneumophila

Sample 2.3 x 10 5.0 x 10 1.6 x 10 ＜100

Legionella pneumophila

Sample


Listeria

Sample 6.5 x 10 ＜10 ＜10 ＜10

Listeria

Sample


6

6

5

5

7

7

6

5

5 3

7

5

5 5


Antibacterial Effect Ⅱ（Pseudomonas aeruginosa / Salmonella / Staphylococcus aureus / MRSA）

Bacteria SubjectTotal Viable Bacterial Count (/ml)



Pseudomonas aeruginosa

Sample 1.0 x 10 ＜10 ＜10 ＜10

Pseudomonas aeruginosa

Sample


Salmonella

Sample 6.8 x 10 ＜10 ＜10 ＜10

Salmonella

Sample


Staphylococcus aureus

Sample 3.2 x 10 30 ＜10 ＜10

Staphylococcus aureus

Sample


MRSA

Sample 1.4 x 10 ＜10 ＜10 ＜10

MRSA

Sample


5

5

5

5

5

5

6

6 6

5

5

5



Antibacterial Effect Ⅲ（Staphylococcus epidermidis / Streptococcus / Vibrio parahaemolyticus）

Bacteria Subject

Total Viable Bacterial Count (/ml)



Staphylococcus epidermidis

Sample 7.3 x 10 2.3 x 10 10 ＜10

Staphylococcus epidermidis

Sample


Streptococcus

Sample 6.7 x 10 ＜10 ＜10 ＜10

Streptococcus

Sample


Vibrio parahaemolyticus

Sample 4.6 x 10 ＜10 ＜10 ＜10

Vibrio parahaemolyticus

Sample


5

5

5

5

5

5

5

5 5

5



Antibacterial Effect Ⅳ（O-157 / Norovirus）

Bacteria Subject


Bacteria Subject Start 30 sec. 1 min. 3 min.

Start 30 sec. 1 min. 3 min.

E coli. /O-157 /Verotoxin-

producing E coli.

Sample 1.3 x 10 ＜10 ＜10 ＜10E coli. /O-157 /Verotoxin-

producing E coli.

Sample


Virus Subject


Virus Subject Start 30 sec. 1 min. 3 min.

Start 30 sec. 1 min. 3 min.

Norovirus (Feline calicivirus)

Sample 3.2 x 10 ＜32 ＜32 ＜32

Norovirus (Feline calicivirus)

Sample

Norovirus cannot be photographed.

Control 3.2 x 10 ーー 3.2 x 10 Control

♦ Summary ① Within 15 sec. to 1 min. after spraying the test material on microbes that have an effect on human body, such as food poisoning bacteria, antibiotic-resisting bacteria and norovirus, the inactivation of component protein of the subjects was observed. ② No effect was observed with Bacillus cereus (spore), Bacillus subtilis, mold and yeast. ③ The test material has been proven to have no effect on the human body with the safety test (acute toxicity, eye and skin irritation test) conducted.

5

5 5

6

6 6



Antibacterial Effect Ⅴ（Parvovirus / Swine Transmissible Gastroenteritis Virus / Influenza Virus ）

Panacea disinfects problematic viruses

and bacteria found in [hospitals and clinics]

[nursing facilities] [restaurants] [households]

[schools] [pet and livestock surroundings] within

approximately 15~60 seconds.


Deodorizing Effect

Panacea instantly eliminates a wide variety of odors including the 8 major odors classified by the Ministry of the Environment. Unlike “masking,” which only covers up odors with other fragrances, “Panacea” eliminates odors through oxidative decomposition.

Ammonia Toilet Odor

Methyl Mercaptan Odor of Spoiled Meat

Hydrogen Sulfide Odor of Spoiled Eggs

Methyl Sulfide Odor of Spoiled

Vegetables

Trimethylamine Odor of Spoiled Fish

Dimethyl Disulfide

Odor of Spoiled Vegetables

Styrene Odor Caused by Burning Plastic

Acetaldehyde Cigarette Odor

Instantly Eliminates 8 Major Odors Classified by the Ministry of the Environment

Panacea® Panacea®Instantly Deodorizes

Disinfects in 15～60 sec.

Simultaneously

Instantly eradicates odor by breaking down the root cause of smell! Disinfects simultaneously!!

Deodorizes (Disinfects) footwear/shoe cabinets

Deodorizes (Disinfects) toilets/sinks

Deodorizes (Disinfects) pet surroundings

Deodorizes (Disinfects) refrigerators/ garbage cans

Deodorizes (Disinfects) rooms/closets/ linens/curtains

Deodorizes (Disinfects) cigarette smell/ inside cars

Strong Deodorizing Power of Panacea®!!


Fights Pollen

“Panacea” eliminates 88.2% of cedar pollen, which is one of the main causes of hay fever.


Fights Dust Mite Allergen

“Panacea” eliminates 84.9% of dust mite allergen, which is one of the main causes of atopic dermatitis and sick building syndrome.


