A Bright Future Lies Ahead for Molecular Imaging
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A Bright Future Lies Ahead for Molecular Imaging Roberto G. Aranibar, Research Analyst Medical Imaging February 9, 2011
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Transcript of A Bright Future Lies Ahead for Molecular Imaging
A Bright Future Lies Ahead for Molecular Imaging
Roberto G. Aranibar, Research Analyst
Medical Imaging
February 9, 2011
Today’s Presenters
Roberto G. Aranibar,
Research Analyst
Frost & Sullivan
2
Introduction
Agenda
I. Molecular Imaging (MI): Introduction and Background
II. Ongoing Developments in MI
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Molecular Imaging (MI): Introduction and Background
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Molecular Imaging (MI)
• Definition
• Unique Advantages
• Tools & Objective
Molecular imaging in cardiac, pulmonary, and neurological imaging applications Source: www.snm.org
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• Tools & Objective
• Modalities/Techniques
• Nuclear Medicine
• Scintigraphy
• SPECT
• PET
• Optical (Preclinical)
• Fluorescence
• Bioluminescence
• Hybrid Techniques
The power of molecular imaging. A patient with a history of breast
cancer is suspected of having a chest wall recurrence. CT was
indeterminate, but PET was clearly positive. Source:
www.cancernetwork.com
Clinical MI Market Performance (U.S.)
Key Clinical MI Markets
• NM
• PET
General Trend
• Downward since 20030
100
200
300
400
500
600
Re
ve
nu
es
($
Mil
lio
n)
Nuclear Medicine PET
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Outlook
• 2010?
• 2011 and beyond?
Annual Revenues in Key Clinical MI Markets (U.S., new
equipment only). Source: Frost & Sullivan
0
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
Ongoing Developments in Molecular Imaging
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Increased Access to MI
Availability of Radiopharmaceuticals
• Expanding Radiopharmacy Networks
• More Affordable Costs
• Increased Efforts to Secure Supply of
Medical Radioisotopes
Access to MI Research Tools
• Small, Simple and Affordable MI Solutions
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• Small, Simple and Affordable MI Solutions
Sofie Biosciences’ Benchtop Preclinical PET
Imaging Solution. Source: www.sofiebio.com
Map of commercial cyclotron/FDG radiopharmacies in
the United States. Source: UCLA
Novel Probes
Nuclear Radioisotopes
• For Neurology
• Amyvid (PET)
• 18F-Flutemetamol (PET)
• DaTSCAN (SPECT)
• 18F-AV-133 (SPECT)
• For Oncology
• Hypoxia Agents 18F-FMISO (PET)
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• Hypoxia Agents 18F-FMISO (PET)
• 18F-FLT
Optical Fluorescence
• For Intraoperative Cancer Visualization
• Chlorotoxin-Cy5.5Source: www.chem.monash.edu
New Instrument Technologies
• New Solid-State Technologies
• Whole-body PET/MR Imaging Solutions
GE Healthcare’s PET/CT+MRI Tri-modality Solution. Source: GE Healthcare
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Philips Healthcare’s Ingenuity TF PET/MR
System. Source: www.gezondheidskrant.nl/
Siemens Healthcare’s Biograph mMR
Scanner. Source: Siemens Healthcare
Other Ongoing Developments
Emerging Clinical Applications
• Molecular Breast Imaging (MBI)
• PEM (Positron Emission
Mammography)
• BSGI (Breast-Specific Gamma
Imaging)
• Dedicated Cardiac PET The Naviscan PEM Scanner for detection,
staging, and management of breast cancer.
Source: www.naviscan.com
The Dilon 6800 BSGI Camera.
Source: www.dilon.com
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Expanding Reimbursement Coverage
• April 2009 – FDG-PET for an expanded
set of cancer indications
• February 2011 – 18F-NaF
Source: www.naviscan.com
Positron’s Attrius Cardiac PET Scanner.
Source: www.positron.com
Conclusion
100
200
300
400
500
600
Re
ve
nu
es
($
Mil
lio
n)
Nuclear Medicine PETMarket Outlook
• NM
• PET
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0
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
Annual Revenues in Key Clinical MI Markets and Preliminary
Outlook (U.S., new equipment only). Source: Frost & Sullivan
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Antonio Garcia
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