AlcoholAlcohol

Chapter 7Chapter 7

Alcohol and NutritionAlcohol and Nutrition• Public service announcement!Public service announcement!

• Unlike glycerol, ethanol is a drug!Unlike glycerol, ethanol is a drug!

Alcohol in BeveragesAlcohol in Beverages• ModerationModeration

– A drinkA drink– ProofProof

Alcohol in BeveragesAlcohol in Beverages

Alcohol in the BodyAlcohol in the Body

• Alcohol dehydrogenaseAlcohol dehydrogenase• Alcohol: Males vs. femalesAlcohol: Males vs. females

Alcohol in the BodyAlcohol in the Body

Alcohol Arrives Alcohol Arrives in the Liverin the Liver

• AcetaldehydeAcetaldehyde

• Alcohol abuseAlcohol abuse

• NADNAD

Alcohol DisruptsAlcohol Disrupts the Liver the Liver

• Fatty liverFatty liver

http://www.brown.edu/Courses/Digital_Path/Liver/fatty_liver.htm

http://www.brown.edu/Courses/Digital_Path/Liver/fatty_liver.htm

Alcohol DisruptsAlcohol Disrupts the Liver the Liver

• FibrosisFibrosis

• CirrhosisCirrhosis

Alcohol DisruptsAlcohol Disrupts the Liver the Liver

• MEOS = microsomal ethanol-MEOS = microsomal ethanol-oxidizing systemoxidizing system

• Alcohol saturation leads to Alcohol saturation leads to competitive exclusion of other things competitive exclusion of other things like drugs...like drugs...

• Excess whiskey + drugs=drug O.D.Excess whiskey + drugs=drug O.D.

Alcohol Arrives Alcohol Arrives in the Brainin the Brain

• Narcotic effectsNarcotic effects

• Effect on ADH Effect on ADH – depresses activity—you urinate more!depresses activity—you urinate more!– leads to thirst, dehydrationleads to thirst, dehydration– advice, drink two glasses of water before advice, drink two glasses of water before

bed, regardless of what you’ve had (or bed, regardless of what you’ve had (or how much).how much).

kCal in Alcoholic Beverages & Mixers, cont’dkCal in Alcoholic Beverages & Mixers, cont’d

Alcohol’s effects on the BrainAlcohol’s effects on the Brain

Alcohol & MalnutritionAlcohol & Malnutrition• Nutrient displacementNutrient displacement

• Interference with nutrient Interference with nutrient metabolismmetabolism

Alcohol & MalnutritionAlcohol & Malnutrition• AlcoholismAlcoholism

• Wernicke-Korsakoff syndrome-Wernicke-Korsakoff syndrome-– paralysis of eye muscles, impaired paralysis of eye muscles, impaired

muscle movement, etc.muscle movement, etc.– chronic abuse of alcohol leads to B chronic abuse of alcohol leads to B

vitamin deficiency! Oops!vitamin deficiency! Oops!

Alcohol’s Short-Term Alcohol’s Short-Term EffectsEffects

• SuicideSuicide

• HomicideHomicide

• AccidentsAccidents

Alcohol’s Short-Term Alcohol’s Short-Term EffectsEffects

• AssaultAssault

• Sexual assaultSexual assault

Alcohol’s Short-Term Alcohol’s Short-Term EffectsEffects

Alcohol’s Long-Term Alcohol’s Long-Term EffectsEffects

• Alcohol and pregnancyAlcohol and pregnancy

• Heavy alcohol consumptionHeavy alcohol consumption

Alcohol’s Long-Term Alcohol’s Long-Term EffectsEffects

Personal StrategiesPersonal Strategies• Social aspectsSocial aspects

• Consumption strategyConsumption strategy

• MythsMyths