Accomplishments & Outcomes: Genomics Successes in Oregon Amy Zlot Oregon Genetics Program.

Accomplishments & Outcomes:Genomics Successes in Oregon

Amy ZlotOregon Genetics Program

GENOMICS JEOPARDY

Dissemination: Tools, Products & Articles

Family History & Genetics

Surveillance & Analysis

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Oregon Genetics Program FINAL JEOPARDY

Q: The article published in the April 2007 issue of CDC's Preventing Chronic Disease emphasizes the multifactorial nature of this common condition:

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Tools, Products & Articles 200

Q: The article published in the April 2007 issue of CDC's Preventing Chronic Disease emphasizes the multifactorial nature of this common condition:

A: What is obesity?

GENOMICS JEOPARDY

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Q: The number of peer-reviewed journal articles published (or accepted for publication) by our program since the inception of the CDC Genomics Grant in 2004:


A: What are four?

Q: The number of peer-reviewed journal articles published (or accepted for publication) by our program since the inception of the CDC Genomics Grant in 2004:

Peer-Reviewed Journal Articles

• Primary Care - 2004Genetics for targeting disease prevention: diabetes

• Preventing Chronic Disease - 2005Perceived likelihood of developing diabetes among high-risk Oregonians

• Preventing Chronic Disease - 2007Addressing the obesity epidemic: a genomics perspective

• Preventing Chronic Disease – 2008 (accepted)

Influence of family history of diabetes on health care provider practice and patient behavior among non-diabetic Oregonians

GENOMICS JEOPARDY

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Q: This tool was developed in collaboration with select Federally-qualified Health Center (FQHC) providers to improve the collection of family history information:


Q: This tool was developed in collaboration with select Federally-qualified Health Center (FQHC) providers to improve the collection of family history information:

A: What is a template (family history form) to collect family history information in a FQHC setting?

Family Health History Have any of your close blood relatives (grandparents, parents, brothers, sisters, children) ever had the following?

Disease Yes No Which Relative? Age at Diagnosis

High Blood Pressure Heart Disease Diabetes Stroke Asthma Breast Cancer Colon or Rectal Cancer Other type of Cancer: Please list_______________

Mental Problem (depression, bipolar, schizophrenia)

Alcohol or Drug Problem Other diseases that run in your family: Please list ____________________ _____ _________________________ _________________________

___ ___ ___

_____________ _____________ _____________

__________ __________ __________

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Q: Based on a health behavior concept, this tool allows us to assess the readiness of other public health programs to integrate genomics:


Q: Based on a health behavior concept, this tool allows us to assess the readiness of other public health programs to integrate genomics:

A: What is the “Genomics Model Process”?

Genomics Model Process

• Adapted from the Transtheoretical Model (TTM) of individual behavior change

• Tailor interventions based on program’s stage

• Stage-appropriate activities

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Q: In addition to assessing how family history information is collected and used in an HMO setting, our project also evaluated this CDC tool, from the providers’ perspective:

Family History & Genetics 200

Q: In addition to assessing how family history information is collected and used in an HMO setting, our project also evaluated this CDC tool, from the providers’ perspective:

A: What is Family HealthwareTM?

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Q: Family history and chronic disease fact sheets adapted from this state have been distributed at multiple health promotion events in Oregon:


Q: Family history and chronic disease fact sheets adapted from this state have been distributed at multiple health promotion events in Oregon:

A: What is Minnesota?

GENOMICS JEOPARDY

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Q: An entire chapter dedicated to Genetics & Family History was included in this state document:


Q: An entire chapter dedicated to Genetics & Family History was included in this state document:

A: What is the Oregon Comprehensive Cancer Plan?

GENOMICS JEOPARDY

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Q: This resource (CD-Summary) for providers, which reviews how to use family history to identify and prevent disease in high-risk populations was distributed to this number of providers in July 2006.


Q: This resource (CD-Summary) for providers, which reviews how to use family history to identify and prevent disease in high-risk populations was distributed to this number of providers in July 2006.

A: What is 18,000 Oregon primary care providers?

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Q: Family History Questions were NOT added to this surveillance system (multiple choice)

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A: What is BRFSS?

B: What is PRAMS2?

C: What is YRBS?

D: What is the General Knowledge Survey?

D: What is YRBS?


GENOMICS JEOPARDY


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Q: This Oregon public health program had already included family history questions on the BRFSS even before the CDC Genomics Grant existed:


Q: This Oregon public health program had already included family history questions on the BRFSS even before the CDC Genomics Grant existed:

A: What is the Oregon Diabetes Program?

GENOMICS JEOPARDY

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Q: This project, which examined data from clinical genetics centers to determine how many patients traveled more than 80 miles for genetic services, used this technology:


Q: This project, which examined data from clinical genetics centers to determine how many patients traveled more than 80 miles for genetic services, used this technology:

A: What is a GIS?

Outside of Portland Eugene, & Bend

Population 2004

545,101

% of Population

15%

# of Genetics Patients

2006

155

% of all Genetics Patients seen in Oregon

4%

Outside of Portland Eugene, & Bend

Population 2004

545,101

Percent of Population

15%

# of Cancer Genetics Patients

2006

17

% of all Cancer Genetics Patients seen in Oregon

3%

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Q: Similar to the project in Michigan, this analysis focused on early on-set cases of this condition:


Q: Similar to the project in Michigan, this analysis focused on early on-set cases of this condition:

A: What is cancer?

Early Age of Diagnosis: Limited list of invasive cancers, Oregon 1996-2004

Total Cancer Cases % of total that are early onset (< 50 years)

Total 81,312 10.74%

Stomach 1,882 10.04%

Colon 11,478 6.19%

rectum 4,293 10.23%

other GI 3,061 14.73%

Pancreas 3,402 5.64%

Breast 24,106 19.48%

Ovary 2,651 20.60%

Uterine/endometrial 4,176 13.07%

Prostate 22,631 1.87%

Kidney and renal pelvis 3,632 14.79%

GENOMICS JEOPARDY

FINAL JEOPARDY

Q: In an average week, the number of unique visitors going to www.healthoregon.org/genetics:

A: What is 600?

SuccessesOregon Genetics Program

• Genomics integration into public health: – Diabetes– Cancer (multiple partnerships)

• Surveillance– Diabetes– Heart disease– Colorectal cancer

• Publications– Diabetes– Obesity

• Provider activities– Kaiser Family History Project– FQHC Project– Education

Accomplishments & Outcomes: Genomics Successes in Oregon Amy Zlot Oregon Genetics Program.

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Transcript of Accomplishments & Outcomes: Genomics Successes in Oregon Amy Zlot Oregon Genetics Program.