An Introduction to Systematic Reviews
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Transcript of An Introduction to Systematic Reviews
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An Introduction to Systematic Reviews
Shakila ThangaratinamProfessor of Maternal and Perinatal HealthWomen’s Health Research Unit
R & D Director of Women’s HealthBarts Health NHS Trust
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Systematic reviewSystematic review
• What is it?
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Traditional reviews
• Search and acquisition of evidence not clear
• Personal interests of the authors• Reliability issues
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What is a systematic review?
• Systematic undertaking of a review with a focused research question that tries to identify, appraise, select and synthesise all high quality research evidence relevant to that question.
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Systematic reviewsSystematic reviews
• What is it?
• Why do we need it?
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Why do we need Systematic reviews
Why do we need Systematic reviews
• New evidence changes patient management • Delay in implementation can harm patient.• It is difficult to get evidence when it is needed• Knowledge and clinical performance
deteriorates with time without an attempt to keep up-to-date
• Traditional continuing education programs do not improve clinical performance
• EBM keeps its practitioners up-to date
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Why do systematic reviews?
• Support Evidence Based Practice• Research• Inform clinical policy• Publication• Personal professional development
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Systematic reviews
Yes
Good quality reviews
Poor quality reviews
No
Primary studies
Yes
Poor quality study
Good quality study
No
Review of reviews
Conduct Systematic reviews
Design and conduct primary study
Survey of practice
EBM
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Systematic reviewsSystematic reviews
• What is it?
• Why do we need it?
• How to do them?
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How to do systematic reviews?
Formulate clear clinical questions from our knowledge needs
Search the literature to identify relevant articles
Critically appraise the evidence for its validity and usefulness
Synthesise evidence
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Workshop Objectives
• Aim: Familiarisation with Systematic reviews
• Objectives:– Literature Retrieval– Critical Appraisal of:
• Therapy and Diagnosis• Primary studies and Systematic Reviews
– Use of clinically meaningful statistics
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The systematic review process
Formulate research /
policy conclusions
Search bibliographi
c databases
Identify possible papers
from titles/abstracts
Retrieve papers
Extract data
Further selection of
primary studies using inclusion
criteria
Synthesi
s
Formulate
research question
Design search
strategy
Quality
appraisal