AccuTOF GCv G - JEOL USA GCv 4 G High Performance Gas Chromatograph – Time-of-Flight Mass...

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AccuTOF GCv 4G High Performance Gas Chromatograph – Time-of-Flight Mass Spectrometer JEOL JMS-T100GCV AccuTOF GCv 4G Serving Advanced Technology Easy instrument tuning by Tuning Assistant Installation requirements Power supply Main console Single phase AC190- 210V or 220– 240V, 20A, 50-60Hz Gas chromatograph Single phase, AC 200V or 220V or 230V or 240V, 20 A Data system AC100-120V, 15A, 50-60Hz AC200-240V, 7.5A, 50-60Hz Grounding 100 Ω or less Nitrogen gas For purging ion source 0.5 to 0.6 MPa, 97% or better purity and analyzer For driving valves Helium gas For gas chromatograph 0.5 to 0.68MPa, 99.999% or better purity, 0.5ppm or less hydrocarbon content Installation room Varying magnetic field 1×10 -6 T or less Static magnetic field 5×10 -4 T or less Floor vibration Amplitude (p-p) 25 μm or less, acceleration 0.1 m/s 2 or less Room temperature 20 to 27 °C Temperature fluctuation ±3 °C / h or less Humidity 30 to 70% (no condensation) Maximum heat generation 25,560 kJ/h (calculated from maximum power consumptions of mass spectrometer, gas chromatograph, and data system) Ventilation facility Ventilation facility for rotary pump exhaust is required •Power supply requirement depends on a specific configuration sold in each territory. Please inquire a local sales office for details. Standard configuration Ion source Electron ionization Analyzer Reflectron time-of-flight mass analyzer Ion detector Dual microchannel plate Data acquisition system continuous averager Vacuum system 2 turbo molecular pumps 2 rotary pumps Gas chromatograph Agilent 7890A Data system Personal computer, LCD monitor, laser printer, rewritable DVD drive, Windows operating system, data system software (MassCenter TM ) Major optional attachments Direct insertion probe FD/FI combination source Direct exposure probe EI/FI/FD combination source CI source NIST library database Example of an installation room User-friendly operation! Installation example Symbol Unit Width(mm) Depth(mm) Height(mm) Weight (kg) A Mass spectrometer 1,172 724 1,155 331 B Gas chromatograph 582 513 488 49 C Computer 168 450 456 15 C' TFT LCD monitor 443 220 555 9.2 D Laser printer 385 279 261 6 * Specifications subject to change without prior notice. Simplified direct sample introduction (DEP, DIP, FD) Easy linkage to various optional software Escrime for batch quantitative analysis of multiple components Polymerix™ *1 for analysis of polymers/hydrocarbon types GC Image™ *2 for GCxGC analysis Mass Mountaineer™ *3 for isotopic pattern analysis Diok for qualitative/quantitative analysis of environmental pollutants *1 Sierra Analytics, Inc. *2 GC Image, LLC *3 ChemSW Performance Mass accuracy : 1.5mDa or 4 ppm (r.m.s.) Mass Resolution : R 8000 ( m/z 617) Sensitivity : S/N 100 (OFN 1pg) Data recording speed : Up to 50 spectra/s Mass range : m/z 4 5000 No.2302I294C(Bn)

Transcript of AccuTOF GCv G - JEOL USA GCv 4 G High Performance Gas Chromatograph – Time-of-Flight Mass...

Page 1: AccuTOF GCv G - JEOL USA GCv 4 G High Performance Gas Chromatograph – Time-of-Flight Mass Spectrometer JEOL JMS-T100GCV AccuTOF GCv 4G Serving Advanced Technology

AccuTOF GCv 4GHigh Performance Gas Chromatograph – Time-of-Flight Mass Spectrometer

