AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY

MAY 19, 2006

VOLUME 281

NUMBER 20

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PIP3

RTKGab1

Pl3K

LY294002

Gab2

PDK1

PP2A

PAK1

c-Raf

14-3-3

BadXIAP

Bcl-x

CytC

MDM2

FKHR/

FOXO

mTOR

Rictor

Akt

Cyclin D

GSK-3

p21 p27

Pathways In Human CancerImmunofluorescence Using Activation~state Antibodies

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In our Classic Articles you can explore original reprinted articles

dating back to 1905. When completed, this series will contain

over 300 original papers by the legends in biochemistry: including

Folin, Van Slyke, the Coris, Doisy, McCollum, Hastings, Lowry,

Kornberg, Kennedy, Brown, Goldstein, and many more!

JBC Reflections were created as a celebration of JBC’s 100th

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their contributions that have helped mark the many advances in

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Take a journeywith The Journal of Biological Chemistry (JBC) and explore all the exciting and

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Above photograph (by Sam Vandivert, ©The Rockefeller University) shows Stanford Moore (left) and William H. Stein (right) in front of the original amino acid analyzer in 1965.

It is our hope that Classic Articles & Reflections will, in small part, share some of the personal experiences and history of biochemistry.

ReflectionsClassic Articles

A

Adams, David J., 14136

Adriaenssens, Eric, 14307

Akin, Brandy L., 14163

Alam, Rafeul, 14429

Albertsson, Per-Åke, 14241

Alewood, Paul F., 14136

Alfalah, Marwan, 14393

Ali, Arisha, 13949

Altmann, Karl-Heinz, 14192

Ambrose, Christine, 13964

Anderson, Raymond D., III,13865

Antonenko, Yuri N., 14408

Armishaw, Christopher J.,14136

Aro, Eva-Mari, 14241

B

Babu, Geetha, 14041

Bach, Leon A., 14184

Bahr, Claudia, 14224

Balan, Livia, 14151

Bellodi, Cristian, 14465

Bemark, Mats, 13869

Bensadoun, Andre, 13931

Bernassola, Francesca,14465

Bidaux, Gabriel, 14307

Blangy, Stephanie, 14256

Bodmer, Jean-Luc, 13964

Bornhovd, Carsten, 13990

Bossen, Claudia, 13964

Boston-Howes, William,14076

Bourguignon, Lilly Y. W.,14026

Boyer, Thomas G., 14066

Braun, Andrew P., 14015

Brightman, Amy, 14026

Brow, David A., 14119

Brown, Greg, 14514

Brown, Robert H., Jr., 14076

Brunner, Josef, 13999

Bruser, Thomas, 13972

Burdick, Monica M., 13899

Bussen, Wendy, 13861

Butterworth, Michael B.,14129

C

Cabrera, J. Ruben, 14330

Callaghan, Richard, 13906

Callebaut, Isabelle, 13857

Callewaert, Geert, 14144

Cambillau, Christian, 14256

Campanacci, Valerie,14256

Cannon, Barbara, 13882

Castelletti, Deborah, 14393

Cater, Michael A., 14006

Cen, Osman, 14429

Chang, Mikyoung, 14041

Chang, Tong-Shin, 14400

Chang, Tsung-Cheng,14376

Chen, Hao, 13894

Chen, Jian-Zhong, 14192

Chen, Zhenhui, 14163

Chen, Zhi-Hua, 14440

Chu, Julia T., 13899

Chung, Daniel C., 13957

Citri, Ami, 14361

Clark, Gary F., 13853

Cole, Susan P. C., 13906

Connor, Kip M., 14100

Corsico, Betina, 13979

Corthesy, Blaise, 14280

Cossarizza, Andrea, 14465

Cozzone, Alain J., 14048