Food Additive Specifications and Standards Compliance Test

“Panacea” has passed the Food Additive Specifications and Standards Compliance Test and has been proven to be safe even to spray directly on food.


Safety (Primary Skin Irritation Test / Acute Oral Toxicity Test / Eye Irritation Test)

Panacea is harmless to the human body!

This non-irritant solution can even be used without

worry in households and facilities where babies,

the elderly or pets are present.

Primary Skin Irritation Test

Acute Oral Toxicity Test

Eye Irritation TestBased on the results of tests conducted on rabbits,

which are more sensitive than humans, Panacea is classified as “non-irritant.”

During the testing conducted on male mice, which are more sensitive than humans,

no abnormalities or cases of death have been observed.


Based on the results of tests conducted on rabbits, which are more sensitive than humans, Panacea is classified as “non-irritant.”

Comparison of Effectiveness between Panacea and Competing Brands

機能性

種類

・Alcohol products have almost no sterilizing power outside of the 60~85 alcohol percentage range. Alcohol is also ineffective on the Norovirus. ・Though chlorine dioxide has a high sterilizing power, with its high oxidizability, it is corrosive to metals, electric equipment and home appliances. 　It produces a strong irritating odor and hazardous gases while also bleaching textile products. 　Under UN regulations, due to its strong corrosiveness to metals, chlorine dioxide is prohibited to be loaded on civil aircraft. 　Although it has not been listed on the comparison chart, stabilized chlorine dioxide (chlorine dioxide aqueous solution) has almost no sterilizing power. 　To achieve the sterilizing effect, acid needs to be added to the solution and left for more than 10 hours to convert to chlorine dioxide. ・Unlike existing sodium hypochlorite formulas, almost no deterioration in quality is found in “Panacea®.” It can maintain 98% of its effective chlorine 　concentration when stored in a cool and dark environment. It is as corrosive to metals as water is and exhibits no problems in regards to bleaching 　effects and irritating odors, making it safe and reliable.

Disinfecting Time

Disinfecting Power

Deodorizing Effect

Non-corrosive to

metals

Without bleaching effect

IncombustibilityControl on hazardous gases

Control on irritating odor

Non-volatility

Stability of quality

Environmental safety

Spraying in the air

Control of drug-

resistant bacteria

Alcohol based products ○ ○ × ◎ ◎ × × × × ○ × × ×Products

using chlorine dioxide

◎ ◎ × × × △ × × × × × × ○Products using

hypochlorous acid

◎ ◎ △ × × ○ × × × × × × ○Products using weak hypochlorous

acid◎ ◎ △ × × ○ △ △ × △ △ △ ○

Panacea® ◎ ◎ ◎ ○ ○ ◎ ◎ ◎ ◎ ◎ ◎ ◎ ◎


Comparison of Effectiveness between Panacea and Weak Acidic Sodium Hypochlorite <Follow-Up Study on Residual Chlorine Concentration>

Weak Acidic Sodium Hypochlorite Formula Even in an unopened state, the chlorine concentration (disinfecting effect) drops significantly to 1/3 of its original state, and becomes strongly acidic. It is extremely dangerous to spray into the air after deterioration has occurred (chlorine gas / trihalomethane / metal corrosion / bleaching effect / etc.)

Panacea® Even after a year, it maintains 99.9% of the chlorine concentration (disinfecting effect) and pH value of 10 at the weak alkaline state

and eventually becomes water.


Comparisons between PANACEA and Weakly Acidic Sodium Hypochlorite Solution

Copyright © 2016 PANACEA. INC., All Rights Reserved.

　　Conclusion:　　Due to their extremely unstable and questionable traits, we believe products containing weakly acidic sodium hypochlorite should be restrained from sales, when in fact, these products are currently used in hospitals and other medical facilities. After a month of use, various problems such as metal corrosion are discovered. We believe PANACEA is a product that can be completely distinguished from other competitors and from weakly acidic sodium hypochlorite products. It is a solely original product that is reliable and can be used without any concerns.

Duration of Observation PeriodAfter 1 week After 2 weeks After 4 weeks After 2 months

Chlorine Concentration

PANACEA 100% 100% 100% 100%Weakly Acidic Sodium Hypochlorite 87% 46% 31% less than 15%

Disinfecting Power

PANACEA ◎ ◎ ◎ ◎Weakly Acidic Sodium Hypochlorite ◎ △ × ×

Deodorizing Power


pH ValuePANACEA pH10 pH10 pH10 pH10

Weakly Acidic Sodium Hypochlorite pH5～6 pH4 pH3 pH3

Safety of Spraying in Air


Non-corrosive to Metal


Absence of Bleaching Effect


🌟 IngredientPANACEA 　Sodium Hypochlorite　＋　Alkaline Ionized Water in High Concentration

Weakly Acidic Sodium Hypochlorite 　Sodium Hypochlorite　＋　Dilute Hydrochloric Acid　＋　Citric Acid　＋　Water

🌟 Antibacterial Effects

PANACEA 　 Stabilized at the pH value of 10 in the weakly alkaline range, the antibacterial effect of PANACEA is stable for an extended period of time with the added effects of oxidative decomposition of OCL ions and hydrolysis of hydroxide ions. Evidence is available.

