Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of...

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Adrenal Medulla. Prof. K. Sivapalan

Transcript of Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of...

Page 1: Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of adrenal gland and paravertibral ganglia. Blood supply -

Adrenal Medulla.

Prof. K. Sivapalan

Page 2: Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of adrenal gland and paravertibral ganglia. Blood supply -

08-01-14 Adrenal Medulla. 2

Strtucture.

• Location- centre of adrenal gland and paravertibral ganglia.

• Blood supply - cortical- sinusoids into medulla and some arterioles.

• Nerve supply- pre ganglionic sympathetics.

Page 3: Adrenal Medulla. Prof. K. Sivapalan. 08-01-14Adrenal Medulla.2 Strtucture. Location- centre of adrenal gland and paravertibral ganglia. Blood supply -

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Effects of Catecholamines• glycogenolysis- liver,muscle.• gluconeogenisis.• lipolysis- adipose tissue.• potassium- release increased in liver

[initial rise], entry increased in muscle [prolonged fall].

• increases- metabolic rate, calorie genesis, alertness, anxiety, fear.

• reduces- proteolysis in muscle, insulin secretion.

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Differences.

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Regulation of Secretion.

• Sympathetic activity.• Sleep:- very low.• Rest:- less• Increased in: hypoxia, asphyxia,

acidaemia, hypoglycaemia, hypothermia, hypotension, haemorrhage, exercise, fear, anger, pain, sexual excitement.

• Stress:- maximum.