Craik, David J., 14136

Cramer, William A., 14408

D

Daly, Norelle L., 14136

Daneholt, Bertil, 14263

Danielsson, Ravi, 14241

Dasgupta, Jaya, 14100

Davis, George E., 14015

Davis, Michael J., 14015

Decker, Bridget L., 14523

De Crescenzo, Gregory,14376

de Crombrugghe, Benoit,14417

Deeley, Roger G., 13906

Deen, Peter M. T., 14207

de Groot, Bert L., 14207

Degterev, Alexei, 14474

de Jong, Arjan S., 14144

Dell, Anne, 13853

de Mattia, Fabrizio, 14144

Demont, Yohann, 14307

Deng, Xingming, 14446

Denu, John M., 14057

Detmers, Frank J. M., 14207

de Villartay, Jean-Pierre,13857

Dialynas, George K., 14350

Diedrich, Falko, 14026

Dinsdale, David, 14465

Doering, Christopher B.,13922

Driscoll, Robert, 14321

Duan, Cunming, 14184

Duclos, Bertrand, 14048

Duerr, Eva-Maria, 13957

Dumin, Elena, 14151

Dyson, H. Jane, 14457

E

Eberspaecher, Heidi, 14417

Edinger, Robert S., 14129

Eisenstein, Miriam, 14361

El Yazidi-Belkoura, Ikram,14307

Esumi, Hiroyasu, 13915

Ezekowitz, R. Alan, 14370

F

Faller, Bernard, 14192

Falomir-Lockhart, LisandroJ., 13979

Fischer, Alain, 13857

Flagg, Tammy, 14446

Flitsch, Sabine L., 14207

Flotte, Terence R., 14250

Frizzell, Raymond A., 14129

Fujiki, Kotoyo, 13957

Fuller, Gregory N., 14085

Furuya, Tsuyoshi, 14474

G

Gaide, Olivier, 13964

Gala, Manish, 13957

Gan, Judith, 14361

Gao, Fengqin, 14446

Gao, Ling, 14092

Gehring, Kalle, 14376

Geiduschek, E. Peter,14321

Georgatos, Spyros D.,14350

Geourjon, Christophe,14048

Gertsch, Jurg, 14192

Ghosh, Dipak K., 14173

Gibb, Stuart L., 14076

Gilad, Eli, 14026

Godar, Samuel, 13899

Goldkorn, Tzipora, 14486

Gonzalez, Claudio F.,14514

Gorska, Magdalena M.,14429

Gotting, Christian, 14224

Grangeasse, Christophe,14048

Groover, Olivia, 14376

Grubisha, Olivera, 14057

Grubmuller, Helmut,14207

Gui, Peichun, 14015

H

Ha, Xiao-Fang, 14100

Hamada, Shigeyuki, 14215

Hamon, Jacques, 14192

Handa, Makoto, 14494

Hanein, Dorit, 14383

Harari, Daniel, 14361

Harms, Nellie, 13999

Harris, Elizabeth S., 14383

Harris, Janelle L., 13939

Harris, Jonathan M., 13939

Hattori, Takako, 14417

Hawryluk, Mathew J.,14129

Hecht, Andreas, 14066

Hecht, Sidney M., 13865

Heery, David, 14465

Heidinger, Jill M., 14486

Hertig, Sylvie, 13964

Higgs, Henry N., 14383

Hinton, Andrew, 14207

Hirose, Fumiko, 14232

Ho, Hao H., 14111

Hoeks, Joris, 13882

Holliday, Michael A., 14173

Hondermarck, Hubert,14307

Houben, Edith N. G., 13999

Hu, Limei, 14085

Huang, Changkang, 13894

I

Ikeda, Yasuo, 14494

Ingold, Karine, 13964

Ivashkiv, Lionel B., 14111

J

Jault, Jean-Michel, 14048

Jeong, Woojin, 14400

Jin, Zhaohui, 14446

Jo, Won-Seok, 13957

Johnson, John P., 14129

Jones, Larry R., 14163

Judson, Andrea, 13931

Jun, Sohee, 13869

K

Kahn, Peter C., 13979

Kahyo, Tomoaki, 14417

Kartvelishvily, Elena, 14151

Kassavetis, George A.,14321

Kawabata, Shigetada,14215

Keiser, Markus, 14393

Kendall, Richard L., 13949

Kester, Lauren, 14129

Khan, Elaine M., 14486

Kijas, Amanda W., 13939

Kim, Seokjoong, 14066

Kimchi, Adi, 14361

Kindle, Karin, 14465

Kitamura, Toshio, 14494

Kleesiek, Knut, 14224

Kleino, Anni, 14370