Weakly Acidic Sodium Hypochlorite

　Averages in the weakly acidic range of pH 6. Appeals its antibacterial effects by the maximum value of HOCL. However, the pH value declines to 3.5 from the 4th week onward. We believe the claims made of the product are extremely inaccurate.

Alcohol Formulas

ーDisinfecting Effects 　Alcohol demonstrates its maximum disinfecting power within a concentration range of 76.9~81.4%. Therefore, almost no sterilizing effect can 　be found when the concentration is 60% and below or 85% and above. 　The bacteria unaffected by alcohol formulas are a type of bacteria that produces spores (an extremely resistant cellular structure that can 　only be found in certain bacteria). Among these, the most well known are the anthrax bacteria, tetanus bacillus and also a number of other 　　bacteria that cause food poisoning such as Bacillus cereus, botulinus and Welch bacillus (including hay bacillus and natto bacteria). Due to 　　these bacteria and viruses’ extremely strong resistance to chemical agents, alcohol is unable to achieve the desired disinfecting and sterilizing 　effects. 　Viruses well known to be less susceptible to alcohol are non-enveloped viruses (about 80% of viruses have this covering structure and are 　relatively sensitive to and easy to sterilize with heat and chemical agents) such as norovirus, rotavirus, enterovirus that causes hand-foot-and-　mouth disease and herpangina and adenovirus that causes adenovirus infection.

ーAlcohol Resistance 　There is a surprising number of bacteria that can exist in alcohol. The fact that alcohol has no effect on norovirus, one of the main 　causes of food poisoning, is widely known. With the extensive use of alcohol in the medical field, the number of bacteria 　developing resistance to alcohol appears to be on the increase. In some cases, where alcohol cotton balls are prepared in advance, 　the alcohol concentration deteriorates as the alcohol evaporates. It has been reported that propagation of alcohol-resistant 　bacteria can be found especially in these containers of alcohol cotton balls.

ーPrecautions for Use 　・Alcohol is extremely irritative to mucous membranes and can possibly cause inflammation in people with sensitive skin. 　・Due to its combustibility, extreme caution is required when handling in kitchens and in other environments where fire is used. 　・Due to its strong irritating odor, it is not suitable for spraying in the air. 　・As the range of alcohol concentration which is effective against bacteria and viruses is extremely narrow, when applying to 　　objects that are wet, the moisture mixes with the alcohol, reducing its concentration therefore, neutralizing its ability to disinfect. 　・Caution is required when using alcohol on synthetic rubber, synthetic resin products, optical instruments, mirrors and painted 　　　surfaces, as it may cause changes.


Target Market

General Food　・Supermarkets　・General merchandise stores　・School meal suppliers　・Hotels　・Amusement facilities　・Food processing plants　・Poultry houses　・Restaurants　　（Any facility with a kitchen）

Medical Care　・Hospitals　・Clinics　・Nursing homes　・Self-defense forces　・Administrative agencies　・ Environmental companies

Miscellaneous Goods　・Drugstores / pharmacies　・Pet shops　・Baby goods stores　・DIY shops　・Convenience stores　・Duty-free shops

School　　・Infirmaries 　・Nurseries～graduate　　schools

Office Supplies　　　・Companies　・Catalog mail orders　・Stationery stores

　

Other　　・Cleaning companies　・Building maintenance　　companies　・Health centers　・Animal shelters

Overseas　・Previously mentioned 　companies / wholesalers


Summary

“Anti-bacterial・Anti-odor・Anti-fungal Agent Panacea” is “stabilized unadulterated sodium hypochlorite” that is recommended by the Okinawa Medical Cooperative Association.

Panacea is a revolutionary agent that is free of the inadequacies in existing weak acidic and slightly acidic sodium hypochlorite products such as “extremely short-term efficacy,” “metal corrosion,” “bleaching effect,” “chlorine gas emission” and “production of the carcinogen, trihalomethane.” Unlike other existing agents, the pH balance of Panacea does not become strong acidic after a short period of time. It also maintains its chlorine concentration for about 1 year, along with a pH value of about 10 in the weak alkaline range. It does not cause any damage to health, as it eventually only turns into water.

The bacteria and viruses frequently mentioned in the news and public can be disinfected in an average of 30 seconds. When sprayed using the exclusive vaporizers, it is possible to achieve a germ-free condition even in the environment of your home.

Simultaneously, it shows effectiveness in “instantaneous deodorization,” “prevention of molds,” “reduction of pm2.5 (fine particulate air pollution),” “prevention of hay fever,” and “reduction of allergens.”

We are confident of Panacea’s potential as a product that will be widely sought after not only domestically but also in Mainland China, Hong Kong, Taiwan, Singapore, other East Asian countries and even in the global market!


POP


ANTI-BACTERIAL・ANTI-ODOR・ANTI-FUNGAL PANACEA … · Control on irritating odor Non-volatility...

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