J E O L J M S - T 1 0 0 G C VA c c uTO F G C v 4 G

Serving Advanced Technology

Easy instrument tuning by Tuning Assistant

Installation requirementsPower supply Main console Single phase AC190- 210V or 220– 240V, 20A, 50-60Hz Gas chromatograph Single phase, AC 200V or 220V or 230V or 240V, 20 A Data system AC100-120V, 15A, 50-60Hz AC200-240V, 7.5A, 50-60HzGrounding 100 Ω or lessNitrogen gas For purging ion source 0.5 to 0.6 MPa, 97% or better purity and analyzer For driving valves Helium gas For gas chromatograph 0.5 to 0.68MPa, 99.999% or better purity, 0.5ppm or less hydrocarbon contentInstallation room Varying magnetic field 1×10-6 T or less Static magnetic field 5×10-4 T or less Floor vibration Amplitude (p-p) 25 μm or less, acceleration 0.1 m/s2 or less Room temperature 20 to 27 °C Temperature fluctuation ±3 °C / h or less Humidity 30 to 70% (no condensation) Maximum heat generation 25,560 kJ/h (calculated from maximum power consumptions of mass spectrometer, gas chromatograph, and data system) Ventilation facility Ventilation facility for rotary pump exhaust is required

•Power supply requirement depends on a specific configuration sold in each territory. Please inquire a local sales office for details.

Standard configurationIon source Electron ionizationAnalyzer Reflectron time-of-flight mass analyzerIon detector Dual microchannel plateData acquisition system continuous averagerVacuum system 2 turbo molecular pumps 2 rotary pumpsGas chromatograph Agilent 7890AData system Personal computer, LCD monitor, laser printer, rewritable DVD drive, Windows operating system, data system software (MassCenterTM)

Major optional attachments・Direct insertion probe ・FD/FI combination source・Direct exposure probe ・EI/FI/FD combination source・CI source ・NIST library database

Example of an installation room

User-friendly operation!

Installation exampleSymbol Unit Width(mm) Depth(mm) Height(mm) Weight (kg)

A Mass spectrometer 1,172 724 1,155 331 B Gas chromatograph 582 513 488 49 C Computer 168 450 456 15 C' TFT LCD monitor 443 220 555 9.2 D Laser printer 385 279 261 6

* Specifications subject to change without prior notice.

Simplified direct sample introduction (DEP, DIP, FD)Easy linkage to various optional software ・Escrime for batch quantitative analysis of multiple components ・Polymerix™*1 for analysis of polymers/hydrocarbon types ・GC Image™*2 for GCxGC analysis ・Mass Mountaineer™*3 for isotopic pattern analysis ・Diok for qualitative/quantitative analysis of environmental pollutants

*1 Sierra Analytics, Inc. *2 GC Image, LLC *3 ChemSW

PerformanceMass accuracy : 1.5mDa or 4 ppm (r.m.s.)Mass Resolution : R ≧ 8000 (m/z 617)Sensitivity : S/N ≧ 100 (OFN 1pg)Data recording speed : Up to 50 spectra/sMass range : m/z 4~ 5000

No.2302I294C(Bn)

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JEOL announces the AccuTOF GCv 4G, a 3rd generation product of the AccuTOF GC series. The AccuTOF GCv 4G, featuring JEOL's innovative technologies, is a powerful tool for a wide range of applications. It is a high-resolution GC-TOFMS that combines versatility and high performance.

Various ionization and sample introduction techniques

While electron ionization (EI) is effective in acquiring structural information in GC/MS, detection of molecular ions is critical in qualitative analysis. In addition to chemical ionization (CI,) the AccuTOF GCv 4G supports field ionization (FI) and field desorption (FD,) powerful soft ionization techniques for molecular ion detection. The system also supports direct sample introduction for analysis of high-boiling-point compounds and rapid analysis.

Reliable determination of elemental composition

The high resolution and high mass accuracy AccuTOF GCv 4G makes it possible to accurately determine elemental composition.It is a powerful tool in qualitative analysis of unknown compounds and impurities.

High-speed data acquisition

The AccuTOF GCv 4G supports fast GC for high-throughput analysis. It also supports GCxGC to achieve ultrahigh separation analysis.

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Material Sciencep3

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General Chemistry

PolymersFood Safety

Fragrances

Environmental Science

Petroleum Products

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A wide range of applications

The AccuTOF GCv 4G is a superior TOFMS system that combines high-resolution analysis, high mass accuracy, and high-speed data acquisition.

