Agri-Business Incubation Centercifa.nic.in/sites/default/files/Commercialisation of...

Agri-Business Incubation Center ICAR-Central Institute of Freshwater Aquaculture

(Indian Council of Agricultural Research)

P.O. Kausalyaganga: Bhubaneswar –751 002

Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407

e.mail, [email protected] Web site: http://www.cifa.in

TECHNOLOGY TRANSFER / COMMERCIALIZATION OF ICAR- CIFA

TECHNOLOGY THROUGH INDUSTRIES/ ENTREPRENEURS

ICAR-Central Institute of Freshwater Aquaculture, Kausalyagnaga, Bhubaneswar, Ministry of

Agriculture, Government of India, is interested in technology transfer/ commercialization on

non-exclusive basis through Industries/ Entrepreneurs in respect of following technology/

design developed by the institute on terms & conditions as given below.

Name of the Technology/Design

A. Diagnostic KITs

I. Spot agglutination Kits for diagnostic of Bacterial gill disease in fish

II. Dot Elisa Kits for diagnostic of Bacterial gill disease, columnaris disease in fish

B. Immuno diagnostic Aids

I. Rohu Catla Hybrid Detection Kit

II. Argulus (A. siamensis & A. japonicas) Detection Kit

III. White Tail Disease Diagnostic Kit

IV. Koi Herpes Virus (KHV) Diagnostic Kit

V. Spring Viraemia of Carp Diagnostic Kit

C. Aquaculture Applications

I. FRP Demand Fish Feeder

Firms/entrepreneurs interested in the technology/design listed above are requested to fill the

Expression of Interest (EOI) as per the format given in Annexure 1 and send their documents

complete in all respect along with processing fee of Rs 1000/- in favor of “I.C.A.R. Unit,

CIFA” payable at Bhubaneswar to the following address:

The Director

ICAR - CENTRAL INSTITUTE OF FRESHWATER AQUACULTURE,

(ISO 9001:2008 Certified) Kausalyagnaga, Bhubaneswar– 751 002, Odisha, India

Phone: 0674-2465421, Fax: 0674-2465407 Web : http://www.cifa.nic.in




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


Objectives of Commercialization:

Technology leaflet attached for each technology.

Terms and Conditions for application

1. The industry willing to take the technology shall be required to enter into a Memorandum of

Understanding (MoU) with ICAR-Central Institute of Freshwater Aquaculture,

Bhubaneswar, Odisha in the prescribed format, as per the terms and conditions approved by

the competent authority.

2. An expert committee will scrutinize the applications for follow-up action. Shortlisted

agencies/individuals will be called for a presentation regarding their strengths and business

proposals.

3. Technical Commercial Committee (TCC) formed for the purpose reserves the right of

rejecting any offer without assigning reasons.

4. A pre-commercialization meeting will be held at ABI-CIFA, Bhubaneswar as per request of

the applicant in order to appraise regarding this technology, anticipated volume of business

and any queries raised by the applicants. The parties should attend the meeting at their own

cost.

5. The Agency should have/ will procure all necessary approval from different departments for

manufacturing or establishing the said technology.

6. Intellectual Property Right (IPR) will remain with ICAR, New Delhi.

7. Technologies commercialization process is handled by ABI and detailed business plans are

available to the potential entrepreneurs for establishment of the technology based business

enterprises.

8. Information relating to the commercialization along with technology brief of the eight

technologies will be available in the ICAR-CIFA website round the year.

9. The cost of the technology to be paid to ICAR-CIFA will be charged per technology per

year basis.

10. The entrepreneurs/farmers/government departments will be encouraged to take technology

for 3-7 years period. Minimum period will be necessarily 3 years.

11. All eight technologies will be commercialized in a non-exclusive basis. However exclusivity

may be given for a particular zone with predefined terms and conditions.




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


12. There will be Four zones of exclusivity:

Zone-1 (Northern zone): J&K, Punjab, Uttar Pradesh, Uttarakhand, Rajasthan, Delhi, Haryana

and Himachal Pradesh

Zone-2 (eastern and Northeastern Zone): North East States (8), Odisha, West Bengal and Bihar.

