Alchemist TM II: Capacity, reproducibility and efficiency of an high-throughput crystallization...
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Transcript of Alchemist TM II: Capacity, reproducibility and efficiency of an high-throughput crystallization...
AlchemistTM II: Capacity, reproducibility and efficiency of an
high-throughput crystallization screen preparation system.
Craig SterlingDirector of Business Development
Rigaku
CrystalTrakTM
Information Flow & Management
Automated Protein Crystallization Platform
AlchemistTM IIScreen Maker
Minstrel HT & Gallery 700 IncubatorsImaging and Incubation
Phoenix RE ExperimentalPlate Setup
Integration ModuleIncluding Robotic Arm, plate
and block storage, mixing station, piercing station, and
foil and tape sealing
CrystalMationTM Features
AlchemistTM II, Phoenix RE, MinstrelTM HT imaging system and GalleryTM 700 incubators operate independently or as part of the completely integrated CrystalMation system Allows instruments to be added over time to meet budgets Easy and seamless integration
CrystalTrakTM relational database application Easy-to-use design is manageable by tech level personnel Mixing, Piercing & Sealing accessories for CrystalMationTM
system Low cost operation of $10 per plate including maintenance
costs and chemical costs
CrystalTrakTM
CrystalTrak seamlessly integrates the Rigaku Crystallization instruments, offering labs a complete end-to-end solution
Relational database tracks all of the necessary information used in crystallization trials such as chemicals, screens, protein samples, plate type information, images, and annotations
CrystalTrak simplifies and aids in the crystallization process by providing tools that enable users to greatly improve crystallization trial productivity with less user intervention. One-click optimization tools Intuitive screen design tools
CrystalTrak Web offers remote access to data
Custom Screen Maker – The Alchemist II
The best accuracy in the industry for handling stock solutions of all viscosities, dispensing volumes as low as 1µl using the TapperTM
technology
Produce liquid formulations without wasting chemicals during every cleaning, priming and wash cycle
74 Barcoded easy to swap reagents
No tedious setup, cleaning and maintenance
Dedicated syringe for each reagent
Easy screen design with CrystalTrak
NEW Seal-tight BirdFeedersTM
New threaded cap, Seal-tight design Long-term storage of stock solutions on deck Works with standard stock solution bottles
Barcode Tracking of birdfeeders and stock solutions Autoclave-able design Easy-pour design for replacement of stocks Four different stock solution sizes
20ml in Birdfeeder with cap Good for expensive stocks and additives
125ml Nalgene bottles 250ml Nalgene bottles
Three Syringe sizes (Eppendorf) 100ul 1ml 10ml
CrystalTrakTM
Information Flow & Management
Automated Protein Crystallization Platform
AlchemistTM IIScreen Maker
Minstrel HT & Gallery 700 IncubatorsImaging and Incubation
Phoenix RE ExperimentalPlate Setup
Integration ModuleIncluding Robotic Arm, plate
and block storage, mixing station, piercing station, and
foil and tape sealing