Application 1

Application 2

Application 3

Application 4Application 5

Application 6

Application 7

AccuTOF GCv 4GVersatile high-performance TOFMS -

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GC/EI

Total Ion Current Chromatograms (TICC)GC/FI

Structural formula

FI allows for observation of molecular ions.

M+・348

147

201

Whi le no molecu la r ions a re observed in EI, the structure of the sample can be determined from the exact mass of fragment ions.

147

119

201

Unreacted polymerization initiator

Combining EI, a hard ionization technique, and FI, a soft ionization technique, allows for determination of the structural formula of a compound.

119.08526 17476.46 119.08608 -0.82 C₉H₁₁ 4.5

147.08013 75466.86 147.08099 -0.86 C₁₀H₁₁0 5.5

201.04750 06782.81 201.04693 -0.58 C₁₂H₁₀0P 9.5

348.12829 4259.38 348.12792 0.37 C₂₂H₂₁0₂P 14.0

Since FI does not ionize column bleed, the TICC clearly shows the high-boiling-point compounds.

2. Analysis of high-boiling-point compounds (antioxidant) (MS Tips No. 123)

TICC (Sample : Irganox 1010)TICC (Sample : Cholesterol)

EI FI

GC/EI GC/EI

GC/FI GC/FI

Intensity

Intensity

RelativeIntensity

RelativeIntensity

Intensity Intensity

Intensity

Intensity

Retentiontime[min]Retentiontime[min]

Retentiontime[min]Retentiontime[min]Cholesterol Irganox 1010

Advantages of FI

Field Ionization (FI) - An ideal ionization technique for molecular weight determination !

FI ionizes the sample by tunneling electrons from the molecules in the presence of a high electric field.

Carbon emitter

● FI (Field Ionization)A sample vaporized by GC or the standard sample inlet is introduced to the vicinity of the emitter.

A soft ionization technique with minimal fragmentation, FI is ideal for samples that are volatile but easily fragmented with EI or CI.Unlike CI, FI uses no reagent gas ; no need to choose a reagent gas appropriate for the analyte.

Principle of FI

1. Qualitative analysis of an initiator in an adhesive (MS Tips No. 108)

The AccTOF GCv 4G is effective in qualitative analysis of unknown components such as impurities.

Material ScienceApplication 1

Mass Spectra

1. EI + Exact mass analysis = Determination of structural formula 2. FI + Exact mass analysis = Determination of compositional formula

m/z m/z

e-

10kV

Cathode

Column

MS

Anode(Emitter)

Current

Gas-phase molecules

M+・,[M+H]+,etc

Measuredaccuratemass

Measuredaccuratemass

Intensity

Intensity

Calculatedexactmass

Calculatedexactmass

Error(10-³)

Error(10-³)

Inferredformula

Inferredformula

Unsaturation

Unsaturation

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Direct sample inlet system

The AccuTOF GCv 4G uses 2 different types of direct sample inlet probes depending on the application. EI and CI are supported for these probes.

● DEP (Direct Exposure Probe)High-boiling-point compound/thermally labile compoundThe sample, which is dissolved in a solvent, is applied to the filament at the tip.

● DIP (Direct Insertion Probe)High-boiling-point compound/sample insoluble in solventThe sample is housed in a dedicated glass sample tube.

Platinum coil filament

Glass sample tube

3. Analysis of pigments Analysis of tristearin

4. Analysis of an ionic liquid sample (MS Tips No. 113)

5. Analysis of a fluorine compound

Using FD ionization, the AccuTOF GCv 4G detected molecular ions for the refractory and insoluble pigments.

Copper phthalocyanine (top)C₃₂H₁₆CuN₈575.07939

C₃₂Cl₁₆CuN₈1118.45584

Pigment Green 7 (bottom)

FD makes it easier to detect cations and cluster ions. Further accurate-mass analysis allows for determination of the elemental formula of each compound.