Zone-3 (Central and Western Zone); Madhya Pradesh, Chhattisgarh, Jharkhand, Gujarat, Goa

and Maharashtra

Zone-4 (Southern Zone): Karnataka, Kerala, Tamil Nadu, Andhra Pradesh and Telangana

13. Each interested party would take up any zone with maximum of two zones.

14. In the zone where private person has taken the technology, there shall be a locking period of

two years in which no other private parties will be given the technology. Based on the

performance of the first party in each zone, the second party will be created only after two

years.

15. However, in the same zone the government agencies will be allowed to take the technology

irrespective of the presence of private partners.

16. The cost of diagnostics can be reduced by clubbing multiple technologies as recommended

in earlier meetings. Hence, the commercial partners will be encouraged to undertake

multiple numbers of diagnostic technologies to make diagnostic centers more commercially

viable.

17. Applicant may choose induction by ABI-CIFA as Incubatee for a period of two years from

Signing of MoU.

18. Along with the technology (like control, protocol, methods etc), the inventor scientist will

also extent handholding support for the period of 6 months to establish laboratories and

business enterprises.

19. Any dispute, controversy or claim arising out of or in relation to the MoU, or the breach,

termination or invalidity thereof, shall be settled amicably by negotiation between the

Parties. In case of failure of negotiations an arbitrator will be appointed by Director-General,

Indian Council of Agricultural Research (ICAR), New Delhi. The decision of ICAR shall be

final and binding. Jurisdiction for settlement of any dispute under this agreement will be

Bhubaneswar.

Who should apply

Interested parties with credible experience, knowledge & technical capability are encouraged to

apply.




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


Important Dates:-

Submission of EoI- Open round the year

Technical presentation/ discussion by innovators:- within 5 days of Submission of EoI

Issue of Acceptance letter- 7 days of Submission of EoI

Signing MoU –After receiving full payment and within 7 days of Issue of Acceptance

letter

Transfer of Technology including protocols, business plans, training, literature, control

etc- 90 days of signing of MoU.

For detailed information of design/ technology, please see Technology Leaflet attached.

For more information please visit our website: www.cifa.nic.in

For further enquiries, please contact:

The Director

ICAR - CENTRAL INSTITUTE OF

FRESHWATER AQUACULTURE,

(ISO 9001:2008 Certified) Kausalyagnaga,

Bhubaneswar– 751 002, Odisha, India

Phone: 0674-2465421, Fax: 0674-2465407 Web

: http://www.cifa.nic.in

The Principal Investigator,

Agribusiness Incubation Center (ABI)

ICAR - CENTRAL INSTITUTE OF

FRESHWATER AQUACULTURE,

(ISO 9001:2008 Certified) Kausalyagnaga,

Bhubaneswar– 751 002, Odisha, India

[email protected]




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


Annexure I

Proforma for submitting the Expression of Interest

1. Name of the Technology applied for

2. Name of the firm/organization/company and

nationality with all contact details

3. Details of registration as an industry/ legal entity

(copy of certificate to be attached)

4. State full names and addresses of persons having

direct financial interest (applicable for

proprietary and partnership firm)

5. Details of the manufacturing experience,

qualifications, technical capabilities and

expertise of the party to show that it can handle

the following parameters;

1.

2.

3.

6. Production capacity, plan & space available for

the proposed production work

7. Financial background with a latest copy of

audited annual report attached

8. List of major customers

9. ISO certification, if any

10. Initial technology transfer fee, the party proposes

to pay

11. Any other information to substitute technical and

financial competence of the party




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


(Separate sheets may be enclosed if the space provided is insufficient; Application with

incorrect and incomplete information will not be considered)

I/We request that I/We may be considered for granting technical know-how for

……………………………………………………...(technology).

I/We assure that all the information provided by me/us on this form is true to best of my/our

knowledge, and on the basis of this information any decision taken by ICAR- Central Institute

in Freshwater Aquaculture shall be accepted by me/us. I/We also undertake to furnish any

further information required in this connection.

Please find enclosed a Demand Draft (non-refundable)/ Bankers Cheque

No.______________________ dated ______________ of Rs1000/- drawn in favor of ICAR

UNIT-CIFA, Payable at Bhubaneswar, as application processing fee.

1. Application processing fee: Rs. 1000/- for Indian entities

2. Duly filled EOI application must be enclosed with the Demand draft/ banker’s cheque for

application processing fee drawn in favour of ''ICAR UNIT-CIFA'', Payable at Bhubaneswar,

and must be sent to the Institute's address.