Kleyman, Thomas R.,14129

Kocks, Christine, 14370

Konings, Irene B. M., 14207

Korniyenko, Yurij, 14514

Koteiche, Hanane A.,14273

Kotova, Elena A., 14408

Kourmouli, Niki, 14350

Kozlov, Guennadi, 14376

Kramarova, Tatiana V.,13882

Kroon, Gerard, 14457

Kuehner, Jason N., 14119

Kuhn, Joachim, 14224

L

La Fontaine, Sharon, 14006

Laborde, Lisandro, 13979

Lai, Luhua, 13894

Lavi, Sara, 14361

Lavin, Martin F., 13939

Lee, Duck-Yeon, 14400

Lemoine, Jerome, 14307

Levy, Michal, 14486

Li, Lei, 13869

Liang, Qiaoling, 14429

Lilie, Hauke, 13972

Lim, Chris M., 14006

Lim, Nadia S., 14376

Lindenstrauss, Ute, 13972

Ling, Shizhang, 14015

Lisanti, Michael P., 14486

Liu, Ying, 13894

Lodder, Michiel, 13865

Lofgren, Julie A., 13949

Lohr, Frank, 14503

Lollar, Pete, 13922

Lopez de Saro, Francisco J.,14340

Lu, Jingfang, 14417

Lu, Tao, 14474

Lucke, Christian, 14503

Ludwig, Bernd, 14503

Luirink, Joen, 13999

Luyten, Tomas, 14144

M

MacDonald, Marcy, 14474

Machida, Kiyotaka, 14314

Majewska, Adriana, 14192

Makatsori, Dimitra, 14350

Malivert, Laurent, 13857

Mamedov, Fikret, 14241

Maneg, Oliver, 14503

Manes, Santos, 14330

Marinus, Martin G., 14340

Martinez-Yamout, MariaA., 14457

Matsuno-Yagi, Akemi,14250

Matsushita, Shuhei, 14232

May, W. Stratford, 14446

Mchaourab, Hassane S.,14273

McLean, Kevin, 14350

Melchers, Willem J., 14144

Melendez, J. Andres, 14100

Melford, Kristan, 13931

Melino, Gerry, 14465

Mellstrom, Britt, 14330

Meng, Tzu-Ching, 14100

Mercer, Julian F. B., 14006

Milne, Ginger L., 14092

Mizukami, Yusuke, 13957

Mizushima, Noboru, 14474

Modrich, Paul, 14340

Moineau, Sylvain, 14256

Mori, Hirotada, 14514

Mornon, Jean-Paul, 13857

Morrow, Jason D., 14092

Motojima, Kiyoto, 14232

Mukrasch, Marco D., 14503

Muller, E. Matthias, 14207

The Journal of Biological Chemistry

AUTHOR INDEX

MAY 19, 2006 • VOLUME 281 • NUMBER 20 JOURNAL OF BIOLOGICAL CHEMISTRY ix

Muresanu, Lucia, 14503

N

Naim, Hassan Y., 14393

Nakajima, Hideaki, 14494

Nakamaru-Ogiso, Eiko,14250

Naranjo, Jose R., 14330

Nashchekin, Dmitri, 14263

Nedergaard, Jan, 13882

Nelson, Kristin K., 14100

Neupert, Walter, 13990

Nevin, Simon T., 14136

Niki, Etsuo, 14440

Nishida, Tamotsu, 14417

Noguchi, Noriko, 14440

O

O’Donnell, Mike, 14340

Ogura, Tsutomu, 13915

Ohta, Yoshihiro, 14314

O’Neal, Lindsey E., 13869

Osada, Hiroyuki, 14314

Osumi, Takashi, 14232

Oudega, Bauke, 13999

P

Paakkarinen, Virpi, 14241

Page, Shallee, 13931

Parikka, Mataleena, 14370

Park, Sung Jun, 14400

Parker, Ernest T., 13922

Pasinelli, Piera, 14076

Perraud, Anne-Laure,14057

Perrier, Clementine, 14280

Perry, Clint J., 14129

Peters, Kathryn W., 14129

Petrovic, Natasa, 13882

Pietrokovski, Shmuel,14361

Porter, Ned A., 14092

Prante, Christian, 14224

Preece, Nicholas E., 14457

Pristovsek, Primoz, 14503

Propsting, Marcus J., 14393

Proudfoot, Michael, 14514

R

Raduner, Stefan, 14192

Rafty, Louise A., 14057

Ramakrishnan,Parameswaran, 14361

Ramet, Mika, 14370

Ravid, Tommer, 14486

Raynard, Steven, 13861

Reichert, Andreas S., 13990

Revy, Patrick, 13857

Rhee, Sue Goo, 14400

Rojas, Ana M., 14330

Rothnie, Alice, 13906

