AARHUS UNIVERSITY Partikel terapi accelerator (Siemens)

Cancer and radiation therapySøren Pape Møller

23 NOVEMBER, 2009AARHUSUNIVERSITY

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Partikel terapi accelerator (Siemens)



Dose and intensity

• Range of 30 cm →• Proton energy: (50-)250 MeV• Carbon energy: (100-)430 MeV/u=5GeV

• Dose of 2 Gy (=J/kg) in 2(10) l in 2 min. →• Particle intensity 6⋅1011 p in 2 min• or 2⋅1010 C in 2 min



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SIEMENS/DANFYSIK PT system

10m



PT RKASiemens facility in Marburg

Siemens: Also PT iKiel and Shanghai



Kiel facility

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6

Rhön-Klinikum Marburg



Rhön-Klinikum Marburg

7First accelerator installation in nov. 2008



Building Layout

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Proton energy range 48-250 MeV/u

Carbon ion energy range 88-430 MeV/u

Time to change between ion species <10 s

Ramping time of synchrotron to highest magnetic field <1 s

Extraction time from synchrotron <10 s (up to 30 s)

Time for energy change (stop extraction to start extraction) <5 s

Time to switch beam from room to room <8 s

System uptime >95-98%

Maximum number of protons at end of HEBT per spill 4⋅1010

Maximum number of carbon ions at end of HEBT per spill 1⋅109

Intensity variation 0.001-1

Stability during spill

Extracted intensity (300 ms) sampling <+30%/-50%

Max/min intensity for faster sampling (down to 10 µs) <3

Beam width at variations at isocenter <20%

Position variations at isocenter (including feedback) <0.5 mm

Integral intensity (fill) <30%

Variations in mean energy from synchrotron <0.1%

Main specs. to the PT accelerator system



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10 m

RKA i Marburg

Ion source

Low-energypreaccelerator

RadioFrequencyQuadrupole

Linac

Focusingquadrupole

Deflectionmagnet



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ECR Ion Source



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13

Beam after ion source



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LEBT

•Macro-pulse chopper



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Solenoide



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LINAC quadrupoles

Ramped lenses with 5Hz

15ms ramp-up-time, 3ms flat-top, 25ms ramp-down-time



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Radial Envelopes

0 100 200 300 400 500 600

-5

0

5

radi

al e

nvel

opes

x a

nd y

[mm

]

z[cm] beamaxis

-35° -35° -35°0° 0° 0°

L L



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MEBT

Vertical correctors

chopper

Injection septum

Stripper foil

debuncher



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MEBTHorizontal beam envelope [m] versus distance [m]

Vertical beam envelope [m] versus distance [m]

Note: Linear optics

0.000

0.000

14.574

14.574

0.025000

0.025000

-0.025000

-0.025000

Betatron envelope Momentum envelope



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Chopper

slit

bend chop bend



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Charge separation

The most closely spaced ions, from a not complete stripping process, will be O7+ and O8+.



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MEBT 25° dipole



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Debuncher

Beam at the stripper:

After the debuncher:



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10 m

RKA i Marburg

Synchrotron cavity2.5 kV, 1-7 MHz, Rev. freq. 0.5-3.5 MHz



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DF synchrotron

Bumper

Elektrostatiskinjektions

Elektrostatiskekstraktionsseptum

Magnetiskekstraktiosepta



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Synchrotron dipole



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Synchrotron sextupole



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Non-linear EFB variation, Pre-prototype exit, y=0, 100%

-0.00100

-0.00080

-0.00060

-0.00040

-0.00020

0.00000

0.00020

0.00040

0.00060

0.00080

0.00100

-100 -80 -60 -40 -20 0 20 40 60 80 100

x (mm)

dLre

s/Lh

alf (

T)

dLres/LhalfdInt_Rel Calculated

Maximum field, Pre-prototype exit, y=0, 100%

-0.00500

-0.00400

-0.00300

-0.00200

-0.00100

0.00000

0.00100

0.00200

0.00300

0.00400

0.00500

-100 -80 -60 -40 -20 0 20 40 60 80 100

x (mm)

dB0/

B0

(T)

dB0/B0dB/B0 Calculate



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Electrostatic injection septum



Electrostatic extraction Septum

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Multi-Turn-Injection



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Magnetic extraction septum



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Extraction straight section



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Synchrotron cycle

•0

•0,2

•0,4

•0,6

•0,8

•1

•1,2

•0 •1 •2 •3 •4 •5 •6 •7

•time (s)

•B/B

max

•low-energy protons•high-energy protons•low-energy carbon•high-energy carbon

•"chimney"

•dB•/•dt•/•Bmax •=1/s

•Extraction•1-10s

•Injection



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Beam envelope at injection



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Injection bump

Bumper magnet #1 #2 #33.2 mrad. 6.3 mrad. 7.6 mrad.

septum



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Bumper supply

time

Magnetic field

18 μs

Turn 4 15



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Synchrotron dump

Vertical beam envelope [m] versus distance [m]

Note: Linear optics

11.220 18.422

0.040000

-0.040000

Betatron envelope Momentum envelope

Note: Linear optics

0.000 64.800

0.025000

-0.025000



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Slow Extraction



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HEBT



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HEBT

Survey-Plot [mm] 108000

HC

HS1

HC

VS1

HC

HS2

HC

VS2

HC

PG

1

HC

HS3

HC

HS4

HC

VS4

HC

PG

2

HC

PG

3

HC

HS

5

HC

VS

5H

CP

G4

H1PGT

H2PGT

H3PGT

H4H

S1

H4V

S1

H4H

S2

H4V

S2

H4P

G2

H4HS3

H4VS3

H4PGT



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Fast Beam Abort System



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HEBT



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HEBT quadrupole



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TR-1

TR-2

TR-3

TR-4

10 m

RKA i Marburg



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AARHUS UNIVERSITY Partikel terapi accelerator (Siemens)

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