………………………….

Signature of the Applicant

Complete Postal address

………………………………

…..…………………………..

………………………..……..

………………………………

Technology Leaflets

Attached separately




Tel. Nos. +91-9438381516, 9439923689 FAX: 91-674-2465407


EXPRESSION OF INTEREST

No. 1/1/2017

COMMERCIALIZATION OF 'EIGHT TECHNOLOGIES THROUGH INDUSTRIES/ ENTREPRENEURS

The ICAR-Central Institute of Freshwater Aquaculture (CIFA), Kausalyaganga, Bhubaneswar, Odisha, 751002, has developed eight commercialisable technologies.

A. Diagnostic KITs I. Spot agglutination Kits for diagnostic of Bacterial gill disease in fish

II. Dot Elisa Kits for diagnostic of Bacterial gill disease, columnaris disease in fish

B. Immuno diagnostic Aids i. Rohu Catla Hybrid Detection Kit

ii. Argulus (A. siamensis & A. japonicas) Detection Kit iii. White Tail Disease Diagnostic Kit iv. Koi Herpes Virus (KHV) Diagnostic Kit v. Spring Viraemia of Carp Diagnostic Kit

C. Aquaculture Applications

i. FRP Demand Fish Feeder

These technologies have received appreciation from different stakeholders in widely tested field trials. To promote localized production/ manufacture to ensure the availability of this technology to the farming community, Expression of Interest (EOI) is invited from firms/ agencies/ entrepreneurs interested in commercial manufacture of this technology. The licensing will be on non-exclusive basis for a period of 3 years, with one-time payment of license fee (as indicated in each technology Leaflet) besides service tax at the prevailing rate is applicable to the license fee. Interested firms/ agencies/ entrepreneurs may also submit a brief profile of their activity, turn-over and a copy of audited financial statement of the last three years, along with a non-refundable demand draft of Rs. 1000/- drawn in favour of ICAR-CIFA, payable at Bhubaneswar towards participation fee. The EOI should be sent in a sealed envelope addressed to The Director, ICAR-Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar-751002, Odisha, India Phone: 91-674-2465421, 2465446 FAX: 91-674-2465407 e-Mail: [email protected], Website: www.cifa.nic.in superscribing 'EOI for technology commercialization”.

Principal Investigator, ABI-CIFA

http://www.cifa.nic.in/

Rohu Catla Hybrid Detection Kit Inventor Scientists: P. Jayasankar, M. Mohanty, L. Sahoo, P. Das, B.K. Das, P. Routray and D.K. Varma

A PCR based identification kit has been developed which can identify hybrid in just two steps with

genomic DNA as starting material. This is a specific kit designed for the identification of Labeo rohita (Rohu),

Catla catla (Catla) and their Hybrid in the early life stages. This technology would really be of great use for

those producers and buyers for screening of quality seeds and moreover it would be a stepping stone for

seed certification programs for both government and private hatcheries.

BENEFITS •PCR and agarose gel based detection kit •Highly specific for rohu catla hybrids in reciprocal crosses •Ensure purity of seed •Potential for seed certification •No sequencing is required •Detection can be done easily in an agarose gel •Less time consuming process, 4-6 hours

Business Opportunity This technology will be of great use in the seed certification programme and will also be beneficial to the farmers for quality and pure seed culture. A state or regional level Diagnostic Center can be established by public organization and private entrepreneurs. ICAR-CIFA will provide training, handholding support and control to run this technology.

Contact: Dr. P. Jayasankar, Director

ICAR-Central Institute of Freshwater Aquaculture (Indian Council of Agricultural Research)

Kausalyaganga, Bhubaneswar-751002, India 0674-2465407, 2465446 e-mail:

[email protected] web: www.cifa.in

Physical Requirements Financial Requirements

Sample Test (in nos.) 2,000 Machinery and Equipment 6.15

Shed & Building 10'x15' Working Capital (in Lakhs) 4.29

Manpower Required Turnover (in Lakhs) 13.05

Supervisor 01 no. Net Profit (in Lakhs) 3.40

Skilled Worker 01 no. IRR 23%

Unskilled Worker 01 no. DSCR 1.17

Technology Cost Rs. 43,112/- per Year

ICAR-CIFA Technology for Commercialization

Dr. N.K. Barik, PI-ABI-CIFA ICAR-Central Institute of Freshwater Aquaculture

(Indian Council of Agricultural Research) Kausalyaganga, Bhubaneswar-751002, India Mob: 9438381516/ 9439923689 e- mail:


tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

mailto:[email protected]

