ABOUT

Our conferences are designed with our sponsors and exhibitors in mind: we create intimate and highly interactive environments so that they can maximize their reach and make long-lasting contacts. Our sponsors and exhibitors benefit from a few of the following:

• Sponsors/exhibitors have the option to receive the delegate list a week before and a week after the conference.

• The exhibit space for the meeting is shared with any other concurrent conferences, providing sponsors and exhibitors with access to a larger audience. The exhibit space is also where all networking functions take place, including coffee, snack stations, breakfast, and the evening reception.

• Your corporate logo will be placed on the cover page of the conference brochures, the proceedings given to all conference delegates, and on the presentation screen during all breaks to enhance your company’s visibility at the event. Your logo will also be placed on the conference website agenda linked to your website.

SPONSORSHIP OPPORTUNITIES

We invite you to attend the Molecular Diagnostics Summit, which takes place July 6 - 8, 2016 in Boston, MA. The summit will bring together our usual balance of industry and academia, so that delegates have the unique opportunity to network with colleagues from different sectors and gain a fresh perspective on the various topics below:

2nd Cancer Markers & Liquid Biopsies (Jul 6-7) - The role of cancer markers is significant towards the diagnosis, prognosis, and surveillance of a patient. Understanding markers and characterizing circulating elements with the latest technologies aid our progress toward the future of better personalized cancer care. Leaders in industry and academia will discuss platforms for iso-lating and studying CTCs. This meeting will also discuss biomarker sensitivity, stability, validation, and how we can use markers to follow up with patients and improve the quality of life.

Digital PCR & qPCR (Jul 6-7) -There has been a push to find a faster and a more efficient way to optimize the quantification of nucleic acids. In the past, quantitative polymerase chain reaction (qPCR) has been the best way to measure the relative ampli-fication of PCR in real time. In more recent years, digital PCR has become a newer method of PCR quantification that can result in absolute quantification, increased sensitivity in samples, more controllable precision, and multiple partitions of the same sample. This meeting will discuss the newest developments in digital PCR and qPCR in relation to how PCR can be used the molecular diagnostics field.

Precision Medicine (Jul 7-8) - There is a huge drive in Precision Medicine as it integrates research and clinical practice to build a knowledge base that can better guide individualized patient care. At a crucial time, where there are efforts to scale up population-based genome sequencing and integrate it with clinical data, this meeting will discuss the progress towards the implementation of precision medicine. This conference will discuss the future of healthcare, strategies and technologies for successful implementation, precision medicine beyond oncology, integrating and interpreting personal genomics, big data, bioinformatics, and overcoming challenges in the commercialization of precision medicine.

If you are interested in participating in the Summit’s poster session to showcase your work and research, please submit an abstract here and select which conference you would like to present in by June 6, 2016. In addition, the top two to three abstracts submitted for each individual conference will be selected to give a short oral presentation as part of that conference’s program. Presentation slots fill up fast so please submit your abstract ASAP.

POSTER & ORAL PRESENTATION OPPORTUNITIES

For sponsorship and exhibit opportunities, please contact:Amber Kempf

Senior Account Executiveamber.kempf@gtcbio.com

Nicolas RodriguezAccount Executive

nicolas.rodriguez@gtcbio.com

SPONSORS

GOLD

CORPORATE

Viracor-IBT is a CAP/CLIA accredited laboratory providing large molecule biomarker support for phase I-IV trials. Viracor-IBT has 30+ years of experience in molecular testing, immune response monitoring, allergy/hypersensitivity testing. Expertise includes custom assay design, optimization, transfer and validation. Our streamlined processes provide more options and flexibility for your specific needs.

PGDx advances the frontiers of cancer medicine through innovative genomic technologies for oncology researchers, drug developers, clinicians and patients. PGDx is working toward broad patient access, through both CLIA-certified facility providing comprehensive genomic services, and a technology transfer solution enabling molecular laboratories to easily internalize testing. Co-founders Luis Diaz, MD, and Victor Velculescu, MD, PhD, are recognized leaders in cancer genomics with extensive experience in advanced genomic technologies to research, drug development and clinical practice.

Using novel epigenetic technology, Epiontis provides precise and reproducible immunomonitoring services for clinical trials. The epigenetic PCR tests are based on in-house developed and IP protected markers specific for immune cell types (Treg, Th17, overall Tcells, etc.). Frozen whole blood or tissue can be used, permitting easy storage and logistics.

MEDIA PARTNERS

Foundation Medicine (NASDAQ:FMI) is a molecular information company dedicated to a transformation in cancer care in which treatment is informed by a deep understanding of the genomic changes that contribute to each patient’s unique cancer. The company’s clinical assays, FoundationOne® for solid tumors and FoundationOne® Heme for hematologic malignancies and sarcomas, provide a comprehensive genomic profile to identify the molecular alterations in a patient’s cancer and match them with relevant targeted therapies and clinical trials. Foundation Medicine’s molecular information platform aims to improve day-to-day care for patients by serving the needs of clinicians, academic researchers and drug developers to help advance the science of molecular medicine in cancer.

Keynote

Helmy Eltoukhy Guardant Health

Session:Isolation, Characterization, & Diagnostic applications of

CTCs

Session:Isolation, Characterization, & Diagnostic applications of

CTCs (cont.)

Session:Advances in the Clinical Application of Circulating Nucleic

Acid

Session:Validation & Application of Cancer Specific Markers

Session:Current Progress in Exosome Applications

Session: Clinical & Biological Challenges in Liquid Biopsy

Session:Novel Uses of Digital PCR

Session:Data Analysis and Reproducible Research

Session:Validation & Standardization: Optimization of PCR

Session:Detection & Quantification of Nucleic Acids

Session:qPCR in Diagnostics

Session:qPCR in Diagnostics

AGENDA AT-A-GLANCE

Day 1 - Wednesday, July 6, 2016

7:007:55

8:00

10:00

10:30

12:10

1:10

3:15

3:45

6:15

7:00

8:00

10:00

10:35

1:00

Registration & Continental BreakfastWelcome & Opening Remarks

Digital PCR & qPCR2nd Cancer Markers & Liquid Biopsies

Day 2 - Thursday, July 7, 2016

Continental Breakfast

All times are approximate and subject to changes without notice

Morning Networking Break

Morning Networking Break

Lunch Provided by GTCbio

Afternoon Networking Break

Evening Reception & Poster Session

Digital PCR & qPCR2nd Cancer Markers & Liquid Biopsies

Conferences Conclude

Session:Overcoming Challenges in the Commercialization of Precision Medicine

Session: Implementation of Precision Medicine: Strategies & Technologies

Session: Implementation of Precision Medicine: Strategies & Technologies

Session:Precision Medicine Beyond Oncology

Session:Integrating & Interpreting Personal Genomics, Big Data, & Bioinformatics

Session:Incentivizing Precision Medicine: Regulation & Reimbursement

AGENDA AT-A-GLANCE

Day 2 - Thursday, July 7, 2016

1:00

2:00

4:05

4:35

5:55

7:00

8:00

10:00

10:40

11:55

1:00

3:05

3:35

5:15

Registration

Precision Medicine

Day 3 - Friday, July 8, 2016

Continental Breakfast

All times are approximate and subject to changes without notice

Afternoon Networking Break

Evening Reception & Poster Session

Morning Networking Break

Precision Medicine

Lunch Provided by GTCbio

Conferences Conclude

Afternoon Networking Break

Farideh BischoffSilicon Biosystems

Agnieszka BroniszBrigham and Women’s Hospital

Carlos Cordon-CardoMount Sinai School of Medicine

Z Hugh FanUniversity of Florida

Sandra GastonTufts Medical Center

Giulio GenoveseBroad Institute

Chwee Teck LimNational University of Singapore

Quan LuHarvard School of Public Health

Jun LuoJohns Hopkins Hospital

John MartignettiIcahn School of Medicine at Mount Sinai

Stuart MartinUniversity of Maryland

Irina Matei Weill-Cornell Medical College

For an updated speaker list visit: www.gtcbio.com/molecular/speakers

DISTINGUISHED SPEAKERSOvercoming the Challenges of Heterogeneous Liquid Biopsies Through Precise Image-based Single-cell Sorting

Extracellular Vesicles and Intra-tumoral Heterogeneity of Glioblastoma

CTC Isolation Methods and Clinical Applications

2nd Cancer Markers & Liquid Biopsies

Session: Clinical & Biological Challenges in Liquid Biopsy

Session: Validation & Application of Cancer Specific Markers

KEYNOTE SPEAKER

From Wired to Wireless: The Guardant Experience with 20,000+ Clinical Liquid Biopsies

Mechanism and Therapeutic Application of ARRDC1-mediated Microvesicles (ARMMs)

Session: Advances in the Clinical Application of Circulating Nucleic Acid

Novel Microfluidic Device to Rapidly Test Patient Tumor Cells for Cytoskeletal Drug Responses

Treatment Selection in Prostate Cancer: Exploring the Full Potential of Liquid Biopsies

Helmy EltoukhyGuardant Health

Clonal Expansions in Blood and the Risk of Hematological Malignancies

Tumor-derived Exosomes and Their Promise as Diagnostic and Predictive Biomarkers

Microfluidics for the Single Cell Analysis of Circulating Tumor Cells

Paraskevi GiannakakouWeill-Cornell Medical College

Michael HellerUniversity of California San Diego

Chris KarlovichClovis Oncology

Roya Khosravi-FarBeth Israel Deaconess Medical Center

Keith KnutsonMayo Clinic

Rebecca LearyNovartis Institutes for Biomedical Research

Towia LibermannBeth Israel Deaconess Medical Center

Johan Skog Exosome Diagnostics

Sherilyn SawyerBrigham and Women’s Hospital

Phil StephensFoundation Medicine

Bakhos TannousMassachusetts General Hospital

Yaoyu WangDana-Farber Cancer Institute

Robert WeinbergMassachusetts Institute of Technology

Yong ZengUniversity of Kansas

For an updated speaker list visit: www.gtcbio.com/molecular/speakers

DISTINGUISHED SPEAKERSDrug-Target Engagement in CTCs: From Mechanism to Clinical Application in Prostate Cancer

Rapid Isolation and Detection of Circulating Cell Free DNA, RNA and Exosome Biomarkers for Liquid Biopsy Cancer Diagnostics

Early Detection of Pancreatic Cancer Using a New 5-gene Classifier

2nd Cancer Markers & Liquid Biopsies

Soluble Innate and Adaptive Immune System Mediators as Biomarkers for Diagnosis, Prognosis and Response to Therapy in Cancer

Molecular Assessment of Biofluid Biopsies from NSCLC Patients Treated with Rociletinib

Session: Current Progress in Exosome Applications

Session: Clinical & Biological Challenges in Liquid Biopsy

Tumor-Educated Platelets: A Novel Platform for Blood-Based Pan-Cancer, Multi Class and Molecular Pathway Cancer Diagnostics

Challenges of ctDNA Diagnostics for Patients with Cancer

Characterizing the Cancer Genome from the Circulation

Standardizing Extracellular Small RNASeq for Biomarker Discovery

Session: Advances in the Clinical Application of Circulating Nucleic Acid

Mechanisms of Malignant Progression of Carcinomas

Microfluidic Analysis of Circulating Exosomes Toward Non-Invasive Cancer Diagnosis

Ramana DavuluriNorthwestern University - Feinberg School of Medicine

Jarrod DeanSanofi

Hatice DuzkaleChildren’s Hospital Medical Center

Manuela HofnerAIT Austrian Institute of Technology

Pierre Laurent-PuigDescartes University

Preveen RamamoorthyStrand Life Sciences

Kenneth PierceBrandeis University

Rashmi Kanagal ShamannaMD Anderson Cancer Center

Chen SongDana-Farber Cancer Institute, Harvard Medical School

Dejan StebihNational Institute of Biology

Jennifer TaylorRTI International

Joel TellinghuisenVanderbilt University

Alexander UrbanStanford University

James WilleyUniversity of Toledo College of Medicine

For an updated speaker list visit: www.gtcbio.com/molecular/speakers

DISTINGUISHED SPEAKERS

Session: Data Analysis and Reproducible Research

Applications of qPCR in Next-Gen Sequencing

Digital PCR & qPCR

Session: Novel Uses of Digital PCR

Development of Multi-Target ddPCR Methods for Detection of Genetically Modified Organisms

Session: qPCR in Diagnostics

Session: qPCR in Diagnostics

Session: Validation & Standardization: Optimization of PCR

Microfluidics-Based qPCR, a Versatile Tool for Biomarker Analysis: From MSRE-Based qPCR to High-Throughput Multiplex Immunoassay

Novel Mutation Enrichment Approaches for Increasing Sensitivity and Specificity of Molecular Diagnostics Assays

PCR Strategies for Identifying Multiple Bacterial Species Using a Closed-Tube Assay

Using Digital PCR in Newborn Screening to Characterize Calibrators and Reference Materials for Quantitative Molecular Assays

Using Least Squares to Design Better qPCR Analysis Protocols

Comparing Drop Digital PCR to Quantitative PCR: Evolving the Gene Therapy Viral Vector Analytical Paradigm

Session: Novel Uses of Digital PCR

Precision Medicine

Gil AlterovitzHarvard Medical School

Kristine Ashcraft Genelex

Keith F. BatchelderGenomic Healthcare Strategies

Thomas BrownSwedish Cancer Institute

Kenneth J BloomHuman Longevity

Pieter R. CullisUniversity of British Columbia

Martin DawesThe University of British Columbia

Hans LehrachMax Planck Institute for Molecular Genetics

Christine LuHarvard Medical School & Harvard Pilgrim Health Care Institute

John Mattison Kaiser Permanente

Jen MadsenArnold & Porter

Iain MillerHealthcare Strategies Group; NICE; European Personalized Medicine Association

Liz MilwardThe University of Newcastle Australia

Ken RamosArizona Health Sciences Center

DISTINGUISHED SPEAKERS

Pharmacogenetic Testing and Medication Decision Support in Primary Care

Regulation & Reimbursement: Access to Precision Medicine Products

The Federal Government Innovates, Too: Changes in the Regulatory & Reimbursement Framework

Session: Incentivizing Precision Medicine: Regulation & Reimbursement

Session: Integrating & Interpreting Personal Genomics, Big Data, & Informatics

Session: Integrating & Interpreting Personal Genomics, Big Data, & Informatics

Bringing Diagnostics to Market

Introducing Molecular Medicine into the Population: The Personalized Medicine Initiative

Session: Integrating & Interpreting Personal Genomics, Big Data, & Informatics

For an updated speaker list visit: www.gtcbio.com/molecular/speakers

The Future of Translational and Clinical Genomics in Precision Medicine

The Emerging Commercial Paradigm for Precision Medicine and Companion Diagnostics: Market Access & Recent Global Developments

Session: Precision Medicine Beyond Oncology

Integration and Outcomes: Shifting Precision Medicine from the Future to Now

Session: Integrating & Interpreting Personal Genomics, Big Data, & Informatics

Lynn DresslerMission Health

Yasuhiro FunahashiEisai

Patricia GoedeXIFIN

Peter GroenenActelion Pharmaceuticals

Susan HagerFoundation Medicine

Laura HousmanTufts University School of MedicineMolecular Health

Precision Medicine in the Information Age

Session: Precision Medicine Beyond Oncology

Developing a Personalized Medicine Program in a Community Health System: The Mission Health Experience

Leonardo Rodrigues Berg Pharma

David Roth University of Pennsylvania

Mark TrusheimMIT Sloan School of Management

Rina WolfXIFIN

Diane Wuest GNS Healthcare

Precision Medicine

DISTINGUISHED SPEAKERS (cont.)

Session: Incentivizing Precision Medicine: Regulation & Reimbursement

Next-generation Precision Medicine, Are We There Yet?

Implementing Precision Medicine: Diagnosis and Treatment of Lung Cancer

Implementing Precision Medicine, Determining Economic Value Under Adaptive Biomedical Innovation Pathways

Session: Integrating & Interpreting Personal Genomics, Big Data, & Informatics

Session: Precision Medicine Beyond Oncology

Session: Implementation of Precision Medicine: Strategies & Technologies

For an updated speaker list visit: www.gtcbio.com/molecular/speakers

Session: Implementation of Precision Medicine: Strategies & Technologies