Jonathan Eisen: Phylogenetic approaches to the analysis of genomes and metagenomes
Analysis of metagenomes
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Transcript of Analysis of metagenomes
Analysis of metagenomes
Lars Juhl Jensen
EMBL Heidelberg
the challenge
the sheer amount of data
what can we do with it?
function prediction
sequence homology
gene neighborhood
exploitation
bioremediation
statistical analyses
comparing environments
UndergroundMine Biofilm
SurfaceSea Water
Farm Soil Deep SeaWhale Skeleton
GC content
effective genome size
phylogenetic composition
functional fingerprints
visualization
metabolic reactions
saltmats are like onions …
… they have layers
QuickTime™ and a decompressor
are needed to see this picture.
Acknowledgments
EMBLJeroen Raes
Christian von MeringEoghan Harrington
Konrad FörstnerAmoolya SinghTakuji YamadaIvica Letunic
Peer Bork
JGISusannah TringePhil Hugenholtz
Eddy Rubin