A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas...

18
A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014 ASCO Annual Meeting

TAGS:

Transcript of A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas...

Page 1: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 2: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Disclosures

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 3: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Background

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 4: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Psychostimulants and Primary Brain Tumors

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 5: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Methods

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 6: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Elgibility Criteria

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 7: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Statistics

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 8: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Statistics

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 9: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Consort Diagram

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 10: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Patient Characteristics

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 11: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Toxicity Attributed to Treatment

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 12: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Primary Endpoint

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 13: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Secondary Endpoint

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 14: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Secondary Endpoint

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 15: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Secondary Endpoint

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 16: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Conclusions

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 17: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Discussion

Presented By Eudocia Lee at 2014 ASCO Annual Meeting

Page 18: A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy Presented By Eudocia Lee at 2014.

Acknowledgments

Presented By Eudocia Lee at 2014 ASCO Annual Meeting


Paediatric gliomas denise sheer

Paediatric gliomas denise sheer

INTRACRANIAL GLIOMAS- RADIOLOGY, DIAGNOSIS AND MANAGEMENT.

INTRACRANIAL GLIOMAS- RADIOLOGY, DIAGNOSIS AND MANAGEMENT.

Multidimensional scaling of diffuse gliomas: application ... · Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system

Multidimensional scaling of diffuse gliomas: application ... · Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system

Magnetic Resonance Imaging of Gliomas

Magnetic Resonance Imaging of Gliomas

Hypothalamic gliomas in children - BMJ

Hypothalamic gliomas in children - BMJ

Johns Hopkins Medicine Medicare Plan Advantage MD PPO ... · Prior Authorization Group ARMODAFINIL Drug Names ARMODAFINIL PA Indication Indicator All FDA-approved Indications Off-label

Johns Hopkins Medicine Medicare Plan Advantage MD PPO ... · Prior Authorization Group ARMODAFINIL Drug Names ARMODAFINIL PA Indication Indicator All FDA-approved Indications Off-label

Epigenetic Aberrations and Therapeutic Implications in Gliomas

Epigenetic Aberrations and Therapeutic Implications in Gliomas

Low grade gliomas : management and controversies

Low grade gliomas : management and controversies

Cns tumor, gliomas

Cns tumor, gliomas

2019 armodafinil (generic Nuvigil ) Prior Authorization ... · 2019 armodafinil (generic Nuvigil®) Prior Authorization Request Page 1 of 2 (You must complete both pages.) Fax completed

2019 armodafinil (generic Nuvigil ) Prior Authorization ... · 2019 armodafinil (generic Nuvigil®) Prior Authorization Request Page 1 of 2 (You must complete both pages.) Fax completed

Empress Athenais-Eudocia,

Empress Athenais-Eudocia,

High grade gliomas diagnosis management and controversies

High grade gliomas diagnosis management and controversies

The Empress Eudocia

The Empress Eudocia

Magnetic Resonance Imaging of Gliomas - Digital.CSICdigital.csic.es/bitstream/10261/78152/1/Magnetic resonance.pdf · Magnetic Resonance Imaging of Gliomas Pilar López-Larrubia,

Magnetic Resonance Imaging of Gliomas - Digital.CSICdigital.csic.es/bitstream/10261/78152/1/Magnetic resonance.pdf · Magnetic Resonance Imaging of Gliomas Pilar López-Larrubia,

Microglia immunophenotyping in gliomas

Microglia immunophenotyping in gliomas

Chemotherapy in gliomas

Chemotherapy in gliomas

Second Surgery in Insular Low-Grade Gliomas

Second Surgery in Insular Low-Grade Gliomas

NSS 53132 Armodafinil Increases Wakefulness by Mechanisms That Extend 050214

NSS 53132 Armodafinil Increases Wakefulness by Mechanisms That Extend 050214

HIGHLIGHTS OF PRESCRIBING INFORMATION use …Modafinil and armodafinil are very closely related. Therefore, the incidence and type of psychiatric symptoms associated with armodafinil

HIGHLIGHTS OF PRESCRIBING INFORMATION use …Modafinil and armodafinil are very closely related. Therefore, the incidence and type of psychiatric symptoms associated with armodafinil

INTRACRANIAL GLIOMAS- RADIOLOGY, DIAGNOSIS AND MANAGEMENT

INTRACRANIAL GLIOMAS- RADIOLOGY, DIAGNOSIS AND MANAGEMENT