$99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new...

6
US & Canada | 1-877-772-2622 Outside NA | 650-583-6688 B e t t e r A n t i b o d i e s B e t t e r S c i e n c e Antibody Satisfaction Guarantee www.epitomics.com ï More diverse epitope recognition ï High specificity and affinity ï Improved response to mouse antigens ï Highly validated - every antibody tested in WB, IHC, ICC, Flow Cytometry, and IP MONO CDX2 RabMAb Parafn-embedded human colon tissue stained with Epitomics’ CDX2 RabMAb (Cat.# 2475-1) and Vendor A’s CDX2 Mouse Monoclonal under optimal conditions CDX2 Mouse MAb RABBIT MONOCLONAL MOUSE MONOCLONAL THE RABBIT MONOCLONAL ADVANTAGE Find out more @ www.epitomics.com/advantage Æ ) provide the combined benefits of superior antigen recognition of the rabbit immune system with the specificity and consistency of a monoclonal antibody, bringing you the highest quality antibody possible. Over 4000 RabMAbs Æ online, visit Æ www.epitomics.com $99 SPECIAL OFFER ANTIBODY SPECIAL www.epitomics.com/promo Find out more @

Transcript of $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new...

Page 1: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

US & Canada | 1-877-772-2622

Outside NA | 650-583-6688

Bet

ter Ant ibo

d

ies

B

et t e r S c i

enc

e

Antibody Satisfaction Guarantee www.epitomics.com

ï More diverse epitope recognition

ï High specificity and affinity

ï Improved response to mouse antigens

ï Highly validated - every antibody tested in WB, IHC,

ICC, Flow Cytometry, and IP

MONO

CDX2 RabMAb

Parafn-embedded human colon tissue stained with Epitomics’ CDX2 RabMAb (Cat.#

2475-1) and Vendor A’s CDX2 Mouse Monoclonal under optimal conditions

CDX2 Mouse MAb

RABBIT MONOCLONAL MOUSE MONOCLONAL

THE RABBIT MONOCLONAL ADVANTAGE

Find out more @ www.epitomics.com/advantage

Æ)

provide the combined benefits of superior

antigen recognition of the rabbit immune

system with the specificity and consistency

of a monoclonal antibody, bringing you the

highest quality antibody possible.

Over 4000 RabMAbsÆ online, visitÆ

www.epitomics.com

$99SPECIAL OFFER

ANTIBODYSPECIAL

www.epitomics.com/promoFind outmore @

Page 2: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

You never go into the lab without your goggles, so why would youstart your project without SciFinder®? Used by top researchers,

SciFinder is the only tool that provides access to the mostcomprehensive and trustworthy chemistry-related content. And

that’s why SciFinder is the choice for chemistry research.TM

Find out more at www.cas.org.

THE SECOND MOST NECESSARY

EQUIPMENT IN THE LAB?

Page 3: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

There’s only oneDr. Shirley Malcom

Career advice I Job postings I Job Alerts I Career Forum I Crafting resumes/CVs I Preparing for interviews

For your career in science, there’s only one

Careers

ScienceCareers.org

o Dr. Shirley Malcom, born and raised in the segregated South more than 65 years ago, a career based

on her studies in science seemed even less likely than the launch of the Soviet’s Sputnik. But with Sputnik’s

success, the Space Race officially started and, in an instant, brought a laser-like focus to science education

and ways to deliver a proper response. Not long after, Dr. Malcom entered the picture.

Although black schools at the time received fewer dollars per student and did not have sufficient

resources to maintain their labs at a level equivalent to the white schools, Dr. Malcom found her way to the

University of Washington where she succeeded in obtaining a B.S. in spite of the difficulties of being an

African American woman in the field of science. From there she went on to earn a Ph.D. in ecology from

Penn State and held a faculty position at the University of North Carolina, Wilmington.

Dr. Malcom has served at the AAAS in multiple capacities, and is presently Head of the Directorate for

Education and Human Resources Programs. Nominated by President Clinton to the National Science Board, she

also held a position on his Committee of Advisors on Science and Technology. She is currently a member of the

Caltech Board of Trustees, a Regent of Morgan State University, and co-chair of the Gender Advisory Board of

the UN Commission on Science and Technology for Development. She has held numerous other positions of

distinction and is the principal author of The Double Bind: The Price of Being a MinorityWoman in Science.

Of her active career in science, Dr. Malcom says, “I guess I have become a poster child for taking

one’s science background and using that in many other ways: we ask questions; we try to under-

stand what we find; we consider what evidence we would need to confirm or refute hypotheses.

