ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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Transcript of ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
1/12
LHSNFLD FE@@MJM EH IML@QI (LFI)
LFI's C._ILSB ^MLS 1, VMBMVQMS 6, ZMMK = DEQMV7
BEDAL^7_ilrblfekndmtnfs (_j.3)
QMVAL^7_ilrblfekndmtnfs (_j.6)
ZMADMVAL^7_ilrblfekndmtnfs (_j.8)
QISVAL^7_ilrblfekndmtnfs (_j.>)
HSNAL^7 _ilrblfekndmtnfs (_j.
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
2/12
_ILSBLFEKNDMQNFV(BEDAL^)
FLSCED QMQSLFI@ESNAM7"ins febpeud# l`se bl$ #lbljm tim `n%mr ld#& `nkm
lfmtlbndepimd& nt ns det tim febpeud# ntsm`' cut l#mrn%ltn%m e' nt tilt ns #lbljndj. rmm rl#nfl`s lrm
'erbm# 'reb flrced tmtrlfi`ern#m c$ tim lftned e'
en#lsm md*$bms ed nt. "im pre#ufts e' 'rmm rl#nfl`
lftned lrm fed+ujltm# #nmdms winfi lrnsm 'reb `npn#
pmren#ltned. L`tieuji tim tenfnt$ e' flrced
tmtrlfi`ern#m c$ tins bmfildnsb ns det pre%m# cm$ed#
ld$ #euct& sm%mrl` `ndms e' m%n#mdfm suppert nt.
nrst& flrced tmtrlfi`ern#m mpesurm fld cm siewd te cm
spmfn'nfl``$ #lbljndj te bmbcrldms& winfi l`se lrm
kdewd te cm sntms 'er 'rmm rl#nfl` lttlfk. ,mfed#&
l#bndnstrltned e' ldtnen#ldts `nbnts #lbljm
flusm# c$ flrced tmtrlfi`ern#m. Ldtnen#ldts lrm l`se
kdewd te rm#ufm 'rmm rl#nfl` 'erbltned.-mlftn%m 'rmm
rl#nfl`s il%m l sbl`` rl#nus e' lftned (#um te
inji rmlftn%nt$) tius& #lbljm ns fmdtmrm# nd tim
fmdtrn`ecu`lr rmjned wimrm tim lftn%ltndj md*$bms lrm
prmsmdt nd tim `lrjmst lbeudt. "im pmre$ rl#nfl` ns
cm`nm%m# te cm tim blnd flusm e' `npn# pmren#ltned.
S$&+ Q*:"9"$"s
"imrm lrm twe kn#dm$s `efltm# nd tim bn##`m e' tim
clfk. lfi ns supp`nm# wnti c`ee# c$ l crldfi e' tim
#msfmd#ndj lertl fl``m# tim rmdl` lrtmr$. ?`ee# ns
'n`tmrm# c$ tim kn#dm$s ld# tim 'n`tmrm# pre#uft&
urndm& ns plssm# te tim urndlr$ c`l##mr %nl timurmtmrs. lfi kn#dm$ fedtlnds lceut
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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_ILSBLFEKNDMQNFV(QMVAL^)
SMDL@ HDFQNED7"im bl+er 'udftned e' tim kn#dm$s ns m`nbndltned e'
wlstm 'reb tim c`ee#. !ewm%mr& bld$ etimr nbpertldt
lftn%ntnms lrm flrrnm# eut c$ tins erjld& ndf`u#ndjbmtlce`nf prefmssms (l`tieuji `mss tild tim dubcmr
flrrnm# eut c$ tim `n%mr). "im kn#dm$ l`se
p`l$s l fmdtrl` re`m nd fedtre``ndj lfn#clsm cl`ldfm.
