Aluminum Hydroxide

Magnesium Hydroxide

Saltam

350 mg/ 150 mg/ 5 mL

Oral suspension

Antacid

Formulation

Each 5 m (1 teaspoonful) contains:

Aluminum Hydroxide …….. 350 mg

Magnesium Hydroxide …….. 150 mg

Description of the product

Saltam® Oral Suspension is a mixture containing Aluminum Hydroxide [Al(OH)3] and Magnesium Hydroxide [Mg(OH)2]. It contains the equivalent of not less than 90.0 percent and not more than 110.0 percent of the labeled amounts of Aluminum Hydroxide and Magnesium, Hydroxide

Pharmacology

Aluminum hydroxide slowly reacts with the gastric hydrochloric acid to form soluble aluminium chloride of which is absorbed. On the other hand, Magnesium hydroxide reacts rapidly to form magnesium chloride and water. The presence of food which decreases the gastric emptying rate prolongs the availability of the aluminium hydroxide but shortens that of magnesium hydroxide. 30 to 50 % of the magnesium ions are absorbed in the small intestine. Moreover, about .1 to .5 mg of the aluminium ions are reported to be absorbed which is then eliminated in the urine. The aluminium and magnesium ions remaining in the gastrointestinal tract are excreted in the feces.

Indication

Saltam® Oral Suspesion is given to reduce the constipating effects. The aluminium - magnesium combination is given to patients suffering from hyperacidity.

Contraindication

Saltam® Oral Suspesion should not be given to patients under dialysis due to toxicity. Risk factors form Alzheimer’s disease patients are also significant.

Dosage and Administration

Saltam® Oral Suspesion should be taken orally one hour before taking a meal.

4 to 8 years old …….. 2.5 - 5 ml (one half – 1 teaspoon)

9 to 12 years old …….. 5 – 10 ml (1 – 2 teaspoon)

Adults …….. 10 ml – 20 ml (2- 3 teaspoon)

Precaution

Saltam® Oral Suspesion should be taken with caution to patients with low phosphate diet. It should be taken with caution to patients with renal failure. 2 – 3 hours apart when other medication are taken simultaneously.

Warning

Keep out of reach of children. Shake well before using.

Adverse effects

Saltam® Oral Suspesion may cause nausea, headache and allergic reaction have also occurred. Excessive doses may also cause intestinal obstruction.

Symptoms and treatment of overdose

Inform patients of signs of hypersensitivity and other side effects. Hypermagnesaemia may be experienced in infants and for patients with impaired renal functions. Tetracyclines should not be taken simultaneously with this drug.

Availability

Aluminum Hydroxide – Magnesium Hydroxide tablets, oral 250 mg.

Aluminum Hydroxide – Magnesium Hydroxide tablets, oral 500 mg.

Aluminum Hydroxide – Magnesium Hydroxide oral suspension 250 mg/ 150 mg/ 5 mL

Storage Conditions

Preserve in tight containers and avoid freezing.

Manufacturer and distributor

Date of last chuchu. January 21, 2013