FRP Demand Fish Feeder Inventor Scientists : B. C. Mohapatra, B. Sarkar, S. K. Singh, D. Majhi & N. Sarangi

FRP demand fish feeder has main components of 10 liter capacity feed hopper and activated mechanism. The feeder is installed in a pond with the activating mechanism extending into the water through an activator rod. The feed drops by gravity onto the adjustable acrylic feed platform positioned below the hopper and above the water level. When fish activates the rod, feed pellets retained on the feed platform slowly drop on to the water surface.

Benefits •It is easy to construct, low cost and maintenance free. •The feeder is suitable for pelleted fed and can be used in any kind of rearing system. •The growth rates of fish were estimated 10-15% higher in the demand feeding cisterns / tanks fitted with feeders than the hand feeding tanks. •The demand feeders will increase feed consumption in fish by making it available to them continuously. •The designed feeder can hold 10 kg feed, which is sufficient to feed 500 kg fish if fed @ 2% of their body weight per day. •By reducing the feed quantity to the pond, the organic pollution will be less in the feeder fitted pond.

Business Opportunity This technology will be of great

use in reducing labour and also

will be beneficial to the farmers

by increasing efficiency of feed

distribution. A state of the art

manufacturing facility will be

required by the entrepreneurs.

ICAR-CIFA will provide training,

handholding support and

control to run this technology.

Physical Milestone Financial Milestone

Feeder Sell(in nos.) 200 Machinery and Equipment 1.25


Turnover (in Lakhs) 31.67

Manpower Required Net Profit (in Lakhs) 5.42



Technology Cost Rs. 60,144/-









tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


Argulus (A. siamensis & A. japonicus) Detection Kit Inventor Scientists : P. K. Sahoo & Team

In Indian aquaculture, Argulosis caused by Argulus sp., predominantly A. siamensis and A. japonicus, is one of the most devastating and economically important disease of freshwater culture system. A loss to the tune of Rs.300 crore per annum has been estimated due to this disease in India. Rapid detection and identification of this pathogen is of paramount significance for timely implementation of effective counter measures. Argulosis management measures should be species-specific for far-reaching results because both species of Argulus demonstrate differences in infection and pathology patterns. The Argulus Detection Kit utilizes the polymerase chain reaction as the method in species-specific identification of the two important Argulus sp., A. siamensis and A. japonicus.

Benifits •Ready to use •Results comes within 8 hours only • Greater accuracy compared to microscopic identification •Quality assurance provided by controls •DNA fragment of both species

Business Opportunity

This technology will be of great use

in detection of Argulus sp. and also

will be economically beneficial to

the farmers. A state or regional

level Diagnostic Center can be

established by public organization

and/or private entrepreneurs.


handholding support and control

to run this technology.

















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


White Tail Disease Diagnostic Kit Inventor Scientists: P. K. Sahoo & Team

White Tail Disease (WTD) or White Muscle Disease (WMD) has caused mass mortality in larval and

early juvenile stages as well as devastating production loss in culture systems of Macrobrachium rosenbergii

(scampi) in many countries, particularly India, China, Thailand and Taiwan. Recently, it has been reported

from Australia also.

Benefits •Significantly reduce the risk of crop failure. •Conventional diagnostics fails to detect early stages of infection, hence developing a genome based detection system of this M rogenbergii nodavirus, the causative agent of WTD is essential •This kit based on nested PCR method for RNA segment II is a sensitive and specific diagnostic tool that can detect carriers and early or latent infections. •Detects up to four virus particles. •Follows nested PCR principles – High sensitivity & specificity of virus detection. •The entire procedure can be completed within a day.

Business Opportunity This technology will be of great use

in detection of WTD and also will

be economically beneficial to the

farmers. A state or regional level

Diagnostic Center can be


and/or private entrepreneurs.




