Rouiller, Isabelle, 14383

Ruterjans, Heinz, 14503

S

Sackstein, Robert, 13899

Saito, Yoshiro, 14440

Sakaguchi, Yuriko, 14296

Sakurai, Nagisa, 14288

Sale, Julian E., 13869

Salerno, John C., 14173

Salomoni, Paolo, 14465

Sanchez-Pulido, Luis,14330

Savchenko, Alexei V.,14514

Scharenberg, Andrew M.,14057

Schierhorn, Angelika,13972

Schneider, Pascal, 13964

Schon, Sylvia, 14224

Sekine, Azusa, 14440

Seo, Byoung Boo, 14250

Shabalina, Irina G., 13882

Shah, Nirav, 14129

Shen, Xi, 13869

Shibata, Fumi, 14494

Shibata, Mamoru, 14474

Shigi, Naoki, 14296

Shleper, Maria, 14151

Shohat, Galit, 14361

Shuman, Stewart, 13873

Shyu, Ann-Bin, 14376

Siddiqui, Nadeem, 14376

Singh, Prim B., 14350

Singleton, Patrick, 14026

Slomianny, Christian,14307

Smith, Susan M. E., 14173

Sobko, Alexander A.,14408

Sonoda, Eiichiro, 13869

Sormunen, Raija, 14370

Soulat, Didier, 14048

Spinelli, Silvia, 14256

Sprenger, Norbert, 14280

Stafford, Susan J., 14429

Stokes, David L., 14163

Storch, Judith, 13979

Stotz, Stephanie C., 14015

Sturm, Alexander, 13972

Styring, Stenbjorn, 14241

Subbaram, Sita, 14100

Sun, Shao-Cong, 14041

Sung, Patrick, 13861

Suorsa, Marjaana, 14241

Suzuki, Atsushi, 13915

Suzuki, Tsutomu, 14296

Swarts, Herman G., 14144

Sze, Mozes, 14207

T

Takanishi, Christina L.,14057

Tan, Lei, 13894

Tardivel, Aubry, 13964

Tegoni, Mariella, 14256

Terao, Yutaka, 14215

Terjung, Stefan, 14350

Theodoropoulos,Panayiotis A., 14350

Thomas, Clayton, 14173

Tong, Lei, 14057

Tonks, Nicholas K., 14100

Traub, Linton M., 14129

Trotti, Davide, 14076

Tschopp, Jurg, 13964

U

Ullers, Ronald S., 13999

Ulvila, Johanna, 14370

Utsumi, Toshihiko, 14288

V

Valencia, Alfonso, 14330

Vandermoere, Franck,14307

van Dommelen, MichielM., 14144

van Kuppeveld, Frank J.,14144

Venkitakrishnan, Rani P.,14457

Visa, Neus, 14263

Visch, Henk-Jan, 14144

Vogel, Frank, 13990

Volpon, Laurent, 14376

W

Wahl, Robert, 13949

Wallach, David, 14361

Wang, Bixun, 13865

Wang, George K., 14085

Wang, Huamin, 14129

Watanabe, Kimitsuna,14296

Watanabe, Naohide,14494

Waterfield, Michael,14041

Wei, Ping, 13894

Weinberg, J. Brice, 14173

Weixel, Kelly M., 14129

Wickner, William T., 14523

Willems, Peter H., 14144

Williams, Eric O., 14076

Wilson, Emily, 14015

Winkfein, Robert J., 14015

Wolosker, Herman, 14151

Wright, Peter E., 14457

Wu, Xin, 14015

Wu, Xuefeng, 14041

X

Xie, Xiang-Qun, 14192

Xu, Xiaojie, 14057

Xu, Xuan, 14066

Y

Yagi, Takao, 14250

Yakunin, Alexander F.,14514

Yamaguchi, Masaya,14215

Yamaguchi, Tomohiro,14232

Yamane, Harvey, 13949

Yankner, Bruce, 14474

Yarden, Yosef, 14361

Yasuda, Hideyo, 14417

Yin, Huiyong, 14092

Yin, Ping, 14184

Yoshida, Yasukazu,14440

Yoshimori, Tamotsu,14474

Yuan, Junying, 14474

Z

Zakharov, Stanislav D.,14408

Zamponi, Gerald W.,14015

Zhang, Ren, 14417

Zhang, Shiwen, 13949

Zhang, Wei, 14085

Zhang, Xiaobo, 13957

Zhang, Xiaoling, 13949

Zhao, Jian, 14263

Zhao, Yang, 14184

Zhou, Jia, 13865

Zhu, Hui, 13873

x JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME 281 • NUMBER 20 • MAY 19, 2006

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