Cationic compound (C) : PyridineAnionic compound (A) : Fluorinated (triflate) ionic liquid

[C]⁺ 150.1289 150.1283 0.6 C₁₀H₁₆N

[C₂A]⁺ 580.1766 580.1738 2.80 C₂₂H3₂F₆N₃O₄S₂

[C]⁺150.1

[C₂A]⁺580.2

(C) (A)

FI is a soft ionization technique applicable to volatile samples. Molecular ions of the easily fragmented fluorine compound were detected as well.

C₃HCl₂F₅Mw:202

General ChemistryApplication 2

2 types of direct sample inlet probes

Using DEP, the AccuTOF GCv 4G detected tristearin, a high-boiling-point compound. Speedy analysis in less than 1 minute makes the system ideal for the confirmation of synthetic chemicals.

Tristearin(C₅₇H₁₁₀O₈)MS method●Spectrumrecordinginterval:0.2s●Masrange:m/z36to950●DEPcurrent:1A(maximum)●ReagentgasforDCI:Ammonia

267

341

607

872

[M]M+・890

607

[M+NH4]+908

m/z

m/z m/z

m/z

m/z

m/z

Intensity

Intensity

Intensity Intensity

Intensity

Intensity

M+・575.08

M+・1118.46

M+・201.9

Desorption/electron ionization (DEI; EI with DEP)

FD

FD

FI

Desorption/chemical ionization (DCI; CI with DEP)

Measuredaccuratemass

Calculatedexactmass Error(10-³) InferredformulaIonicspecies

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10kV

MS

Solid-phase molecules

e-

Anode(Emitter)

Current

Cathode

M+・,[M+H]+,etc

Elemental composition determination

The mass spectrum acquired from polystyrene 4000 using FD ionization shows ions at m/z 5500 or higher. The AccuTOF GCv 4G is effective for polymer analysis in the oligomer range in addition to GC/MS analysis. For FD ionization, the system is capable of speedy data acquisition within 1 minute.

3. Calculating the average molecular weight of polystyrene using FD1. Pyrolysis GC/MS of an acrylic resin (MS Tips No. 101)

2. Thermal extraction GC/MS (MS Tips No. 138)

PolymersApplication 3

Pyrolysis GC/MS is widely used as an analytical technique for high molecular weight polymers. Instant thermal decomposition makes it a simple yet powerful technique with high reproducibility.

GC/TOFMS, which is capable of acquiring exact-mass results in a single GC/MS analysis, enhances the reliability of library search results. It is also effective for qualitative analysis of peaks that cannot be identified through library search. The system also acquires accurate distribution of isotopes of molecular ions, which is effective in molecular identification.

A d d i t i v e s d e t e c t e d a r e s q u a l e n e , decabromodiphenyl ethane (bromine flame regardant), Irganox 1330 (antioxidant).

TICC

TICC of acrylic resin Pyrolysis GC/EI/TOFMS

TICC (GC/EI)

EI mass spectrum of Peak at 9.25 min (upper☆ )

Chargenumber:1Tolerance:5.00(mDa)Element:¹²C:0~100, ¹¹H:0~200, ¹⁶O:0~10, ³²S:0~1

46.99437 46.99555 -0.81 ¹²C₁¹H₃³²S₁ 1.5

55.05387 55.05478 -0.90 ¹²C₄¹H₇ 1.5

69.06963 69.07043 -0.80 ¹²C₅¹H₉ 1.5

83.08569 83.08608 -0.39 ¹²C₆¹H₁₁ 1.5-

112.12456 112.12520 -0.64 ¹²C₈¹H₁₆ 1.0

146.11280 146.11292 -0.12 ¹²C₈¹H₁₈³²S₁ 1.0

146.10955 3.25 ¹²C₁₁¹H₁₄ 5.0

Using thermal extraction GC/TOFMS, the system analyzed additives in a resin.

Advantages of FD

Field Desorption (FD) - An ionization technique ideal for molecular weight determination !

FD ionizes the sample by tunneling electrons from the molecules in the presence of a high electric field.

Carbon emitter

The sample is applied onto the emitter.

