ACIS ® III Image Analysis Robert Carlson Manager, Imaging Systems *Accurate *Efficient *Consistent...

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ACIS ACIS ® ® III III Image Analysis Image Analysis Robert Carlson Manager, Imaging Systems *Accurate *Efficient *Consistent *Easy to use

Transcript of ACIS ® III Image Analysis Robert Carlson Manager, Imaging Systems *Accurate *Efficient *Consistent...

ACISACIS®® III IIIImage AnalysisImage Analysis

Robert Carlson

Manager, Imaging Systems

*Accurate *Efficient *Consistent

*Easy to use

DAKO: 40 Years Experience in AP MarketplaceFrom Antibodies to System Solutions

1966 Antibody Production

1995 TechMate™

2000 Dako Autostainer™

2002 Artisan™

2006 ACIS® III

2007 The Dako Link Solution

Addressing Your Challenges

Cost and Productivity Turn Around Time Quality

Utilize labor time more efficiently

Simplify ordering processes

Streamline workflow

Eliminate redundant tasks

Process simultaneously

Reduce repeats

Improve consistency

Implement cutting-edge technologies

ACISACIS®® III is Accurate III is Accurate

Proprietary, color-based image analysis software combined with Whole Slide Scanning automated microscopy

FDA Cleared Applications

HercepTestTM for HER2

ER

PR

Additional applications

Generic applications (Membrane, Nuclear, Microvessel Density, Ploidy, Rare Event)

Tissue Micro Array (TMA)

Flexible solutions to meet unique research needs

ACISACIS®® III is Efficient III is Efficient

Technician Operation

Automated calibration (10 min., once every 24 hours)

Accessioning

Dako LINK software Integration

ACIS III accessioning screen

Automated processing of slides

High capacity (100 slides)

Continuous access 24 hours a day

Immediate access to digital slides for scoring

Analysis of digital slides by pathologist

Need a quick consult or second opinion…use Dako EyeShareTM

Report generation by pathologist or technician

ACISACIS®® III is Consistent III is Consistent

Gold Standard Calibration

Daily, one-touch calibration ensures proper focus, color balance and light intensity

Calibration does not require additional pathologist time

ACIS III improves inter-observer reproducibility with consistent stain intensity scoring

Proper calibration helps ensure laboratory results are consistent

4-tab Dako software format

Accessioning

Microscope

Analysis

Report

Easy to use

Reduces training time

Reduces hands-on time

ACISACIS®® III is Easy to use III is Easy to useSoftwareSoftware

Dako EyeShareDako EyeShare™™

Remote Slide Viewing Software via the internet

Live Consultation

Second opinions

Teaching

Standardization

ACIS: Proven Performance: Sample Article Listing

• Most peer reviewed imaging system on market

ACIS® Selected Article BibliographyAutomated System Improves Accuracy of HER-2 Scoring. ONI, April 2001.

Ayala G, Wang D, Wulf G., Frolov A, Li R, Sowadski J, Wheeler T, Lu K, Bao L. The Prolyl Isomerase Pin1 is a Novel Prognostic Marker in Human Prostate Cancer. Cancer Research 2003; Vol. 63, 6244-6251.

Bauer KD, Torre Bueno, J, Diel IJ, Hawes D, Decker WJ, Priddy C, Bossy B, Ludmann S, Yamamoto K, Masih AS, Espinoza FP, and Harrington DS. Reliable and Sensitive Analysis of Occult Bone Marrow Metastases Using Automated Cellular Imaging. In Autologous Blood and Marrow Transplantation X: Proceedings of the 10th International Symposium (K.A. Dicke and A. Keating, eds). 2001. Carden Jennings Publishing Co., Charlottesville, VA, 672-687.

Becker S, Becker-Pergola G, Fehm G, Emig R, Wallwiener D, Solomayer E-F.   Image Analysis Systems for the Detection of Disseminated Breast Cancer Cells on Bone-Marrow Cytospins.  Journal of Clinical Laboratory Analysis 19:115–119, 2005.

Birner P, Ritzi M, Musahl C, Knippers R, Gerdes J, Voigtlander T, Budka H, Hainfellner J. Immunohistochemical Detection of Cell Growth Fraction in Formalin-Fixed and Paraffin-Embedded Murine Tissue. Am J Pathol 2001; Vol. 158, 1991-1996.

Summary of Key Benefits of Dako Solution

True Positive ID Support

Connectivity Optimal Staining Performance

Easy-to-Use Software