Analytical method development by liquid chromatography

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By Prafulla Kumar Sahu

description

Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected drugs from categories like Antihypertensive, Antihyperlipidemic, Skeletal Muscle Relaxant, Non-Steroidal Anti-inflammatory Drug (NSAID), Antibiotic, Anticonvulsant, Antiviral, and Analeptic.

Transcript of Analytical method development by liquid chromatography

Page 2: Analytical method development by liquid chromatography

Development and Validation of Analytical Methods for the Assay of Selected Drugs in Pharmaceutical

Dosage forms and Biological fluids LAP Lambert Academic Publishing ( 2011-10-25 )

Book Details:

ISBN-13: 978-3-8443-2869-1

ISBN-10: 3844328696

EAN: 9783844328691

Book language: English

By (author) :

Prafulla Kumar Sahu M. Mathrusri Annapurna Number of pages: 352

Published at: 2011-10-25

Category: Pharmacy

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Abstract for the book Analytical methods development and validation

play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected drugs from categories like Antihypertensive, Antihyperlipidemic, Skeletal Muscle Relaxant, Non-Steroidal Anti-inflammatory Drug (NSAID), Antibiotic, Anticonvulsant, Antiviral, and Analeptic.

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Analytical Method Development by Liquid Chromatography

Thank You

Development and validation of Analytical Methods for the Assay of drugs in Pharmaceutical dosage forms and Biological fluids