Principle of FD

A soft ionization technique with minimal fragmentation, FD is ideal for samples that are non-volatile and thermally labile.Unlike CI and DCI, FD uses no regent gas; no need to choose a reagent gas appropriate for the analyte.FD is applicable to insoluble samples.

m/z

m/z

m/z

Mn Mw PD DPn DPw

3583.07 3805.72 1.062 33.89 36.03

m/z

Intensity

Intensity

Retentiontime[min]

RelativeIntensity

RelativeIntensity

Simulation of isotope pattern

Intensity

Mn: NumberaveragemolecularweightMw: WeightaveragemolecularweightPD: PolydispersityDPn:NumberaveragedegreeofpolymerizationDPw:Weightaveragedegreeofpolymerization

Polymerix bySierra Analytics used for analysis .Polymerixiscapableofpolymerandtypeanalysis.

Retentiontime[min]

Methyl methacrylate

Methyl acrylate

Measuredaccuratemass

Calculatedexactmass Error(10-³) Inferredformula Unsaturation

FD mass spectrum of polystyrene 4000

RelativeIntensity

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GCxGC (comprehensive 2D GC)

The AccTOF GCv 4G is capable of ultrahigh separation GCxGC analysis while maintaining ample data points.

GCxGC is a continuous heart-cut system designed to use 2 columns having different polarities, trap the eluted components using a modulator in the 1st column at given intervals, and perform high-speed analysis of the trapped components in the 2nd column. GCxGC is a powerful capillary GC technique that features higher resolution than traditional capillary GC and is capable of high-sensitivity analysis of components by the group. It requires a detector capable of high-speed data acquisition. Because the peak widths of the chromatogram are extremely sharp compared to traditional capillary GC.

1. Ultrahigh separation analysis of diesel fuel (GCxGC/TOFMS analysis) Ultrahigh separation analysis of aroma oil (GCxGC/TOFMS analysis)

2. Type analysis of microcrystalline wax (MS Tips No. 100)

ZOEX GCxGC system used for measurementGCxGC chromatogram created by ZOEX GC Image software

FD mass spectrum of microcrystalline wax

Group-type analysis of microcrystalline wax

FragrancesApplication 5

Petroleum ProductsApplication 4

E x a c t m a s s m e a s u r e m e n t i s e a s i l y accomplished for GCxGC analysis. By combining high resolution with GCxGC, the system can qualitatively analyze trace components.

SeriesLabel Mn Mw Mz PD DPn DPw DPz PercetSeries PercentSpectrum

Total/Average 657.0 686.9 718.9 1.0 40.1 42.2 44.5 100.0 64.1

S1 CnH₂n+₂ 571.1 617.3 665.3 1.1 33.6 36.9 40.3 17.3 11.1

S2 CnH₂n 529.7 655.0 680.8 1.0 37.9 39.7 41.6 24.2 15.5

S3 CnH₂n-₂ 670.5 692.3 715.6 1.0 41.0 42.5 44.2 13.1 8.4

S4 CnH₂n-₄ 715.6 739.0 764.7 1.0 44.3 46.0 47.8 8.4 5.4

S5 CnH₂n-₆ 688.3 717.9 751.1 1.0 42.5 44.7 47.0 22.5 14.5

S6 CnH₂n-₈ 710.0 739.6 772.8 1.0 44.2 46.3 48.7 14.5 9.3

Mn: NumberaveragemolecularweightMw: WeightaveragemolecularweightMz: ZaveragemolecularweightPD: PolydispersityindexDPn:NumberaveragedegreeofplymerizationDPw:WeightaveragedegreeofpolymerizationDPz:Zaveragedegreeofpolymerization

Type analysis makes it easy to obtain the average molecular weight, molecular weight distribution, and the content of hydrocarbons having different degrees of unsaturation.

The compounds in the aroma oil were fully separated for grouping. The data offers a visual representation of the complex aroma oil composition.

For compounds that do not produce molecular ions by EI, FI can be used to detect molecular ions, and determine the elemental composition, which enhances the accuracy of qualitative analysis.

