About - Quatrefolic · About XaQuil ™XR is an innovative medical food formulated with Quatrefolic...

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About XaQuil XR is an innovative medical food formulated with Quatrefolic ® where the release of the active ingredients is tightly controlled for an optimization of the blood levels of 5-MTHF and can be used as an adjunctive treatment for depression. XaQuil XR may constitute an effective, safe, and well tolerated medical food strategy for patients with major depressive disorder who have a partial response or no response to SSRIs (Selective Serotonin Reuptake Inhibitors). In XaQuil XR Quatrefolic ® provides folate in the already biologically active form of 5-methyltetrahydrofolate, without any kind of metabolization. 5- MTHF can reach the systemic circulation and cross the blood-brain barrier, and enter straight the brain cell, for direct utilization in the folate cycle. Gnosis and XYMOGEN have been working together to develop an unique extended release formulation in tablets with specific release profile of the active ingredient useful to increase the folate levels. The XaQuil XR formulation allows a time dependent release of the 5- MTHF in the gastroenteric system, followed by a time-dependent release of the active in the plasma. Extended-release of 5-MTHF may be crucial in partial response or no response subjects to SSRIs because normalizes the blood folate level and maximizes efficacy of XaQuil XR. XaQuil XR. extended-release coating technology is property of Gnosis S.p.A (International Application PCT/IB2014/065852). A b o u t X Y M O G E N XYMOGEN, a family-owned, health sciences company headquartered in Orlando, Fla., has been providing high-quality dietary supplements to licensed healthcare practitioners for more than a quarter century. The nutraceutical company has introduced numerous innovations to the functional medicine community; its Medical Board of Advisors consists of clinical practitioners who represent a broad range of specialties.

Transcript of About - Quatrefolic · About XaQuil ™XR is an innovative medical food formulated with Quatrefolic...

Page 1: About - Quatrefolic · About XaQuil ™XR is an innovative medical food formulated with Quatrefolic ® where the release of the active ingredients is tightly controlled for an optimization

About

XaQuil™XR is an innovative medical food formulated with Quatrefolic® where the release of the active ingredients is tightly controlled for an optimization of the blood levels of 5-MTHF and can be used as an adjunctive treatment for depression. XaQuil™XR may constitute an effective, safe, and well tolerated medical food strategy for patients with major depressive disorder who have a partial response or no response to SSRIs (Selective Serotonin Reuptake Inhibitors).

In XaQuil™XR Quatrefolic® provides folate in the already biologically active form of 5-methyltetrahydrofolate, without any kind of metabolization. 5- MTHF can reach the systemic circulation and cross the blood-brain barrier, and enter straight the brain cell, for direct utilization in the folate cycle.

Gnosis and XYMOGEN have been working together to develop an unique extended release formulation in tablets with specific release profile of the active ingredient useful to increase the folate levels. The XaQuil™XR formulation allows a time dependent release of the 5- MTHF in the gastroenteric system, followed by a time-dependent release of the active in the plasma. Extended-release of 5-MTHF may be crucial in partial response or no response subjects to SSRIs because normalizes the blood folate level and maximizes efficacy of XaQuil™XR.

XaQuil™XR. extended-release coating technology is property of Gnosis S.p.A (International Application PCT/IB2014/065852).

About XYMOGEN

XYMOGEN, a family-owned, health sciences company headquartered in Orlando, Fla., has been providing high-quality dietary supplements to licensed healthcare practitioners for more than a quarter century. The nutraceutical company has introduced numerous innovations to the functional medicine community; its Medical Board of Advisors consists of clinical practitioners who represent a broad range of specialties.