imd timrm ns ld lfn#clsm nbcl`ldfm nd tim c`ee#&
rmdl` febpmdsltned fld plrt`$ e''smt tim m''mfts e'
mfmss lfn# er clsm c$ rmju`ltndj tim rltm lt winfi
cnflrcedltm ns mfrmtm# ndte tim urndm."im kn#dm$ l`se fld fedtrncutm te i$#rejmd ned
iebmestlsns c$ pre#ufndj j`utlbndm 'reb j`utlbnf lfn#."ins ns nts bl+er bmtie# 'er #ubpndj mfmss i$#rejmd
ned #urndj mpnse#ms e' bmtlce`nf lfn#esns. !erbedl`
lftn%ntnms e' tim kn#dm$ ndf`u#m s$dtimsns e' rmdnd
(c`ee# prmssurm rmju`ltned)& mr$tirepenmtnd (rm# fm``
pre#uftned)& ld#
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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"im m`nbndltned lftn%nt$ e' tim kn#dm$ ns lfinm%m# c$
sm%mrl` strufturms wntind tim dmpired7 #+*$%>+",%*:"&+ >>+$s, &/ /"s&+ >>+$s. ?`ee# 'n`trltnedstlrts wntind tim j`ebmru`us. L`` e' tim se`utm wntind
c`ee# tilt ils be`mfu`lr wmnjit `mss tild lpprenbltm`$
& =l ns plssm# tireuji tim j`ebmru`lr bmbcrldm
ndte tim tucu`ms. Lceut
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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in`m tim prenbl` tucu`m fm``s lrm cus$ mtrlftndj
febpeud#s 'reb tim j`ebmru`lr 'n`trltm& ld# timrmc$
splrndj timb 'reb mfrmtned& tim$ lrm l`se mdjljm# nd
smfrmtned e' etimr sucstldfms. "ius& edm smms tilt tim
lftn%nt$ e' fm``s nd tim prenbl` tucu`ms ns inji`$
sepinstnfltm# ld# lfts c$ sm%mrl` bmfildnsbs te
rmju`ltm tim 'ndl` febpesntned e' tim 'n`trltm& tim
'`un# #mstndm# 'er m`nbndltned 'reb tim ce#$.
d tucu`lr smfrmtned tim su`'ltm ld# j`ururedn#m
fed+ujltms e' mdecnetnfs lrm lftn%m`$ trlds'mrrm# 'reb
c`ee# ndte tim j`ebmru`lr 'n`trltm. :timr lfn#s ld#
clsms lrm l`se ec+mfts e' tucu`lr smfrmtned. "ins
prefmss& wimd nt effurs nd l plssn%m blddmr& ns %mr$
bufi nd'`umdfm# c$ p!.
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
6/12
_ILSBLFEKNDMQNFV(ZMADMVAL^)
SMDL@ HDFQNED7"im bl+er 'udftned e' tim kn#dm$s ns m`nbndltned e'
wlstm 'reb tim c`ee#. !ewm%mr& bld$ etimr nbpertldt
lftn%ntnms lrm flrrnm# eut c$ tins erjld& ndf`u#ndjbmtlce`nf prefmssms (l`tieuji `mss tild tim dubcmr
flrrnm# eut c$ tim `n%mr). "im kn#dm$ l`se
p`l$s l fmdtrl` re`m nd fedtre``ndj lfn#clsm cl`ldfm.
