An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen...

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An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan, Krupen Patel, Brian A. Hall, Gordon D. Brown, Katherine A. Fitzgerald Cell Host & Microbe Volume 5, Issue 5, Pages 487-497 (May 2009) DOI: 10.1016/j.chom.2009.05.002 Copyright © 2009 Elsevier Inc. Terms and Conditions

Transcript of An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen...

Page 1: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans 

Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan, Krupen Patel, Brian A. Hall, Gordon D. Brown, Katherine A. Fitzgerald  

Cell Host & Microbe Volume 5, Issue 5, Pages 487-497 (May 2009)

DOI: 10.1016/j.chom.2009.05.002

Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 2: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 1

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 3: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 2

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 4: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 3

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 5: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 4

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 6: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 5

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 7: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 6

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 8: An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Figure 7

Cell Host & Microbe 2009 5, 487-497DOI: (10.1016/j.chom.2009.05.002) Copyright © 2009 Elsevier Inc. Terms and Conditions