Affidavit of Bryan a. Krumm RN 8-16-00
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It has been shown that
different cannabinoids act synergistically to produce greater therapeutic effect
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than single cannabinoid therapy. When the
receptor agonist, palmitoylethanolamide,
they produce an analgesic effect one hundred times greater than either
substance when administered by itself (22).The reason for this synergistic effect is that the human body contains different
types of cannabinoid receptors, which react differently to different cannabinoids,
and are involved in different aspects of the disease process. For instance, THC
It has also been shown that
the use of cannabinoids, such as those found in marijuana, may be effective in
treating many of those diseases
Rd, Edgewood, NM 87015,(505) 286-1325.
am working with New Mexicans for
Compassionate Use to end the damage caused to our society by the war on
drugs. I am recognized by the New Mexico court system as an expert on the
medical uses of marijuana and the history of medical marijuana. I have been
studying the history, effects, and uses of marijuana for over 15 years. I am the
chief researcher for the Cannabis Research Library, the largest online collection
of cannabis research in the world
I use marijuana for the treatment of depression and knee pain, and my
primary care physician has referred me to the Lynn Pierson Therapeutic
Research Program. This program was established under the Controlled
Substances Therapeutic Research Act in 1978, and allows the medical use of
marijuana in New Mexico. Under this program, research was conducted which
proved the safety and efficacy of smoked marijuana for the treatment of multiple
sclerosis and for treating the nausea and vomiting associated with cancer
chemotherapy. Unfortunately, the unreasonable, arbitrary and capricious actions
of the US government led to closure of the program when they refused toapprove further research protocols and then cut off our supply of marijuana
entirely. Therefore, I have three choices. I can turn to an unreliable and
dangerous black market. I can risk losing everything I have by cultivating my
own medicine_ Or, I can go without a needed medication that has unique
pharmacological properties, which can not be mimicked by any other known
class of drug.
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The human body contains a complex system of cannabinoid receptors and
produces its own cannabinoids
forming an endogenous cannabinoid
system that is involved in normal homeostasis of the immune system
transmission of pain responses
am 37 years old. I am a registered nurse at the University of
New Mexico Mental Health Center and
It
has been shown that dysfunction of the endogenous cannabinoid system is
involved in certain disease states
receptor agonist, anandamide,
is given at the same time as the
Affidavit of Bryan A. Krumm RN
My name is Bryan Alan Krurnm.
live at 17
perception, and mood
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is available legally in the United States as a Schedule III drug. THC is a strong
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receptor agonist but has minimal activity at the CB2 receptor and may
actually act as an antagonist at the CB2 receptor (14). CB2 receptor agonists
may prove to be an important class of medications for the treatment of
autoimmune diseases (7, 24) and are found in whole marijuana but not in THCcapsules.
Cannabinoids have been shown to protect the brain against damage from
stroke and trauma
and may protect against neurodegenerative
disorders such as alzheimers and multiple sclerosis (26, 27, 28). Cannabinoids
may also protect against certain types of cancer (29) and have been shown to
inhibit proliferation of certain types of tumor cells
31, 32) and reduce tumor
size. (31) They are effective in treating various movement disorders (33, 34, 35,
36) and hold potential for treatment of various psychiatric disorders (37, 38, 39,40).
Marijuana is far safer than most medications available to us. Inquiries into
the health effects of cannabis has found it to be an incredibly safe drug (41). In
over 5,000 years of use, there has never been a recorded fatal overdose. An
individual would have to smoke over a thousand high potency cannabis
cigarettes in order to have a toxic reaction, making it impossible to have a fatal
overdose (42). The low density of receptors in
nuclei is consistent with
the lack of lethal effects in humans (43). The studies on chronic marijuana use
that have been conducted suggest that tolerance rapidly develops to many of the
effects of cannabis use and field studies have failed to find any major
consequences from chronic heavy use of cannabis (44). No clinical evidence
has been discovered suggesting increased prevalence of opportunistic infection
or malignancy among cannabis users (45). A study of 65,171 individuals found
that marijuana use has little effect in non-AIDS mortality in men and total
mortality in women. The effect on AIDS related mortality in men was probably
not causal but rather represented an uncontrolled confounding factor associated
with male homosexual behavior (46).
Although the federal government is aware of the therapeutic potential ofmarijuana, they have routinely suppressed scientific findings. For example, a
two-year study of THC was conducted on rats and mice that found THC treated
animals had significantly lower rates of many types of cancer. This report was
shelved for over two years until a copy was leaked to AIDS Treatment News,
stamped on every page NOT FOR DISTRIBUTION OR ATTRIBUTION (47).