1st column (non-polar) separation; Boiling point

1st column (non-polar) separation; Boiling point

2nd

colu

mn

(pol

ar) s

epar

atio

n; P

olar

ity

2nd

colu

mn

(pol

ar) s

epar

atio

n; P

olar

ity

2-dimensional (2D) TICC of diesel fuel by GCxGC/TOFMS

2D TICC of tea tree oil by GCxGC/TOFMS

Injector

Modulator

Modulator:Continuously repeats cold trapping and thermal desorption in every 3 to 7 seconds

2nd column:Repeats fast separations in every 3 to 7 secondsEx.: BPX50 (2m x 0.10mm, 0.10μm)

2nd column:Repeats fast separations in every 3 to 7 secondsEx.: BPX50 (2m x 0.10mm, 0.10μm)

2nd columnGC Oven

1st column

AccuTOF GCv 4G・Always run at high mass resolution・Accurate mass measurement

Detecor: MS, etc.

1st column:Ordinary capillary GC columnEx.: BPX5 (30m x 0.25mm, 0.25μm)

AccuTOF GCv 4G・Always run at high mass resolution・Accurate mass measurement

1st column:Ordinary capillary GC columnEx.: BPX5 (30m x 0.25mm, 0.25μm)

Modulator:Continuously repeats cold trapping and thermal desorption in every 3 to 7 seconds

Retention time[min]

Intensity

Peak width: 0.18 sec

9 data points

m/z

Intensity

m/z

m/z

Intensity

Intensity

Cyclic monoterpene diols and triols

Acyclic monoterpene alcohols

Cyclic monoterpene alcohols

Cyclic sesquiterpene alcohol

Cyclic sesquiterpenes

Cyclic monoterpenes

Molecular ion not detected

Molecular ion detectedm/z error: -1.17 x 10⁻³

Zoex’s GC x GC system is provided and supported through Zoex’s sales and support network, and may not be available in your territory. Contact your local JEOL representative for detail.

FI

EI

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Software for simultaneous quantitative analysis of multiple components - “Escrime”

Escrime is designed to calculate areas, plot calibration curves, and determine quantitative values. With further manipulation of the resulting data including separate or collective editing of area calculation ranges, the software speeds up the quantitation process significantly.

These chromatograms show the presence of 100 pesticide components. In the Fast GC analysis (top), the system acquired data while maintaining chromatographic separation in less than 1/4 of the time needed for the conventional analysis (bottom). The 50 spectra/second high-speed data acquisition system enables high-throughput analysis.

Measurementtime:8minutes

Measurementtime:38minutes

Fast GC/MS

Conventional

Excellent separation

Analysis of residual agricultural chemicals in food products Analysis of PCBs in oil (FastGC) (MS Tips No. 130)

High-throughput analysis - FastGC

High selectivity

Simple analytical conditions

Superior qualitative capability

Superior sensitivity/reproducibility

Food SafetyApplication 6

Environmental ScienceApplication 7

STD

Sample+

STD

Sample

GC/QMS equivalent GC/TOFMS

Interference

Interference

No Interference

N.D

High-resolution TOFMS can reduce the interference from matrix. Peaks from the matrix that are detected at low resolution will be eliminated at high resolution. This high selectivity reduces false positive and allows for more accurate quantitation.

GC/TOFMS detects all components that are ionized. Thus, the operator is freed from the lengthy process of defining analytical conditions such as SIM (Selected Ion Monitoring) and SRM (Selected Reaction Monitoring). Theoretically, there is no limit on the number of components that can be analyzed. The AccuTOF GCv 4G can perform simple simultaneous analysis of multiple components using its unique exact mass database for approximately 350 components (1 quantitative ion and 4 qualitative ions per component, editable).

TOFMS performs high-resolution, high-mass-accuracy analysis over a wide m/z range (m/z 35 to 600) without selecting a measurement mode such as SCAN and SIM. As a result, it allows for acquisition of highly selective chromatograms for all ions observed, demonstrating its superior qualitative capability. The acquired data can be used to analyze non target compounds as well.