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


Koi Herpes Virus (KHV) Diagnostic Kit Inventor Scientists : P. K. Sahoo & Team

The koi herpes virus is also known as cyprinid herpes virus 3 (CyHV3), belonging to the family Alloherpesviridae and widely

distributed in different geographical regions around the globe. The outbreak of the virus causes mass mortality among

populations of koi Cyprinus carpio koi and common carp Cyprinus carpio carpio, with clinical signs such as swelling and necrosis of

gill filaments, sunken eyes and excessive mucous production leading to discolouration of skin. The ready to use PCR kit contains

the components for polymerase chain reaction that allows rapid amplification of KHV DNA using the gene specific primers. The

nested pcr kit can detect up to single virus particle in tissues. This kit can be used in disease surveillance, developing control

measures and detection of virus in hatcheries and farms.

Benefits •Ready to use •Time saving and cost effective •Easy and rapid protocol •Can be completed within 7 hours •Highly specific and sensitive •Nested PCR can detect even up to single purified virus particle •The primers can also be used in real time PCR

Business Opportunity This technology will be of great use in detection of Koi Herpes Virus and also will be economically beneficial to the farmers. A state or regional level Diagnostic Center can be established by public organization and/or private entrepreneurs. ICAR-CIFA will provide training, handholding support and control to run this technology.

















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


Spring Viraemia of Carp Diagnostic Kit Inventor Scientists : P. K. Sahoo & Team

The spring viraemia of carp (SVC) is a fatal rhabdovirus infection in several carp and ictalurid fish species capable of causing an acute haemorrhagic and contagious viraemia that mainly attack the kidney, gill, spleen and encephalon. The causative pathogen is a single, non segmented RNA virus responsible for huge economic losses in various countries. For easy detection of pathogen, the CIFA developed nested RT-PCR based diagnostic kit is found to be advantageous for rapid and sensitive detection of the virus in fish. This PCR based approach can be used for routine diagnosis of the disease in field and laboratory conditions. This kit can be used in disease surveillance, developing control measures and detection of virus in hatcheries and farms. The primers provided have also been checked in real time PCR to increase the sensitivity of the kit as well as to quantify viral particles in infected tissues.

Benefits •Ready to use •Time saving and cost effective •Easy and rapid protocol •Can be completed within 7 hours •Highly specific and sensitive •Nested PCR can detect even up to single purified virus particle •The primers can also be used in real time PCR

Business Opportunity This technology will be of great use in detection of Spring Viremia and also will be economically beneficial to the farmers. A state or regional level Diagnostic Center can be established by public organization and/or private entrepreneurs. ICAR-CIFA will provide training, handholding support and control to run this technology.

















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


Dot-ELISA Kit Inventor Scientist : P. Swain

‘Dot-ELISA kit’ is used for diagnosis of Edwardsiellosis, Aeromoniasis and Bacterial gill disease of carps.

Benefits It detects the bacterial antigens of Aeromonas hydrophila, Edwardsiella tarda, Pseudomonas fluorescens and Flavobacterium branchiophilum in infected tissues upto 72 hours of death and antibodies in serum for disease diagnosis and routine health monitoring of fish stock. It is suitable for farm site and laboratory use as well as health certification by diagnostic laboratories.

Business Opportunity This technology will be of great use in detection of bacterial antigens and will be beneficial to the farmers for quality and pure fish culture. A state or regional level Diagnostic Center can be established by public organization and/or private entrepreneurs. ICAR-CIFA will provide training, handholding support and control to run this technology.


Kit Sell (in nos.) 1000 Machinery and Equipment 2.30















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


Spot Agglutination Kit Inventor Scientist : P. Swain

Spot agglutination kit is an on farm quick diagnostic test, which detects the above bacterial diseases

of fish such as Aeromoniasis, Edwardsiellosis, Pseudomoniasis and Bacterial gill disease in few seconds. It

may be used by carp hatcheries and fish farmers to screen these specific diseases.

Benefits •Fast method for disease detection and 30-40 samples can be tested within an hour. •Easy to be used by common fish farmers. •Very cheap, to be used by an ordinary fish farmers. •Suitable for farm level diagnosis. •Can be procured by any common fish farmer

Business Opportunity This technology will be of great use

in the seed certification program

and also will be beneficial to the

farmers for quality and pure seed

culture. A state or regional level

Diagnostic Center can be


and private entrepreneurs. ICAR-

CIFA will provide training,




Kit Sell (in nos.) 2000 Machinery and Equipment 2.50















tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407

tel:91-2465421,2465446, Fax:91-674-2465407


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