And that happens in whatever setting one finds oneself.”

At Science we are here to help you in your own scientific career with expert career advice,

forums, job postings, and more — all for free. Visit Science today at ScienceCareers.org.

T

Page 4: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

1101www.sciencemag.org/products SCIENCE VOL 338 23 NOVEMBER 2012

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or

materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

New Products

Produced by the Science/AAAS Custom Publishing Office LLIIFFEE SSCCIIEENNCCEE TTEECCHHNNOOLLOOGGIIEESS

AUTOMATED COMPOUND QUALITY CONTROL

The Brooks Plate Auditor is a fast, accurate, and noninvasive tool

for identi� cation of precipitate and empty wells in compound and

screening plates. The new Plate Auditor is the result of a success-

ful collaboration with the Scripps Research Institute. The new Plate

Auditor is designed to evaluate the quality of microplate-based com-

pound samples for precipitation and liquid volume prior to use in

compound management and high throughput screening activities.

The system rapidly analyzes plates to automatically verify sample

integrity thus eliminating the need for extensive manual quality con-

trol. The ability of the instrument to provide sample color information

makes the Plate Auditor a unique option for monitoring sample qual-

ity over time, and identifying wells with artifacts which may interfere

with or invalidate screening results.

Brooks Life Science Systems

For info: 978-262-2400 www.brooks.com

ELECTROCOMPETENT CELLSCloneCatcher Gold DH5G Electrocompent E. coli cells exhibit ex-

tremely high electroporation ef� ciencies that approach the theoreti-

cal maximum of 3.4 x 1011 cfu/�g pUC19 DNA. Transferring exog-

enous DNA into E. coli is a standard laboratory method for cloning

genes and constructing cDNA, genomic, and epitope libraries. The

limiting factor in many library-screening efforts or multiple fragment

ligations is the ef� ciency by which DNA can be introduced into E.

coli. Electroporation is one method to ef� ciently introduce DNA into

E. coli. CloneCatcher Gold cells meet the needs of scientists that are

seeking to � nd rare clones or are building complex or metagenomic

libraries. CloneCatcher Gold signi� cantly outperforms all other com-

mercially available Electrocompetent Cells when introducing ligated

DNA. When the amount of input DNA is limited, CloneCatcher Gold

enhances your likelihood of success. CloneCatcher Gold requires

less topoisomerase-loaded vector and therefore can reduce the

overall operating costs.

AMS Biotechnology

For info: +44-(0)-1235-828200 www.amsbio.com

HPLC COLUMNA new 5 �m particle has been added to the Kinetex core-shell prod-

uct line. As the largest diameter particle in the family, Kinetex 5 �m

core-shell columns deliver better performance than 3 �m or 5 �m ful-

ly porous offerings, with no increase in backpressure. In fact, the new

5 �m media provides 90% higher average ef� ciencies compared to

the same size fully porous columns and little to no method devel-

opment is required to achieve improved performance on standard

high-performance liquid chromatography (HPLC) systems. Chroma-

tographers can simply substitute these columns into reversed phase

HPLC methods that use traditional fully porous columns. Kinetex

5 �m delivers increased resolution and higher ef� ciencies and ex-

tends the scalability and portability of the product line. With the cur-

rent range of available particle sizes, including 1.3 �m, 1.7 �m, and

2.6 �m, the same method can be easily transferred from UHPLC to

HPLC to Preparative LC with Kinetex Core-Shell Technology

Phenomenex

For info: 310-212-0555 www.phenomenex.com

THERMAL TEST ENCLOSURES A line of thermal test enclosures for the ThermoJet ES precision

temperature cycling system is now available. The thermal enclo-

sures provide highly accurate testing and processing of temperature

sensitive electronic products. Available in either clamshell or hood

con� gurations, the thermal test enclosures may be used to isolate a

device under test (DUT) at a precise temperature insulated from ex-

ternal conditions, thereby providing the optimal conditions for highly

accurate testing. Maintaining a uniform stable temperature with re-

al-time thermal measurements on a DUT, the new thermal enclo-

sures deliver unmatched test accuracy and precision. The thermal

enclosures allow temperature testing of a variety of device sizes into

almost any test setup, enabling characterization, quali� cation, and

fault isolation on components or production level testing. All thermal

test enclosures are electrostatic discharge-free and/or electromag-

netic interference shielded.

