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![Page 1: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/1.jpg)
A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force
Florencia Rosetti, Yunfeng Chen, Mehmet Sen, Elizabeth Thayer, Veronica Azcutia, Jan M. Herter, F. William Luscinskas, Xavier Cullere, Cheng Zhu, Tanya N. Mayadas
Cell Reports Volume 10, Issue 10, Pages 1655-1664 (March 2015)
DOI: 10.1016/j.celrep.2015.02.037
Copyright © 2015 The Authors Terms and Conditions
![Page 2: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/2.jpg)
Figure 1
Cell Reports 2015 10, 1655-1664DOI: (10.1016/j.celrep.2015.02.037) Copyright © 2015 The Authors Terms and Conditions
![Page 3: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/3.jpg)
Figure 2
Cell Reports 2015 10, 1655-1664DOI: (10.1016/j.celrep.2015.02.037) Copyright © 2015 The Authors Terms and Conditions
![Page 4: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/4.jpg)
Figure 3
Cell Reports 2015 10, 1655-1664DOI: (10.1016/j.celrep.2015.02.037) Copyright © 2015 The Authors Terms and Conditions
![Page 5: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/5.jpg)
Figure 4
Cell Reports 2015 10, 1655-1664DOI: (10.1016/j.celrep.2015.02.037) Copyright © 2015 The Authors Terms and Conditions
![Page 6: A Lupus-Associated Mac-1 Variant Has Defects in Integrin Allostery and Interaction with Ligands under Force Florencia Rosetti, Yunfeng Chen, Mehmet Sen,](https://reader036.fdocuments.us/reader036/viewer/2022082816/56649d765503460f94a57509/html5/thumbnails/6.jpg)
Cell Reports 2015 10, 1655-1664DOI: (10.1016/j.celrep.2015.02.037) Copyright © 2015 The Authors Terms and Conditions