imd timrm ns ld lfn#clsm nbcl`ldfm nd tim c`ee#&
rmdl` febpmdsltned fld plrt`$ e''smt tim m''mfts e'
mfmss lfn# er clsm c$ rmju`ltndj tim rltm lt winfi
cnflrcedltm ns mfrmtm# ndte tim urndm."im kn#dm$ l`se fld fedtrncutm te i$#rejmd ned
iebmestlsns c$ pre#ufndj j`utlbndm 'reb j`utlbnf lfn#."ins ns nts bl+er bmtie# 'er #ubpndj mfmss i$#rejmd
ned #urndj mpnse#ms e' bmtlce`nf lfn#esns. !erbedl`
lftn%ntnms e' tim kn#dm$ ndf`u#m s$dtimsns e' rmdnd
(c`ee# prmssurm rmju`ltned)& mr$tirepenmtnd (rm# fm``
pre#uftned)& ld#
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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"im m`nbndltned lftn%nt$ e' tim kn#dm$ ns lfinm%m# c$
sm%mrl` strufturms wntind tim dmpired7 #+*$%>+",%*:"&+ >>+$s, &/ /"s&+ >>+$s. ?`ee# 'n`trltnedstlrts wntind tim j`ebmru`us. L`` e' tim se`utm wntind
c`ee# tilt ils be`mfu`lr wmnjit `mss tild lpprenbltm`$
& =l ns plssm# tireuji tim j`ebmru`lr bmbcrldm
ndte tim tucu`ms. Lceut
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
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in`m tim prenbl` tucu`m fm``s lrm cus$ mtrlftndj
febpeud#s 'reb tim j`ebmru`lr 'n`trltm& ld# timrmc$
splrndj timb 'reb mfrmtned& tim$ lrm l`se mdjljm# nd
smfrmtned e' etimr sucstldfms. "ius& edm smms tilt tim
lftn%nt$ e' fm``s nd tim prenbl` tucu`ms ns inji`$
sepinstnfltm# ld# lfts c$ sm%mrl` bmfildnsbs te
rmju`ltm tim 'ndl` febpesntned e' tim 'n`trltm& tim
'`un# #mstndm# 'er m`nbndltned 'reb tim ce#$.
d tucu`lr smfrmtned tim su`'ltm ld# j`ururedn#m
fed+ujltms e' mdecnetnfs lrm lftn%m`$ trlds'mrrm# 'reb
c`ee# ndte tim j`ebmru`lr 'n`trltm. :timr lfn#s ld#
clsms lrm l`se ec+mfts e' tucu`lr smfrmtned. "ins
prefmss& wimd nt effurs nd l plssn%m blddmr& ns %mr$
bufi nd'`umdfm# c$ p!.
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
9/12
_ILSBLFEKNDMQNFV(QISVAL^)
DM_ISEQE;NFLDQV7
BMQL@V0
4mtl`s& plrtnfu`lr`$ iml%$ edms& lrm flplc`m e' flusndjkn#dm$ #lbljm. "im spmfn'nf sntm e' #lbljm ns usul``$
tim prenbl` tucu`ms ld# fm`` #mlti er nbplnrbmdt
rmsu`ts. Lt l cnefimbnfl` `m%m` bmtl`s cnd# te
su`'i$#r$` jreups ed pretmnds 'eud# nd bmbcrldms
er nd md*$bms& ld# timrmc$ ndtmr'mrm wnti derbl`
'udftned `ml#ndj te %lrneus #mjrmms e' rm#ufm# 'udftned
er #mlti. Lt `mlst edm bmtl`& bmrfur$& ns cm`nm%m# te
il%m edm l##ntnedl` #m`mtmrneus lftned& dlbm`$&
fedstrnftned e' c`ee# %mssm`s wnti l fedsm5umdt
rm#uftned e' c`ee# '`ew ld# e$jmd supp`$ te rmdl`
tnssum.
F-%*">ils l #n''mrmdt m''mft 'reb bmrfur$. tndincnts j`ufesm rmlcserptned c$ #lbljndj tim prenbl`
fed%e`utm# tucu`m& tim sntm e' j`ufesm rmuptlkm.
irebnub tenfnt$ #mpmd#s jrmlt`$ ed tim en#ltned
stltm e' firebnub. ' tim en#ltned stltm ns 6O& tim
firebnub ns rm`ltn%m`$ dedtenf ld# ns lcsercm# te l
%mr$ `nbntm# #mjrmm. imd tim en#ltned stltm ns 8O&iewm%mr& tim firebnub ns rm#ufm# c$ ndtrlfm``u`lr
md*$bms. d tim prefmss& 'rmm rl#nfl`s lrm 'erbm# ld#
#nsrupt bld$ fm``u`lr prefmssms.
@$&/ns l iml%$ bmtl` winfi ns tlkmd up c$ prenbl`tucu`m fm``s. ntind timsm fm``s `ml# ndtmr'mrms wnti
bntefied#rnl` cnefimbnstr$. "im fm`` ils sebm lcn`nt$
te #mten'$ `ml# ld# lppmlrs te #e tins te sebm #mjrmm
c$ 'erbndj ndf`usned ce#nms e' `ml# ced#m# te lfn#nf
pretmnds. ,ufi ce#nms& winfi lppmlr cm'erm `ml#tenfnt$ stlrts& bl$ cm smmd ls bnfresfepnf ndf`usneds
wntind tim fm``.
F&/">(ltebnf wmnjit
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
10/12
nd tim iubld ce#$& lpprenbltm`$
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
11/12
_ILSBLFEKNDMQNFV(HSNAL^)
DM_ISEQE;NFLDQV7
BMQL@V0
4mtl`s& plrtnfu`lr`$ iml%$ edms& lrm flplc`m e' flusndjkn#dm$ #lbljm. "im spmfn'nf sntm e' #lbljm ns usul``$
tim prenbl` tucu`ms ld# fm`` #mlti er nbplnrbmdt
rmsu`ts. Lt l cnefimbnfl` `m%m` bmtl`s cnd# te
su`'i$#r$` jreups ed pretmnds 'eud# nd bmbcrldms
er nd md*$bms& ld# timrmc$ ndtmr'mrm wnti derbl`
'udftned `ml#ndj te %lrneus #mjrmms e' rm#ufm# 'udftned
er #mlti. Lt `mlst edm bmtl`& bmrfur$& ns cm`nm%m# te
il%m edm l##ntnedl` #m`mtmrneus lftned& dlbm`$&
fedstrnftned e' c`ee# %mssm`s wnti l fedsm5umdt
rm#uftned e' c`ee# '`ew ld# e$jmd supp`$ te rmdl`
tnssum.
F-%*">ils l #n''mrmdt m''mft 'reb bmrfur$. tndincnts j`ufesm rmlcserptned c$ #lbljndj tim prenbl`
fed%e`utm# tucu`m& tim sntm e' j`ufesm rmuptlkm.
irebnub tenfnt$ #mpmd#s jrmlt`$ ed tim en#ltned
stltm e' firebnub. ' tim en#ltned stltm ns 6O& tim
firebnub ns rm`ltn%m`$ dedtenf ld# ns lcsercm# te l
%mr$ `nbntm# #mjrmm. imd tim en#ltned stltm ns 8O&iewm%mr& tim firebnub ns rm#ufm# c$ ndtrlfm``u`lr
md*$bms. d tim prefmss& 'rmm rl#nfl`s lrm 'erbm# ld#
#nsrupt bld$ fm``u`lr prefmssms.
@$&/ns l iml%$ bmtl` winfi ns tlkmd up c$ prenbl`tucu`m fm``s. ntind timsm fm``s `ml# ndtmr'mrms wnti
bntefied#rnl` cnefimbnstr$. "im fm`` ils sebm lcn`nt$
te #mten'$ `ml# ld# lppmlrs te #e tins te sebm #mjrmm
c$ 'erbndj ndf`usned ce#nms e' `ml# ced#m# te lfn#nf
pretmnds. ,ufi ce#nms& winfi lppmlr cm'erm `ml#tenfnt$ stlrts& bl$ cm smmd ls bnfresfepnf ndf`usneds
wntind tim fm``.
F&/">(ltebnf wmnjit
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7/21/2019 ACH's B.PHARM YEAR 4, SEMESTER 3, WEEK 5 NOTES
12/12
nd tim iubld ce#$& lpprenbltm`$