SP Scienti� c

For info: 845-255-5000 www.spscienti� c.com

ELECTRIC CAPPERDesigned to work with all sample storage 96-format tube and rack combinations,

without use of adapters, the Univo Electric Capper CP480 sets a new bench-

mark for ease of use, versatility, and speed of operation. Operating as a stand-

alone benchtop unit the compact Univo Electric Capper is able to uniformly cap a

complete rack of 96 sample storage tubes in only four to nine secondsóless than

half the time of competitive systems. The versatile Univo Electric Capper can cap

all Micronic plug style caps: capmats, capbands, and capclusters made of TPE,

EVA, or other materials on 96-format Micronic tubes and racks. The capper is also

compatible with most other brands of tubes and caps. The Univo Electric Cap-

per is extremely easy-to-use. For capping, simply place the rack � lled with tubes

in the sample holder and place a capmat, capband, or capcluster on the tubes.

MicronicFor info: +31-320-277070 www.micronic.com

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

Page 5: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

Announcing our new partnership with NASA Federal Credit Union

Dear Member:

AAAS is committed to ofering you member benefts that ft your needs and make your membership

more valuable.

With that in mind AAAS is embarking on a new partnership with NASA Federal Credit Union that will

provide you with access to a wide range of fnancial tools and products. Like AAAS, NASA Federal Credit

Union is dedicated to serving the scientifc community. This shared perspective is just one of the many

reasons that we are embarking on this partnership.

As you may know, we have recently ended our banking relationship with Bank of America, but we’re

confdent that our new partnership with NASA FCU will provide you with a superior banking experience.

NASA FCU ofers members better ways to save and smarter ways to borrow with friendly, professional

service – along with anytime, anywhere account access.

Moreover, unlike other fnancial institutions that have public stockholders, NASA FCU is a not-for-proft

fnancial cooperative where being a member means being an owner, too. And as a member/owner,

you will enjoy unique benefts like: better loan rates, higher dividends and state-of-the-art products and

services.

We’ll be sending you more information about this great new beneft over the coming months. In the

meantime, be sure to visit nasafcu.com/AAASpackage to apply for the new AAAS Platinum Advantage

Rewards or Platinum Cash Rewards credit cards. You can also take a sneak peek at the AAAS Check Card

and Checks coming soon.

Sincerely,

Ian King

Director of Marketing and Membership, AAAS

Page 6: $99SPECIAL · 2012-12-07 · without use of adapters, the Univo Electric Capper CP480 sets a new bench-mark for ease of use, versatility, and speed of operation. Operating as a stand-alone

For experimental details, additionalinformation, and a complete list of availableXP® monoclonal antibodies visit…

XP®

Monoclonal Antibodies,one antibody, multiple applications

Above: Confocal IF analysis of rat testis using Miwi (D92B7) XP® Rabbit mAb #6915 (red

pseudocolor) and Vimentin (D21H3) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate) #9856

(blue pseudocolor). Actin filaments were labeled with DY-554 phalloidin (green pseudocolor).

XP® monoclonal antibodies are a line of high quality

rabbit monoclonal antibodies exclusively available from

Cell Signaling Technology. Any product labeled with XP

has been carefully selected based on superior performance

in the most relevant applications.

XP monoclonal antibodies are generated using XMT®

technology, a proprietary monoclonal method developed

at Cell Signaling Technology. This technology provides

access to a broad range of antibody-producing B cells

unattainable with traditional monoclonal technologies,

allowing more comprehensive screening and the

identification of XP monoclonal antibodies.

Unparalleled product quality, validation,and technical support.

eXceptional specificityAs with all of our antibodies, the antibody is specific to your target of

interest, saving you valuable time and resources.

+eXceptional sensitivityThe antibody will provide a stronger signal for your target protein in

cells and tissues, allowing you to monitor expression of low levels of

endogenous proteins, saving you valuable materials.

+eXceptional stability and reproducibilityXMT technology combined with our stringent quality control ensures

maximum lot-to-lot consistency and the most reproducible results.

=eXceptional Performance™

XMT technology coupled with our extensive antibody validation and

stringent quality control delivers XP monoclonal antibodies with

eXceptional Performance in the widest range of applications.

©2012

CellS

ignalingTechnology,Inc.

XM

T®,X

,eXceptionalP

erformance™

,CS

T™,and

CellS

ignalingTechnology

®are

trademarks

ofCellS

ignaling

Technology,Inc.A

lexaFlu

or®

isa

tradem

arkof

Molecu

larProb

es,In

c.Antibodies and Related Reagents for Signal Transduction Research

Orders (toll-free) 1-877-616-2355 | Technical support (toll-free) 1-877-678-8324 [email protected] | Inquiries [email protected] | Environmental Commitment eco.cellsignal.com

www.cellsignal.com