The table on the right shows the limit of quantitation and the relative standard deviation of 353 components that were analyzed simultaneously. The results demonstrate superior sensitivity and reproducibility for simultaneous analysis of multiple components

LimitofQuantitation(LOQ*)  % RSD

<0.005ppm 161 <5% 239

0.005ppm-0.01ppm 174 5 ~ 10% 109

>0.01ppm 18 >10% 5

High selectivity at high resolution makes it possible to detect the PCBs contained in an oil sample.

The EICC acquired with the window width set to low resolution (top, equal to QMS) was unable to eliminate the oil interference from the PCB impurities. The high-resolution mass chromatogram (bottom) successfully detected the peaks of pentachlorinated PCBs by eliminating the interference.

Peak area range

Blank

0.1 ppb

1 ppb

10 ppb

Sample

Peaks of the components contained in multiple samples or peaks of multiple components in a single sample can be presented on a single view. The peak area calculation ranges can be simultaneously changed, allowing for batch analysis of more than 150 samples.

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Intensity

Retentiontime[min]Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Retentiontime[min]

Extracted Ion Current Chromatograms (EICC)

*LOQ defined as 10 times the standard deviation of the quantitation values obtained from 5 repeated injections of 40 pg (20 ppb x 2 μL) of each compound.

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Successfully eliminates 99.9% or more of He ions

Plug & socket chamber● Allows for selective cleaning of the

ionization chamber● Easy filament exchange● EI/CI selection accomplished by simply

replacing the "plug & socket" chamber

Sourcemagnet Intermediateslit

Socket-typechamber

Isolationvalve

DeflectorAnalyteions

HeliumionsAutomated isolation valve allows you to clean or change the ion source, or replace the GC column without breaking the vacuum of the TOF mass analyzer.

● Source magnet : Lower m/z ions (e.g.,He⁺) are deflected more than higher m/z ions.● Lens 2 : Optimizing the voltages on the lens 2 electrodes (upper and lower) guides analyte

ions through the intermediate slit while helium ions are rejected at the slit.● Deflectors : Corrects the trajectory of analyte ions to the TOF mass analyzer.

to TOFMS

Electrostaticlenses

Stable high-transmission-rate (=high sensitivity) ion transfer systemLonger life of detector

Ion source and ion transfer system (Patent JP3967694, US7034288, GB2404080)

EI/FI/FD combination ion source (optional)

Detector

Analyzer

Data Acquisition System

FeaturesA single ion source supports EI (hard ionization) and FI/FD (soft ionization) techniques.Switching between EI and FI/FD is simple and quick.

● No need to change the ion source● No need to change the GC-interface● No need to break vacuum

Effective use of EI/FI/FD:● EI for qualitative analysis through library search● FI for molecular weight determination● GC/FI for type analysis of hydrocarbon samples● FD for polymer analysis● Accurate mass measurement

The analyzer uses 2 stage acceleration (spatial focusing) and reflectron (energy focusing) to insure stable high-resolution analysis at all times. It also employs oa-TOFMS (orthogonal acceleration time-of-flight MS) for efficient use of ions from the ion source.

Two microchannel plates (MCP) are used to detect ions at high sensitivity. The new patented anode forms a new electric detection circuit, and its superior response enhances the level of sensitivity as well.

Data recording speed of up to 50 spectra/sec       -High-throughput analysis-

Continuous averager free from the problems with conventional TDC - Accurate mass reproducibility without correction -

A new high-speed preamp/data acquisition system is capable of sampling TOFMS signals at 4 giga samples/second, twice faster than the previous model. This enables higher mass-resolving power and higher mass-accuracy analysis.

Two signal processing techniques have been used for TOFMS: TDC (Time-to-Digital Converter) and continuous averager. TDC requires statistical correction, and as a result the mass accuracy is determined by the correction parameters corresponding to the number of ions detected. The AccuTOF GCv 4G uses a continuous averager that is capable of continuous signal accumulation in real time, achieving high mass accuracies without data correction.

channel

microchannel plate(MCP)

Analyzer

Detecter

TMP1

RP1 RP2

TMP2

Isolation valveIon source and ion-transfer system to Data acquisi-

tion system

Proven PerformanceApplication 7

The AccuTOF GCv 4G delivers reliability through innovation.