Health and Human Services quickly made a version available to the public after
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being confronted with the leaked copy (29).
Another example is the 1997 NIH Workshop on the Medical Utility of
Marijuana. The transcripts from the workshop show that the panel of experts
agreed marijuana has medical value (48). It was even found that the evidence
is perfectly clear that smoking is an outstanding route of administration...& a
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very safe drug and therefore it would be perfectly safe medically to let the patient
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determine their own dose through the smoking route (ibid
The
Executive Summary that was issued to the public by NIH was far less
enthusiastic than the group of experts. It recommended further research and no
smoking (49).
This comes as little surprise. For over a century, every serious scientific
inquiry into the effects of marijuana have found it to be an incredibly safe drug
that causes little harm to society. It has routinely been found that marijuana
prohibition, causes more harm to society than marijuana use (41). The US
Government has routinely ignored science, as well as the will of The People,
who have passed medical marijuana measures. They continue to persecute all
marijuana users, including those who need its important healing properties. After
all, marijuana prohibition is founded in racism and intolerance, not science. At a
luncheon, October
Director of the Office of National Drug Control Policy, why he
still supports persecuting medical marijuana users such as myself. I pointed out
that the report he commissioned from the Institute of Medicine recommended
allowing smoked marijuana for medical use under certain circumstances (50).
He responded to a room full of people that the report was available on his web
site and that it did not recommend smoked marijuana under any circumstances.
Then he called medical marijuana a crock.
When the Mexican American War was ended by the Treaty of Guadalupe
Hidalgo, it did not end the hostile feelings many Americans harbored towards
Mexicans. As Mexicans immigrated to the western states and took scarce jobs,
it created more tension. These immigrants also brought their cultural and
religious traditions, one of which was the use of marijuana for medical,
religious, and recreational purposes.
Within the traditions of Curanderismo, marijuana is called La Santa Rosa, or
the sacred rose. It is used as part of a religious healing ceremony and is
considered to be a piece of the heart of God
marijuana laws in 1929, the Montana Legislature, described such a ceremony as
an imaginary bullfight for the favor of Spanish Rose and went on to say itdeplores these international complications (53).
When passing early marijuana laws, numerous state legislatures described
marijuana as a drug that causes Mexicans to go insane
City Editor of The Alamosa Daily Courier of Alamosa, Colorado, which was read
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into the record of the hearings on the 1937 Marihuana Tax Act (the first federal
law regulating marijuana) by Harry J. Anslinger, Commissioner of the Federal
Bureau of Narcotics. This letter stated in part:
I wish I could show you what a small marihuana cigarette can do to
The attitudes and
intent of the people of Colorado are illustrated in a letter from Floyd K.
in Albuquerque, I had the opportunity to ask General
Barry
When passing its first
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abiding citizens.
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Prohibition serves to protect the financial interests of industries that would
have to compete with marijuana in a free market. It assures the financial
success of those responsible for waging this war on the American People. It
strips us of our inalienable rights to life, liberty, and the pursuit of happiness. I
live in fear that a small army of masked gunmen may come bursting through my
door at 3 am and shoot me in the back while Im lying in bed, simply for being a
medical marijuana user. In view of the number of deaths by drug warrior our
society has suffered, its a very real fear for medical marijuana patients living in
the United States.
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came to testify for the AMA testifying that, The American Medical Association
knows of no evidence that marihuana is a dangerous drug. One of theCongressmen said in response, Doctor, if you cant say something good about
what we are trying to do, why dont you go home? The next Congressman said,
Doctor, if you havent got something better to say than that, we are sick of
hearing you. (55)
Early marijuana laws were intended not only to oppress Mexican immigrants,
but to prevent them from the free practice of religion. Today these laws not only
prevent millions of Americans from freely practicing religion but millions more
suffer from lack of needed medication under these oppressive policies. Millions
of others have suffered the severe legal and social consequences associated
with being arrested for marijuana use. There is no scientific rationale to justify
the
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one of our degenerate Spanish-speaking residents. Thats
why our problem is so great; the greatest percentage of our
population is composed of Spanish-speaking persons, most of
who are low mentally, because of social and racial conditions (54).
While this was considered in passing federal anti-marijuana legislation, the
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opinion of the American Medical Association was ignored. Dr. William
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Affidavit of Bryan Alan Krumm
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Signed this
2000
Subscribed and sworn to before me this 16th day of August, 2000 by Bryan
Alan Krumm.
day of