An Introduction to Medicinal Chemistry · An Introduction to Medicinal Chemistry Dr. N. SRIDHAR...
Transcript of An Introduction to Medicinal Chemistry · An Introduction to Medicinal Chemistry Dr. N. SRIDHAR...
An Introduction to
Medicinal ChemistryDr. N. SRIDHAR GOUD (PhD, M. Pharm., MBA)Genius Book Record Holder
Postdoctoral Fellow,
Department of Neuroimaging and Interventional Radiology
National Institute of Mental Health & Neuro Sciences (NIMHANS),
Bengaluru-560 029, India.
Email: [email protected]
For Pharma Graduates & GPAT Aspirants
Date: 09/07/2020
Case study:
O Oxa
S Thia
N Aza
P Phospha
O > S > N > P
3 ir (tri)
4 et (tetra)
5 ol (pyrrole)
6 in (pyridine
7 ep (hepta)
8 oc (octa)
9 on (nona)
10 ec (deca)
Ring Size Stem
ane-saturation & e/ene-unsaturation
Rules:
Rule-1: If the last alphabet follows vowel sound, it must be removed
Rule-2: Use the suffix “idine” only fora) Nitrogen containing b) Fully saturatedc) 3, 4 & 5 HCR
Rule-3: Use the suffix “ine” only fora) Nitrogen containing b) Partial saturatedc) 4 & 5 HCR
3-HCR:
4-HCR:
5-HCR:
5-HCR:
Case study:
5-HCR:
5-HCR:
Case study: