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1 AACPDM Pre-Conference Workshop New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process WEDNESDAY, OCTOBER 16, 2013 | 1:00PM –5:00PM 1:00 – 1:15 (15 min) Welcome & Introduction Current clinic and mobility technology Gerald Harris, PhD, PE Adam Graf, MS 1:15 – 1:25 (10 min) Upper extremity systems and models, instrumentation and assessment Brooke Slavens, PhD Alyssa Schnorenberg, MS 1:25 – 1:45 (20 min) Upper extremity assisted-gait clinical application and results Lofstrand Crutch mobility Anterior/posterior walker mobility Brooke Slavens, PhD Alyssa Schnorenberg, MS 1:45 – 2:10 (25 min) Upper Extremity wheelchair clinical application and results Larry Vogel, MD Brooke Slavens, PhD Alyssa Schnorenberg, MS 2:10 – 2:20 (10 min) Musculoskeletal modeling and simulation using OpenSim, SIMM, and EMG for quantitative upper extremity assessment. Brooke Slavens, PhD 2:20 – 2:30 (10 min) Questions 2:30 – 2:50 (20 min) Assessment with Microsoft Kinect SHUEE - Orientation/Application Demonstration Susan Riedel, SM, PE Jacob Rammer, BS Joseph Krzak, PhD, PT, PCS 2:50 – 2:55 (5 min) Questions

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

WEDNESDAY, OCTOBER 16, 2013 | 1:00PM –5:00PM

1:00 – 1:15 (15 min) Welcome & Introduction

Current clinic and mobility technology

Gerald Harris, PhD, PE

Adam Graf, MS

1:15 – 1:25 (10 min) Upper extremity systems and models, instrumentation and assessment

Brooke Slavens, PhD

Alyssa Schnorenberg, MS

1:25 – 1:45 (20 min) Upper extremity assisted-gait clinical application and results

Lofstrand Crutch mobility

Anterior/posterior walker mobility

Brooke Slavens, PhD

Alyssa Schnorenberg, MS

1:45 – 2:10 (25 min) Upper Extremity wheelchair clinical application and results

Larry Vogel, MD

Brooke Slavens, PhD

Alyssa Schnorenberg, MS

2:10 – 2:20 (10 min) Musculoskeletal modeling and simulation using OpenSim, SIMM, and EMG for quantitative upper extremity assessment.

Brooke Slavens, PhD

2:20 – 2:30 (10 min) Questions

2:30 – 2:50 (20 min) Assessment with Microsoft Kinect

SHUEE - Orientation/Application

Demonstration

Susan Riedel, SM, PE

Jacob Rammer, BS

Joseph Krzak, PhD, PT, PCS

2:50 – 2:55 (5 min) Questions

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2:55 – 3:10 (15 min) Break and Kinect Open

3:10 – 3:25 (15 min) Lower extremity (LE) motion analysis in Planovalgus and Equinovarus foot deformities. LE modeling concepts for hip, knee, ankle and segmental foot Kinematics.

Gerald Harris, PhD, PE

Peter Smith, MD

3:25 – 3:40 (15 min) Planovalgus foot study Joseph Krzak, PT, PhD

Katie Konop, MS

3:40 – 3:55 (15 min) Equinovarus foot study Peter Smith, MD

Joseph Krzak PT, PhD

3:55 – 4:00 (5 min) Questions

4:00 – 4:15 (15 min) Dynamic Fluoroscopy Ben McHenry, PhD

Taly Gilat Schmit, PhD

Janelle Cross, MS

4:15 – 4:20 (5 min) Questions

4:20 – 4:30 (10 min) IntelliStretch Robotic System

and Application

Deborah Gaebler-Spira, MD

Li-Qun Zhang, PhD

4:30 – 4:50 (20 min) IntelliStretch Demonstration Deborah Gaebler-Spira, MD

Li-Qun Zhang, PhD

4:50 – 4:55 (5 min) Questions

4:55 – 5:00 (5 min) Closure & Contacts Gerald Harris, PhD, PE

30 Minute Post-Workshop Hands On/Operation of Sample Devices: IntelliStretch and Kinect.

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

WELCOME AND INTRODUCTION

Speaker: Gerald F. Harris, Ph.D., P.E.

E-mail: [email protected]

Objective: This course is designed to explore emerging clinical applications resulting from advances in

mobility assessment and assisted therapy. These research driven applications integrate clinical need

with novel technologies to offer more effective methods of mobility analysis and therapeutic treatment.

Course Summary: This course will provide significant exposure to emerging applications in human

motion analysis and robotic assisted movement therapy. The research driven symposium will offer a

balanced presentation of upper and lower extremity motion analysis applications which employ

advanced modeling techniques and technologies to improve pre-treatment assessment and post-

treatment follow-up. The upper extremity applications will address the internal joint demands of

children and young adults who use anterior and posterior walkers, Lofstrand (Canadian) crutches, and

manual wheelchairs. The lower extremity applications will address the segmental motion demands of

the hindfoot, forefoot and hallux in children with equinovarus and planovalgus foot deformities who

are candidates for both conservative and surgical care. Novel fluoroscopic technology will be discussed

which allows in vivo examination of the talocrural and subtalar joints during walking while shod and with

orthotics. An application example of robotic assisted movement therapy will be presented in terms of

setting subject-specific goals which can be modified throughout the progression of treatment. The

importance of integrated gaming strategies for upper extremity assessment and therapy with a

markerless system will be presented and demonstrated. A 30 minute hands on opportunity will follow

the presentations and demonstrations.

Learning Objectives:

At the end of the symposium participants will be able to discuss:

1) how recent research is advancing our understanding of upper extremity mobility and the longer

term implications of assistive device use in children

2) how recent research is advancing our understanding of segmental foot motion and how this

knowledge is being used to make better clinical decisions

3) how novel fluoroscopic imaging of the hindfoot is increasing our knowledge of bony hindfoot

dynamics and the potential for future clinical application

4) important features of robotic assisted movement therapy and how this technology can be useful

in the clinician’s treatment arena

5) how gaming strategies are integrated with therapy demands in the current clinical environment

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

CURRENT CLINIC AND MOBILITY TECHNOLOGY

Speaker: Adam Graf, M.S. E-mail: [email protected] Learning Objective: Important features of robotic assisted movement therapy and how this technology can be useful in the clinician’s treatment arena. Presentation Summary: This is an overview of available technology used to assess mobility and assist with therapy in a clinical setting. The equipment will primarily be involved with the assessment and assistance for the following categories that represent functional ability:

Joint Range of Motion (ROM)

Strength

Gait

Posture

Ability to Perform Activities of Daily Living

Assessment of:

o ROM

Smartphone Apps

Wearable Sensors/Inertial Sensors

2D Motion Detection/Video Systems

3D Motion Capture Systems

Fluoroscopy

o Strength

Hand Held Dynamometry

Computerized Dynamometry

Instrumented Devices Using Force Transducers (Walkers, Crutches, Wheelchairs,

etc.)

Electromyography (EMG) Sensors

o Gait

2D Video Systems

3D Gait Analysis Systems

Pressure Mapping

Wearable Sensors/Inertial Sensors

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

CURRENT CLINIC AND MOBILITY TECHNOLOGY

o Posture

Computerized Dynamic Posturography

6 Axis Force Platforms

o Activities of Daily Living

SHUEE

AHA

Technology Used to Assist in Therapy:

o Mobility Assistance

Walk Aide – for foot drop

Dynamic Assistive Orthotics

Exoskeleton

Push Activated Power Assist Wheels and Powered Wheelchairs

Lokomat and Assistive Treadmills

o Interactive Gaming

Gamecycle

o Biofeedback

o Functional Electrical Stimulation (FES)

o Virtual Reality

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AACPDM Pre-Conference Workshop New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

PEDIATRIC ASSISTED MOBILITY: UPPER EXTREMITY BIOMECHANICS AND MODELING Speakers: Brooke Slavens, PhD, Lawrence Vogel, MD, Alyssa Schnorenberg, MS

E-mail: [email protected], [email protected], [email protected]

Learning Objective: How recent research is advancing our understanding of upper extremity mobility and the longer term implications of assistive device use in children. This session will begin with an overview of the mobility needs in youth with SCI, SB, OI, and CP, and

the incidence of upper extremity pain in those with SCI. This will be followed by a discussion of

biomechanical modeling and advanced evaluation in the motion analysis lab of upper extremity

movement during manual wheelchair propulsion and use of assistive devices during walking.

______________________________________________________________________________

Throughout the lifespan of individuals with disabilities, mobility is essential for mastery in all

aspects of their lives. Mobility is one of the main vehicles by which individuals explore their world

from their home, neighborhood and community and is critical to full participation and life satisfaction.

Therefore it is critical that for individuals with mobility impairments, such as those with spinal cord

injuries (SCI), spina bifida (SB), osteogenesis imperfecta (OI), or cerebral palsy (CP),that they maintain

efficient modes of mobility throughout their lives.

Because individuals with mobility impairments are susceptible to over-use syndromes and

premature aging as manifested by upper extremity pain and degenerative arthritis, preventative

efforts are needed to preserve upper extremity function and reduce upper extremity pathology and

associated pain. A major contributing factor to upper extremity pathology is excessive forces applied

to the upper extremity during transfers, propulsion of manual wheelchairs and use of assistive devices.

The standard practice of rehabilitation of youth with mobility impairments includes instruction

in the proper techniques of transferring, wheelchair propulsion and use of assistive devices. Despite

these efforts, the high incidence of upper extremity pain in those with mobility impairment indicates

that additional efforts are needed.

Interventions to preserve upper extremity function and reduce pain must continuously meet

the evolving needs of youth as they grow and their modes of mobility change. Use of biomedical

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techniques of evaluating upper extremity function can substantially supplement clinical interventions

by more thoroughly identifying joint movement and stresses during activities such as manual

wheelchair propulsion and ambulation with assistive devices.

References 1. Vogel, L.C., Krajci K.A., Anderson, CJ. Adults with pediatric-onset spinal cord injuries. Part 2:

Musculoskeletal and neurological complications. J Spinal Cord Med, 2002; 25:117-123. 2. Vogel, L.C., Krajci K.A., Anderson, CJ. Adults with pediatric-onset spinal cord injuries: Part 3: Impact

of medical complications. J Spinal Cord Med, 2002; 25:297-305. 3. Vogel LC, Zebracki K, Chlan KM, Anderson CJ. Long-term outcomes of adults with pediatric-onset

spinal cord injuries as a function of neurological impairment. J Spinal Cord Med 2011; 34:60-66. 4. Ballinger DA, Rintala DH, Hart KA. The relation of shoulder pain and range-of-motion problems to

functional limitations, disability, and perceived health of men with spinal cord injury: a multifaceted longitudinal study. Arch Phys Med Rehabil 2000; 81:1575–81.

5. Boninger ML,Towers JD, Cooper RA, Dicianno BE, MuninMC. Shoulder imaging abnormalities in individuals with paraplegia. J Rehabil R&D 2001; 38:401–8.

6. Subbarao JV, Klopfstein J, Turpin R. Prevalence and impact of wrist and shoulder pain in patients with spinal cord injury. J Spinal Cord Med 1994; 18:9–13.

7. Consortium for Spinal Cord Medicine. Preservation of upper limb function following spinal cord injury: a clinical practice guideline for health-care providers. J Spinal Cord Med 2005; 28:433–70.

8. Slavens, BA, Sturm, PF, Bajournaite, R, Harris, GF. Upper extremity dynamics during Lofstrand crutch-assisted gait in children with myelomeningocele. Gait and Posture, 2009; 30(4): 511-517.

9. Slavens, BA, Sturm, PF, Harris, GF. Upper extremity inverse dynamics model for crutch-assisted gait assessment. Journal of Biomechanics, 2010; 43 (10): 2026-2031.

10. Slavens, BA, Bhagchandani, N, Wang, M, Smith, PA, Harris, GF. An upper extremity inverse dynamics model for pediatric Lofstrand crutch-assisted gait. Journal of Biomechanics, 2011; 44:2162-2167.

11. Konop KA, Strifling KMB, Krzak J, Graf A, Harris GF. Upper extremity joint dynamics during walker assisted gait: a quantitative approach towards rehabilitation intervention. J Exp Clin Med. 2011; 3(5):213-17.

12. Konop KA, Strifling KMB, Wang M, Cao K, et al. A biomechanical analysis of upper extremity kinetics in children with cerebral palsy using anterior and posterior walkers. Gait Posture 2009; 30:364-9.

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AACPDM Pre-Conference Workshop New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

ENHANCING UPPER EXTREMITY FUNCTIONAL ASSESSMENT WITH THE KINECT MOTION ANALYSIS SYSTEM Speakers: Joseph Krzak, PhD, PT, PCS, Susan Riedel, SM, PE, Jacob R. Rammer, BS

E-mail: [email protected], [email protected], [email protected]

Learning Objective: How recent research is advancing our understanding of upper extremity mobility and the longer term implications of assistive device use in children. ______________________________________________________________________________

Microsoft Kinect (Kinect) Project Objective: Develop software that detects and records upper extremity kinematics, extracts key measures of upper extremity function, and facilitates scoring of the Shriners Hospitals for Children Upper Extremity Evaluation (SHUEE). Description, Benefits, and Limitations of the SHUEE Clinical Evaluation:

Description: The SHUEE is a clinical assessment tool of upper extremity function for children with hemiplegic cerebral palsy. A video recorded assessment of activities of daily living is scored to provide measures of Spontaneous Function, Dynamic Position, and Grasp/Release. Benefits: The SHUEE offers video-based documentation of functional ability before and after therapeutic or surgical intervention, uses activities relevant to daily life, and provides valuable insight for planning interventions. Limitations: The SHUEE is validated and shows excellent inter-rater and intra-rater reliability [1], but questions have been raised regarding its sensitivity to detect change following intervention. Description, Benefits, and Limitations of the Kinect Motion Analysis System:

Description: The Kinect motion analysis system includes a Microsoft Kinect sensor (depth sensor, images surface map of the body), skeletal tracking and motion recording software (interpolates bone/joint locations and records 3D positions over time), and data processing & interpretation software (calculates/plots angular kinematics, statistics, and SHUEE scores). Benefits: The Kinect system has a very low cost ($100-150) compared to typical clinical motion analysis systems and can be used with any modern Windows PC [2]. It captures motion with reasonable accuracy when compared to a calibrated Vicon system [3]. Its ultraportable design requires a single Kinect sensor and laptop computer, so it can be used outside the traditional clinical environment. Its markerless operation is easy to use and provides increased subject comfort.

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-

Figure 1: Microsoft Kinect (Kinect) System for Kinematic Analysis. The primary user interface (A) allows selection of Kinect (K) activities to launch the data collection application, (B) for hand and (C) for UE activities. Data is then processed in the hand analysis and whole-body analysis MATLAB software, which displays skeletal position (allowing the user to select the start and end of activity cycles to analyze [D]), calculates angular kinematics (position, velocity, acceleration) for all joints and presents the results as kinematic plots, maxima and minima, and activity performance scores for the SHUEE (E). Limitations: Dropout can occur if the Kinect sensor view is occluded by objects or body segments. The current system cannot detect forearm pronation/supination and cannot differentiate shoulder flexion/extension, abduction/adduction, internal/external rotation or wrist flexion/extension and radial/ulnar deviation. The system provides limited hand detection depending on hand position and the presence of obstructions. Pilot Study Preliminary Results and Insights:

Study Protocol: Participants included 16 adolescent subjects ages 12-17 with no current or past impairment of upper extremity function. The SHUEE was performed by the subjects and scored by a P.T, while the Kinect tasks were performed by the subjects and scored by an engineer. Example tasks included throwing a ball, unscrewing a bottle cap, donning and doffing socks and shoes, and cutting

and pulling apart Play-Doh as a food simulation. Key Results: Population normal data allows visual kinematic plotting of future subject performance and development of SHUEE scoring algorithms. The study indicates viability of the Kinect system in clinical motion analysis and as a supplement to the SHUEE in terms of both kinematic output and qualitative ease-of-use observed throughout testing. Observed Limitations: Lack of pronation/supination and wrist and shoulder planar differentiation detection limits parts of the SHUEE. Tracking dropout occurs in certain situations, such as hand detection with a flexed wrist or objects obstructing the Kinect view.

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Future Directions:

Improve system to keep pace with new hardware availability and features (Kinect 2.0).

Detect isolated thumb kinematics and differentiate forearm and wrist movements by plane.

Integrate gaming into the Kinect experience to combine rehabilitation & evaluation.

Expand population to include adults with cerebral palsy and other populations with upper extremity dysfunction.

Key References:

1. Davids, J., Peace, L., Wagner, L., Gidewall, M., Blackhurst, D., and Roberson, M. (2006). Validation of the Shriners Hospital for Children Upper Extremity Evaluation (SHUEE) for Children with Hemiplegic Cerebral Palsy. Journal of Bone and Joint Surgery, 88-A(2), 326-333.

2. Microsoft Corporation. (2013). Kinect for Windows Resources and Documentation. Retrieved from http://www.microsoft.com/en-us/kinectforwindows/develop/resources.aspx

3. Dutta, T. (2012). Evaluation of the Kinect sensor for 3-D kinematic measurement in the workplace. Applied Ergonomics, 43, 645-649.

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

MUSCULOSKELETAL MODELING LOWER EXTREMITY Speakers: Gerald Harris, PhD, PE, Peter Smith, MD

E-mail: [email protected], [email protected]

Learning Objective: How recent research is advancing our understanding of lower extremity mobility and the longer term implications of assistive device use in children. ______________________________________________________________________________ This lower extremity section of the workshop will provide an overview of the clinical need for lower

extremity (LE) motion analysis in children for pre-treatment assessment and post-treatment follow-up

with a focus on the clinical treatment challenges presented by planovalgus and equinovarus foot

deformities. This will be followed by a presentation of fundamental LE modeling concepts for

assessment of hip, knee, ankle and segmental foot kinematics that address the clinical needs.

Pes planovalgus (flatfoot) is a condition characterized by a flattening of the medial longitudinal arch of

the foot, along with hindfoot valgus. Physical observations of flatfoot include low arch structure, rear

foot eversion, medial talar head prominence, altered gait, and calluses [1]. Positive clinical signs for

planovalgus include the "too many toes sign" due to forefoot abduction and positive single limb "heel

rise test" [1], [2]. Clinical gait observation is often used to assess the shape of the footprint, foot

progression angle, calcaneal eversion, heel-to-toe contact, position of the knee, and the presence of a

limp [1], [3]. Quantitative analysis of pes planovalgus beyond the assumption of a single rigid foot

requires the use of segmental biomechanical models.

Equinus and varus, components of equinovarus, are two of the most common foot and ankle

deformities in children with hemiplegic cerebral palsy [4]. Static or dynamic soft tissue imbalance of

the ankle plantarflexors and invertors result in segmental deformities including hindfoot equinus and

inversion, midfoot cavus, as well as, forefoot supination and adduction. These deformities are

ultimately associated with deviations at more proximal segments, increased mechanical work, and

increased energy expenditure during locomotion in children with cerebral palsy [5-7]. Quantitative

gait analysis including multi-segmental foot and ankle kinematics can effectively characterize the

equinovarus deformity during ambulation.

To develop and apply LE models, information acquired by marker sensing systems (typically

optical/video) is used in conjunction with a biomechanical model to determine joint and segmental

kinematics (motion). A virtually limitless number of biomechanical models can be used to calculate

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limb orientation in space, with numerous modeling approaches reported in current literature [8-10].

Anthropometric models use positions of body-mounted markers to calculate the locations of virtual

joint centers based on previously established regression equations. Cluster models rely on groups of

rigidly fixed markers mounted on body segments and require technical-anatomical calibration to

reference anatomical landmarks and segment axes to associated marker clusters. OJC (optimized joint

center) models can be based on a variety of marker placement schemes. The OJC models rely on

calibration trials for an optimized estimate of joint center locus. Collectively these modeling

approaches support the development of customized models specifically tailored to the research study

and/or clinical population of interest.

References 1. E. Harris, J. Vanore, J. Thomas, et al., Diagnosis and treatment of pediatric flatfoot, Journal of Foot

& Ankle Surgery, vol. 43, no. 6, pp. 341–373, Dec. 2004.

2. R. Needleman, Current topic review: subtalar arthroereisis for the correction of flexible flatfoot,

Foot & Ankle International, vol. 26, no. 4, pp. 336–346, Apr. 2005.

3. J. Lee, I. Sung, and J. Yoo, Clinical or radiologic measurements and 3-D gait analysis in children with

pes planus, Pediatrics international : official journal of the Japan Pediatric Society, vol. 51, no. 2,

pp. 201–205, Apr. 2009.

4. T. Wren, S. Rethlefsen, and R. Kay, Prevalence of specific gait abnormalities in children with

cerebral palsy: influence of cerebral palsy subtype, age, and previous surgery. J Pediatr Orthop,

2005. 25(1): p. 79-83.

5. J. Stebbins, et al., Gait compensations caused by foot deformity in cerebral palsy. Gait Posture,

2010. 32(2): p. 226-30.

6. A. van den Hecke, et al., Mechanical work, energetic cost, and gait efficiency in children with

cerebral palsy. J Pediatr Orthop, 2007. 27(6): p. 643-7.

7. L. Ballaz, S. Plamondon, and M. Lemay, Ankle range of motion is key to gait efficiency in

adolescents with cerebral palsy. Clin Biomech (Bristol, Avon), 2010. 25(9): p. 944-8.

8. A. Bell, D. Pedersen, and R. Brand, Prediction of hip joint center location from external markers.,

Human Movement Science, vol. 8, pp. 3-16, 1989.

9. A. Bell, D. Pedersen, and R. Brand, A comparison of the accuracy of several hip center location

prediction methods, Journal of Biomechanics, vol. 23, pp. 617-21, 1990.

10. R. Davis, S. Ounpuu, D. Tyburski, and J. Gage, A gait analysis data collection and reduction

technique, Human Movement Science, vol. 10, pp. 575-587, 1991.

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11. AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

SEGMENTAL KINEMATIC ASSESSMENT OF PLANOVALGUS FOOT SECONDARY TO CEREBRAL PALSY Speakers: Joseph Krzak, PhD, PT, PCS, Katie Konop, MS E-mail: [email protected], [email protected]

Learning Objective: How recent research is advancing our understanding of segmental foot motion and how this knowledge is being used to make better clinical decisions. ______________________________________________________________________________

Planovalgus = ‘flatfoot’

Plantar flexed hindfoot

Dorsiflexed forefoot

Flattened medial-longitudinal arch, hindfoot valgus

Most common foot deformity in children with cerebral palsy

Study goal

Provide a quantitative three-dimensional description of the skeletal segmental foot kinematics in children with planovalgus secondary to cerebral palsy

Modified Milwaukee Foot Model (MFM)

Long, et al., J Exp Clin Med 2011;3(5):239:244

4 segments: Tibia, Hindfoot, Forefoot, Hallux

3 x-ray views (sagittal, anterior/posterior, and modified coronal) used to index surface markers to underlying bony anatomy

Three-dimensional kinematics of each segment calculated relative to the proximal segment

Study details

N=5 children (8 affected feet) with planovalgus, and 10 typically developing children

All participants presented with rigid planovalgus secondary to cerebral palsy, with planned surgical correction

Static trial, weightbearing radiographs, and 3 acceptable walking trials performed

Results (see figure)

Flattened arch (Decreased hindfoot dorsiflexion and forefoot plantar flexion)

Hindfoot eversion

Forefoot abduction

The model was able to account for abnormal bony anatomy to provide accurate segmental kinematic results

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Figure: Hindfoot (relative to tibia) and forefoot (relative to hindfoot) kinematics in sagittal (column 1), coronal (column 2) and transverse (column 3) planes. Solid line is average for planovalgus group, dashed lines are +/- one standard deviation, shaded band is average normal +/- one standard deviation. Future

Larger sample size

Characterize additional pediatric and adult foot and ankle pathologies

Integrate with fluoroscopic analysis for dynamic skeletal assessment

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

KINEMATIC SUBGROUPS OF EQUINOVARUS IN CEREBRAL PALSY Speakers: Joseph Krzak, PhD, PT, PCS, Peter Smith, MD E-mail: [email protected], [email protected]

Learning Objective: How recent research is advancing our understanding of segmental foot motion and how this knowledge is being used to make better clinical decisions. ______________________________________________________________________________ Background: Equinus and varus, often found in combination resulting in equinovarus, are the most common foot and ankle deformities in children with hemiplegic cerebral palsy (CP) [1]. Because many factors contribute to the complexity of the deformity, previous reports have identified a lack of uniformity in the gait kinematics of children with equinovarus [2]. Both the hindfoot and forefoot segments contribute to the deformity in the sagittal, coronal and/or transverse planes. In addition, equinovarus can be present during the stance and/or swing phases of gait. Finally, foot and ankle deformities in children with CP can be characterized by dynamic or static soft tissue imbalance with, or without, skeletal deformity [3]. Accurate identification of the involved segment(s), plane(s), timing, and the range of motion (ROM) of the deformity is important when defining types and causes of equinovarus deformity to make accurate and effective clinical decisions.

Purpose: To identify foot types in children with equinovarus using segmental kinematics.

Hypotheses: (1) A large set of kinematic variables can be reduced to a smaller set with minimal loss of essential information. (2) Clinical foot types can be identified where the individuals are similar within a group but different from individuals in other groups.

Methods:

N = 44 24 children with equinovarus secondary to hemiplegic cerebral palsy

(12.0±4.1 yrs) 20 typically developing children (11.8±2.7 yrs)

Quantitative gait analysis: Temporal-spatial data Hindfoot and forefoot kinematics using the Milwaukee Foot Model

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A subset of forty variables were chosen Hindfoot and forefoot kinematic variables

Kinematic Peaks Position (Average or at initial contact) Range of Motion (ROM) Walking speed Age at the time of the preoperative evaluation

Principal component analysis (PCA) is a multivariate statistical procedure that converts a set of observations of possibly correlated variables into a smaller set of variables called principal components that are independent from each other.

K-means Clustering is statistical procedure where cases are divided into subgroups (or clusters).

The subgroups are created to maximize: The similarity within clusters The variation between clusters

Results:

Principal Component (PC) Construct

PC1 Sagittal hindfoot and forefoot equinus

PC2 Transverse forefoot adduction and coronal forefoot ROM

PC3 Coronal hindfoot varus

PC4 Coronal hindfoot ROM

PC5 Sagittal hindfoot ROM

PC6 Coronal/Transverse forefoot supination and transverse ROM

Cluster (n=44) Description

#1 (n=18) Control Group (Rectus)

#2 (n=5) Flexible equinovarus deformity with hindfoot involvement

#3 (n=8) Equinovarus deformity with both hindfoot and forefoot involvement

#4 (n=8) Flexible varus deformity with both hindfoot and forefoot involvement (Cavus)

#5 (n=5) Varus deformity with forefoot involvement

1. Wren, T.A., S. Rethlefsen, and R.M. Kay, Prevalence of specific gait abnormalities in children with cerebral palsy: influence of cerebral palsy subtype, age, and previous surgery. J Pediatr Orthop, 2005. 25(1): p. 79-83.

2. Theologis, T. and J. Stebbins, The use of gait analysis in the treatment of pediatric foot and ankle disorders. Foot Ankle Clin, 2010. 15(2): p. 365-82.

3. Davids, J.R., The foot and ankle in cerebral palsy. Orthop Clin North Am, 2010. 41(4): p. 579-93.

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AACPDM Pre-Conference Workshop

New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

DYNAMIC FLUOROSCOPY Speakers: Taly Gilat-Schmidt, PhD, Benjamin McHenry, PhD, Janelle Cross, MS E-mail: [email protected], [email protected], [email protected]

Learning Objective: How fluoroscopic imaging of the hindfoot is increasing our knowledge of bony hindfoot dynamics and the potential for future clinical application. ______________________________________________________________________________ Introduction to Fluoroscopy

Overview of Fluoroscopy Imaging

Image formation

Systems components

Clinical use

Ionizing Radiation

Dangers of ionizing radiation

Quantification of radiation dose

Estimates of radiation risk

Fluoroscopy in Foot Modeling

Why?

Errors associated with external markers

Foot anatomy makes subcutaneous joints difficult to model

Alternative methods are invasive

Hardware

Fluoroscopy unit

Walkway

Force plate

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Camera

Image manipulation

Image correction

Image magnification

Global referencing

2D Fluoroscopic hindfoot model

Kinematics

Kinetics

Biplane Fluoroscopy in Foot Modeling

Set-up

Walkway with force plate

X-ray sources and image intensifiers

Calibration

Image distortion correction

Volume calibration

Bone Models

MRI of foot

Segmentation of Bones

Model-Based tracking

Input: Bone models and image sequences in virtual space

Output: Six degrees of freedom of bones

Kinematics and Kinetics of talocrural and subtalar joints

Inverse Dynamics and ground reaction forces

Clinical applications

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New Clinical Horizons and Emerging Mobility Technologies – A Research Driven Process

PASSIVE STRETCHING AND ACTIVE MOVEMENT TRAINING USING A PORTABLE

REHABILITATION ROBOT IN CHILDREN WITH CEREBRAL PALSY Speakers: Li-Qun Zhang, PhD, Deborah Gaebler-Spira, MD E-mail: [email protected], [email protected] Learning Objective: Important features of robotic assisted movement therapy and how this technology can be useful in the clinician’s treatment arena and how gaming strategies are integrated with therapy demands in the current clinical environment. ______________________________________________________________________________ Ankle impairments are closely associated with functional limitations in children with cerebral palsy

(CP). Passive stretching has been commonly used to increase range of motion (ROM) of the impaired

ankle in children with CP. Improving motor control is also a focus of physical therapy in treating

children with CP. However, there is a lack of convenient and effective ways to conduct controlled

passive stretching and motivating active movement training with quantitative outcome evaluation.

The efficacy of combined passive stretching and active movement training with motivating games was

investigated using a portable rehabilitation robot.

Twelve children with mild to moderate spastic CP participated in robotic rehabilitation three times per

week for six weeks. Each session consisted of 20-minute passive stretching followed by 30-minute

active movement training, and ended with 10-minute passive stretching. Passive ROM (PROM), active

ROM (AROM), dorsiflexor and plantarflexor muscle strength, selective control assessment of the lower

extremity (SCALE) and functional outcome measures (Pediatric Balance Scale, 6-min walk, and timed

up-and-go) were evaluated before and after the six-week intervention.

It was found that significant increases were observed in dorsiflexion PROM, AROM, and dorsiflexor

muscle strength. Spasticity of the ankle musculature was significantly reduced. Selective motor control

improved significantly (p=0.005). Functionally, participants showed significantly improved balance

(p=0.0025) and increased walking distance within 6 minutes.

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Key Points, Supportive Information

Passive stretching helped increase ROM and reduce stiffness in children with CP.

Active movement training with engaging games motivates children in improving motor control.

The passive and active training combination demonstrated improvements in joint biomechanical properties, motor control performance, and functional capability in balance and mobility.

Key References

Wu, Y.-N., Hwang, M., Ren, Y., Gaebler-Spira, D. J., and Zhang, L.-Q., 2011. Combined passive

stretching and active movement rehabilitation of lower-limb impairments in children with

cerebral palsy using a portable robot. Neurorehab Neural Repair. 25, 378-385.

Waldman, G., Yang, C.-Y., Ren, Y., Liu, L., Guo, X., Harvey, R. L., Roth, E. J., and Zhang, L.-Q., 2013.

Effects of Robot-Assisted Passive Stretching and Active Movement Training of Ankle and

Mobility Impairments in Stroke. Neurorehab Neural Repair. 32, 625-634.